Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages

Journal of Immunology

Volumn 169, Issue 8, 2002, Pages 4531-4541

  Li, Ning ^a   Wang, Meiying ^a   Oberley, Terry D ^a   Sempf, Joan M ^a   Nel, Andre E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; DIESEL FUEL; GLUTATHIONE; HEME OXYGENASE 1; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; BRONCHUS MUCOSA; CELL DEATH; CELL PROTECTION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; EXHAUST GAS; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0037108605     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.8.4531     Document Type: Article

References (64)

1. Pope, C. A., M. J. Thun, M. M. Namboodiri, D. W. Dockery, J. S. Evans, F. E. Speizer, and C. W. Heath. Jr. 1995. Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults. Am. J. Respir. Crit. Care Med. 151:669.
2. Dockery, D. W., C. A. Pope, X. Xu, J. D. Spengler, J. H. Ware, M. E. Fay, B. G. Ferris, and F. E. Speizer. 1993. An association between air pollution and mortality in six U.S. cities. N. Engl. J. Med. 29:1753.
3. Pope, C. A., and D. W. Dockery. 1998. Epidemiology of particle effects. In Air Pollution and Health. S. T. Holgate, J. M. Samet, H. S. Koren, and R. L. Maynard. eds. Academic Press. London, p. 673.
4. Pope, C. A. 1999. Mortality and air pollution: associations persist with continued advances in research methodology. Environ. Health Perspect. 107:613.
5. Pope, C. A., D. W. Dockery, R. E. Kanner, G. M. Villegas, and J. Schwartz. 1999. Oxygen saturation, pulse rate, and particulate air pollution: a daily time-series panel study. Am. J. Respir. Crit. Care Med. 159:365.
6. National Research Council. 1998. Research Priorities for Airborne Particulate Matter. I. Immediate Priorities and a Long-Range Research Portfolio. National Academy of Science, Washington, D.C.
7. Nel, A. E., D. Diaz-Sanchez, and N. Li. 2001. The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress. Curr. Opin. Pulmonary Med. 7:20.
8. Nel, A. E., D. Diaz-Sanchez, D. Ng, T. Hiura, and A. Saxon. 1998. Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system. J. Allergy Clin. Immunol. 102:539.
9. Diaz-Sanchez, D., M. Jyrala, D. Ng, A. Nel, and A. Saxon. 2000. In vivo nasal challenge with diesel exhaust particles enhances expression of the CC chemokines RANTES, MIP-1α, and MCP-3 in humans. Clin. Immunol. 97:140.
10. Sagai, M., H. Saito, T. Ichinose, M. Kodama, and Y. Morri. 1993. Biological effects of diesel exhaust particles. In vitro production of superoxide and in vivo toxicity in mouse. Free Radical Biol. Med. 14:37.
11. Li, N., M. I. Venkatesan, A. Miguel, R. Kaplan, C. Gujuluva, J. Alam, and A. E. Nel. 2000. Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidant-responsive element. J. Immunol. 165:3393.
12. Schuetzle, D., F. S. Lee, and J. J. Prater. 1981. The identification of polynuclear aromatic hydrocarbon (PAH) derivatives in mutagenic fractions of diesel particulate extracts. Int. J. Enriron. Anal Chem. 9:93.
13. Anderson, H., E. Lindqvist, R. Westerholm, K. Gragg, J. Almen, and L. Olson. 1998. Neurotoxic effects of fractionated diesel exhaust following microinjections in rat hippocampus and striatum. Environ. Res. 76:41.
14. Li, H., C. D. Banner, G. G. Mason, R. N. Westerholm, and J. J. Rafter. 1996. Determination of polycyclic aromatic compounds and dioxan receptor ligands present in diesel exhaust particulate extracts. Atmos. Environ. 30:3537.
