Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to cirsimaritin-induced apoptosis in human gallbladder carcinoma GBC-SD cells

Cancer Letters

Volumn 295, Issue 2, 2010, Pages 252-259

  Quan, Zhiwei ^a   Gu, Jun ^a   Dong, Ping ^a   Lu, Jianhua ^a   Wu, Xiangsong ^b   Wu, Wenguang ^b   Fei, Xiaozhou ^b   Li, Songgang ^a   Wang, Yong ^b   Wang, Jianwei ^b   Liu, Yingbin ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Apoptosis; Cirsimaritin; Endoplasmic reticulum stress; Gallbladder carcinoma; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CIRSIMARITIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; GALLBLADDER CARCINOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; ENDOPLASMIC RETICULUM; FLAVONES; GALLBLADDER NEOPLASMS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTOR CHOP;

EID: 77954032171     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.03.008     Document Type: Article

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