-
1
-
-
3042801308
-
SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
-
Cao, R. and Zhang, Y. (2004) SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex Mol. Cell 15, 57-67 10.1016/j.molcel.2004.06.020
-
(2004)
Mol. Cell
, vol.15
, pp. 57-67
-
-
Cao, R.1
Zhang, Y.2
-
2
-
-
84937397052
-
A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models
-
Chan-Penebre, E., Kuplast, K. G., Majer, C. R., Boriack-Sjodin, P. A., Wigle, T. J., Johnston, L. D., Rioux, N., Munchhof, M. J., Jin, L., Jacques, S. L., West, K. A., Lingaraj, T., Stickland, K., Ribich, S. A., Raimondi, A., Scott, M. P., Waters, N. J., Pollock, R. M., Smith, J. J., Barbash, O., Pappalardi, M., Ho, T. F., Nurse, K., Oza, K. P., Gallagher, K. T., Kruger, R., Moyer, M. P., Copeland, R. A., Chesworth, R., and Duncan, K. W. (2015) A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models Nat. Chem. Biol. 11, 432-437 10.1038/nchembio.1810
-
(2015)
Nat. Chem. Biol.
, vol.11
, pp. 432-437
-
-
Chan-Penebre, E.1
Kuplast, K.G.2
Majer, C.R.3
Boriack-Sjodin, P.A.4
Wigle, T.J.5
Johnston, L.D.6
Rioux, N.7
Munchhof, M.J.8
Jin, L.9
Jacques, S.L.10
West, K.A.11
Lingaraj, T.12
Stickland, K.13
Ribich, S.A.14
Raimondi, A.15
Scott, M.P.16
Waters, N.J.17
Pollock, R.M.18
Smith, J.J.19
Barbash, O.20
Pappalardi, M.21
Ho, T.F.22
Nurse, K.23
Oza, K.P.24
Gallagher, K.T.25
Kruger, R.26
Moyer, M.P.27
Copeland, R.A.28
Chesworth, R.29
Duncan, K.W.30
more..
-
3
-
-
8144230178
-
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
-
Pasini, D., Bracken, A. P., Jensen, M. R., Lazzerini Denchi, E., and Helin, K. (2004) Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity EMBO J. 23, 4061-4071 10.1038/sj.emboj.7600402
-
(2004)
EMBO J.
, vol.23
, pp. 4061-4071
-
-
Pasini, D.1
Bracken, A.P.2
Jensen, M.R.3
Lazzerini Denchi, E.4
Helin, K.5
-
4
-
-
84928491983
-
Role of PRC2-associated factors in stem cells and disease
-
Vizan, P., Beringer, M., Ballare, C., and Di Croce, L. (2015) Role of PRC2-associated factors in stem cells and disease FEBS J. 282, 1723-1735 10.1111/febs.13083
-
(2015)
FEBS J.
, vol.282
, pp. 1723-1735
-
-
Vizan, P.1
Beringer, M.2
Ballare, C.3
Di Croce, L.4
-
5
-
-
55549103314
-
A model for transmission of the H3K27me3 epigenetic mark
-
Hansen, K. H., Bracken, A. P., Pasini, D., Dietrich, N., Gehani, S. S., Monrad, A., Rappsilber, J., Lerdrup, M., and Helin, K. (2008) A model for transmission of the H3K27me3 epigenetic mark Nat. Cell Biol. 10, 1291-1300 10.1038/ncb1787
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1291-1300
-
-
Hansen, K.H.1
Bracken, A.P.2
Pasini, D.3
Dietrich, N.4
Gehani, S.S.5
Monrad, A.6
Rappsilber, J.7
Lerdrup, M.8
Helin, K.9
-
6
-
-
70349952171
-
Role of the polycomb protein EED in the propagation of repressive histone marks
-
Margueron, R., Justin, N., Ohno, K., Sharpe, M. L., Son, J., Drury, W. J., III, Voigt, P., Martin, S. R., Taylor, W. R., De Marco, V., Pirrotta, V., Reinberg, D., and Gamblin, S. J. (2009) Role of the polycomb protein EED in the propagation of repressive histone marks Nature 461, 762-767 10.1038/nature08398
-
(2009)
Nature
, vol.461
, pp. 762-767
-
-
Margueron, R.1
Justin, N.2
Ohno, K.3
Sharpe, M.L.4
Son, J.5
Drury, W.J.6
Voigt, P.7
Martin, S.R.8
Taylor, W.R.9
De Marco, V.10
Pirrotta, V.11
Reinberg, D.12
Gamblin, S.J.13
-
7
-
-
78650613168
-
Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2)
-
Xu, C., Bian, C., Yang, W., Galka, M., Ouyang, H., Chen, C., Qiu, W., Liu, H., Jones, A. E., MacKenzie, F., Pan, P., Li, S. S., Wang, H., and Min, J. (2010) Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2) Proc. Natl. Acad. Sci. U. S. A. 107, 19266-19271 10.1073/pnas.1008937107
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 19266-19271
-
-
Xu, C.1
Bian, C.2
Yang, W.3
Galka, M.4
Ouyang, H.5
Chen, C.6
Qiu, W.7
Liu, H.8
Jones, A.E.9
MacKenzie, F.10
Pan, P.11
Li, S.S.12
Wang, H.13
Min, J.14
-
8
-
-
84924062795
-
Jarid2Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation
-
Sanulli, S., Justin, N., Teissandier, A., Ancelin, K., Portoso, M., Caron, M., Michaud, A., Lombard, B., da Rocha, S. T., Offer, J., Loew, D., Servant, N., Wassef, M., Burlina, F., Gamblin, S. J., Heard, E., and Margueron, R. (2015) Jarid2Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation Mol. Cell 57, 769-783 10.1016/j.molcel.2014.12.020
-
(2015)
Mol. Cell
, vol.57
, pp. 769-783
-
-
Sanulli, S.1
Justin, N.2
Teissandier, A.3
Ancelin, K.4
Portoso, M.5
Caron, M.6
Michaud, A.7
Lombard, B.8
Da Rocha, S.T.9
Offer, J.10
Loew, D.11
Servant, N.12
Wassef, M.13
Burlina, F.14
Gamblin, S.J.15
Heard, E.16
Margueron, R.17
-
9
-
-
84881497258
-
Molecular architecture of human polycomb repressive complex 2
-
Ciferri, C., Lander, G. C., Maiolica, A., Herzog, F., Aebersold, R., and Nogales, E. (2012) Molecular architecture of human polycomb repressive complex 2 eLife 1, e00005 10.7554/eLife.00005
-
(2012)
ELife
, vol.1
-
-
Ciferri, C.1
Lander, G.C.2
Maiolica, A.3
Herzog, F.4
Aebersold, R.5
Nogales, E.6
-
10
-
-
84945186017
-
Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2
-
Jiao, L. and Liu, X. (2015) Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2 Science 350, aac4383 10.1126/science.aac4383
-
(2015)
Science
, vol.350
, pp. aac4383
-
-
Jiao, L.1
Liu, X.2
-
11
-
-
79955494277
-
Histone methylation by PRC2 is inhibited by active chromatin marks
-
Schmitges, F. W., Prusty, A. B., Faty, M., Stutzer, A., Lingaraju, G. M., Aiwazian, J., Sack, R., Hess, D., Li, L., Zhou, S., Bunker, R. D., Wirth, U., Bouwmeester, T., Bauer, A., Ly-Hartig, N., Zhao, K., Chan, H., Gu, J., Gut, H., Fischle, W., Muller, J., and Thoma, N. H. (2011) Histone methylation by PRC2 is inhibited by active chromatin marks Mol. Cell 42, 330-341 10.1016/j.molcel.2011.03.025
-
(2011)
Mol. Cell
, vol.42
, pp. 330-341
-
-
Schmitges, F.W.1
Prusty, A.B.2
Faty, M.3
Stutzer, A.4
Lingaraju, G.M.5
Aiwazian, J.6
Sack, R.7
Hess, D.8
Li, L.9
Zhou, S.10
Bunker, R.D.11
Wirth, U.12
Bouwmeester, T.13
Bauer, A.14
Ly-Hartig, N.15
Zhao, K.16
Chan, H.17
Gu, J.18
Gut, H.19
Fischle, W.20
Muller, J.21
Thoma, N.H.22
more..
-
12
-
-
79960367903
-
Chemogenetic analysis of human protein methyltransferases
-
Richon, V. M., Johnston, D., Sneeringer, C. J., Jin, L., Majer, C. R., Elliston, K., Jerva, L. F., Scott, M. P., and Copeland, R. A. (2011) Chemogenetic analysis of human protein methyltransferases Chem. Biol. Drug Des. 78, 199-210 10.1111/j.1747-0285.2011.01135.x
-
(2011)
Chem. Biol. Drug Des.
, vol.78
, pp. 199-210
-
-
Richon, V.M.1
Johnston, D.2
Sneeringer, C.J.3
Jin, L.4
Majer, C.R.5
Elliston, K.6
Jerva, L.F.7
Scott, M.P.8
Copeland, R.A.9
-
13
-
-
69949148388
-
Protein methyltransferases as a target class for drug discovery
-
Copeland, R. A., Solomon, M. E., and Richon, V. M. (2009) Protein methyltransferases as a target class for drug discovery Nat. Rev. Drug Discovery 8, 724-732 10.1038/nrd2974
-
(2009)
Nat. Rev. Drug Discovery
, vol.8
, pp. 724-732
-
-
Copeland, R.A.1
Solomon, M.E.2
Richon, V.M.3
-
14
-
-
55949132133
-
Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms
-
Margueron, R., Li, G., Sarma, K., Blais, A., Zavadil, J., Woodcock, C. L., Dynlacht, B. D., and Reinberg, D. (2008) Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms Mol. Cell 32, 503-518 10.1016/j.molcel.2008.11.004
-
(2008)
Mol. Cell
, vol.32
, pp. 503-518
-
-
Margueron, R.1
Li, G.2
Sarma, K.3
Blais, A.4
Zavadil, J.5
Woodcock, C.L.6
Dynlacht, B.D.7
Reinberg, D.8
-
15
-
-
78650454078
-
Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
-
Sneeringer, C. J., Scott, M. P., Kuntz, K. W., Knutson, S. K., Pollock, R. M., Richon, V. M., and Copeland, R. A. (2010) Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas Proc. Natl. Acad. Sci. U. S. A. 107, 20980-20985 10.1073/pnas.1012525107
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 20980-20985
-
-
Sneeringer, C.J.1
Scott, M.P.2
Kuntz, K.W.3
Knutson, S.K.4
Pollock, R.M.5
Richon, V.M.6
Copeland, R.A.7
-
16
-
-
84914177439
-
Reaction coupling between wild-type and disease-associated mutant EZH2
-
Swalm, B. M., Knutson, S. K., Warholic, N. M., Jin, L., Kuntz, K. W., Keilhack, H., Smith, J. J., Pollock, R. M., Moyer, M. P., Scott, M. P., Copeland, R. A., and Wigle, T. J. (2014) Reaction coupling between wild-type and disease-associated mutant EZH2 ACS Chem. Biol. 9, 2459-2464 10.1021/cb500548b
-
(2014)
ACS Chem. Biol.
, vol.9
, pp. 2459-2464
-
-
Swalm, B.M.1
Knutson, S.K.2
Warholic, N.M.3
Jin, L.4
Kuntz, K.W.5
Keilhack, H.6
Smith, J.J.7
Pollock, R.M.8
Moyer, M.P.9
Scott, M.P.10
Copeland, R.A.11
Wigle, T.J.12
-
17
-
-
84888409855
-
The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination
-
Kogure, M., Takawa, M., Saloura, V., Sone, K., Piao, L., Ueda, K., Ibrahim, R., Tsunoda, T., Sugiyama, M., Atomi, Y., Nakamura, Y., and Hamamoto, R. (2013) The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination Neoplasia 15, 1251-1261 10.1593/neo.131436
-
(2013)
Neoplasia
, vol.15
, pp. 1251-1261
-
-
Kogure, M.1
Takawa, M.2
Saloura, V.3
Sone, K.4
Piao, L.5
Ueda, K.6
Ibrahim, R.7
Tsunoda, T.8
Sugiyama, M.9
Atomi, Y.10
Nakamura, Y.11
Hamamoto, R.12
-
18
-
-
84928570108
-
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin
-
Gunawan, M., Venkatesan, N., Loh, J. T., Wong, J. F., Berger, H., Neo, W. H., Li, L. Y., La Win, M. K., Yau, Y. H., Guo, T., See, P. C., Yamazaki, S., Chin, K. C., Gingras, A. R., Shochat, S. G., Ng, L. G., Sze, S. K., Ginhoux, F., and Su, I. H. (2015) The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin Nat. Immunol. 16, 505-516 10.1038/ni.3125
-
(2015)
Nat. Immunol.