15. Kumagai, Y., T. Arimoto, M. Shinyyashiki, N. Shimojo, Y. Nakai, T. Yoshikawa, and M. Sagai. 1997. Generation of reactive oxygen species during interaction of diesel exhaust particle compounds with NADPH-cytochrome P450 reductase and involvement of the bioactivation in the DNA damage. Free Radical Biol. Med. 22:479.
16. Whitekus, M. J., N. Li, M. Zhang, M. Wang, M. A. Horwitz, S. K. Nelson, L. D. Horwitz, N. Brechun, D. Diaz-Sanchez, and A. Nel. 2002. Thiol antioxidant inhibit the adjuvant effects of aerosolized diesel exhaust particles in a murine model for ovalbumin sensitization. J. Immunol. 168:2560.
17. Hiura, T. S., M. P. Kaszubowski, N. Li. and A. E. Nel. 1999. Chemicals in diesel exhaust particles generate reactive oxygen radicals and apoptosis in macrophages. J. Immunol. 163:5582.
18. Hiura, T. S., N. Li, R. Kaplan, M. Horwitz, J. Seagrave, and A. E. Nel. 2000. The role of a mitochondrial pathway in the induction of apoptosis by chemicals extracted from diesel exhaust particles. J. Immunol. 165:2703.
19. Squadrio, G. L., R. Cueto, B. Dellinger, and W. A. Pryor. 2001. Quinoid redox cycling as a mechanism for sustained free radical generation by inhaled airborne particulate matter. Free Radical Biol. Med. 31:1132.
20. MacNee, W., and K. Donaldson. 1998. Particulate air pollution: injurious and protective mechanisms in the lung. In: Air Pollution and Health. Vol. 30. S. T. Holgate, J. M. Samet, H. S. Koren, and R. L. Maynard. eds. Academic Press, London, pp. 653-672.
21. Alsberg, T., U. Stenberg, R. Westerholm, M. Strandell, U. Rannug, A. Sundvall, L. Romert, U. Bemson, B. Perterson, R. Toftgard, et al. 1985. Chemical and biological characterization of organic material from gasoline exhaust particles. Environ. Sci. Technol. 19:43.
22. Becker, S., J. M. Soukup, M. I. Gilmour, and R. B. Devlin. 1996. Stimulation of human and rat alveolar macrophages by urban air particulates: effects on oxidant radical generation and cytokine production. Toxicol. Appl. Pharmacol. 141:637.
23. Goldsmith, C., C. Frevert, A. Imrich, C. Sioutas, and L. Kobzik. 1997. Alveolar macrophage interaction with air pollution particulates. Environ. Health Perspect. 105:1191.
24. Li, N., S. Kim, M. Wang, J. Froines, C. Sioutas, and A. E. Nel. 2001. Evidence for the use of a stratified oxidative stress model to study the biological effects of ambient concentrated and diesel exhaust particulate matter. Inhalation Toxicol. 14:101.
25. Martin, L. D., T. M. Krunkovsky, J. A. Dye, B. M. Fischer, N. F. Jiang, L. G. Rochelle, N. J. Akley, K. L. Dreher, and K. B. Adler. 1997. The role of reactive oxygen and nitrogen species in the response of airway epithelium to particulates. J. Environ. Health Perspect. 105:1301.
26. Bayram, H., J. L. Devalia, O. A. Khair, M. Muntasir, M. B. Abdelazia, R. J. Sapsford, M. Sagai, and R. J. Davies. 1998. Comparison of ciliary activity and inflammatory mediator release from bronchial epithelial cells of nonatopic nonasthmatic subjects and atopic asthmatic patients the effects of diesel exhaust particles in vitro. J. Allergy Clin. Immunol. 102:771.
27. Ohtoshi, T., H. Takizawa, H. Okazaki, S. Kawasaki, N. Takeuchi, K. Ohta, and K. Ito. 1998. Diesel exhaust particles stimulate human airway epithelial cells to produce cytokines relevant to airway inflammation in vitro. J. Allergy Clin. Inmunol. 101:778.
