-
1
-
-
84863621527
-
Cancer epigenetics: From mechanism to therapy
-
M. A. Dawson, T. Kouzarides, Cancer epigenetics: From mechanism to therapy. Cell 150, 12-27 (2012).
-
(2012)
Cell
, vol.150
, pp. 12-27
-
-
Dawson, M.A.1
Kouzarides, T.2
-
2
-
-
84961288162
-
Chromatin signatures of cancer
-
M. A. Morgan, A. Shilatifard, Chromatin signatures of cancer. Genes Dev. 29, 238-249 (2015).
-
(2015)
Genes Dev.
, vol.29
, pp. 238-249
-
-
Morgan, M.A.1
Shilatifard, A.2
-
3
-
-
84872810488
-
The spectrum of SWI/SNF mutations, ubiquitous in human cancers
-
A. H. Shain, J. R. Pollack, The spectrum of SWI/SNF mutations, ubiquitous in human cancers. PLOS One 8, e55119 (2013).
-
(2013)
PLOS One
, vol.8
, pp. e55119
-
-
Shain, A.H.1
Pollack, J.R.2
-
4
-
-
84878745222
-
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
-
C. Kadoch, D. C. Hargreaves, C. Hodges, L. Elias, L. Ho, J. Ranish, G. R. Crabtree, Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. Nat. Genet. 45, 592-601 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 592-601
-
-
Kadoch, C.1
Hargreaves, D.C.2
Hodges, C.3
Elias, L.4
Ho, L.5
Ranish, J.6
Crabtree, G.R.7
-
5
-
-
0021659727
-
Five SWI genes are required for expression of the HO gene in yeast
-
M. Stern, R. Jensen, I. Herskowitz, Five SWI genes are required for expression of the HO gene in yeast. J. Mol. Biol 178, 853-868 (1984).
-
(1984)
J. Mol. Biol
, vol.178
, pp. 853-868
-
-
Stern, M.1
Jensen, R.2
Herskowitz, I.3
-
6
-
-
0021715020
-
Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae
-
L. Neigeborn, M. Carlson, Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae. Genetics 108, 845-858 (1984).
-
(1984)
Genetics
, vol.108
, pp. 845-858
-
-
Neigeborn, L.1
Carlson, M.2
-
7
-
-
0026584855
-
Characterization of the yeast SWII, SWI2, and SWI3 genes, which encode a global activator of transcription
-
C L. Peterson, I. Herskowitz, Characterization of the yeast SWII, SWI2, and SWI3 genes, which encode a global activator of transcription. Cell 68, 573-583 (1992).
-
(1992)
Cell
, vol.68
, pp. 573-583
-
-
Peterson, C.L.1
Herskowitz, I.2
-
8
-
-
0026580006
-
Brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWi2
-
J. W. Tamkun R Deuring, M. P. Scott, M. Kissinger, A. M. Pattatucci, T. C Kaufman, J. A Kennison, brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWi2. Cell 68, 561 (1992).
-
(1992)
Cell
, vol.68
, pp. 561
-
-
Tamkun Deuring R, J.W.1
Scott, M.P.2
Kissinger, M.3
Pattatucci, A.M.4
Kaufman, T.C.5
Kennison, J.A.6
-
9
-
-
0345046221
-
Dosage-dependent modifiers of polycomb and antennapedia mutations in
-
J. A Kennison, J. W. Tamkun, Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila. Proc. Natl. Acad. Sci. USA. 85, 8136-8140 (1988).
-
(1988)
Drosophila. Proc. Natl. Acad. Sci. USA.
, vol.85
, pp. 8136-8140
-
-
Kennison, J.A.1
Tamkun, J.W.2
-
10
-
-
0035826798
-
The HMG-domain protein BAP111 is important for the function of the BRM chromatin-remodeling complex in vivo
-
O. Papoulas, G. Daubresse, J. A. Armstrong, J. Jin, M. P. Scott, J. W. Tamkun, The HMG-domain protein BAP111 is important for the function of the BRM chromatin-remodeling complex in vivo. Proc. Natl. Acad. Sci. USA. 98, 5728-5733 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA.
, vol.98
, pp. 5728-5733
-
-
Papoulas, O.1
Daubresse, G.2
Armstrong, J.A.3
Jin, J.4
Scott, M.P.5
Tamkun, J.W.6
-
11
-
-
79961002967
-
EsBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function
-
L. Ho, E. L. Miller, J. L. Ronan, W. Q. Ho, R. Jothi, G. R. Crabtree, esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function. Nat. Cell Biol. 13, 903-913 (2011).
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 903-913
-
-
Ho, L.1
Miller, E.L.2
Ronan, J.L.3
Ho, W.Q.4
Jothi, R.5
Crabtree, G.R.6
-
12
-
-
0035818465
-
COMPASS: A complex of proteins associated with a trithorax-related SET domain protein
-
T. Miller, N. J. Krogan, J. Dover, H. Erdjument-Bromage, P. Tempst, M. Johnston, J. F. Greenblatt, A. Shilatifard, COMPASS: A complex of proteins associated with a trithorax-related SET domain protein. Proc. Natl. Acad. Sci. USA. 98, 12902-12907 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA.