, vol.16
, pp. 505-516
-
-
Gunawan, M.1
Venkatesan, N.2
Loh, J.T.3
Wong, J.F.4
Berger, H.5
Neo, W.H.6
Li, L.Y.7
La Win, M.K.8
Yau, Y.H.9
Guo, T.10
See, P.C.11
Yamazaki, S.12
Chin, K.C.13
Gingras, A.R.14
Shochat, S.G.15
Ng, L.G.16
Sze, S.K.17
Ginhoux, F.18
Su, I.H.19
-
19
-
-
84961290058
-
STAT3-driven transcription depends upon the dimethylation of K49 by EZH2
-
Dasgupta, M., Dermawan, J. K., Willard, B., and Stark, G. R. (2015) STAT3-driven transcription depends upon the dimethylation of K49 by EZH2 Proc. Natl. Acad. Sci. U. S. A. 112, 3985-3990 10.1073/pnas.1503152112
-
(2015)
Proc. Natl. Acad. Sci. U. S. A.
, vol.112
, pp. 3985-3990
-
-
Dasgupta, M.1
Dermawan, J.K.2
Willard, B.3
Stark, G.R.4
-
20
-
-
17644410781
-
Nucleosome binding and histone methyltransferase activity of Drosophila PRC2
-
Nekrasov, M., Wild, B., and Muller, J. (2005) Nucleosome binding and histone methyltransferase activity of Drosophila PRC2 EMBO Rep. 6, 348-353 10.1038/sj.embor.7400376
-
(2005)
EMBO Rep.
, vol.6
, pp. 348-353
-
-
Nekrasov, M.1
Wild, B.2
Muller, J.3
-
21
-
-
33746407708
-
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
-
Schoeftner, S., Sengupta, A. K., Kubicek, S., Mechtler, K., Spahn, L., Koseki, H., Jenuwein, T., and Wutz, A. (2006) Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing EMBO J. 25, 3110-3122 10.1038/sj.emboj.7601187
-
(2006)
EMBO J.
, vol.25
, pp. 3110-3122
-
-
Schoeftner, S.1
Sengupta, A.K.2
Kubicek, S.3
Mechtler, K.4
Spahn, L.5
Koseki, H.6
Jenuwein, T.7
Wutz, A.8
-
22
-
-
34248169728
-
The polycomb group protein Suz12 is required for embryonic stem cell differentiation
-
Pasini, D., Bracken, A. P., Hansen, J. B., Capillo, M., and Helin, K. (2007) The polycomb group protein Suz12 is required for embryonic stem cell differentiation Mol. Cell. Biol. 27, 3769-3779 10.1128/MCB.01432-06
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3769-3779
-
-
Pasini, D.1
Bracken, A.P.2
Hansen, J.B.3
Capillo, M.4
Helin, K.5
-
23
-
-
42149149895
-
Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo
-
Sarma, K., Margueron, R., Ivanov, A., Pirrotta, V., and Reinberg, D. (2008) Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo Mol. Cell. Biol. 28, 2718-2731 10.1128/MCB.02017-07
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 2718-2731
-
-
Sarma, K.1
Margueron, R.2
Ivanov, A.3
Pirrotta, V.4
Reinberg, D.5
-
24
-
-
23944509075
-
The SET-domain protein superfamily: Protein lysine methyltransferases
-
Dillon, S. C., Zhang, X., Trievel, R. C., and Cheng, X. (2005) The SET-domain protein superfamily: protein lysine methyltransferases Genome Biol. 6, 227 10.1186/gb-2005-6-8-227
-
(2005)
Genome Biol.
, vol.6
, pp. 227
-
-
Dillon, S.C.1
Zhang, X.2
Trievel, R.C.3
Cheng, X.4
-
25
-
-
75749124332
-
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
-
Morin, R. D., Johnson, N. A., Severson, T. M., Mungall, A. J., An, J., Goya, R., Paul, J. E., Boyle, M., Woolcock, B. W., Kuchenbauer, F., Yap, D., Humphries, R. K., Griffith, O. L., Shah, S., Zhu, H., Kimbara, M., Shashkin, P., Charlot, J. F., Tcherpakov, M., Corbett, R., Tam, A., Varhol, R., Smailus, D., Moksa, M., Zhao, Y., Delaney, A., Qian, H., Birol, I., Schein, J., Moore, R., Holt, R., Horsman, D. E., Connors, J. M., Jones, S., Aparicio, S., Hirst, M., Gascoyne, R. D., and Marra, M. A. (2010) Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin Nat. Genet. 42, 181-185 10.1038/ng.518
-
(2010)
Nat. Genet.
, vol.42
, pp. 181-185
-
-
Morin, R.D.1
Johnson, N.A.2
Severson, T.M.3
Mungall, A.J.4
An, J.5
Goya, R.6
Paul, J.E.7
Boyle, M.8
Woolcock, B.W.9
Kuchenbauer, F.10
Yap, D.11
Humphries, R.K.12
Griffith, O.L.13
Shah, S.14
Zhu, H.15
Kimbara, M.16
Shashkin, P.17
Charlot, J.F.18
Tcherpakov, M.19
Corbett, R.20
Tam, A.21
Varhol, R.22
Smailus, D.23
Moksa, M.24
Zhao, Y.25
Delaney, A.26
Qian, H.27
Birol, I.28
Schein, J.29
Moore, R.30
Holt, R.31
Horsman, D.E.32
Connors, J.M.33
Jones, S.34
Aparicio, S.35
Hirst, M.36
Gascoyne, R.D.37
Marra, M.A.38
more..
-
26
-
-
79952167230
-
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
-
Yap, D. B., Chu, J., Berg, T., Schapira, M., Cheng, S. W., Moradian, A., Morin, R. D., Mungall, A. J., Meissner, B., Boyle, M., Marquez, V. E., Marra, M. A., Gascoyne, R. D., Humphries, R. K., Arrowsmith, C. H., Morin, G. B., and Aparicio, S. A. (2011) Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation Blood 117, 2451-2459 10.1182/blood-2010-11-321208
-
(2011)
Blood
, vol.117
, pp. 2451-2459
-
-
Yap, D.B.1
Chu, J.2
Berg, T.3
Schapira, M.4
Cheng, S.W.5
Moradian, A.6
Morin, R.D.7
Mungall, A.J.8
Meissner, B.9
Boyle, M.10
Marquez, V.E.11
Marra, M.A.12
Gascoyne, R.D.13
Humphries, R.K.14
Arrowsmith, C.H.15
Morin, G.B.16
Aparicio, S.A.17
-
27
-
-
0025149495
-
Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster
-
Jones, R. S. and Gelbart, W. M. (1990) Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster Genetics 126, 185-199
-
(1990)
Genetics
, vol.126
, pp. 185-199
-
-
Jones, R.S.1
Gelbart, W.M.2
-
28
-
-
0024723075
-
Homeosis and the interaction of zeste and white in Drosophila
-
Wu, C. T., Jones, R. S., Lasko, P. F., and Gelbart, W. M. (1989) Homeosis and the interaction of zeste and white in Drosophila Mol. Gen. Genet. 218, 559-564 10.1007/BF00332424
-
(1989)
Mol. Gen. Genet.
, vol.218
, pp. 559-564
-
-
Wu, C.T.1
Jones, R.S.2
Lasko, P.F.3
Gelbart, W.M.4
-
29
-
-
55549090726
-
Dominant alleles identify SET domain residues required for histone methyltransferase of Polycomb repressive complex 2
-
Joshi, P., Carrington, E. A., Wang, L., Ketel, C. S., Miller, E. L., Jones, R. S., and Simon, J. A. (2008) Dominant alleles identify SET domain residues required for histone methyltransferase of Polycomb repressive complex 2 J. Biol. Chem. 283, 27757-27766 10.1074/jbc.M804442200
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27757-27766
-
-
Joshi, P.1
Carrington, E.A.2
Wang, L.3
Ketel, C.S.4
Miller, E.L.5
Jones, R.S.6
Simon, J.A.7
-
30
-
-
78751662908
-
The Polycomb complex PRC2 and its mark in life
-
Margueron, R. and Reinberg, D. (2011) The Polycomb complex PRC2 and its mark in life Nature 469, 343-349 10.1038/nature09784
-
(2011)
Nature
, vol.469
, pp. 343-349
-
-
Margueron, R.1
Reinberg, D.2
-
31
-
-
84864876023
-
Inner workings and regulatory inputs that control Polycomb repressive complex 2
-
O'Meara, M. M. and Simon, J. A. (2012) Inner workings and regulatory inputs that control Polycomb repressive complex 2 Chromosoma 121, 221-234 10.1007/s00412-012-0361-1
-
(2012)
Chromosoma
, vol.121
, pp. 221-234
-
-
O'Meara, M.M.1
Simon, J.A.2
-
32
-
-
84885393469
-
Transcriptional regulation by Polycomb group proteins
-
Di Croce, L. and Helin, K. (2013) Transcriptional regulation by Polycomb group proteins Nat. Struct. Mol. Biol. 20, 1147-1155 10.1038/nsmb.2669
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1147-1155
-
-
Di Croce, L.1
Helin, K.2
-
33
-
-
84940889106
-
Recruiting polycomb to chromatin
-
van Kruijsbergen, I., Hontelez, S., and Veenstra, G. J. (2015) Recruiting polycomb to chromatin Int. J. Biochem. Cell Biol. 67, 177-187 10.1016/j.biocel.2015.05.006
-
(2015)
Int. J. Biochem. Cell Biol.