28. Takizawa, H., T. Ohtoshi, S. Kawasaki, T. Kohyama, M. Desaki, T. Kasama, K. Kobayashi, K. Nakahara, K. Yamamoto, K. Matsushima, et al. 1999. Diesel exhaust particles induce NF-KB activation in human bronchial epithelial cells in vitro: importance in cytokine transcription. J. Clin. Allergy Immunol. 162:4705.
29. Holgate, S. T., P. M. Lackie, D. E., Davies, W. R. Roche, and A. F. Walls. 1999. The bronchial epithelium as a key regulator of airway inflammation and remodeling in asthma. Clin. Exp. Allergy 29:90.
30. Boland, S., V. Bonvallot, T. Fournier, A. Baeza-Squiban, M. Aubier, and F. Marano. 2000. Mechanisms of GM-CSF increase by diesel exhaust particles in human airway epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 278:L25.
31. Steerenberg, P. A., J. A. Zonnenberg, J. A. Dormans, P. N. Joon, I. M. Wouters, L. van Bree, P. T. Scheepers, and H. Van Loveren. 1998. Diesel exhaust particles induced release of interleukin 6 and 8 by (primed) human bronchial epithelial cells (BEAS 2B) in vitro. Exp. Lung Res. 24:85.
32. Bayram, H., J. L. Devalia, R. J. Sapsford, T. Ohtoshi, Y. Miyabara, M. Sagai, and R. J. Davies. 1998. The effect of diesel exhaust particles on cell function and release of inflammatory mediators from human bronchial epithelial cells in vitro. Am. J. Respir. Cell Mol. Biol. 18:441.
33. Boland. S., A. Baeza-Squiban, T. Fournier, O. Houcine, M. C. Gendron, M. Chévrier, G. Jouvenot, A. Coste, M. Aubier, and F. Marano. 1999. Diesel exhaust particles are taken up by human airway epithelial cells in vitro and alter cytokine production. Am. J. Physiol. 276:L604.
34. Devalia, J. L., H. Bayram, C. Rusznak, M. Calderón, R. J. Sapsford, M. A. Abdelaziz, J. Wang, and R. J., Davies. 1997. Mechanisms of pollution-induced airway disease: in vitro studies in the upper and lower airways. Allergy 52(Suppl. 38):45.
35. Wagner, J. G., S. J. Van Dtken, J. A. Hotchkiss, and J. R. Harkema. 2001. Endotoxin enhancement of ozone-induced mucous cell metaplasia is neutrophil-dependent in rat nasal epithelium. Toxicol. Sci. 60:338.
36. Kutty, R. K., G. Kutty, C. N. Nagineni, Hooks, J. J., G. J. Chader, and B. Wiggert. 1994. RT-PCR assay for heme oxygenase-1 and heme oxygenase-2: a sensitive method to estimate cellular oxidative damage. Ann. NY Acad. Sci. 738:427.
37. Tietze, F. 1969. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27:502.
38. Griffith, O. W. 1980. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106:207.
39. Bump, E. A., Y. C. Taylor. and J. M. Brown. 1983. Role of glutathione in the hypoxic cell cytotoxicity of misonidazole. Cancer Res. 43:997.
40. Yang, A. H., J. Gould-Kosta, and T. D. Oberley. 1987. In vitro growth and differentiation of human tubular cells on basement membrane substrate. In Vitro Cell. Dev. Biol. 23:34.
41. Mukaida, N., Y. Mahe, and K. Matsushima. 1990. Cooperative interaction of nuclear factor-κB- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines. J. Biol. Chem. 265:21128.
42. Mori, N., N. Mukaida, D. W. Ballard, K. Matsushima, and N. Yamamoto. 1998. Human T-cell leukemia virus type I tax transactivates human interleukin 8 gene through acting concurrently on AP-1 and nuclear factor-κB-like sites. Cancer Res. 58:3993.