, vol.98
, pp. 12902-12907
-
-
Miller, T.1
Krogan, N.J.2
Dover, J.3
Erdjument-Bromage, H.4
Tempst, P.5
Johnston, M.6
Greenblatt, J.F.7
Shilatifard, A.8
-
13
-
-
84920939145
-
Product binding enforces the genomic specificity of a yeast polycomb repressive complex
-
P. A. Dumesic, C. M. Homer, J. J. Moresco, L. R. Pack, E. K. Shanle, S. M. Coyle, B. D. Strahl, D. G. Fujimori, J. R. Yates III, H. D. Madhani, Product binding enforces the genomic specificity of a yeast polycomb repressive complex. Cell 160, 204-218 (2015).
-
(2015)
Cell
, vol.160
, pp. 204-218
-
-
Dumesic, P.A.1
Homer, C.M.2
Moresco, J.J.3
Pack, L.R.4
Shanle, E.K.5
Coyle, S.M.6
Strahl, B.D.7
Fujimori, D.G.8
Yates, J.R.9
Madhani, H.D.10
-
14
-
-
0027493251
-
BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription
-
P. A. Khavari, C. L. Peterson, J. W. Tamkun, D. B. Mendel, G. R. Crabtree, BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature 366, 170-174 (1993).
-
(1993)
Nature
, vol.366
, pp. 170-174
-
-
Khavari, P.A.1
Peterson, C.L.2
Tamkun, J.W.3
Mendel, D.B.4
Crabtree, G.R.5
-
15
-
-
0031906816
-
Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes
-
W. Wang, T. Chi, Y. Xue, S. Zhou, A. Kuo, G. R. Crabtree, Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes. Proc. Natl. Acad. Sci. U.S.A. 95, 492-498 (1998).
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 492-498
-
-
Wang, W.1
Chi, T.2
Xue, Y.3
Zhou, S.4
Kuo, A.5
Crabtree, G.R.6
-
16
-
-
10144228410
-
Purification and biochemical heterogeneity of the mammalian SWI-SNF complex
-
W. Wang, J. Cote, Y. Xue, S. Zhou, P. A. Khavari, S. R. Biggar, C. Muchardt, G. V. Kalpana, S. P. Goff, M. Yaniv, J. L. Workman, G. R. Crabtree, Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. Embo J 15, 5370-5382 (1996).
-
(1996)
Embo J
, vol.15
, pp. 5370-5382
-
-
Wang, W.1
Cote, J.2
Xue, Y.3
Zhou, S.4
Khavari, P.A.5
Biggar, S.R.6
Muchardt, C.7
Kalpana, G.V.8
Goff, S.P.9
Yaniv, M.10
Workman, J.L.11
Crabtree, G.R.12
-
17
-
-
0029787059
-
Diversity and specialization of mammalian SWI/SNF complexes
-
W. Wang, Y. Xue, S. Zhou, A. Kuo, B. R. Cairns, G. R. Crabtree, Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev. 10, 2117-2130 (1996).
-
(1996)
Genes Dev.
, vol.10
, pp. 2117-2130
-
-
Wang, W.1
Xue, Y.2
Zhou, S.3
Kuo, A.4
Cairns, B.R.5
Crabtree, G.R.6
-
18
-
-
0027434083
-
A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor
-
C. Muchardt, M. Yaniv, A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. EMBO J. 12, 4279-4290 (1993).
-
(1993)
EMBO J.
, vol.12
, pp. 4279-4290
-
-
Muchardt, C.1
Yaniv, M.2
-
19
-
-
34447249019
-
An essential switch in subunit composition of a chromatin remodeling complex during neural development
-
J. Lessard, J. I. Wu, J. A. Ranish, M. Wan, M. M. Winslow, B. T. Staahl, H. Wu, R. Aebersold, I. A. Graef, G. R. Crabtree, An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron 55, 201-215 (2007).
-
(2007)
Neuron
, vol.55
, pp. 201-215
-
-
Lessard, J.1
Wu, J.I.2
Ranish, J.A.3
Wan, M.4
Winslow, M.M.5
Staahl, B.T.6
Wu, H.7
Aebersold, R.8
Graef, I.A.9
Crabtree, G.R.10
-
20
-
-
84879136007
-
Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways
-
B. T. Staahl, J. Tang, W. Wu, A. Sun, A. D. Gitler, A. S. Yoo, G. R. Crabtree, Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways. J. Neurosci. 33, 10348-10361 (2013).