, vol.67
, pp. 177-187
-
-
Van Kruijsbergen, I.1
Hontelez, S.2
Veenstra, G.J.3
-
34
-
-
0345046221
-
Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila
-
Kennison, J. A. and Tamkun, J. W. (1988) Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila Proc. Natl. Acad. Sci. U. S. A. 85, 8136-8140 10.1073/pnas.85.21.8136
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 8136-8140
-
-
Kennison, J.A.1
Tamkun, J.W.2
-
35
-
-
0024637850
-
The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related
-
Shearn, A. (1989) The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related Genetics 121, 517-525
-
(1989)
Genetics
, vol.121
, pp. 517-525
-
-
Shearn, A.1
-
36
-
-
71049122240
-
High throughput characterization of combinatorial histone codes
-
Young, N. L., DiMaggio, P. A., Plazas-Mayorca, M. D., Baliban, R. C., Floudas, C. A., and Garcia, B. A. (2009) High throughput characterization of combinatorial histone codes Mol. Cell. Proteomics 8, 2266-2284 10.1074/mcp.M900238-MCP200
-
(2009)
Mol. Cell. Proteomics
, vol.8
, pp. 2266-2284
-
-
Young, N.L.1
DiMaggio, P.A.2
Plazas-Mayorca, M.D.3
Baliban, R.C.4
Floudas, C.A.5
Garcia, B.A.6
-
37
-
-
79953143753
-
H3K36 methylation antagonizes PRC2-mediated H3K27 methylation
-
Yuan, W., Xu, M., Huang, C., Liu, N., Chen, S., and Zhu, B. (2011) H3K36 methylation antagonizes PRC2-mediated H3K27 methylation J. Biol. Chem. 286, 7983-7989 10.1074/jbc.M110.194027
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 7983-7989
-
-
Yuan, W.1
Xu, M.2
Huang, C.3
Liu, N.4
Chen, S.5
Zhu, B.6
-
38
-
-
84867009687
-
Asymmetrically modified nucleosomes
-
Voigt, P., LeRoy, G., Drury, W. J., 3rd, Zee, B. M., Son, J., Beck, D. B., Young, N. L., Garcia, B. A., and Reinberg, D. (2012) Asymmetrically modified nucleosomes Cell 151, 181-193 10.1016/j.cell.2012.09.002
-
(2012)
Cell
, vol.151
, pp. 181-193
-
-
Voigt, P.1
LeRoy, G.2
Drury, W.J.3
Zee, B.M.4
Son, J.5
Beck, D.B.6
Young, N.L.7
Garcia, B.A.8
Reinberg, D.9
-
39
-
-
70350031643
-
CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing
-
Tie, F., Banerjee, R., Stratton, C. A., Prasad-Sinha, J., Stepanik, V., Zlobin, A., Diaz, M. O., Scacheri, P. C., and Harte, P. J. (2009) CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing Development 136, 3131-3141 10.1242/dev.037127
-
(2009)
Development
, vol.136
, pp. 3131-3141
-
-
Tie, F.1
Banerjee, R.2
Stratton, C.A.3
Prasad-Sinha, J.4
Stepanik, V.5
Zlobin, A.6
Diaz, M.O.7
Scacheri, P.C.8
Harte, P.J.9
-
40
-
-
77953973940
-
Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes
-
Pasini, D., Malatesta, M., Jung, H. R., Walfridsson, J., Willer, A., Olsson, L., Skotte, J., Wutz, A., Porse, B., Jensen, O. N., and Helin, K. (2010) Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes Nucleic Acids Res. 38, 4958-4969 10.1093/nar/gkq244
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 4958-4969
-
-
Pasini, D.1
Malatesta, M.2
Jung, H.R.3
Walfridsson, J.4
Willer, A.5
Olsson, L.6
Skotte, J.7
Wutz, A.8
Porse, B.9
Jensen, O.N.10
Helin, K.11
-
41
-
-
77956919550
-
Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation
-
Gehani, S. S., Agrawal-Singh, S., Dietrich, N., Christophersen, N. S., Helin, K., and Hansen, K. (2010) Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation Mol. Cell 39, 886-900 10.1016/j.molcel.2010.08.020
-
(2010)
Mol. Cell
, vol.39
, pp. 886-900
-
-
Gehani, S.S.1
Agrawal-Singh, S.2
Dietrich, N.3
Christophersen, N.S.4
Helin, K.5
Hansen, K.6
-
42
-
-
79952612932
-
Histone code pathway involving H3 S28 phosphorylation and K27 acetylation activates transcription and antagonizes polycomb silencing
-
Lau, P. N. and Cheung, P. (2011) Histone code pathway involving H3 S28 phosphorylation and K27 acetylation activates transcription and antagonizes polycomb silencing Proc. Natl. Acad. Sci. U. S. A. 108, 2801-2806 10.1073/pnas.1012798108
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 2801-2806
-
-
Lau, P.N.1
Cheung, P.2
-
43
-
-
80052571043
-
Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells
-
Stojic, L., Jasencakova, Z., Prezioso, C., Stutzer, A., Bodega, B., Pasini, D., Klingberg, R., Mozzetta, C., Margueron, R., Puri, P. L., Schwarzer, D., Helin, K., Fischle, W., and Orlando, V. (2011) Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells Epigenet. Chromatin 4, 16 10.1186/1756-8935-4-16
-
(2011)
Epigenet. Chromatin
, vol.4
, pp. 16
-
-
Stojic, L.1
Jasencakova, Z.2
Prezioso, C.3
Stutzer, A.4
Bodega, B.5
Pasini, D.6
Klingberg, R.7
Mozzetta, C.8
Margueron, R.9
Puri, P.L.10
Schwarzer, D.11
Helin, K.12
Fischle, W.13
Orlando, V.14
-
44
-
-
84878745222
-
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
-
Kadoch, C., Hargreaves, D. C., Hodges, C., Elias, L., Ho, L., Ranish, J., and Crabtree, G. R. (2013) Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy Nat. Genet. 45, 592-601 10.1038/ng.2628
-
(2013)
Nat. Genet.
, vol.45
, pp. 592-601
-
-
Kadoch, C.1
Hargreaves, D.C.2
Hodges, C.3
Elias, L.4
Ho, L.5
Ranish, J.6
Crabtree, G.R.7
-
45
-
-
84929160944
-
Role of nucleosome remodeling in neurodevelopmental and intellectual disability disorders
-
Lopez, A. J. and Wood, M. A. (2015) Role of nucleosome remodeling in neurodevelopmental and intellectual disability disorders Front. Behav. Neurosci. 9, 100 10.3389/fnbeh.2015.00100
-
(2015)
Front. Behav. Neurosci.
, vol.9
, pp. 100
-
-
Lopez, A.J.1
Wood, M.A.2
-
46
-
-
65249180173
-
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
-
Ho, L., Ronan, J. L., Wu, J., Staahl, B. T., Chen, L., Kuo, A., Lessard, J., Nesvizhskii, A. I., Ranish, J., and Crabtree, G. R. (2009) An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency Proc. Natl. Acad. Sci. U. S. A. 106, 5181-5186 10.1073/pnas.0812889106
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 5181-5186
-
-
Ho, L.1
Ronan, J.L.2
Wu, J.3
Staahl, B.T.4
Chen, L.5
Kuo, A.6
Lessard, J.7
Nesvizhskii, A.I.8
Ranish, J.9
Crabtree, G.R.10
-
47
-
-
0021715020
-
Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae
-
Neigeborn, L. and Carlson, M. (1984) Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae Genetics 108, 845-858
-
(1984)
Genetics
, vol.108
, pp. 845-858
-
-
Neigeborn, L.1
Carlson, M.2
-
48
-
-
0021659727
-
Five SWI genes are required for expression of the HO gene in yeast
-
Stern, M., Jensen, R., and Herskowitz, I. (1984) Five SWI genes are required for expression of the HO gene in yeast J. Mol. Biol. 178, 853-868 10.1016/0022-2836(84)90315-2
-
(1984)
J. Mol. Biol.
, vol.178
, pp. 853-868
-
-
Stern, M.1
Jensen, R.2
Herskowitz, I.3
-
49
-
-
0026584855
-
Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription
-
Peterson, C. L. and Herskowitz, I. (1992) Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription Cell 68, 573-583 10.1016/0092-8674(92)90192-F
-
(1992)
Cell
, vol.68
, pp. 573-583
-
-
Peterson, C.L.1
Herskowitz, I.2
-
50
-
-
0028068714
-
Facilitated binding of TATA-binding protein to nucleosomal DNA
-
Imbalzano, A. N., Kwon, H., Green, M. R., and Kingston, R. E. (1994) Facilitated binding of TATA-binding protein to nucleosomal DNA Nature 370, 481-485 10.1038/370481a0
-
(1994)
Nature
, vol.370
, pp. 481-485
-
-
Imbalzano, A.N.1
Kwon, H.2
Green, M.R.3
Kingston, R.E.4
-
51
-
-
0028093378
-
Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex
-
Kwon, H., Imbalzano, A. N., Khavari, P. A., Kingston, R. E., and Green, M. R. (1994) Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex Nature 370, 477-481 10.1038/370477a0
-
(1994)
Nature
, vol.370
, pp. 477-481
-
-
Kwon, H.1
Imbalzano, A.N.2
Khavari, P.A.3
Kingston, R.E.4
Green, M.R.5
-
52
-
-
67650725820
-
The biology of chromatin remodeling complexes
-
Clapier, C. R. and Cairns, B. R. (2009) The biology of chromatin remodeling complexes Annu. Rev. Biochem. 78, 273-304 10.1146/annurev.biochem.77.062706.153223
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 273-304
-
-
Clapier, C.R.1
Cairns, B.R.2
-
53
-
-
84881166117
-
Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes
-
Narlikar, G. J., Sundaramoorthy, R., and Owen-Hughes, T. (2013) Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes Cell 154, 490-503 10.1016/j.cell.2013.07.011
-
(2013)
Cell
, vol.154
, pp. 490-503
-
-
Narlikar, G.J.1
Sundaramoorthy, R.2
Owen-Hughes, T.3
-
54
-
-
8544270889
-
Baf60c is essential for function of BAF chromatin remodelling complexes in heart development
-
Lickert, H., Takeuchi, J. K., Von Both, I., Walls, J. R., McAuliffe, F., Adamson, S. L., Henkelman, R. M., Wrana, J. L., Rossant, J., and Bruneau, B. G. (2004) Baf60c is essential for function of BAF chromatin remodelling complexes in heart development Nature 432, 107-112 10.1038/nature03071
-
(2004)
Nature
, vol.432
, pp. 107-112
-
-
Lickert, H.1
Takeuchi, J.K.2
Von Both, I.3
Walls, J.R.4
McAuliffe, F.5
Adamson, S.L.6
Henkelman, R.M.7
Wrana, J.L.8
Rossant, J.9
Bruneau, B.G.10
-
55
-
-
67949083572
-
MicroRNA-mediated switching of chromatin-remodelling complexes in neural development
-
Yoo, A. S., Staahl, B. T., Chen, L., and Crabtree, G. R. (2009) MicroRNA-mediated switching of chromatin-remodelling complexes in neural development Nature 460, 642-646 10.1038/nature08139
-
(2009)
Nature
, vol.460
, pp. 642-646
-
-
Yoo, A.S.1
Staahl, B.T.2
Chen, L.3
Crabtree, G.R.4
-
56
-
-
77953727663
-
Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming
-
Singhal, N., Graumann, J., Wu, G., Arauzo-Bravo, M. J., Han, D. W., Greber, B., Gentile, L., Mann, M., and Scholer, H. R. (2010) Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming Cell 141, 943-955 10.1016/j.cell.2010.04.037
-
(2010)
Cell
, vol.141
, pp. 943-955
-
-
Singhal, N.1
Graumann, J.2
Wu, G.3
Arauzo-Bravo, M.J.4
Han, D.W.5
Greber, B.6
Gentile, L.7
Mann, M.8
Scholer, H.R.9
-
57
-
-
79351469421
-
The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting
-
Tea, J. S. and Luo, L. (2011) The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting Neural Dev. 6, 5 10.1186/1749-8104-6-5
-
(2011)
Neural Dev.
, vol.6
, pp. 5
-
-
Tea, J.S.1
Luo, L.2
-
58
-
-
80051684096
-
MicroRNA-mediated conversion of human fibroblasts to neurons
-
Yoo, A. S., Sun, A. X., Li, L., Shcheglovitov, A., Portmann, T., Li, Y., Lee-Messer, C., Dolmetsch, R. E., Tsien, R. W., and Crabtree, G. R. (2011) MicroRNA-mediated conversion of human fibroblasts to neurons Nature 476, 228-231 10.1038/nature10323
-
(2011)
Nature
, vol.476
, pp. 228-231
-
-
Yoo, A.S.1
Sun, A.X.2
Li, L.3
Shcheglovitov, A.4
Portmann, T.5
Li, Y.6
Lee-Messer, C.7
Dolmetsch, R.E.8
Tsien, R.W.9
Crabtree, G.R.10
-
59
-
-
33749016462
-
Targeted disruption of the synovial sarcoma-associated SS18 gene causes early embryonic lethality and affects PPARBP expression
-
de Bruijn, D. R., Peters, W. J., Chuva de Sousa Lopes, S. M., van Dijk, A. H., Willemse, M. P., Pfundt, R., de Boer, P., and Geurts van Kessel, A. (2006) Targeted disruption of the synovial sarcoma-associated SS18 gene causes early embryonic lethality and affects PPARBP expression Hum. Mol. Genet. 15, 2936-2944 10.1093/hmg/ddl235
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 2936-2944
-
-
De Bruijn, D.R.1
Peters, W.J.2
Chuva De Sousa Lopes, S.M.3
Van Dijk, A.H.4
Willemse, M.P.5
Pfundt, R.6
De Boer, P.7
Geurts Van Kessel, A.8
-
60
-
-
84870728704
-
The BAF53a subunit of SWI/SNF-like BAF complexes is essential for hemopoietic stem cell function
-
Krasteva, V., Buscarlet, M., Diaz-Tellez, A., Bernard, M. A., Crabtree, G. R., and Lessard, J. A. (2012) The BAF53a subunit of SWI/SNF-like BAF complexes is essential for hemopoietic stem cell function Blood 120, 4720-4732 10.1182/blood-2012-04-427047
-
(2012)
Blood
, vol.120
, pp. 4720-4732
-
-
Krasteva, V.1
Buscarlet, M.2
Diaz-Tellez, A.3
Bernard, M.A.4
Crabtree, G.R.5
Lessard, J.A.6
-
61
-
-
0036837861
-
HSWI/SNF-catalyzed nucleosome sliding does not occur solely via a twist-diffusion mechanism
-
Aoyagi, S. and Hayes, J. J. (2002) hSWI/SNF-catalyzed nucleosome sliding does not occur solely via a twist-diffusion mechanism Mol. Cell. Biol. 22, 7484-7490 10.1128/MCB.22.21.7484-7490.2002
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7484-7490
-
-
Aoyagi, S.1
Hayes, J.J.2
-
62
-
-
26944433102
-
A 'loop recapture' mechanism for ACF-dependent nucleosome remodeling
-
Strohner, R., Wachsmuth, M., Dachauer, K., Mazurkiewicz, J., Hochstatter, J., Rippe, K., and Langst, G. (2005) A 'loop recapture' mechanism for ACF-dependent nucleosome remodeling Nat. Struct. Mol. Biol. 12, 683-690 10.1038/nsmb966
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 683-690
-
-
Strohner, R.1
Wachsmuth, M.2
Dachauer, K.3
Mazurkiewicz, J.4
Hochstatter, J.5
Rippe, K.6
Langst, G.7
-
63
-
-
0037102562
-
Chromatin remodeling by RSC involves ATP-dependent DNA translocation
-
Saha, A., Wittmeyer, J., and Cairns, B. R. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation Genes Dev. 16, 2120-2134 10.1101/gad.995002
-
(2002)
Genes Dev.
