14-Deoxy-11,12-didehydroandrographolide induces DDIT3-dependent endoplasmic reticulum stress-mediated autophagy in T-47D breast carcinoma cells

Toxicology and Applied Pharmacology

Volumn 300, Issue , 2016, Pages 55-69

  Tan, Heng Kean ^a,b   Muhammad, Tengku Sifzizul Tengku ^a,c   Tan, Mei Lan ^a,b  

^a Kemeneterian Sains Teknologi dan Inovasi   (Malaysia)

^b ADVANCED MEDICAL AND DENTAL INSTITUTE   (Malaysia)

^c UNIVERSITI MALAYSIA TERENGGANU   (Malaysia)

Author keywords

14 Deoxy 11,12 didehydroandrographolide; Autophagy; DDIT3 CHOP; Endoplasmic reticulum stress

Indexed keywords

14 DEOXY 11,12 DIDEHYDROANDROGRAPHOLIDE; CALCIUM; CYTOTOXIC AGENT; DITERPENOID; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MITOGEN ACTIVATED PROTEIN KINASE P38; UNCLASSIFIED DRUG; 14-DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE; DITERPENE; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BREAST CARCINOMA; CARCINOMA CELL; CELL VACUOLE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; GENE SILENCING; MITOCHONDRIAL MEMBRANE POTENTIAL; SIGNAL TRANSDUCTION; UPREGULATION; BIOSYNTHESIS; BREAST NEOPLASMS; DRUG EFFECTS; HUMAN; METABOLISM; MITOCHONDRIAL MEMBRANE; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

AUTOPHAGY; BREAST NEOPLASMS; CELL LINE, TUMOR; DITERPENES; ENDOPLASMIC RETICULUM STRESS; HUMANS; MAP KINASE SIGNALING SYSTEM; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIAL MEMBRANES; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; TRANSCRIPTION FACTOR CHOP; UP-REGULATION;

EID: 84962820620     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2016.03.017     Document Type: Article

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