메뉴 건너뛰기




Volumn 11, Issue 4, 2016, Pages 655-663

Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry

Author keywords

[No Author keywords available]

Indexed keywords

DYE; LIPOCORTIN 5; NUCLEIC ACID;

EID: 84962240485     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2016.028     Document Type: Article
Times cited : (96)

References (52)
  • 1
    • 0032493870 scopus 로고    scopus 로고
    • Differential requirement for caspase 9 in apoptotic pathways in vivo
    • Hakem, R. et al. Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 94, 339-352 (1998).
    • (1998) Cell , vol.94 , pp. 339-352
    • Hakem, R.1
  • 2
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin v
    • Vermes, I., Haanen, C., Steffens-Nakken, H. & Reutelingsperger, C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J. Immunol. Methods 184, 39-51 (1995).
    • (1995) J. Immunol. Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 3
    • 84860381346 scopus 로고    scopus 로고
    • Actin-binding complementarity-determining region 2 of variable heavy chain from monoclonal antibody C7 induces apoptosis in several human tumor cells and is protective against metastatic melanoma
    • Arruda, D. C. et al. actin-binding complementarity-determining region 2 of variable heavy chain from monoclonal antibody C7 induces apoptosis in several human tumor cells and is protective against metastatic melanoma. J. Biol. Chem. 287, 14912-14922 (2012).
    • (2012) J. Biol. Chem. , vol.287 , pp. 14912-14922
    • Arruda, D.C.1
  • 4
    • 0034604701 scopus 로고    scopus 로고
    • Free cholesterol loading of macrophages induces apoptosis involving the Fas pathway
    • Yao, P. M. & Tabas, I. Free cholesterol loading of macrophages induces apoptosis involving the Fas pathway. J. Biol. Chem. 275, 23807-23813 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 23807-23813
    • Yao, P.M.1    Tabas, I.2
  • 5
    • 84863811010 scopus 로고    scopus 로고
    • A role for GPx3 in activity of normal and leukemia stem cells
    • Herault, O. et al. A role for GPx3 in activity of normal and leukemia stem cells. J. Exp. Med. 209, 895-901 (2012).
    • (2012) J. Exp. Med. , vol.209 , pp. 895-901
    • Herault, O.1
  • 6
    • 84856150216 scopus 로고    scopus 로고
    • UCP2 inhibits ROS-mediated apoptosis in A549 under hypoxic conditions
    • Deng, S. et al. UCP2 inhibits ROS-mediated apoptosis in A549 under hypoxic conditions. PLoS ONE 7, e30714 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e30714
    • Deng, S.1
  • 7
    • 7244221520 scopus 로고    scopus 로고
    • Apoptotic bodies from endothelial cells enhance the number and initiate the differentiation of human endothelial progenitor cells in vitro
    • Hristov, M., Erl, W., Linder, S. & Weber, P. C. Apoptotic bodies from endothelial cells enhance the number and initiate the differentiation of human endothelial progenitor cells in vitro. Blood 104, 2761-2766 (2004).
    • (2004) Blood , vol.104 , pp. 2761-2766
    • Hristov, M.1    Erl, W.2    Linder, S.3    Weber, P.C.4
  • 8
    • 0037108605 scopus 로고    scopus 로고
    • Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages
    • Li, N., Wang, M., Oberley, T. D., Sempf, J. M. & Nel, A. E. Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages. J. Immunol. 169, 4531-4541 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 4531-4541
    • Li, N.1    Wang, M.2    Oberley, T.D.3    Sempf, J.M.4    Nel, A.E.5
  • 9
    • 0031985647 scopus 로고    scopus 로고
    • Annexin V-affinity assay: A review on an apoptosis detection system based on phosphatidylserine exposure
    • van Engeland, M., Nieland, L. J., Ramaekers, F. C., Schutte, B. & Reutelingsperger, C. P. Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 31, 1-9 (1998).