, vol.16
, pp. 2120-2134
-
-
Saha, A.1
Wittmeyer, J.2
Cairns, B.R.3
-
64
-
-
0037370303
-
Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme
-
Whitehouse, I., Stockdale, C., Flaus, A., Szczelkun, M. D., and Owen-Hughes, T. (2003) Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme Mol. Cell. Biol. 23, 1935-1945 10.1128/MCB.23.6.1935-1945.2003
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 1935-1945
-
-
Whitehouse, I.1
Stockdale, C.2
Flaus, A.3
Szczelkun, M.D.4
Owen-Hughes, T.5
-
65
-
-
33744916194
-
Chromatin remodeling by ISW2 and SWI/SNF requires DNA translocation inside the nucleosome
-
Zofall, M., Persinger, J., Kassabov, S. R., and Bartholomew, B. (2006) Chromatin remodeling by ISW2 and SWI/SNF requires DNA translocation inside the nucleosome Nat. Struct. Mol. Biol. 13, 339-346 10.1038/nsmb1071
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 339-346
-
-
Zofall, M.1
Persinger, J.2
Kassabov, S.R.3
Bartholomew, B.4
-
66
-
-
72949099668
-
Dynamics of nucleosome remodelling by individual ACF complexes
-
Blosser, T. R., Yang, J. G., Stone, M. D., Narlikar, G. J., and Zhuang, X. (2009) Dynamics of nucleosome remodelling by individual ACF complexes Nature 462, 1022-1027 10.1038/nature08627
-
(2009)
Nature
, vol.462
, pp. 1022-1027
-
-
Blosser, T.R.1
Yang, J.G.2
Stone, M.D.3
Narlikar, G.J.4
Zhuang, X.5
-
67
-
-
26944461283
-
Chromatin remodeling through directional DNA translocation from an internal nucleosomal site
-
Saha, A., Wittmeyer, J., and Cairns, B. R. (2005) Chromatin remodeling through directional DNA translocation from an internal nucleosomal site Nat. Struct. Mol. Biol. 12, 747-755 10.1038/nsmb973
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 747-755
-
-
Saha, A.1
Wittmeyer, J.2
Cairns, B.R.3
-
68
-
-
4544266390
-
Spatial contacts and nucleosome step movements induced by the NURF chromatin remodeling complex
-
Schwanbeck, R., Xiao, H., and Wu, C. (2004) Spatial contacts and nucleosome step movements induced by the NURF chromatin remodeling complex J. Biol. Chem. 279, 39933-39941 10.1074/jbc.M406060200
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 39933-39941
-
-
Schwanbeck, R.1
Xiao, H.2
Wu, C.3
-
69
-
-
52649141631
-
Architecture of the SWI/SNF-nucleosome complex
-
Dechassa, M. L., Zhang, B., Horowitz-Scherer, R., Persinger, J., Woodcock, C. L., Peterson, C. L., and Bartholomew, B. (2008) Architecture of the SWI/SNF-nucleosome complex Mol. Cell. Biol. 28, 6010-6021 10.1128/MCB.00693-08
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 6010-6021
-
-
Dechassa, M.L.1
Zhang, B.2
Horowitz-Scherer, R.3
Persinger, J.4
Woodcock, C.L.5
Peterson, C.L.6
Bartholomew, B.7
-
70
-
-
13844255150
-
Structural studies of the human PBAF chromatin-remodeling complex
-
Leschziner, A. E., Lemon, B., Tjian, R., and Nogales, E. (2005) Structural studies of the human PBAF chromatin-remodeling complex Structure 13, 267-275 10.1016/j.str.2004.12.008
-
(2005)
Structure
, vol.13
, pp. 267-275
-
-
Leschziner, A.E.1
Lemon, B.2
Tjian, R.3
Nogales, E.4
-
71
-
-
57149115121
-
Structure of a RSC-nucleosome complex and insights into chromatin remodeling
-
Chaban, Y., Ezeokonkwo, C., Chung, W. H., Zhang, F., Kornberg, R. D., Maier-Davis, B., Lorch, Y., and Asturias, F. J. (2008) Structure of a RSC-nucleosome complex and insights into chromatin remodeling Nat. Struct. Mol. Biol. 15, 1272-1277 10.1038/nsmb.1524
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 1272-1277
-
-
Chaban, Y.1
Ezeokonkwo, C.2
Chung, W.H.3
Zhang, F.4
Kornberg, R.D.5
Maier-Davis, B.6
Lorch, Y.7
Asturias, F.J.8
-
72
-
-
77649246568
-
Mechanism of chromatin remodeling
-
Lorch, Y., Maier-Davis, B., and Kornberg, R. D. (2010) Mechanism of chromatin remodeling Proc. Natl. Acad. Sci. U. S. A. 107, 3458-3462 10.1073/pnas.1000398107
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 3458-3462
-
-
Lorch, Y.1
Maier-Davis, B.2
Kornberg, R.D.3
-
73
-
-
18744364437
-
Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54
-
Thoma, N. H., Czyzewski, B. K., Alexeev, A. A., Mazin, A. V., Kowalczykowski, S. C., and Pavletich, N. P. (2005) Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54 Nat. Struct. Mol. Biol. 12, 350-356 10.1038/nsmb919
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 350-356
-
-
Thoma, N.H.1
Czyzewski, B.K.2
Alexeev, A.A.3
Mazin, A.V.4
Kowalczykowski, S.C.5
Pavletich, N.P.6
-
74
-
-
75749101495
-
Chromatin remodelling during development
-
Ho, L. and Crabtree, G. R. (2010) Chromatin remodelling during development Nature 463, 474-484 10.1038/nature08911
-
(2010)
Nature
, vol.463
, pp. 474-484
-
-
Ho, L.1
Crabtree, G.R.2
-
75
-
-
0027295019
-
The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation
-
Laurent, B. C., Treich, I., and Carlson, M. (1993) The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation Genes Dev. 7, 583-591 10.1101/gad.7.4.583
-
(1993)
Genes Dev.
, vol.7
, pp. 583-591
-
-
Laurent, B.C.1
Treich, I.2
Carlson, M.3
-
76
-
-
0031932620
-
Genetic analysis of brahma: The Drosophila homolog of the yeast chromatin remodeling factor SWI2/SNF2
-
Elfring, L. K., Daniel, C., Papoulas, O., Deuring, R., Sarte, M., Moseley, S., Beek, S. J., Waldrip, W. R., Daubresse, G., DePace, A., Kennison, J. A., and Tamkun, J. W. (1998) Genetic analysis of brahma: the Drosophila homolog of the yeast chromatin remodeling factor SWI2/SNF2 Genetics 148, 251-265
-
(1998)
Genetics
, vol.148
, pp. 251-265
-
-
Elfring, L.K.1
Daniel, C.2
Papoulas, O.3
Deuring, R.4
Sarte, M.5
Moseley, S.6
Beek, S.J.7
Waldrip, W.R.8
Daubresse, G.9
DePace, A.10
Kennison, J.A.11
Tamkun, J.W.12
-
77
-
-
0032567080
-
Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling
-
Zhao, K., Wang, W., Rando, O. J., Xue, Y., Swiderek, K., Kuo, A., and Crabtree, G. R. (1998) Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling Cell 95, 625-636 10.1016/S0092-8674(00)81633-5
-
(1998)
Cell
, vol.95
, pp. 625-636
-
-
Zhao, K.1
Wang, W.2
Rando, O.J.3
Xue, Y.4
Swiderek, K.5
Kuo, A.6
Crabtree, G.R.7
-
78
-
-
44349105786
-
ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a
-
Gao, X., Tate, P., Hu, P., Tjian, R., Skarnes, W. C., and Wang, Z. (2008) ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a Proc. Natl. Acad. Sci. U. S. A. 105, 6656-6661 10.1073/pnas.0801802105
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 6656-6661
-
-
Gao, X.1
Tate, P.2
Hu, P.3
Tjian, R.4
Skarnes, W.C.5
Wang, Z.6
-
79
-
-
57749105431
-
BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells
-
Kaeser, M. D., Aslanian, A., Dong, M. Q., Yates, J. R., 3rd, and Emerson, B. M. (2008) BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells J. Biol. Chem. 283, 32254-32263 10.1074/jbc.M806061200
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 32254-32263
-
-
Kaeser, M.D.1
Aslanian, A.2
Dong, M.Q.3
Yates, J.R.4
Emerson, B.M.5
-
80
-
-
62549095522
-
SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells
-
Kidder, B. L., Palmer, S., and Knott, J. G. (2009) SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells Stem Cells 27, 317-328 10.1634/stemcells.2008-0710
-
(2009)
Stem Cells
, vol.27
, pp. 317-328
-
-
Kidder, B.L.1
Palmer, S.2
Knott, J.G.3
-
81
-
-
0034502484
-
A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes
-
Bultman, S., Gebuhr, T., Yee, D., La Mantia, C., Nicholson, J., Gilliam, A., Randazzo, F., Metzger, D., Chambon, P., Crabtree, G., and Magnuson, T. (2000) A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes Mol. Cell 6, 1287-1295 10.1016/S1097-2765(00)00127-1
-
(2000)
Mol. Cell
, vol.6
, pp. 1287-1295
-
-
Bultman, S.1
Gebuhr, T.2
Yee, D.3
La Mantia, C.4
Nicholson, J.5
Gilliam, A.6
Randazzo, F.7
Metzger, D.8
Chambon, P.9
Crabtree, G.10
Magnuson, T.11
-
82
-
-
0032403109
-
Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha)
-
Reyes, J. C., Barra, J., Muchardt, C., Camus, A., Babinet, C., and Yaniv, M. (1998) Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha) EMBO J. 17, 6979-6991 10.1093/emboj/17.23.6979
-
(1998)
EMBO J.
, vol.17
, pp. 6979-6991
-
-
Reyes, J.C.1
Barra, J.2
Muchardt, C.3
Camus, A.4
Babinet, C.5
Yaniv, M.6
-
83
-
-
84958527960
-
Induction of functional Brm protein from Brm knockout mice
-
Thompson, K. W., Marquez, S. B., Lu, L., and Reisman, D. (2015) Induction of functional Brm protein from Brm knockout mice Oncoscience 2, 349-361 10.18632/oncoscience.153
-
(2015)
Oncoscience
, vol.2
, pp. 349-361
-
-
Thompson, K.W.1
Marquez, S.B.2
Lu, L.3
Reisman, D.4
-
84
-
-
34447249019
-
An essential switch in subunit composition of a chromatin remodeling complex during neural development
-
Lessard, J., Wu, J. I., Ranish, J. A., Wan, M., Winslow, M. M., Staahl, B. T., Wu, H., Aebersold, R., Graef, I. A., and Crabtree, G. R. (2007) An essential switch in subunit composition of a chromatin remodeling complex during neural development Neuron 55, 201-215 10.1016/j.neuron.2007.06.019
-
(2007)
Neuron
, vol.55
, pp. 201-215
-
-
Lessard, J.1
Wu, J.I.2
Ranish, J.A.3
Wan, M.4
Winslow, M.M.5
Staahl, B.T.6
Wu, H.7
Aebersold, R.8
Graef, I.A.9
Crabtree, G.R.10
-
85
-
-
34748887795
-
Regulation of dendritic development by neuron-specific chromatin remodeling complexes
-
Wu, J. I., Lessard, J., Olave, I. A., Qiu, Z., Ghosh, A., Graef, I. A., and Crabtree, G. R. (2007) Regulation of dendritic development by neuron-specific chromatin remodeling complexes Neuron 56, 94-108 10.1016/j.neuron.2007.08.021
-
(2007)
Neuron
, vol.56
, pp. 94-108
-
-
Wu, J.I.1
Lessard, J.2
Olave, I.A.3
Qiu, Z.4
Ghosh, A.5
Graef, I.A.6
Crabtree, G.R.7
-
86
-
-
33645514645
-
Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites
-
Parrish, J. Z., Kim, M. D., Jan, L. Y., and Jan, Y. N. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites Genes Dev. 20, 820-835 10.1101/gad.1391006
-
(2006)
Genes Dev.