43. Coppola, S., and L. Ghibelli. 2000. GSH extrusion and the mitochondrial pathway of apoptotic signaling. Biochem. Soc. Trans. 28:56-61.
44. Rahman, I., and W. MacNee. 2000. Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radical Biol. Med. 28:1405.
45. Rahman, I., and W. MacNee. 2000. Oxidative stress and regulation of glutathione in lung inflammation. Eur. Respir. J. 16:534.
46. Rahman, I. 1999. Inflammation and the regulation of glutathione level in lung epithelial cells. Antioxid. Redox. Signalling 1:425.
47. Prestera, T., P. Talalay, J. Alam, Y. I. Ahn, P. J. Lee, and A. M. Choi. 1995. Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE). Mol. Med. 1:827.
48. Maines, M. D. 1997. The heme oxygenase system: a regulator of second messenger gases. Annu. Rev. Pharmacol. Toxicol. 37:517.
49. Nightingale, J. A., R. Maggs, P. Cullinan, L. E. Donnellely, D. F. Rogers, R. Kinnersley, K. F. Chung, P. J. Barnes, M. Ashmore, and A. Newman-Taylor. 2000. Airway inflammation after controlled exposure to diesel exhaust particulates. Am. J. Respir. Crit. Care Med. 162:161.
50. Alam, J., D. Stewart, C. Touchard, S. Boinapally, A. M. Choi, and J. L. Cook. 1999. Nrf2, a cap'n'collar transcription factor, regulates induction of the heme oxygenase-1 gene. J. Biol. Chem. 274:26071.
51. Chan, K., and Y. W. Kan. 1999. Nrf2 is essential for protection against acute pulmonary injury in mice. Proc. Natl. Acad. Sci. USA 96:12731.
52. Sen, C., and L. Packer. 1996. Antioxidant and redox regulation of gene transcription. FASEB J. 10:709.
53. Lander, M. 1997. An essential role for free radicals and derived species in signal transduction. FASEB J. 11:118.
54. Segura-Aguilar, J., D. Metodiewa, and C. J. Welch. 1998. Metabolic activation of dopamine o-quinone to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects. Biochim. Biophys. Acta 1381:1.
55. 2-terminal kinase by benzo(a)pyrene. Cancer Res. 58:2102.
56. Cai, J., and D. P. Jones. 1998. Superoxide in apoptosis: mitochondrial generation triggered by cytochrome C loss. J. Biol. Chem. 273:11401.
57. Kroemer, G., B. Dallaporta, and M. Resche-Rigon. 1998. The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol. 60:619.
58. Zoratti. M., and I. Szabo. 1995. The mitochondrial permeability transition. Biochim. Biophys. Acta 1241:139.
59. Fernández-checa, J. C., C, Garcia-Ruiz, A. Colell, A. Morales, M. Mari, M. Miranda, and E. Ardite. 1998. Oxidative stress: role of mitochondria and protection by glutathione. Biofactors 8:7.
60. Izzotti, A., A. Camoirana, F. D'Agostini, S. Sciacca, F. De Naro Papa, C. F. Cesarone, and S. De Flora. 1996. Biomarker alterations produced in rat lung by intratracheal instillation of air particulate extracts and chemoprevention with oral N-acetyl-cysteine. Cancer Res. 56:1533.
61. Goldsmith, C. A., A. Imrich, H. Danaee, Y. Y. Ning, and L. Kobzik. 1998. Analysis of air pollution particulate-mediated oxidant stress in alveolar macrophages. J. Toxicol. Environ. Health A 54:529.
62. Jaiswal, A. K. 1994. Commentary: antioxidant response element. Biochem. Pharmacol. 48:439.
63. Choi, A. M. K., and J. Alam. 1996. Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am. J. Respir. Cell Mol. Biol. 15:9.
64. Yamada, N., M. Yamaya, S. Okinaga, K. Nakayama, K. Sekizawa, S. Shibahara, and H. Sasaki. 2000. Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am. J. Hum. Genet. 66:187.