    • (1998) Cytometry , vol.31 , pp. 1-9
    • Van Engeland, M.1    Nieland, L.J.2    Ramaekers, F.C.3    Schutte, B.4    Reutelingsperger, C.P.5
  • 10
    • 0027989808 scopus 로고
    • Annexin v for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman, G. et al. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84, 1415-1420 (1994).
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1
  • 11
    • 84934969509 scopus 로고    scopus 로고
    • Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cells
    • Kozako, T. et al. Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cells. Sci. Rep. 5, 11345 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 11345
    • Kozako, T.1
  • 12
    • 84930621914 scopus 로고    scopus 로고
    • Spontaneous gammaH2AX foci in human solid tumor-derived cell lines in relation to p21WAF1 and WIP1 expression
    • Mirzayans, R. et al. Spontaneous gammaH2AX foci in human solid tumor-derived cell lines in relation to p21WAF1 and WIP1 expression. Int. J. Mol. Sci. 16, 11609-11628 (2015).
    • (2015) Int. J. Mol. Sci. , vol.16 , pp. 11609-11628
    • Mirzayans, R.1
  • 13
    • 76749086068 scopus 로고    scopus 로고
    • Molecular mechanisms of late apoptotic/necrotic cell clearance
    • Poon, I. K., Hulett, M. D. & Parish, C. R. Molecular mechanisms of late apoptotic/necrotic cell clearance. Cell Death Differ. 17, 381-397 (2010).
    • (2010) Cell Death Differ. , vol.17 , pp. 381-397
    • Poon, I.K.1    Hulett, M.D.2    Parish, C.R.3
  • 14
    • 84896690342 scopus 로고    scopus 로고
    • Apoptotic cell clearance: Basic biology and therapeutic potential
    • Poon, I. K., Lucas, C. D., Rossi, A. G. & Ravichandran, K. S. Apoptotic cell clearance: basic biology and therapeutic potential. Nat. Rev. Immunol. 14, 166-180 (2014).
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 166-180
    • Poon, I.K.1    Lucas, C.D.2    Rossi, A.G.3    Ravichandran, K.S.4
  • 15
    • 0026556554 scopus 로고
    • Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry
    • Schmid, I., Krall, W. J., Uittenbogaart, C. H., Braun, J. & Giorgi, J. V. Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry. Cytometry 13, 204-208 (1992).
    • (1992) Cytometry , vol.13 , pp. 204-208
    • Schmid, I.1    Krall, W.J.2    Uittenbogaart, C.H.3    Braun, J.4    Giorgi, J.V.5
  • 16
    • 34250613948 scopus 로고    scopus 로고
    • In vitro measurement of cell death with the annexin A5 affinity assay
    • van Genderen, H. et al. In vitro measurement of cell death with the annexin A5 affinity assay. Nat. Protoc. 1, 363-367 (2006).
    • (2006) Nat. Protoc. , vol.1 , pp. 363-367
    • Van Genderen, H.1
  • 17
    • 79960944057 scopus 로고    scopus 로고
    • Membrane vesicles, current state-of-The-art: Emerging role of extracellular vesicles
    • Gyorgy, B. et al. Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles. Cell. Mol. Life Sci. 68, 2667-2688 (2011).
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 2667-2688
    • Gyorgy, B.1
  • 18
    • 84897897084 scopus 로고    scopus 로고
    • Unexpected link between an antibiotic, pannexin channels and apoptosis
    • Poon, I. K. et al. Unexpected link between an antibiotic, pannexin channels and apoptosis. Nature 507, 329-334 (2014).
    • (2014) Nature , vol.507 , pp. 329-334
    • Poon, I.K.1
  • 19
    • 84935896741 scopus 로고    scopus 로고
    • A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-A-string membrane structure
    • Atkin-Smith, G. K. et al. A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure. Nat. Commun. 6, 7439 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 7439
    • Atkin-Smith, G.K.1
  • 20
    • 0242609099 scopus 로고    scopus 로고
    • Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine
    • Johansson, A. C., Steen, H., Ollinger, K. & Roberg, K. Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine. Cell Death Differ. 10, 1253-1259 (2003).