, vol.20
, pp. 820-835
-
-
Parrish, J.Z.1
Kim, M.D.2
Jan, L.Y.3
Jan, Y.N.4
-
87
-
-
84879136007
-
Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways
-
Staahl, B. T., Tang, J., Wu, W., Sun, A., Gitler, A. D., Yoo, A. S., and Crabtree, G. R. (2013) Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways J. Neurosci. 33, 10348-10361 10.1523/JNEUROSCI.1258-13.2013
-
(2013)
J. Neurosci.
, vol.33
, pp. 10348-10361
-
-
Staahl, B.T.1
Tang, J.2
Wu, W.3
Sun, A.4
Gitler, A.D.5
Yoo, A.S.6
Crabtree, G.R.7
-
88
-
-
77955321344
-
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
-
Ieda, M., Fu, J. D., Delgado-Olguin, P., Vedantham, V., Hayashi, Y., Bruneau, B. G., and Srivastava, D. (2010) Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors Cell 142, 375-386 10.1016/j.cell.2010.07.002
-
(2010)
Cell
, vol.142
, pp. 375-386
-
-
Ieda, M.1
Fu, J.D.2
Delgado-Olguin, P.3
Vedantham, V.4
Hayashi, Y.5
Bruneau, B.G.6
Srivastava, D.7
-
89
-
-
84875727068
-
Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma
-
Kadoch, C. and Crabtree, G. R. (2013) Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma Cell 153, 71-85 10.1016/j.cell.2013.02.036
-
(2013)
Cell
, vol.153
, pp. 71-85
-
-
Kadoch, C.1
Crabtree, G.R.2
-
90
-
-
85041801996
-
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics
-
Kadoch, C. and Crabtree, G. R. (2015) Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics Science Advances 1, e1500447 10.1126/sciadv.1500447
-
(2015)
Science Advances
, vol.1
-
-
Kadoch, C.1
Crabtree, G.R.2
-
91
-
-
84925394779
-
Diverse involvement of EZH2 in cancer epigenetics
-
Volkel, P., Dupret, B., Le Bourhis, X., and Angrand, P. O. (2015) Diverse involvement of EZH2 in cancer epigenetics Am. J. Transl Res. 7, 175-193
-
(2015)
Am. J. Transl Res.
, vol.7
, pp. 175-193
-
-
Volkel, P.1
Dupret, B.2
Le Bourhis, X.3
Angrand, P.O.4
-
92
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber, J., Korshunov, A., Liu, X. Y., Jones, D. T., Pfaff, E., Jacob, K., Sturm, D., Fontebasso, A. M., Quang, D. A., Tonjes, M., Hovestadt, V., Albrecht, S., Kool, M., Nantel, A., Konermann, C., Lindroth, A., Jager, N., Rausch, T., Ryzhova, M., Korbel, J. O., Hielscher, T., Hauser, P., Garami, M., Klekner, A., Bognar, L., Ebinger, M., Schuhmann, M. U., Scheurlen, W., Pekrun, A., Fruhwald, M. C., Roggendorf, W., Kramm, C., Durken, M., Atkinson, J., Lepage, P., Montpetit, A., Zakrzewska, M., Zakrzewski, K., Liberski, P. P., Dong, Z., Siegel, P., Kulozik, A. E., Zapatka, M., Guha, A., Malkin, D., Felsberg, J., Reifenberger, G., von Deimling, A., Ichimura, K., Collins, V. P., Witt, H., Milde, T., Witt, O., Zhang, C., Castelo-Branco, P., Lichter, P., Faury, D., Tabori, U., Plass, C., Majewski, J., Pfister, S. M., and Jabado, N. (2012) Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma Nature 482, 226-231 10.1038/nature10833
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
Jones, D.T.4
Pfaff, E.5
Jacob, K.6
Sturm, D.7
Fontebasso, A.M.8
Quang, D.A.9
Tonjes, M.10
Hovestadt, V.11
Albrecht, S.12
Kool, M.13
Nantel, A.14
Konermann, C.15
Lindroth, A.16
Jager, N.17
Rausch, T.18
Ryzhova, M.19
Korbel, J.O.20
Hielscher, T.21
Hauser, P.22
Garami, M.23
Klekner, A.24
Bognar, L.25
Ebinger, M.26
Schuhmann, M.U.27
Scheurlen, W.28
Pekrun, A.29
Fruhwald, M.C.30
Roggendorf, W.31
Kramm, C.32
Durken, M.33
Atkinson, J.34
Lepage, P.35
Montpetit, A.36
Zakrzewska, M.37
Zakrzewski, K.38
Liberski, P.P.39
Dong, Z.40
Siegel, P.41
Kulozik, A.E.42
Zapatka, M.43
Guha, A.44
Malkin, D.45
Felsberg, J.46
Reifenberger, G.47
Von Deimling, A.48
Ichimura, K.49
Collins, V.P.50
Witt, H.51
Milde, T.52
Witt, O.53
Zhang, C.54
Castelo-Branco, P.55
Lichter, P.56
Faury, D.57
Tabori, U.58
Plass, C.59
Majewski, J.60
Pfister, S.M.61
Jabado, N.62
more..
-
93
-
-
84862777410
-
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
-
Wu, G., Broniscer, A., McEachron, T. A., Lu, C., Paugh, B. S., Becksfort, J., Qu, C., Ding, L., Huether, R., Parker, M., Zhang, J., Gajjar, A., Dyer, M. A., Mullighan, C. G., Gilbertson, R. J., Mardis, E. R., Wilson, R. K., Downing, J. R., Ellison, D. W., Zhang, J., and Baker, S. J. (2012) Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas Nat. Genet. 44, 251-253 10.1038/ng.1102
-
(2012)
Nat. Genet.
, vol.44
, pp. 251-253
-
-
Wu, G.1
Broniscer, A.2
McEachron, T.A.3
Lu, C.4
Paugh, B.S.5
Becksfort, J.6
Qu, C.7
Ding, L.8
Huether, R.9
Parker, M.10
Zhang, J.11
Gajjar, A.12
Dyer, M.A.13
Mullighan, C.G.14
Gilbertson, R.J.15
Mardis, E.R.16
Wilson, R.K.17
Downing, J.R.18
Ellison, D.W.19
Zhang, J.20
Baker, S.J.21
more..
-
94
-
-
84877785024
-
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
-
Lewis, P. W., Muller, M. M., Koletsky, M. S., Cordero, F., Lin, S., Banaszynski, L. A., Garcia, B. A., Muir, T. W., Becher, O. J., and Allis, C. D. (2013) Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma Science 340, 857-861 10.1126/science.1232245
-
(2013)
Science
, vol.340
, pp. 857-861
-
-
Lewis, P.W.1
Muller, M.M.2
Koletsky, M.S.3
Cordero, F.4
Lin, S.5
Banaszynski, L.A.6
Garcia, B.A.7
Muir, T.W.8
Becher, O.J.9
Allis, C.D.10
-
95
-
-
84877299145
-
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
-
Chan, K. M., Fang, D., Gan, H., Hashizume, R., Yu, C., Schroeder, M., Gupta, N., Mueller, S., James, C. D., Jenkins, R., Sarkaria, J., and Zhang, Z. (2013) The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression Genes Dev. 27, 985-990 10.1101/gad.217778.113
-
(2013)
Genes Dev.
, vol.27
, pp. 985-990
-
-
Chan, K.M.1
Fang, D.2
Gan, H.3
Hashizume, R.4
Yu, C.5
Schroeder, M.6
Gupta, N.7
Mueller, S.8
James, C.D.9
Jenkins, R.10
Sarkaria, J.11
Zhang, Z.12
-
96
-
-
84920196792
-
Rhabdoid tumors: Integrating biological insights with clinical success: A report from the SMARCB1 and Rhabdoid Tumor Symposium, Paris, December 12-14, 2013
-
Bourdeaut, F., Chi, S. N., and Fruhwald, M. C. (2014) Rhabdoid tumors: integrating biological insights with clinical success: a report from the SMARCB1 and Rhabdoid Tumor Symposium, Paris, December 12-14, 2013 Cancer Genet. 207, 346-351 10.1016/j.cancergen.2014.10.004
-
(2014)
Cancer Genet.
, vol.207
, pp. 346-351
-
-
Bourdeaut, F.1
Chi, S.N.2
Fruhwald, M.C.3
-
97
-
-
2642647094
-
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
-
Versteege, I., Sevenet, N., Lange, J., Rousseau-Merck, M. F., Ambros, P., Handgretinger, R., Aurias, A., and Delattre, O. (1998) Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer Nature 394, 203-206 10.1038/28212
-
(1998)
Nature
, vol.394
, pp. 203-206
-
-
Versteege, I.1
Sevenet, N.2
Lange, J.3
Rousseau-Merck, M.F.4
Ambros, P.5
Handgretinger, R.6
Aurias, A.7
Delattre, O.8
-
98
-
-
79957975801
-
Nonsense mutation and inactivation of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression
-
Hasselblatt, M., Gesk, S., Oyen, F., Rossi, S., Viscardi, E., Giangaspero, F., Giannini, C., Judkins, A. R., Fruhwald, M. C., Obser, T., Schneppenheim, R., Siebert, R., and Paulus, W. (2011) Nonsense mutation and inactivation of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression Am. J. Surg Pathol 35, 933-935 10.1097/PAS.0b013e3182196a39
-
(2011)
Am. J. Surg Pathol
, vol.35
, pp. 933-935
-
-
Hasselblatt, M.1
Gesk, S.2
Oyen, F.3
Rossi, S.4
Viscardi, E.5
Giangaspero, F.6
Giannini, C.7
Judkins, A.R.8
Fruhwald, M.C.9
Obser, T.10
Schneppenheim, R.11
Siebert, R.12
Paulus, W.13
-
99
-
-
84920121902
-
Pathology and diagnosis of SMARCB1-deficient tumors
-
Margol, A. S. and Judkins, A. R. (2014) Pathology and diagnosis of SMARCB1-deficient tumors Cancer Genet. 207, 358-364 10.1016/j.cancergen.2014.07.004
-
(2014)
Cancer Genet.
, vol.207
, pp. 358-364
-
-
Margol, A.S.1
Judkins, A.R.2
-
100
-
-
84864746573
-
A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers
-
Lee, R. S., Stewart, C., Carter, S. L., Ambrogio, L., Cibulskis, K., Sougnez, C., Lawrence, M. S., Auclair, D., Mora, J., Golub, T. R., Biegel, J. A., Getz, G., and Roberts, C. W. (2012) A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers J. Clin. Invest. 122, 2983-2988 10.1172/JCI64400
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2983-2988
-
-
Lee, R.S.1
Stewart, C.2
Carter, S.L.3
Ambrogio, L.4
Cibulskis, K.5
Sougnez, C.6
Lawrence, M.S.7
Auclair, D.8
Mora, J.9
Golub, T.R.10
Biegel, J.A.11
Getz, G.12
Roberts, C.W.13
-
101
-
-
77957955244
-
Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation
-
Wilson, B. G., Wang, X., Shen, X., McKenna, E. S., Lemieux, M. E., Cho, Y. J., Koellhoffer, E. C., Pomeroy, S. L., Orkin, S. H., and Roberts, C. W. (2010) Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation Cancer Cell 18, 316-328 10.1016/j.ccr.2010.09.006
-
(2010)
Cancer Cell
, vol.18
, pp. 316-328
-
-
Wilson, B.G.1
Wang, X.2
Shen, X.3
McKenna, E.S.4
Lemieux, M.E.5
Cho, Y.J.6
Koellhoffer, E.C.7
Pomeroy, S.L.8
Orkin, S.H.9
Roberts, C.W.10
-
102
-
-
43249130490
-
SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus
-
Kia, S. K., Gorski, M. M., Giannakopoulos, S., and Verrijzer, C. P. (2008) SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus Mol. Cell. Biol. 28, 3457-3464 10.1128/MCB.02019-07
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3457-3464
-
-
Kia, S.K.1
Gorski, M.M.2
Giannakopoulos, S.3
Verrijzer, C.P.4
-
103
-
-
84877324084
-
Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2
-
Knutson, S. K., Warholic, N. M., Wigle, T. J., Klaus, C. R., Allain, C. J., Raimondi, A., Porter Scott, M., Chesworth, R., Moyer, M. P., Copeland, R. A., Richon, V. M., Pollock, R. M., Kuntz, K. W., and Keilhack, H. (2013) Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2 Proc. Natl. Acad. Sci. U. S. A. 110, 7922-7927 10.1073/pnas.1303800110
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 7922-7927
-
-
Knutson, S.K.1
Warholic, N.M.2
Wigle, T.J.3
Klaus, C.R.4
Allain, C.J.5
Raimondi, A.6
Porter Scott, M.7
Chesworth, R.8
Moyer, M.P.9
Copeland, R.A.10
Richon, V.M.11
Pollock, R.M.12
Kuntz, K.W.13
Keilhack, H.14
-
104
-
-
70350225510
-
Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex
-
Wang, X., Sansam, C. G., Thom, C. S., Metzger, D., Evans, J. A., Nguyen, P. T., and Roberts, C. W. (2009) Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex Cancer Res. 69, 8094-8101 10.1158/0008-5472.CAN-09-0733
-
(2009)
Cancer Res.
