Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

eLife

Volumn 2014, Issue 3, 2014, Pages

  Poon, Ivan K H ^a   Baxter, Amy A ^a   Lay, Fung T ^a   Mills, Grant D ^a   Adda, Christopher G ^a   Payne, Jennifer A E ^a   Phan, Thanh Kha ^a   Ryan, Gemma F ^a   White, Julie A ^a   Veneer, Prem K ^a   van der Weerden, Nicole L ^a   Anderson, Marilyn A ^a   Kvansakul, Marc ^a   Hulett, Mark D ^a  

^a LA TROBE UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DEFENSIN; DEFENSIN NAD1; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; LACTATE DEHYDROGENASE; LIPOSOME; OLIGOMER; PHOSPHATIDYLINOSITOL 4, 5 BISPHOSPHATE; UNCLASSIFIED DRUG; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PROTEIN BINDING;

ARTICLE; ASSAY; BIOLUMINESCENCE; CELL KILLING; CELL MEMBRANE PERMEABILITY; CELL PERMEABILIZATION; CELL VIABILITY ASSAY; COMPLEX FORMATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CROSS LINKING; CRYSTAL STRUCTURE; CYTOLYSIS; DRUG BINDING; DRUG LABELING; DRUG PURIFICATION; FUNGAL CELL; FUNGUS GROWTH; GROWTH INHIBITION; HUMAN; HUMAN CELL; MTT ASSAY; NONHUMAN; OLIGOMERIZATION; PICHIA PASTORIS; PROPIDIUM IODIDE ASSAY; PULL DOWN ASSAY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL; X RAY CRYSTALLOGRAPHY; CELL DEATH; CHEMISTRY; DRUG EFFECTS; EPITHELIUM CELL; FUSARIUM; GENETICS; HELA CELL LINE; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL VIABILITY; PHYSIOLOGY; PROTEIN MULTIMERIZATION; SITE DIRECTED MUTAGENESIS; TOBACCO;

CELL DEATH; CRYSTALLOGRAPHY, X-RAY; DEFENSINS; EPITHELIAL CELLS; FUSARIUM; HELA CELLS; HUMANS; MICROBIAL VIABILITY; MUTAGENESIS, SITE-DIRECTED; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN BINDING; PROTEIN MULTIMERIZATION; TOBACCO;

EID: 84898413011     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.01808     Document Type: Article

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