    • (2003) Cell Death Differ. , vol.10 , pp. 1253-1259
    • Johansson, A.C.1    Steen, H.2    Ollinger, K.3    Roberg, K.4
  • 21
    • 24944582139 scopus 로고    scopus 로고
    • Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts
    • Friis, M. B. et al. Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts. J. Physiol. 567, 427-443 (2005).
    • (2005) J. Physiol. , vol.567 , pp. 427-443
    • Friis, M.B.1
  • 22
    • 1442354888 scopus 로고    scopus 로고
    • Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis
    • Brakenhielm, E. et al. Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc. Natl. Acad. Sci. USA 101, 2476-2481 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 2476-2481
    • Brakenhielm, E.1
  • 23
    • 84877600259 scopus 로고    scopus 로고
    • U937 variant cells as a model of apoptosis without cell disintegration
    • Stasilojc, G. et al. U937 variant cells as a model of apoptosis without cell disintegration. Cell. Mol. Biol. Lett. 18, 249-262 (2013).
    • (2013) Cell. Mol. Biol. Lett. , vol.18 , pp. 249-262
    • Stasilojc, G.1
  • 24
    • 0035960736 scopus 로고    scopus 로고
    • An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin-and myosin-dependent mechanism
    • Rosenblatt, J., Raff, M. C. & Cramer, L. P. An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin-and myosin-dependent mechanism. Curr. Biol. 11, 1847-1857 (2001).
    • (2001) Curr. Biol. , vol.11 , pp. 1847-1857
    • Rosenblatt, J.1    Raff, M.C.2    Cramer, L.P.3
  • 25
    • 34247401712 scopus 로고    scopus 로고
    • Bridge over troubled water: Milk fat globule epidermal growth factor 8 promotes human monocyte-derived macrophage clearance of non-blebbing phosphatidylserine-positive target cells
    • Witasp, E. et al. Bridge over troubled water: milk fat globule epidermal growth factor 8 promotes human monocyte-derived macrophage clearance of non-blebbing phosphatidylserine-positive target cells. Cell Death Differ. 14, 1063-1065 (2007).
    • (2007) Cell Death Differ. , vol.14 , pp. 1063-1065
    • Witasp, E.1
  • 26
    • 0030788683 scopus 로고    scopus 로고
    • The selective engulfment of apoptotic bodies by dendritic cells is mediated by the v-3 integrin and requires intracellular and extracellular calcium
    • Rubartelli, A., Poggi, A. & Zocchi, M. R. The selective engulfment of apoptotic bodies by dendritic cells is mediated by the v-3 integrin and requires intracellular and extracellular calcium. Eur. J. Immunol. 27, 1893-1900 (1997).
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1893-1900
    • Rubartelli, A.1    Poggi, A.2    Zocchi, M.R.3
  • 27
    • 84855504820 scopus 로고    scopus 로고
    • Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1
    • Berda-Haddad, Y. et al. Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1. Proc. Natl. Acad. Sci. USA 108, 20684-20689 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 20684-20689
    • Berda-Haddad, Y.1
  • 28
    • 77449127999 scopus 로고    scopus 로고
    • Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection
    • Zernecke, A. et al. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci. Signal. 2, ra81 (2009).
    • (2009) Sci. Signal. , vol.2 , pp. ra81
    • Zernecke, A.1
  • 29
    • 0035933154 scopus 로고    scopus 로고
    • Horizontal transfer of oncogenes by uptake of apoptotic bodies
    • Bergsmedh, A. et al. Horizontal transfer of oncogenes by uptake of apoptotic bodies. Proc. Natl. Acad. Sci. USA 98, 6407-6411 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6407-6411
    • Bergsmedh, A.1
  • 30
    • 77957942834 scopus 로고    scopus 로고
    • Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis
    • Chekeni, F. B. et al. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature 467, 863-867 (2010).
