Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cells

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Kozako, Tomohiro ^a   Suzuki, Takayoshi ^b   Yoshimitsu, Makoto ^c,d   Uchida, Yuichiro ^a   Kuroki, Ayako ^d   Aikawa, Akiyoshi ^a   Honda, Shin Ichiro ^a   Arima, Naomichi ^c,d   Soeda, Shinji ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c KAGOSHIMA UNIVERSITY HOSPITAL   (Japan)

^d KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; HISTONE; HISTONE DEACETYLASE INHIBITOR; LIPOCORTIN 5; REACTIVE OXYGEN METABOLITE; SIRTUIN 1;

ACETYLATION; ANTAGONISTS AND INHIBITORS; APOPTOSIS; AUTOPHAGY; CELL DEATH; CELL SURVIVAL; DRUG EFFECTS; HUMAN; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MONONUCLEAR CELL; T CELL LEUKEMIA; TUMOR CELL CULTURE; TUMOR CELL LINE;

ACETYLATION; ANNEXIN A5; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CASPASES; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; HISTONE DEACETYLASE INHIBITORS; HISTONES; HUMANS; LEUKEMIA-LYMPHOMA, ADULT T-CELL; LEUKOCYTES, MONONUCLEAR; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES; SIRTUIN 1; TUMOR CELLS, CULTURED;

EID: 84934969509     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep11345     Document Type: Article

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