-
(2013)
J. Neurosci.
, vol.33
, pp. 10348-10361
-
-
Staahl, B.T.1
Tang, J.2
Wu, W.3
Sun, A.4
Gitler, A.D.5
Yoo, A.S.6
Crabtree, G.R.7
-
21
-
-
0030447612
-
RSC, an essential, abundant chromatin-remodeling complex
-
B. R. Cairns, Y. Lorch, Y. Li, M. Zhang, L. Lacomis, H. Erdjument-Bromage, P. Tempst, J. Du, B. Laurent, R. D. Kornberg, RSC, an essential, abundant chromatin-remodeling complex. Cell 87, 1249-1260 (1996).
-
(1996)
Cell
, vol.87
, pp. 1249-1260
-
-
Cairns, B.R.1
Lorch, Y.2
Li, Y.3
Zhang, M.4
Lacomis, L.5
Erdjument-Bromage, H.6
Tempst, P.7
Du, J.8
Laurent, B.9
Kornberg, R.D.10
-
22
-
-
0034601464
-
A chromatin remodelling complex involved in transcription and DNA processing
-
X. Shen, G. Mizuguchi, A. Hamiche, C. Wu, A chromatin remodelling complex involved in transcription and DNA processing. Nature 406, 541-544 (2000).
-
(2000)
Nature
, vol.406
, pp. 541-544
-
-
Shen, X.1
Mizuguchi, G.2
Hamiche, A.3
Wu, C.4
-
23
-
-
0037414839
-
Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates
-
X. Shen, H. Xiao, R. Ranallo, W. H. Wu, C Wu, Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates. Science 299, 112-114 (2003).
-
(2003)
Science
, vol.299
, pp. 112-114
-
-
Shen, X.1
Xiao, H.2
Ranallo, R.3
Wu, W.H.4
Wu, C.5
-
24
-
-
84925433120
-
INO80-C and SWR-C: Guardians of the genome
-
C. B. Gerhold, M. H. Hauer, S. M. Gasser, INO80-C and SWR-C: Guardians of the Genome. J. Mol. Biol. 427, 637-651 (2014).
-
(2014)
J. Mol. Biol.
, vol.427
, pp. 637-651
-
-
Gerhold, C.B.1
Hauer, M.H.2
Gasser, S.M.3
-
25
-
-
0028093378
-
Nucleosome disruption and enhancement of activator binding bya human SW1/SNF complex
-
H. Kwon, A. N. Imbalzano, P. A. Khavari, R. E. Kingston, M. R. Green, Nucleosome disruption and enhancement of activator binding bya human SW1/SNF complex. Nature 370,477-481 (1994).
-
(1994)
Nature
, vol.370
, pp. 477-481
-
-
Kwon, H.1
Imbalzano, A.N.2
Khavari, P.A.3
Kingston, R.E.4
Green, M.R.5
-
26
-
-
0028068714
-
Facilitated binding of TATA-binding protein to nucleosomal DNA
-
A. N. Imbalzano, H. Kwon, M. R. Green, R. E. Kingston, Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature 370, 481-485 (1994).
-
(1994)
Nature
, vol.370
, pp. 481-485
-
-
Imbalzano, A.N.1
Kwon, H.2
Green, M.R.3
Kingston, R.E.4
-
27
-
-
67650725820
-
The biology of chromatin remodeling complexes
-
C. R. Clapier, B. R. Cairns, The biology of chromatin remodeling complexes. Annu. Rev. Biochem. 78, 273-304 (2009).
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 273-304
-
-
Clapier, C.R.1
Cairns, B.R.2
-
28
-
-
84881166117
-
Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes
-
G. J. Narlikar, R. Sundaramoorthy, T. Owen-Hughes, Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes. Cell 154, 490-503 (2013).
-
(2013)
Cell
, vol.154
, pp. 490-503
-
-
Narlikar, G.J.1
Sundaramoorthy, R.2
Owen-Hughes, T.3
-
29
-
-
0033617334
-
Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter
-
M. P. Cosma, T. Tanaka, K. Nasmyth, Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter. Cell 97, 299-311 (1999).
-
(1999)
Cell
, vol.97
, pp. 299-311
-
-
Cosma, M.P.1
Tanaka, T.2
Nasmyth, K.3
-
30
-
-
84873595705
-
ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4
-
X. Bao, J. Tang, V. Lopez-Pajares, S. Tao, K. Qu, G. R. Crabtree, P. A. Khavari, ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4. Cell Stem Cell 12, 193-203 (2013).
-
(2013)
Cell Stem Cell
, vol.12
, pp. 193-203
-
-
Bao, X.1
Tang, J.2
Lopez-Pajares, V.3
Tao, S.4
Qu, K.5
Crabtree, G.R.6
Khavari, P.A.7
-
31
-
-
67949083572
-
MicroRNA-mediated switching of chromatin-remodelling complexes in neural development
-
A. S. Yoo, B. T. Staahl, L. Chen, G. R. Crabtree, MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature 460, 642-646 (2009).