    • (2010) Nature , vol.467 , pp. 863-867
    • Chekeni, F.B.1
  • 31
    • 84926150693 scopus 로고    scopus 로고
    • HUHS1015 induces necroptosis and caspase-independent apoptosis of MKN28 human gastric cancer cells in association with AMID accumulation in the nucleus
    • Kaku, Y., Tsuchiya, A., Kanno, T. & Nishizaki, T. HUHS1015 induces necroptosis and caspase-independent apoptosis of MKN28 human gastric cancer cells in association with AMID accumulation in the nucleus. Anticancer Agents Med. Chem. 15, 242-247 (2015).
    • (2015) Anticancer Agents Med. Chem. , vol.15 , pp. 242-247
    • Kaku, Y.1    Tsuchiya, A.2    Kanno, T.3    Nishizaki, T.4
  • 32
    • 36549084087 scopus 로고    scopus 로고
    • Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins
    • Penuela, S. et al. Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. J. Cell Sci. 120, 3772-3783 (2007).
    • (2007) J. Cell Sci. , vol.120 , pp. 3772-3783
    • Penuela, S.1
  • 33
    • 12144288999 scopus 로고    scopus 로고
    • The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins
    • Baranova, A. et al. The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins. Genomics 83, 706-716 (2004).
    • (2004) Genomics , vol.83 , pp. 706-716
    • Baranova, A.1
  • 34
    • 84904089253 scopus 로고    scopus 로고
    • Pannexin channels and their links to human disease
    • Penuela, S., Harland, L., Simek, J. & Laird, D. W. Pannexin channels and their links to human disease. Biochem. J. 461, 371-381 (2014).
    • (2014) Biochem. J. , vol.461 , pp. 371-381
    • Penuela, S.1    Harland, L.2    Simek, J.3    Laird, D.W.4
  • 35
    • 0033590083 scopus 로고    scopus 로고
    • Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression
    • Fadeel, B. et al. Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression. Biochem. Biophys. Res. Commun. 266, 504-511 (1999).
    • (1999) Biochem. Biophys. Res. Commun. , vol.266 , pp. 504-511
    • Fadeel, B.1
  • 36
    • 0035846941 scopus 로고    scopus 로고
    • Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts
    • Fadok, V. A., de Cathelineau, A., Daleke, D. L., Henson, P. M. & Bratton, D. L. Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts. J. Biol. Chem. 276, 1071-1077 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 1071-1077
    • Fadok, V.A.1    De Cathelineau, A.2    Daleke, D.L.3    Henson, P.M.4    Bratton, D.L.5
  • 37
    • 79958045842 scopus 로고    scopus 로고
    • A new microparticle size calibration standard for use in measuring smaller microparticles using a new flow cytometer
    • Chandler, W. L., Yeung, W. & Tait, J. F. A new microparticle size calibration standard for use in measuring smaller microparticles using a new flow cytometer. J. Thromb. Haemost. 9, 1216-1224 (2011).
    • (2011) J. Thromb. Haemost. , vol.9 , pp. 1216-1224
    • Chandler, W.L.1    Yeung, W.2    Tait, J.F.3
  • 38
    • 84920973215 scopus 로고    scopus 로고
    • Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment
    • Rousseau, M. et al. Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment. PLoS ONE 10, e0116812 (2015).
    • (2015) PLoS ONE , vol.10 , pp. e0116812
    • Rousseau, M.1
  • 39
    • 84898413011 scopus 로고    scopus 로고
    • Phosphoinositide-mediated oligomerization of a defensin induces cell lysis
    • Poon, I. et al. Phosphoinositide-mediated oligomerization of a defensin induces cell lysis. Elife 3, e01808 (2014).
    • (2014) Elife , vol.3 , pp. e01808
    • Poon, I.1
  • 40
    • 84929441376 scopus 로고    scopus 로고
    • The tomato defensin TPP3 binds phosphatidylinositol (4,5)-bisphosphate via a conserved dimeric cationic grip conformation to mediate cell lysis
    • Baxter, A. A. et al. The tomato defensin TPP3 binds phosphatidylinositol (4,5)-bisphosphate via a conserved dimeric cationic grip conformation to mediate cell lysis. Mol. Cell. Biol. 35, 1964-1978 (2015).
