U937 variant cells as a model of apoptosis without cell disintegration

Cellular and Molecular Biology Letters

Volumn 18, Issue 2, 2013, Pages 249-262

  Stasiłojć, Grzegorz ^a   Pinto, Sandra ^b   Wyszkowska, Roksana ^a   Wejda, Magda ^a,c   Słomińska, Ewa M ^a   Filipska, Martyna ^a   Koszałka, Patrycja ^a   Świerczyński, Julian ^a   O'Connor, Jose Enrique ^b   Bigda, Jacek Jerzy ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^c GHENT UNIVERSITY   (Belgium)

Author keywords

Apoptosis; Apoptotic bodies; Cell disintegration; U937 cells

Indexed keywords

CASPASE; CELL NUCLEUS DNA; CYTOCHROME C; ETOPOSIDE; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; APOPTOTIC BODY FORMATION; ARTICLE; CELL DISINTEGRATION; CELL MEMBRANE; CELL STIMULATION; CELL STRAIN U937; CELL STRAIN U937V; CELL STRUCTURE; CELLULAR PARAMETERS; CONTROLLED STUDY; CYTOTOXICITY; DNA DEGRADATION; DRUG EXPOSURE; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NUCLEOSOME; ZEIOSIS;

EID: 84877600259     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-013-0087-y     Document Type: Article

References (32)