-
(2009)
Nature
, vol.460
, pp. 642-646
-
-
Yoo, A.S.1
Staahl, B.T.2
Chen, L.3
Crabtree, G.R.4
-
32
-
-
65249180173
-
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
-
L. Ho, J. L. Ronan, J. Wu, B. T. Staahl, L. Chen, A. Kuo, J. Lessard, A. I. Nesvizhskii, J. Ranish, G. R. Crabtree, An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proc. Natl. Acad. Sci. USA. 106, 5181-5186 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA.
, vol.106
, pp. 5181-5186
-
-
Ho, L.1
Ronan, J.L.2
Wu, J.3
Staahl, B.T.4
Chen, L.5
Kuo, A.6
Lessard, J.7
Nesvizhskii, A.I.8
Ranish, J.9
Crabtree, G.R.10
-
33
-
-
84870728704
-
The BAF53a subunit of SWI/SNF-like BAF complexes is essential for hemopoietic stem eel function
-
V. Krasteva, M. Buscarlet, A. Diaz-Tellez, M. A. Bernard, G. R. Crabtree, J. A. Lessard, The BAF53a subunit of SWI/SNF-like BAF complexes is essential for hemopoietic stem eel function. Blood 120, 4720-4732 (2012).
-
(2012)
Blood
, vol.120
, pp. 4720-4732
-
-
Krasteva, V.1
Buscarlet, M.2
Diaz-Tellez, A.3
Bernard, M.A.4
Crabtree, G.R.5
Lessard, J.A.6
-
34
-
-
33749016462
-
Targeted disruption of the synovial sarcoma-associated SSI8 gene causes early embryonic lethality and affects PPARBP expression
-
D. R. de Bruijn, W. J. Peters, S. M. Chuva de Sousa Lopes, A. H. van Dijk, M. P. Willemse, R. Pfundt, P. de Boer, A. Geurts van Kessel, Targeted disruption of the synovial sarcoma-associated SSI8 gene causes early embryonic lethality and affects PPARBP expression. Hum. Mol. Genet. 15, 2936-2944 (2006).
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 2936-2944
-
-
De Bruijn, D.R.1
Peters, W.J.2
De Chuva Lopes Sousa, S.M.3
Van Dijk, A.H.4
Willemse, M.P.5
Pfundt, R.6
De Boer, P.7
Van Kessel Geurts, A.8
-
35
-
-
84923102594
-
Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling
-
R. L. Chandler, J. S. Damrauer, J. R. Raab, J. C. Schisler, M. D. Wilkerson, J. P. Didion, J. Starmer, D. Serber, D. Yee, J. Xiong, D. B. Darr, F. Pardo-Manuel de Villena, W. Y. Kim, T. Magnuson, Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling. Nat. Commun. 6, 6118 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 6118
-
-
Chandler, R.L.1
Damrauer, J.S.2
Raab, J.R.3
Schisler, J.C.4
Wilkerson, M.D.5
Didion, J.P.6
Starmer, J.7
Serber, D.8
Yee, D.9
Xiong, J.10
Darr, D.B.11
De Villena Pardo-Manuel, F.12
Kim, W.Y.13
Magnuson, T.14
-
36
-
-
84875727068
-
Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma
-
C. Kadoch, G. R. Crabtree, Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Cell 153, 71-85 (2013).
-
(2013)
Cell
, vol.153
, pp. 71-85
-
-
Kadoch, C.1
Crabtree, G.R.2
-
37
-
-
77953727663
-
Chromatin-remodeling components of the BAF complex facilitate reprogram-ming
-
N. Singhal, J. Graumann, G. Wu, M. J. Arauzo-Bravo, D. W. Han, B. Greber, L. Gentile, M. Mann, H. R. Scholer, Chromatin-remodeling components of the BAF complex facilitate reprogram-ming. Cell 141, 943-955 (2011).
-
(2011)
Cell
, vol.141
, pp. 943-955
-
-
Singhal, N.1
Graumann, J.2
Wu, G.3
Arauzo-Bravo, M.J.4
Han, D.W.5
Greber, B.6
Gentile, L.7
Mann, M.8
Scholer, H.R.9
-
38
-
-
80051684096
-
MicroRNA-mediated conversion of human fibroblasts to neurons
-
A. S. Yoo, A. X. Sun, L. Li, A. Shcheglovitov, T. Portmann, Y. Li, C. Lee-Messer, R. E. Dolmetsch, R. W. Tsien, G. R. Crabtree, MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 476, 228-231 (2011).
-
(2011)
Nature
, vol.476
, pp. 228-231
-
-
Yoo, A.S.1
Sun, A.X.2
Li, L.3
Shcheglovitov, A.4
Portmann, T.5
Li, Y.6
Lee-Messer, C.7
Dolmetsch, R.E.8
Tsien, R.W.9
Crabtree, G.R.10
-
39
-
-
79351469421
-
The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting
-
J. S. Tea, L. Luo, The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting. Neural Dev. 6, 5 (2011) .
-
(2011)
Neural Dev.