    • (2015) Mol. Cell. Biol. , vol.35 , pp. 1964-1978
    • Baxter, A.A.1
  • 41
    • 77950587678 scopus 로고    scopus 로고
    • Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via Fc-RI on phagocytes
    • Poon, I. K., Hulett, M. D. & Parish, C. R. Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via Fc-RI on phagocytes. Blood 115, 2473-2482 (2010).
    • (2010) Blood , vol.115 , pp. 2473-2482
    • Poon, I.K.1    Hulett, M.D.2    Parish, C.R.3
  • 42
    • 77957115311 scopus 로고    scopus 로고
    • Histidine-rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake
    • Poon, I. K., Parish, C. R. & Hulett, M. D. Histidine-rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake. J. Leukoc. Biol. 88, 559-569 (2010).
    • (2010) J. Leukoc. Biol. , vol.88 , pp. 559-569
    • Poon, I.K.1    Parish, C.R.2    Hulett, M.D.3
  • 43
    • 0029866409 scopus 로고    scopus 로고
    • The use of 7-amino actinomycin D in identifying apoptosis: Simplicity of use and broad spectrum of application compared with other techniques
    • Philpott, N. J. et al. The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood 87, 2244-2251 (1996).
    • (1996) Blood , vol.87 , pp. 2244-2251
    • Philpott, N.J.1
  • 44
    • 84862017137 scopus 로고    scopus 로고
    • Dimerization of plant defensin NaD1 enhances its antifungal activity
    • Lay, F. T. et al. Dimerization of plant defensin NaD1 enhances its antifungal activity. J. Biol. Chem. 287, 19961-19972 (2012).
    • (2012) J. Biol. Chem. , vol.287 , pp. 19961-19972
    • Lay, F.T.1
  • 45
    • 84864488950 scopus 로고    scopus 로고
    • Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells
    • Dunai, Z. A. et al. Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells. PLoS ONE 7, e41945 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e41945
    • Dunai, Z.A.1
  • 46
    • 0042164446 scopus 로고    scopus 로고
    • Intravenously administered propidium iodide labels necrotic cells in the intact mouse brain after injury
    • Unal Cevik, I. & Dalkara, T. Intravenously administered propidium iodide labels necrotic cells in the intact mouse brain after injury. Cell Death Differ. 10, 928-929 (2003).
    • (2003) Cell Death Differ. , vol.10 , pp. 928-929
    • Unal Cevik, I.1    Dalkara, T.2
  • 47
    • 33749576792 scopus 로고    scopus 로고
    • Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
    • Fink, S. L. & Cookson, B. T. Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell. Microbiol. 8, 1812-1825 (2006).
    • (2006) Cell. Microbiol. , vol.8 , pp. 1812-1825
    • Fink, S.L.1    Cookson, B.T.2
  • 48
  • 49
    • 84873202976 scopus 로고    scopus 로고
    • Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila
    • Case, C. L. et al. Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila. Proc. Natl. Acad. Sci. USA 110, 1851-1856 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 1851-1856
    • Case, C.L.1
  • 50
    • 84923674191 scopus 로고    scopus 로고
    • RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
    • Lawlor, K. E. et al. RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat. Commun. 6, 6282 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 6282
    • Lawlor, K.E.1
  • 51
    • 84894326285 scopus 로고    scopus 로고
    • SHOX triggers the lysosomal pathway of apoptosis via oxidative stress
    • Hristov, G. et al. SHOX triggers the lysosomal pathway of apoptosis via oxidative stress. Hum. Mol. Genet. 23, 1619-1630 (2014).
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 1619-1630
    • Hristov, G.1
  • 52
    • 39749163470 scopus 로고    scopus 로고
    • Analysis of apoptosis by cytometry using TUNEL assay
    • Darzynkiewicz, Z., Galkowski, D. & Zhao, H. Analysis of apoptosis by cytometry using TUNEL assay. Methods 44, 250-254 (2008).
    • (2008) Methods , vol.44 , pp. 250-254
    • Darzynkiewicz, Z.1    Galkowski, D.2    Zhao, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.