, vol.69
, pp. 8094-8101
-
-
Wang, X.1
Sansam, C.G.2
Thom, C.S.3
Metzger, D.4
Evans, J.A.5
Nguyen, P.T.6
Roberts, C.W.7
-
105
-
-
84902084206
-
The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors
-
Kahali, B., Yu, J., Marquez, S. B., Thompson, K. W., Liang, S. Y., Lu, L., and Reisman, D. (2014) The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors Oncotarget 5, 3316-3332 10.18632/oncotarget.1945
-
(2014)
Oncotarget
, vol.5
, pp. 3316-3332
-
-
Kahali, B.1
Yu, J.2
Marquez, S.B.3
Thompson, K.W.4
Liang, S.Y.5
Lu, L.6
Reisman, D.7
-
106
-
-
84956774384
-
Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcemic type
-
Karnezis, A. N., Wang, Y., Ramos, P., Hendricks, W. P., Oliva, E., D'Angelo, E., Prat, J., Nucci, M. R., Nielsen, T. O., Chow, C., Leung, S., Kommoss, F., Kommoss, S., Silva, A., Ronnett, B. M., Rabban, J. T., Bowtell, D. D., Weissman, B. E., Trent, J. M., Gilks, C. B., and Huntsman, D. G. (2016) Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcemic type J. Pathol. 238, 389 10.1002/path.4633
-
(2016)
J. Pathol.
, vol.238
, pp. 389
-
-
Karnezis, A.N.1
Wang, Y.2
Ramos, P.3
Hendricks, W.P.4
Oliva, E.5
D'Angelo, E.6
Prat, J.7
Nucci, M.R.8
Nielsen, T.O.9
Chow, C.10
Leung, S.11
Kommoss, F.12
Kommoss, S.13
Silva, A.14
Ronnett, B.M.15
Rabban, J.T.16
Bowtell, D.D.17
Weissman, B.E.18
Trent, J.M.19
Gilks, C.B.20
Huntsman, D.G.21
more..
-
107
-
-
84942992175
-
SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas
-
Le Loarer, F., Watson, S., Pierron, G., de Montpreville, V. T., Ballet, S., Firmin, N., Auguste, A., Pissaloux, D., Boyault, S., Paindavoine, S., Dechelotte, P. J., Besse, B., Vignaud, J. M., Brevet, M., Fadel, E., Richer, W., Treilleux, I., Masliah-Planchon, J., Devouassoux-Shisheboran, M., Zalcman, G., Allory, Y., Bourdeaut, F., Thivolet-Bejui, F., Ranchere-Vince, D., Girard, N., Lantuejoul, S., Galateau-Salle, F., Coindre, J. M., Leary, A., Delattre, O., Blay, J. Y., and Tirode, F. (2015) SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas Nat. Genet. 47, 1200-1205 10.1038/ng.3399
-
(2015)
Nat. Genet.
, vol.47
, pp. 1200-1205
-
-
Le Loarer, F.1
Watson, S.2
Pierron, G.3
De Montpreville, V.T.4
Ballet, S.5
Firmin, N.6
Auguste, A.7
Pissaloux, D.8
Boyault, S.9
Paindavoine, S.10
Dechelotte, P.J.11
Besse, B.12
Vignaud, J.M.13
Brevet, M.14
Fadel, E.15
Richer, W.16
Treilleux, I.17
Masliah-Planchon, J.18
Devouassoux-Shisheboran, M.19
Zalcman, G.20
Allory, Y.21
Bourdeaut, F.22
Thivolet-Bejui, F.23
Ranchere-Vince, D.24
Girard, N.25
Lantuejoul, S.26
Galateau-Salle, F.27
Coindre, J.M.28
Leary, A.29
Delattre, O.30
Blay, J.Y.31
Tirode, F.32
more..
-
108
-
-
0034326257
-
BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines
-
Wong, A. K., Shanahan, F., Chen, Y., Lian, L., Ha, P., Hendricks, K., Ghaffari, S., Iliev, D., Penn, B., Woodland, A. M., Smith, R., Salada, G., Carillo, A., Laity, K., Gupte, J., Swedlund, B., Tavtigian, S. V., Teng, D. H., and Lees, E. (2000) BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines Cancer Res. 60, 6171-6177
-
(2000)
Cancer Res.
, vol.60
, pp. 6171-6177
-
-
Wong, A.K.1
Shanahan, F.2
Chen, Y.3
Lian, L.4
Ha, P.5
Hendricks, K.6
Ghaffari, S.7
Iliev, D.8
Penn, B.9
Woodland, A.M.10
Smith, R.11
Salada, G.12
Carillo, A.13
Laity, K.14
Gupte, J.15
Swedlund, B.16
Tavtigian, S.V.17
Teng, D.H.18
Lees, E.19
-
109
-
-
85047698804
-
Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: Differential effects on RB-mediated growth arrest vs CD44 expression
-
Reisman, D. N., Strobeck, M. W., Betz, B. L., Sciariotta, J., Funkhouser, W., Jr., Murchardt, C., Yaniv, M., Sherman, L. S., Knudsen, E. S., and Weissman, B. E. (2002) Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression Oncogene 21, 1196-1207 10.1038/sj.onc.1205188
-
(2002)
Oncogene
, vol.21
, pp. 1196-1207
-
-
Reisman, D.N.1
Strobeck, M.W.2
Betz, B.L.3
Sciariotta, J.4
Funkhouser, W.5
Murchardt, C.6
Yaniv, M.7
Sherman, L.S.8
Knudsen, E.S.9
Weissman, B.E.10
-
110
-
-
84962108647
-
A phase 1 study of EPZ6438 (E7438), an Enhancer of ZesteHomolog 2 (EZH2) inhibitor: Preliminary activity in INI1-negative tumors
-
Italiano, A., Keilhack, H., Toulmonde, M., Coindre, J. M., Michot, J. M., Massard, C., Ottesen, L., Reyderman, L., Blakemore, S. J., Kraljevic, S., Thomson, B., McDonald, A., Ho, P. T., and Ribrag, V. A phase 1 study of EPZ6438 (E7438), an Enhancer of ZesteHomolog 2 (EZH2) inhibitor: Preliminary activity in INI1-negative tumors. Annals of Oncology, ESMO 2015.
-
(2015)
Annals of Oncology, ESMO
-
-
Italiano, A.1
Keilhack, H.2
Toulmonde, M.3
Coindre, J.M.4
Michot, J.M.5
Massard, C.6
Ottesen, L.7
Reyderman, L.8
Blakemore, S.J.9
Kraljevic, S.10
Thomson, B.11
McDonald, A.12
Ho, P.T.13
Ribrag, V.14
-
111
-
-
84902358492
-
No small surprise - Small cell carcinoma of the ovary, hypercalcaemic type, is a malignant rhabdoid tumour
-
Foulkes, W. D., Clarke, B. A., Hasselblatt, M., Majewski, J., Albrecht, S., and McCluggage, W. G. (2014) No small surprise-small cell carcinoma of the ovary, hypercalcaemic type, is a malignant rhabdoid tumour J. Pathol 233, 209-214 10.1002/path.4362
-
(2014)
J. Pathol
, vol.233
, pp. 209-214
-
-
Foulkes, W.D.1
Clarke, B.A.2
Hasselblatt, M.3
Majewski, J.4
Albrecht, S.5
McCluggage, W.G.6
-
112
-
-
84894251347
-
Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation
-
Wilson, B. G., Helming, K. C., Wang, X., Kim, Y., Vazquez, F., Jagani, Z., Hahn, W. C., and Roberts, C. W. (2014) Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation Mol. Cell. Biol. 34, 1136-1144 10.1128/MCB.01372-13
-
(2014)
Mol. Cell. Biol.
, vol.34
, pp. 1136-1144
-
-
Wilson, B.G.1
Helming, K.C.2
Wang, X.3
Kim, Y.4
Vazquez, F.5
Jagani, Z.6
Hahn, W.C.7
Roberts, C.W.8
-
113
-
-
84896898658
-
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers
-
Hoffman, G. R., Rahal, R., Buxton, F., Xiang, K., McAllister, G., Frias, E., Bagdasarian, L., Huber, J., Lindeman, A., Chen, D., Romero, R., Ramadan, N., Phadke, T., Haas, K., Jaskelioff, M., Wilson, B. G., Meyer, M. J., Saenz-Vash, V., Zhai, H., Myer, V. E., Porter, J. A., Keen, N., McLaughlin, M. E., Mickanin, C., Roberts, C. W., Stegmeier, F., and Jagani, Z. (2014) Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers Proc. Natl. Acad. Sci. U. S. A. 111, 3128-3133 10.1073/pnas.1316793111
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 3128-3133
-
-
Hoffman, G.R.1
Rahal, R.2
Buxton, F.3
Xiang, K.4
McAllister, G.5
Frias, E.6
Bagdasarian, L.7
Huber, J.8
Lindeman, A.9
Chen, D.10
Romero, R.11
Ramadan, N.12
Phadke, T.13
Haas, K.14
Jaskelioff, M.15
Wilson, B.G.16
Meyer, M.J.17
Saenz-Vash, V.18
Zhai, H.19
Myer, V.E.20
Porter, J.A.21
Keen, N.22
McLaughlin, M.E.23
Mickanin, C.24
Roberts, C.W.25
Stegmeier, F.26
Jagani, Z.27
more..
-
114
-
-
84942897601
-
The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies
-
Vangamudi, B., Paul, T. A., Shah, P. K., Kost-Alimova, M., Nottebaum, L., Shi, X., Zhan, Y., Leo, E., Mahadeshwar, H. S., Protopopov, A., Futreal, A., Tieu, T. N., Peoples, M., Heffernan, T. P., Marszalek, J. R., Toniatti, C., Petrocchi, A., Verhelle, D., Owen, D. R., Draetta, G., Jones, P., Palmer, W. S., Sharma, S., and Andersen, J. N. (2015) The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies Cancer Res. 75, 3865-3878 10.1158/0008-5472.CAN-14-3798
-
(2015)
Cancer Res.
, vol.75
, pp. 3865-3878
-
-
Vangamudi, B.1
Paul, T.A.2
Shah, P.K.3
Kost-Alimova, M.4
Nottebaum, L.5
Shi, X.6
Zhan, Y.7
Leo, E.8
Mahadeshwar, H.S.9
Protopopov, A.10
Futreal, A.11
Tieu, T.N.12
Peoples, M.13
Heffernan, T.P.14
Marszalek, J.R.15
Toniatti, C.16
Petrocchi, A.17
Verhelle, D.18
Owen, D.R.19
Draetta, G.20
Jones, P.21
Palmer, W.S.22
Sharma, S.23
Andersen, J.N.24
more..