, vol.6
, pp. 5
-
-
Tea, J.S.1
Luo, L.2
-
40
-
-
8544270889
-
Baf60c is essential for function of BAF chromatin remodelling complexes in heart development
-
H. Lickert, J. K. Takeuchi, B. I. Von, J. R. Walls, F. McAuliffe, S. L. Adamson, R. M. Henkelman, J. L. Wrana, J. Rossant, B. G. Bruneau, Baf60c is essential for function of BAF chromatin remodelling complexes in heart development. Nature 432, 107-112 (2004).
-
(2004)
Nature
, vol.432
, pp. 107-112
-
-
Lickert, H.1
Takeuchi, J.K.2
Von, B.I.3
Walls, J.R.4
McAuliffe, F.5
Adamson, S.L.6
Henkelman, R.M.7
Wrana, J.L.8
Rossant, J.9
Bruneau, B.G.10
-
41
-
-
0035134330
-
Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation
-
I. L. de la Serna, K. A. Carlson, A. N. Imbalzano, Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation. Nat. Genet. 27, 187-190 (2001).
-
(2001)
Nat. Genet.
, vol.27
, pp. 187-190
-
-
De La Serna, I.L.1
Carlson, K.A.2
Imbalzano, A.N.3
-
42
-
-
0033636901
-
Components of the SWI/SNF complex are required for asymmetric cell division in C. Eiegans
-
H. Sawa, H. Kouike, H. Okano, Components of the SWI/SNF complex are required for asymmetric cell division in C. eiegans. Mol. Ceil 6, 617-624 (2000).
-
(2000)
Mol. Ceil
, vol.6
, pp. 617-624
-
-
Sawa, H.1
Kouike, H.2
Okano, H.3
-
43
-
-
84862830331
-
Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome
-
G. W. Santen, E. Aten, Y. Sun, R. Almomani, C. Gilissen, M. Nielsen, S. G. Kant, I. N. Snoeck, E. A. Peeters, Y. Hilhorst-Hofstee, M. W. Wessels, N. S. den Hollander, C. A. Ruivenkamp, G. J. van Ommen, M. H. Breuning, J. T. den Dunnen, A. van Haeringen, M. Kriek, Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome. Nat. Genet. 44, 379-380 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 379-380
-
-
Santen, G.W.1
Aten, E.2
Sun, Y.3
Almomani, R.4
Gilissen, C.5
Nielsen, M.6
Kant, S.G.7
Snoeck, I.N.8
Peeters, E.A.9
Hilhorst-Hofstee, Y.10
Wessels, M.W.11
Den Hollander, N.S.12
Ruivenkamp, C.A.13
Van Ommen, G.J.14
Breuning, M.H.15
Den Dunnen, J.T.16
Van Haeringen, A.17
Kriek, M.18
-
44
-
-
84859427243
-
Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome
-
Y. Tsurusaki, N. Okamoto, H. Ohashi, T. Kosho, Y. Imai, Y. Hibi-Ko, T. Kaname, K. Naritomi, H. Kawame, K. Wakui, Y. Fukushima, T. Homma, M. Kato, Y. Hiraki, T. Yamagata, S. Yano, S. Mizuno, S. Sakazume, T. lshii, T. Nagai, M. Shiina, K. Ogata, T. Ohta, N. Niikawa, S. Miyatake, I. Okada, T. Mizuguchi, H. Doi, H. Saitsu, N. Miyake, N. Matsumoto, Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome. Nat. Genet. 44, 376-378 (2012) .
-
(2012)
Nat. Genet.
, vol.44
, pp. 376-378
-
-
Tsurusaki, Y.1
Okamoto, N.2
Ohashi, H.3
Kosho, T.4
Imai, Y.5
Hibi-Ko, Y.6
Kaname, T.7
Naritomi, K.8
Kawame, H.9
Wakui, K.10
Fukushima, Y.11
Homma, T.12
Kato, M.13
Hiraki, Y.14
Yamagata, T.15
Yano, S.16
Mizuno, S.17
Sakazume, S.18
Lshii, T.19
Nagai, T.20
Shiina, M.21
Ogata, K.22
Ohta, T.23
Niikawa, N.24
Miyatake, S.25
Okada, I.26
Mizuguchi, T.27
Doi, H.28
Saitsu, H.29
Miyake, N.30
Matsumoto, N.31
more..
-
45
-
-
77957731999
-
Frequent mutations of chromatin remodeling gene ARID!A in ovarian clear cell carcinoma
-
S. Jones, T. L. Wang, I. M. Shih, T. L. Mao, K. Nakayama, R. Roden, R. Glas, D. Slamon, L. A. Diaz Jr., B. Vogelstein, K. W. Kinzler, V. E. Velculescu, N. Papadopoulos, Frequent mutations of chromatin remodeling gene ARID!A in ovarian clear cell carcinoma. Science 330, 228-231 (2010).