1. Viorritto, I. C. B., Nikolov, N. P. and Siegel, R. M. Autoimmunity versus tolerance: can dying cells tip the balance? Clin. Immunol. 122 (2007) 125-134.
2. Gurumurthy, S., Vasudevan, K. M. and Rangnekar, V. M. Regulation of apoptosis in prostate cancer. Cancer Metastasis Rev. 20 (2001) 225-243.
3. Böhm, I. and Schild, H. Apoptosis: the complex scenario for a silent cell death. Mol. Imaging Biol. 5 (2003) 2-14.
4. Bras, M., Queenan, B. and Susin, S. A. Programmed cell death via mitochondria: different modes of dying. Biochemistry (Mosc)70 (2005) 231-239.
5. Krysko, D. V., VandenBerghe, T., D'Herde, K. and Vandenabeele, P. Apoptosis and necrosis: detection, discrimination and phagocytosis. Methods44 (2008) 205-221.
6. Oliveira, J. B. and Gupta, S. Disorders of apoptosis: mechanisms for autoimmunity in primary immunodeficiency diseases. J. Clin. Immunol. 28Suppl. 1, (2008) S20-S28.
7. Jana, N. R. NSAIDs and apoptosis. Cell Mol. Life Sci. 65 (2008) 1295-1301.
8. Festjens, N., VandenBerghe, T. and Vandenabeele, P. Necrosis, a wellorchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. Biochim. Biophys. Acta1757 (2006) 1371-1387.
9. Groninger, E., Meeuwsen-De Boer, G. J., De Graaf, S. S. N., Kamps, W. A. and De Bont, E. S. J. M. Vincristine induced apoptosis in acute lymphoblastic leukaemia cells: a mitochondrial controlled pathway regulated by reactive oxygen species? Int. J. Oncol. 21 (2002) 1339-1345.
10. Liao, P. and Lieu, C. Cell cycle specific induction of apoptosis and necrosis by paclitaxel in the leukemic U937 cells. Life Sci. 76 (2005) 1623-1639.
11. Cerella, C., Scherer, C., Cristofanon, S., Henry, E., Anwar, A., Busch, C., Montenarh, M., Dicato, M., Jacob, C. and Diederich, M. Cell cycle arrest in early mitosis and induction of caspase-dependent apoptosis in U937 cells by diallyltetrasulfide (Al2S4). Apoptosis14 (2009) 641-654.
12. van Hoof, C. and Goris, J. Phosphatases in apoptosis: to be or not to be, PP2A is in the heart of the question. Biochim. Biophys. Acta1640 (2003) 97-104.
13. Hail, N. J. Mitochondria: A novel target for the chemoprevention of cancer. Apoptosis10 (2005) 687-705.
14. Hori, T., Kondo, T., Tabuchi, Y., Takasaki, I., Zhao, Q., Kanamori, M., Yasuda, T. and Kimura, T. Molecular mechanism of apoptosis and gene expressions in human lymphoma U937 cells treated with anisomycin. Chem. Biol. Interact. 172 (2008) 125-140.
15. Ho, S., Chen, W., Chiu, H., Lai, C., Guo, H. and Wang, Y. Combination treatment with arsenic trioxide and irradiation enhances apoptotic effects in U937 cells through increased mitotic arrest and ROS generation. Chem. Biol. Interact. 179 (2009) 304-313.
16. Kaszubowska, L., Engelmann, H., Gotartowska, M., Iliszko, M. and Bigda, J. Identification of two U937 cell sublines exhibiting different patterns of response to tumour necrosis factor. Cytokine13 (2001) 365-370.
17. Shin, D. Y., Kim, G. Y., Li, W., Choi, B. T., Kim, N. D., Kang, H. S. and Choi, Y. H. Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells. Biomed. Pharmacother. 63 (2009) 86-94.
18. Python, F., Goebel, C. and Aeby, P. Assessment of the U937 cell line for the detection of contact allergens. Toxicol. Appl. Pharmacol. 220 (2007) 113-124.
19. Denecker, G., Vercammen, D., Declercq, W. and Vandenabeele, P. Apoptotic and necrotic cell death induced by death domain receptors. Cell Mol. Life Sci. 58 (2001) 356-370.
20. Takahashi, A., Masuda, A., Sun, M., Centonze, V. E. and Herman, B. Oxidative stress-induced apoptosis is associated with alterations in mitochondrial caspase activity and Bcl-2-dependent alterations in mitochondrial pH (pHm). Brain Res. Bull. 62 (2004) 497-504.
21. Smart, D. J., Halicka, H. D., Schmuck, G., Traganos, F., Darzynkiewicz, Z. and Williams, G. M. Assessment of DNA double-strand breaks and gammaH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone. Mutat. Res. 641 (2008) 43-47.
22. Sundstrom, C. and Nilsson, K. Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int. J. Cancer17 (1976) 565-577.
23. Ndozangue-Touriguine, O., Hamelin, J. and Bréard, J. Cytoskeleton and apoptosis. Biochem. Pharmacol. 76 (2008) 11-18.
24. Izyumov, D. S., Avetisyan, A. V., Pletjushkina, O. Y., Sakharov, D. V., Wirtz, K. W., Chernyak, B. V. and Skulachev, V. P. "Wages of fear": transient threefold decrease in intracellular ATP level imposes apoptosis. Biochim. Biophys. Acta1658 (2004) 141-147.
25. Orlando, K. A., Stone, N. L. and Pittman, R. N. Rho kinase regulates fragmentation and phagocytosis of apoptotic cells. Exp. Cell Res. 312 (2006) 5-15.
26. Salvioli, S., Barbi, C., Dobrucki, J., Moretti, L., Pinti, M., Pedrazzi, J., Pazienza, T. L., Bobyleva, V., Franceschi, C. and Cossarizza, A. Opposite role of changes in mitochondrial membrane potential in different apoptotic processes. FEBS Lett. 469 (2000) 186-190.
27. Chung, Y. M., Bae, Y. S. and Lee, S. Y. Molecular ordering of ROS production, mitochondrial changes, and caspase activation during sodium salicylate-induced apoptosis. Free Radic. Biol. Med. 34 (2003) 434-442.
28. Watabe, M. and Nakaki, T. ATP depletion does not account for apoptosis induced by inhibition of mitochondrial electron transport chain in human dopaminergic cells. Neuropharmacology52 (2007) 536-541.
29. Krysko, D. V., D'Herde, K. and Vandenabeele, P. Clearance of apoptotic and necrotic cells and its immunological consequences. Apoptosis11 (2006) 1709-1726.
30. Raina, A. K., Hochman, A., Zhu, X., Rottkamp, C. A., Nunomura, A., Siedlak, S. L., Boux, H., Castellani, R. J., Perry, G. and Smith, M. A. Abortive apoptosis in Alzheimer's disease. Acta Neuropathol. 101 (2001) 305-310.
31. Schrijvers, D. M., Martinet, W., De Meyer, G. R. Y., Andries, L., Herman, A. G. and Kockx, M. M. Flow cytometric evaluation of a model for phagocytosis of cells undergoing apoptosis. J. Immunol. Methods287 (2004) 101-108.
32. Petrovski, G., Zahuczky, G., Katona, K., Vereb, G., Martinet, W., Nemes, Z., Bursch, W. and Fésüs, L. Clearance of dying autophagic cells of different origin by professional and non-professional phagocytes. Cell Death Differ. 14 (2007) 1117-1128.