-
115
-
-
84927547043
-
EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors
-
Fillmore, C. M., Xu, C., Desai, P. T., Berry, J. M., Rowbotham, S. P., Lin, Y. J., Zhang, H., Marquez, V. E., Hammerman, P. S., Wong, K. K., and Kim, C. F. (2015) EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors Nature 520, 239-242 10.1038/nature14122
-
(2015)
Nature
, vol.520
, pp. 239-242
-
-
Fillmore, C.M.1
Xu, C.2
Desai, P.T.3
Berry, J.M.4
Rowbotham, S.P.5
Lin, Y.J.6
Zhang, H.7
Marquez, V.E.8
Hammerman, P.S.9
Wong, K.K.10
Kim, C.F.11
-
116
-
-
77953389461
-
Tissue-specific p19Arf regulation dictates the response to oncogenic K-ras
-
Young, N. P. and Jacks, T. (2010) Tissue-specific p19Arf regulation dictates the response to oncogenic K-ras Proc. Natl. Acad. Sci. U. S. A. 107, 10184-10189 10.1073/pnas.1004796107
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 10184-10189
-
-
Young, N.P.1
Jacks, T.2
-
117
-
-
0027933151
-
Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma
-
Clark, J., Rocques, P. J., Crew, A. J., Gill, S., Shipley, J., Chan, A. M., Gusterson, B. A., and Cooper, C. S. (1994) Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma Nat. Genet. 7, 502-508 10.1038/ng0894-502
-
(1994)
Nat. Genet.
, vol.7
, pp. 502-508
-
-
Clark, J.1
Rocques, P.J.2
Crew, A.J.3
Gill, S.4
Shipley, J.5
Chan, A.M.6
Gusterson, B.A.7
Cooper, C.S.8
-
118
-
-
84925502851
-
Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
-
Bitler, B. G., Aird, K. M., Garipov, A., Li, H., Amatangelo, M., Kossenkov, A. V., Schultz, D. C., Liu, Q., Shih, I.-M., Conejo-Garcia, J. R., Speicher, D. W., and Zhang, R. (2015) Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers Nat. Med. 21, 231-238 10.1038/nm.3799
-
(2015)
Nat. Med.
, vol.21
, pp. 231-238
-
-
Bitler, B.G.1
Aird, K.M.2
Garipov, A.3
Li, H.4
Amatangelo, M.5
Kossenkov, A.V.6
Schultz, D.C.7
Liu, Q.8
Shih, I.-M.9
Conejo-Garcia, J.R.10
Speicher, D.W.11
Zhang, R.12
-
119
-
-
84896126029
-
ARID1B is a specific vulnerability in ARID1A-mutant cancers
-
Helming, K. C., Wang, X., Wilson, B. G., Vazquez, F., Haswell, J. R., Manchester, H. E., Kim, Y., Kryukov, G. V., Ghandi, M., Aguirre, A. J., Jagani, Z., Wang, Z., Garraway, L. A., Hahn, W. C., and Roberts, C. W. (2014) ARID1B is a specific vulnerability in ARID1A-mutant cancers Nat. Med. 20, 251-254 10.1038/nm.3480
-
(2014)
Nat. Med.
, vol.20
, pp. 251-254
-
-
Helming, K.C.1
Wang, X.2
Wilson, B.G.3
Vazquez, F.4
Haswell, J.R.5
Manchester, H.E.6
Kim, Y.7
Kryukov, G.V.8
Ghandi, M.9
Aguirre, A.J.10
Jagani, Z.11
Wang, Z.12
Garraway, L.A.13
Hahn, W.C.14
Roberts, C.W.15
-
120
-
-
84865292901
-
Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation
-
Yuan, W., Wu, T., Fu, H., Dai, C., Wu, H., Liu, N., Li, X., Xu, M., Zhang, Z., Niu, T., Han, Z., Chai, J., Zhou, X. J., Gao, S., and Zhu, B. (2012) Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation Science 337, 971-975 10.1126/science.1225237
-
(2012)
Science
, vol.337
, pp. 971-975
-
-
Yuan, W.1
Wu, T.2
Fu, H.3
Dai, C.4
Wu, H.5
Liu, N.6
Li, X.7
Xu, M.8
Zhang, Z.9
Niu, T.10
Han, Z.11
Chai, J.12
Zhou, X.J.13
Gao, S.14
Zhu, B.15
-
121
-
-
84908056869
-
Middle-down hybrid chromatography/tandem mass spectrometry workflow for characterization of combinatorial post-translational modifications in histones
-
Sidoli, S., Schwammle, V., Ruminowicz, C., Hansen, T. A., Wu, X., Helin, K., and Jensen, O. N. (2014) Middle-down hybrid chromatography/tandem mass spectrometry workflow for characterization of combinatorial post-translational modifications in histones Proteomics 14, 2200-2211 10.1002/pmic.201400084
-
(2014)
Proteomics
, vol.14
, pp. 2200-2211
-
-
Sidoli, S.1
Schwammle, V.2
Ruminowicz, C.3
Hansen, T.A.4
Wu, X.5
Helin, K.6
Jensen, O.N.7
-
122
-
-
84902127230
-
Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation
-
Blackledge, N. P., Farcas, A. M., Kondo, T., King, H. W., McGouran, J. F., Hanssen, L. L., Ito, S., Cooper, S., Kondo, K., Koseki, Y., Ishikura, T., Long, H. K., Sheahan, T. W., Brockdorff, N., Kessler, B. M., Koseki, H., and Klose, R. J. (2014) Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation Cell 157, 1445-1459 10.1016/j.cell.2014.05.004
-
(2014)
Cell
, vol.157
, pp. 1445-1459
-
-
Blackledge, N.P.1
Farcas, A.M.2
Kondo, T.3
King, H.W.4
McGouran, J.F.5
Hanssen, L.L.6
Ito, S.7
Cooper, S.8
Kondo, K.9
Koseki, Y.10
Ishikura, T.11
Long, H.K.12
Sheahan, T.W.13
Brockdorff, N.14
Kessler, B.M.15
Koseki, H.16
Klose, R.J.17
-
123
-
-
84902333500
-
Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment
-
Cooper, S., Dienstbier, M., Hassan, R., Schermelleh, L., Sharif, J., Blackledge, N. P., De Marco, V., Elderkin, S., Koseki, H., Klose, R., Heger, A., and Brockdorff, N. (2014) Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment Cell Rep. 7, 1456-1470 10.1016/j.celrep.2014.04.012
-
(2014)
Cell Rep.
, vol.7
, pp. 1456-1470
-
-
Cooper, S.1
Dienstbier, M.2
Hassan, R.3
Schermelleh, L.4
Sharif, J.5
Blackledge, N.P.6
De Marco, V.7
Elderkin, S.8
Koseki, H.9
Klose, R.10
Heger, A.11
Brockdorff, N.12
-
124
-
-
84901987800
-
Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression
-
Kalb, R., Latwiel, S., Baymaz, H. I., Jansen, P. W., Muller, C. W., Vermeulen, M., and Muller, J. (2014) Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression Nat. Struct. Mol. Biol. 21, 569-571 10.1038/nsmb.2833
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 569-571
-
-
Kalb, R.1
Latwiel, S.2
Baymaz, H.I.3
Jansen, P.W.4
Muller, C.W.5
Vermeulen, M.6
Muller, J.7
-
125
-
-
78149285100
-
Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2
-
Chen, S., Bohrer, L. R., Rai, A. N., Pan, Y., Gan, L., Zhou, X., Bagchi, A., Simon, J. A., and Huang, H. (2010) Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2 Nat. Cell Biol. 12, 1108-1114 10.1038/ncb2116
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 1108-1114
-
-
Chen, S.1
Bohrer, L.R.2
Rai, A.N.3
Pan, Y.4
Gan, L.5
Zhou, X.6
Bagchi, A.7
Simon, J.A.8
Huang, H.9
-
126
-
-
78649807567
-
Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA
-
Kaneko, S., Li, G., Son, J., Xu, C. F., Margueron, R., Neubert, T. A., and Reinberg, D. (2010) Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA Genes Dev. 24, 2615-2620 10.1101/gad.1983810
-
(2010)
Genes Dev.
, vol.24
, pp. 2615-2620
-
-
Kaneko, S.1
Li, G.2
Son, J.3
Xu, C.F.4
Margueron, R.5
Neubert, T.A.6
Reinberg, D.7
-
127
-
-
7544230144
-
The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
-
Caretti, G., Di Padova, M., Micales, B., Lyons, G. E., and Sartorelli, V. (2004) The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation Genes Dev. 18, 2627-2638 10.1101/gad.1241904
-
(2004)
Genes Dev.
, vol.18
, pp. 2627-2638
-
-
Caretti, G.1
Di Padova, M.2
Micales, B.3
Lyons, G.E.4
Sartorelli, V.5
-
128
-
-
77957357566
-
TNF/p38alpha/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration
-
Palacios, D., Mozzetta, C., Consalvi, S., Caretti, G., Saccone, V., Proserpio, V., Marquez, V. E., Valente, S., Mai, A., Forcales, S. V., Sartorelli, V., and Puri, P. L. (2010) TNF/p38alpha/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration Cell Stem Cell 7, 455-469 10.1016/j.stem.2010.08.013
-
(2010)
Cell Stem Cell
, vol.7
, pp. 455-469
-
-
Palacios, D.1
Mozzetta, C.2
Consalvi, S.3
Caretti, G.4
Saccone, V.5
Proserpio, V.6
Marquez, V.E.7
Valente, S.8
Mai, A.9
Forcales, S.V.10
Sartorelli, V.11
Puri, P.L.12
-
129
-
-
78650511231
-
CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells
-
Wei, Y., Chen, Y. H., Li, L. Y., Lang, J., Yeh, S. P., Shi, B., Yang, C. C., Yang, J. Y., Lin, C. Y., Lai, C. C., and Hung, M. C. (2011) CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells Nat. Cell Biol. 13, 87-94 10.1038/ncb2139
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 87-94
-
-
Wei, Y.1
Chen, Y.H.2
Li, L.Y.3
Lang, J.4
Yeh, S.P.5
Shi, B.6
Yang, C.C.7
Yang, J.Y.8
Lin, C.Y.9
Lai, C.C.10
Hung, M.C.11
-
130
-
-
80051496158
-
Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability
-
Wu, S. C. and Zhang, Y. (2011) Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability J. Biol. Chem. 286, 28511-28519 10.1074/jbc.M111.240515
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28511-28519
-
-
Wu, S.C.1
Zhang, Y.2
-
131
-
-
26844520965
-
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
-
Cha, T. L., Zhou, B. P., Xia, W., Wu, Y., Yang, C. C., Chen, C. T., Ping, B., Otte, A. P., and Hung, M. C. (2005) Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3 Science 310, 306-310 10.1126/science.1118947
-
(2005)
Science
, vol.310
, pp. 306-310
-
-
Cha, T.L.1
Zhou, B.P.2
Xia, W.3
Wu, Y.4
Yang, C.C.5
Chen, C.T.6
Ping, B.7
Otte, A.P.8
Hung, M.C.9
-
132
-
-
84871052080
-
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent
-
Xu, K., Wu, Z. J., Groner, A. C., He, H. H., Cai, C., Lis, R. T., Wu, X., Stack, E. C., Loda, M., Liu, T., Xu, H., Cato, L., Thornton, J. E., Gregory, R. I., Morrissey, C., Vessella, R. L., Montironi, R., Magi-Galluzzi, C., Kantoff, P. W., Balk, S. P., Liu, X. S., and Brown, M. (2012) EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent Science 338, 1465-1469 10.1126/science.1227604
-
(2012)
Science
, vol.338
, pp. 1465-1469
-
-
Xu, K.1
Wu, Z.J.2
Groner, A.C.3
He, H.H.4
Cai, C.5
Lis, R.T.6
Wu, X.7
Stack, E.C.8
Loda, M.9
Liu, T.10
Xu, H.11
Cato, L.12
Thornton, J.E.13
Gregory, R.I.14
Morrissey, C.15
Vessella, R.L.16
Montironi, R.17
Magi-Galluzzi, C.18
Kantoff, P.W.19
Balk, S.P.20
Liu, X.S.21
Brown, M.22
more..