-
(2010)
Science
, vol.330
, pp. 228-231
-
-
Jones, S.1
Wang, T.L.2
Shih, I.M.3
Mao, T.L.4
Nakayama, K.5
Roden, R.6
Glas, R.7
Slamon, D.8
Diaz, L.A.9
Vogelstein, B.10
Kinzler, K.W.11
Velculescu, V.E.12
Papadopoulos, N.13
-
46
-
-
0015212884
-
Dissociation of rat liver ribosomes to active subunits by urea
-
M. Petermann, A. Pavlovec, Dissociation of rat liver ribosomes to active subunits by urea. Biochemistry 10, 2770-2775 (1971).
-
(1971)
Biochemistry
, vol.10
, pp. 2770-2775
-
-
Petermann, M.1
Pavlovec, A.2
-
47
-
-
0032567080
-
Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling
-
K. Zhao, W. Wang, O. J. Rando, Y. Xue, K. Swiderek, A. Kuo, G. R. Crabtree, Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell 95, 625-636 (1998).
-
(1998)
Cell
, vol.95
, pp. 625-636
-
-
Zhao, K.1
Wang, W.2
Rando, O.J.3
Xue, Y.4
Swiderek, K.5
Kuo, A.6
Crabtree, G.R.7
-
48
-
-
58249086425
-
Understanding the words of chromatin regulation
-
J. I. Wu, J. Lessard, G. R. Crabtree, Understanding the words of chromatin regulation. Cell 136, 200-206 (2009).
-
(2009)
Cell
, vol.136
, pp. 200-206
-
-
Wu, J.I.1
Lessard, J.2
Crabtree, G.R.3
-
49
-
-
34748887795
-
Regulation of dendritic development by neuron-specific chromatin remodeling complexes
-
J. I. Wu, J. Lessard, I. A. Olave, Z. Qiu, A. Ghosh, I. A. Graef, G. R. Crabtree, Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron 56, 94-108 (2007).
-
(2007)
Neuron
, vol.56
, pp. 94-108
-
-
Wu, J.I.1
Lessard, J.2
Olave, I.A.3
Qiu, Z.4
Ghosh, A.5
Graef, I.A.6
Crabtree, G.R.7
-
50
-
-
65249173999
-
An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network
-
L. Ho, R. Jothi, J. L. Ronan, K. Cui, K. Zhao, G. R. Crabtree, An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc. Natl. Acad Sci. U.S.A. 106, 5187-5191 (2009).
-
(2009)
Proc. Natl. Acad Sci. U.S.A.
, vol.106
, pp. 5187-5191
-
-
Ho, L.1
Jothi, R.2
Ronan, J.L.3
Cui, K.4
Zhao, K.5
Crabtree, G.R.6
-
51
-
-
79953737587
-
Diverse roles and interactions of the SWI/SNF chromatin remodeling complex revealed using global approaches
-
G. M. Euskirchen, R. K. Auerbach, E. Davidov, T. A. Gianoulis, G. Zhong, J. Rozowsky, N. Bhardwaj, M. B. Gerstein, M. Snyder, Diverse roles and interactions of the SWI/SNF chromatin remodeling complex revealed using global approaches. PLOS Genet. 7, e1002008 (2011).
-
(2011)
PLOS Genet.
, vol.7
, pp. e1002008
-
-
Euskirchen, G.M.1
Auerbach, R.K.2
Davidov, E.3
Gianoulis, T.A.4
Zhong, G.5
Rozowsky, J.6
Bhardwaj, N.7
Gerstein, M.B.8
Snyder, M.9
-
52
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
A. Rada-lglesias, R. Bajpai, T. Swigut, S. A. Brugmann, R. A. Flynn, J. Wysocka, A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470, 279-283 (2011).
-
(2011)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Lglesias, A.1
Bajpai, R.2
Swigut, T.3
Brugmann, S.A.4
Flynn, R.A.5
Wysocka, J.6
-
53
-
-
69449102464
-
Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
-
Z. Wang, C. Zang, K. Cui, D. E. Schones, A. Barski, W. Peng, K. Zhao, Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138, 1019-1031 (2009).
-
(2009)
Cell
, vol.138
, pp. 1019-1031
-
-
Wang, Z.1
Zang, C.2
Cui, K.3
Schones, D.E.4
Barski, A.5
Peng, W.6
Zhao, K.7
-
54
-
-
0033525748
-
Generic signals and specific outcomes: Signaling through Ca2+, calcineurin, and NF-AT
-
G. R. Crabtree, Generic signals and specific outcomes: Signaling through Ca2+, calcineurin, and NF-AT. Cell 96, 611-614 (1999).