-
133
-
-
79151477313
-
Inactive yet indispensable: The tale of Jarid2
-
Landeira, D. and Fisher, A. G. (2011) Inactive yet indispensable: the tale of Jarid2 Trends Cell Biol. 21, 74-80 10.1016/j.tcb.2010.10.004
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 74-80
-
-
Landeira, D.1
Fisher, A.G.2
-
134
-
-
84892889808
-
Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin
-
Kaneko, S., Bonasio, R., Saldana-Meyer, R., Yoshida, T., Son, J., Nishino, K., Umezawa, A., and Reinberg, D. (2014) Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin Mol. Cell 53, 290-300 10.1016/j.molcel.2013.11.012
-
(2014)
Mol. Cell
, vol.53
, pp. 290-300
-
-
Kaneko, S.1
Bonasio, R.2
Saldana-Meyer, R.3
Yoshida, T.4
Son, J.5
Nishino, K.6
Umezawa, A.7
Reinberg, D.8
-
135
-
-
84870833161
-
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity
-
Ballare, C., Lange, M., Lapinaite, A., Martin, G. M., Morey, L., Pascual, G., Liefke, R., Simon, B., Shi, Y., Gozani, O., Carlomagno, T., Benitah, S. A., and Di Croce, L. (2012) Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity Nat. Struct. Mol. Biol. 19, 1257-1265 10.1038/nsmb.2434
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 1257-1265
-
-
Ballare, C.1
Lange, M.2
Lapinaite, A.3
Martin, G.M.4
Morey, L.5
Pascual, G.6
Liefke, R.7
Simon, B.8
Shi, Y.9
Gozani, O.10
Carlomagno, T.11
Benitah, S.A.12
Di Croce, L.13
-
136
-
-
84870825642
-
Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation
-
Brien, G. L., Gambero, G., O'Connell, D. J., Jerman, E., Turner, S. A., Egan, C. M., Dunne, E. J., Jurgens, M. C., Wynne, K., Piao, L., Lohan, A. J., Ferguson, N., Shi, X., Sinha, K. M., Loftus, B. J., Cagney, G., and Bracken, A. P. (2012) Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation Nat. Struct. Mol. Biol. 19, 1273-1281 10.1038/nsmb.2449
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 1273-1281
-
-
Brien, G.L.1
Gambero, G.2
O'Connell, D.J.3
Jerman, E.4
Turner, S.A.5
Egan, C.M.6
Dunne, E.J.7
Jurgens, M.C.8
Wynne, K.9
Piao, L.10
Lohan, A.J.11
Ferguson, N.12
Shi, X.13
Sinha, K.M.14
Loftus, B.J.15
Cagney, G.16
Bracken, A.P.17
-
137
-
-
84873417354
-
An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting
-
Cai, L., Rothbart, S. B., Lu, R., Xu, B., Chen, W. Y., Tripathy, A., Rockowitz, S., Zheng, D., Patel, D. J., Allis, C. D., Strahl, B. D., Song, J., and Wang, G. G. (2013) An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting Mol. Cell 49, 571-582 10.1016/j.molcel.2012.11.026
-
(2013)
Mol. Cell
, vol.49
, pp. 571-582
-
-
Cai, L.1
Rothbart, S.B.2
Lu, R.3
Xu, B.4
Chen, W.Y.5
Tripathy, A.6
Rockowitz, S.7
Zheng, D.8
Patel, D.J.9
Allis, C.D.10
Strahl, B.D.11
Song, J.12
Wang, G.G.13
-
138
-
-
84872347438
-
Tudor domains of the PRC2 components PHF1 and PHF19 selectively bind to histone H3K36me3
-
Qin, S., Guo, Y., Xu, C., Bian, C., Fu, M., Gong, S., and Min, J. (2013) Tudor domains of the PRC2 components PHF1 and PHF19 selectively bind to histone H3K36me3 Biochem. Biophys. Res. Commun. 430, 547-553 10.1016/j.bbrc.2012.11.116
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.430
, pp. 547-553
-
-
Qin, S.1
Guo, Y.2
Xu, C.3
Bian, C.4
Fu, M.5
Gong, S.6
Min, J.7
-
139
-
-
40749126138
-
Role of hPHF1 in H3K27 methylation and Hox gene silencing
-
Cao, R., Wang, H., He, J., Erdjument-Bromage, H., Tempst, P., and Zhang, Y. (2008) Role of hPHF1 in H3K27 methylation and Hox gene silencing Mol. Cell. Biol. 28, 1862-1872 10.1128/MCB.01589-07
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 1862-1872
-
-
Cao, R.1
Wang, H.2
He, J.3
Erdjument-Bromage, H.4
Tempst, P.5
Zhang, Y.6
-
140
-
-
75349104610
-
Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation
-
Walker, E., Chang, W. Y., Hunkapiller, J., Cagney, G., Garcha, K., Torchia, J., Krogan, N. J., Reiter, J. F., and Stanford, W. L. (2010) Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation Cell Stem Cell 6, 153-166 10.1016/j.stem.2009.12.014
-
(2010)
Cell Stem Cell
, vol.6
, pp. 153-166
-
-
Walker, E.1
Chang, W.Y.2
Hunkapiller, J.3
Cagney, G.4
Garcha, K.5
Torchia, J.6
Krogan, N.J.7
Reiter, J.F.8
Stanford, W.L.9
-
141
-
-
79955441928
-
Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells
-
Casanova, M., Preissner, T., Cerase, A., Poot, R., Yamada, D., Li, X., Appanah, R., Bezstarosti, K., Demmers, J., Koseki, H., and Brockdorff, N. (2011) Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells Development 138, 1471-1482 10.1242/dev.053652
-
(2011)
Development
, vol.138
, pp. 1471-1482
-
-
Casanova, M.1
Preissner, T.2
Cerase, A.3
Poot, R.4
Yamada, D.5
Li, X.6
Appanah, R.7
Bezstarosti, K.8
Demmers, J.9
Koseki, H.10
Brockdorff, N.11
-
142
-
-
78751537712
-
Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes
-
Li, X., Isono, K., Yamada, D., Endo, T. A., Endoh, M., Shinga, J., Mizutani-Koseki, Y., Otte, A. P., Casanova, M., Kitamura, H., Kamijo, T., Sharif, J., Ohara, O., Toyada, T., Bernstein, B. E., Brockdorff, N., and Koseki, H. (2011) Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes Mol. Cell. Biol. 31, 351-364 10.1128/MCB.00259-10
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 351-364
-
-
Li, X.1
Isono, K.2
Yamada, D.3
Endo, T.A.4
Endoh, M.5
Shinga, J.6
Mizutani-Koseki, Y.7
Otte, A.P.8
Casanova, M.9
Kitamura, H.10
Kamijo, T.11
Sharif, J.12
Ohara, O.13
Toyada, T.14
Bernstein, B.E.15
Brockdorff, N.16
Koseki, H.17
-
143
-
-
79952135845
-
PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming
-
Zhang, Z., Jones, A., Sun, C. W., Li, C., Chang, C. W., Joo, H. Y., Dai, Q., Mysliwiec, M. R., Wu, L. C., Guo, Y., Yang, W., Liu, K., Pawlik, K. M., Erdjument-Bromage, H., Tempst, P., Lee, Y., Min, J., Townes, T. M., and Wang, H. (2011) PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming Stem Cells 29, 229-240 10.1002/stem.578
-
(2011)
Stem Cells
, vol.29
, pp. 229-240
-
-
Zhang, Z.1
Jones, A.2
Sun, C.W.3
Li, C.4
Chang, C.W.5
Joo, H.Y.6
Dai, Q.7
Mysliwiec, M.R.8
Wu, L.C.9
Guo, Y.10
Yang, W.11
Liu, K.12
Pawlik, K.M.13
Erdjument-Bromage, H.14
Tempst, P.15
Lee, Y.16
Min, J.17
Townes, T.M.18
Wang, H.19
-
144
-
-
55349109963
-
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome
-
Zhao, J., Sun, B. K., Erwin, J. A., Song, J. J., and Lee, J. T. (2008) Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome Science 322, 750-756 10.1126/science.1163045
-
(2008)
Science
, vol.322
, pp. 750-756
-
-
Zhao, J.1
Sun, B.K.2
Erwin, J.A.3
Song, J.J.4
Lee, J.T.5
-
145
-
-
84892866184
-
Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome
-
da Rocha, S. T., Boeva, V., Escamilla-Del-Arenal, M., Ancelin, K., Granier, C., Matias, N. R., Sanulli, S., Chow, J., Schulz, E., Picard, C., Kaneko, S., Helin, K., Reinberg, D., Stewart, A. F., Wutz, A., Margueron, R., and Heard, E. (2014) Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome Mol. Cell 53, 301-316 10.1016/j.molcel.2014.01.002
-
(2014)
Mol. Cell
, vol.53
, pp. 301-316
-
-
Da Rocha, S.T.1
Boeva, V.2
Escamilla-Del-Arenal, M.3
Ancelin, K.4
Granier, C.5
Matias, N.R.6
Sanulli, S.7
Chow, J.8
Schulz, E.9
Picard, C.10
Kaneko, S.11
Helin, K.12
Reinberg, D.13
Stewart, A.F.14
Wutz, A.15
Margueron, R.16
Heard, E.17
-
146
-
-
34250729138
-
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
-
Rinn, J. L., Kertesz, M., Wang, J. K., Squazzo, S. L., Xu, X., Brugmann, S. A., Goodnough, L. H., Helms, J. A., Farnham, P. J., Segal, E., and Chang, H. Y. (2007) Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs Cell 129, 1311-1323 10.1016/j.cell.2007.05.022
-
(2007)
Cell
, vol.129
, pp. 1311-1323
-
-
Rinn, J.L.1
Kertesz, M.2
Wang, J.K.3
Squazzo, S.L.4
Xu, X.5
Brugmann, S.A.6
Goodnough, L.H.7
Helms, J.A.8
Farnham, P.J.9
Segal, E.10
Chang, H.Y.11
-
147
-
-
77954572735
-
Long noncoding RNA as modular scaffold of histone modification complexes
-
Tsai, M. C., Manor, O., Wan, Y., Mosammaparast, N., Wang, J. K., Lan, F., Shi, Y., Segal, E., and Chang, H. Y. (2010) Long noncoding RNA as modular scaffold of histone modification complexes Science 329, 689-693 10.1126/science.1192002
-
(2010)
Science
, vol.329
, pp. 689-693
-
-
Tsai, M.C.1
Manor, O.2
Wan, Y.3
Mosammaparast, N.4
Wang, J.K.5
Lan, F.6
Shi, Y.7
Segal, E.8
Chang, H.Y.9
-
148
-
-
78650253763
-
Genome-wide identification of polycomb-associated RNAs by RIP-seq
-
Zhao, J., Ohsumi, T. K., Kung, J. T., Ogawa, Y., Grau, D. J., Sarma, K., Song, J. J., Kingston, R. E., Borowsky, M., and Lee, J. T. (2010) Genome-wide identification of polycomb-associated RNAs by RIP-seq Mol. Cell 40, 939-953 10.1016/j.molcel.2010.12.011
-
(2010)
Mol. Cell
, vol.40
, pp. 939-953
-
-
Zhao, J.1
Ohsumi, T.K.2
Kung, J.T.3
Ogawa, Y.4
Grau, D.J.5
Sarma, K.6
Song, J.J.7
Kingston, R.E.8
Borowsky, M.9
Lee, J.T.10
-
149
-
-
84887419464
-
Promiscuous RNA binding by Polycomb repressive complex 2
-
Davidovich, C., Zheng, L., Goodrich, K. J., and Cech, T. R. (2013) Promiscuous RNA binding by Polycomb repressive complex 2 Nat. Struct. Mol. Biol. 20, 1250-1257 10.1038/nsmb.2679
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1250-1257
-
-
Davidovich, C.1
Zheng, L.2
Goodrich, K.J.3
Cech, T.R.4
-
150
-
-
84887460647
-
PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells
-
Kaneko, S., Son, J., Shen, S. S., Reinberg, D., and Bonasio, R. (2013) PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells Nat. Struct. Mol. Biol. 20, 1258-1264 10.1038/nsmb.2700
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1258-1264
-
-
Kaneko, S.1
Son, J.2
Shen, S.S.3
Reinberg, D.4
Bonasio, R.5
-
151
-
-
84904507962
-
Regulatory interactions between RNA and polycomb repressive complex 2
-
Cifuentes-Rojas, C., Hernandez, A. J., Sarma, K., and Lee, J. T. (2014) Regulatory interactions between RNA and polycomb repressive complex 2 Mol. Cell 55, 171-185 10.1016/j.molcel.2014.05.009
-
(2014)
Mol. Cell
, vol.55
, pp. 171-185
-
-
Cifuentes-Rojas, C.1
Hernandez, A.J.2
Sarma, K.3
Lee, J.T.4
|