-
(1999)
Cell
, vol.96
, pp. 611-614
-
-
Crabtree, G.R.1
-
55
-
-
0036791792
-
Identification of a polymorphic, neuron-specific chromatin remodeling complex
-
I. Olave, W. Wang, Y. Xue, A. Kuo, G. R. Crabtree, Identification of a polymorphic, neuron-specific chromatin remodeling complex. Genes Dev. 16, 2509-2517 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 2509-2517
-
-
Olave, I.1
Wang, W.2
Xue, Y.3
Kuo, A.4
Crabtree, G.R.5
-
56
-
-
0346969980
-
Dendrite development regulated by CREST, a calcium-regulated transcriptional activator
-
H. Aizawa, S. C. Hu, K. Bobb, K. Balakrishnan, G. Ince, I. Gurevich, M. Cowan, A. Ghosh, Dendrite development regulated by CREST, a calcium-regulated transcriptional activator. Science 303, 197-202 (2004).
-
(2004)
Science
, vol.303
, pp. 197-202
-
-
Aizawa, H.1
Hu, S.C.2
Bobb, K.3
Balakrishnan, K.4
Ince, G.5
Gurevich, I.6
Cowan, M.7
Ghosh, A.8
-
57
-
-
84876903184
-
The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory
-
A. Vogel-Ciernia, D. P. Matheos, R. M. Barrett, E. A. Kramar, S. Azzawi, Y. Chen, C. N. Magnan, M. Zeller, A. Sylvain, J. Haettig, Y. Jia, A. Tran, R. Dang, R. J. Post, M. Chabrier, A. H. Babayan, J. I. Wu, G. R. Crabtree, P. Baldi, T. Z. Baram, G. Lynch, M. A. Wood, The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nat. Neurosci. 16, 552-561 (2013).
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 552-561
-
-
Vogel-Ciernia, A.1
Matheos, D.P.2
Barrett, R.M.3
Kramar, E.A.4
Azzawi, S.5
Chen, Y.6
Magnan, C.N.7
Zeller, M.8
Sylvain, A.9
Haettig, J.10
Jia, Y.11
Tran, A.12
Dang, R.13
Post, R.J.14
Chabrier, M.15
Babayan, A.H.16
Wu, J.I.17
Crabtree, G.R.18
Baldi, P.19
Baram, T.Z.20
Lynch, G.21
Wood, M.A.22
more..
-
58
-
-
84924666082
-
Developmentalstudgroup, Large-scale discovery of novel genetic causes of developmental disorders
-
Developmentalstudgroup, Large-scale discovery of novel genetic causes of developmental disorders. Nature 519, 223-228 (2014).
-
(2014)
Nature
, vol.519
, pp. 223-228
-
-
-
59
-
-
0028060515
-
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
-
J. L. Dunaief, B. E. Strober, S. Guha, P. A. Khavari, K. Alin, J. Luban, M. Begemann, G. R. Crabtree, S. P. Goff, The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 79, 119-130 (1994).
-
(1994)
Cell
, vol.79
, pp. 119-130
-
-
Dunaief, J.L.1
Strober, B.E.2
Guha, S.3
Khavari, P.A.4
Alin, K.5
Luban, J.6
Begemann, M.7
Crabtree, G.R.8
Goff, S.P.9
-
60
-
-
0030867899
-
RB and hbrm cooperate to repress the activation functions of E2F1
-
D. Trouche, C. Le Chalony, C. Muchardt, M. Yaniv, T. Kouzarides, RB and hbrm cooperate to repress the activation functions of E2F1. Proc. Natl. Acad. Sci. U.S.A. 94, 11268-11273 (1997).
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 11268-11273
-
-
Trouche, D.1
Le Chalony, C.2
Muchardt, C.3
Yaniv, M.4
Kouzarides, T.5
-
61
-
-
2642647094
-
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
-
I. Versteege, N. Sevenet, J. Lange, M. F. Rousseau-Merck, P. Ambros, R. Handgretinger, A. Aurias, O. Delattre, Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394, 203-206 (1998).
-
(1998)
Nature
, vol.394
, pp. 203-206
-
-
Versteege, I.1
Sevenet, N.2
Lange, J.3
Rousseau-Merck, M.F.4
Ambros, P.5
Handgretinger, R.6
Aurias, A.7
Delattre, O.8
-
62
-
-
85047698804
-
Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: Differential effects on RB-mediated growth arrest versus CD44 expression
-
D. N. Reisman, M. W. Strobeck, B. L. Betz, J. Sciariotta, W. Funkhouser Jr., C. Murchardt, M. Yaniv, L. S. Sherman, E. S. Knudsen, B. E. Weissman, Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: Differential effects on RB-mediated growth arrest versus CD44 expression. Oncogene 21, 1196-1207 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 1196-1207
-
-
Reisman, D.N.1
Strobeck, M.W.2
Betz, B.L.3
Sciariotta, J.4
Funkhouser, W.5
Murchardt, C.6
Yaniv, M.7
Sherman, L.S.8
Knudsen, E.S.9
Weissman, B.E.10
-
63
-
-
0034326257
-
BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines
-
A. K. Wong, F. Shanahan, Y. Chen, L. Lian, P. Ha, K. Hendricks, S. Ghaffari, D. Iliev, B. Penn, A. M. Woodland, R. Smith, G. Salada, A. Carillo, K. Laity, J. Gupte, B. Swedlund, S. V. Tavtigian, D. H. Teng, E. Lees, BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res. 60, 6171-6177 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 6171-6177
-
-
Wong, A.K.1
Shanahan, F.2
Chen, Y.3
Lian, L.4
Ha, P.5
Hendricks, K.6
Ghaffari, S.7
Iliev, D.8
Penn, B.9
Woodland, A.M.10
Smith, R.11
Salada, G.12
Carillo, A.13
Laity, K.14
Gupte, J.15
Swedlund, B.16
Tavtigian, S.V.17
Teng, D.H.18
Lees, E.19
-
64
-
-
77957946398
-
ARID1A mutations in endometriosis-associated ovarian carcinomas
-
K. C. Wiegand, S. P. Shah, O. M. Al-Agha, Y. Zhao, K. Tse, T. Zeng, J. Senz, M. K. McConechy, M. S. Anglesio, S. E. Kalloger, W. Yang, A. Heravi-Moussavi, R. Giuliany, C. Chow, J. Fee, A. Zayed, L. Prentice, N. Melnyk, G. Turashvili, A. D. Delaney, J. Madore, S. Yip, A. W. McPherson, G. Ha, L. Bell, S. Fereday, A. Tarn, L. Galletta, P. N. Tonin, D. Provencher, D. Miller, S.J. Jones, R. A. Moore, G. B. Morin, A. Oloumi, N. Boyd, S. A. Aparicio, I. M. Shih, A. M. Mes-Masson, D. D. Bowtell, M. Hirst, B. Gilks, M. A. Marra, D. G. Huntsman, ARID1A mutations in endometriosis-associated ovarian carcinomas. N. Engl. J. Med. 363, 1532-1543 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1532-1543
-
-
Wiegand, K.C.1
Shah, S.P.2
Al-Agha, O.M.3
Zhao, Y.4
Tse, K.5
Zeng, T.6
Senz, J.7
McConechy, M.K.8
Anglesio, M.S.9
Kalloger, S.E.10
Yang, W.11
Heravi-Moussavi, A.12
Giuliany, R.13
Chow, C.14
Fee, J.15
Zayed, A.16
Prentice, L.17
Melnyk, N.18
Turashvili, G.19
Delaney, A.D.20
Madore, J.21
Yip, S.22
McPherson, A.W.23
Ha, G.24
Bell, L.25
Fereday, S.26
Tarn, A.27
Galletta, L.28
Tonin, P.N.29
Provencher, D.30
Miller, D.31
Jones, S.J.32
Moore, R.A.33
Morin, G.B.34
Oloumi, A.35
Boyd, N.36
Aparicio, S.A.37
Shih, I.M.38
Mes-Masson, A.M.39
Bowtell, D.D.40
Hirst, M.41
Gilks, B.42
Marra, M.A.43
Huntsman, D.G.44
more..
-
65
-
-
84877254190
-
Integrated genomic characterization of endometrial carcinoma
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network, C. Kandoth, N. Schultz, A. D. Cherniack, R. Akbani, Y. Liu, H. Shen, A. G. Robertson, I. Pashtan, R. Shen, C. C Benz, C. Yau, P. W. Laird, L. Ding, W. Zhang, G. B. Mills, R. Kucherlapati, E. R. Mardis, D. A. Levine, Integrated genomic characterization of endometrial carcinoma. Nature 497, 67-73 (2013).
-
(2013)
Nature
, vol.497
, pp. 67-73
-
-
Kandoth, C.1
Schultz, N.2
Cherniack, A.D.3
Akbani, R.4
Liu, Y.5
Shen, H.6
Robertson, A.G.7
Pashtan, I.8
Shen, R.9
Benz, C.C.10
Yau, C.11
Laird, P.W.12
Ding, L.13
Zhang, W.14
Mills, G.B.15
Kucherlapati, R.16
Mardis, E.R.17
Levine, D.A.18
-
66
-
-
84899644463
-
Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type
-
L. Witkowski, J. Carrot-Zhang, S. Albrecht, S. Fahiminiya, N. Hamel, E. Tomiak, D. Grynspan, E. Saloustros, J. Nadaf, B. Rivera, C. Gilpin, E. Castellsague, R. Silva-Smith, F. Plourde, M. Wu, A. Saskin, M. Arseneault, R. G. Karabakhtsian, E. A. Reilly, F. R. Ueland, A. Margiolaki, K. Pavlakis, S. M. Castellino, J. Lamovec, H. J. Mackay, L. M. Roth, T. M. Ulbright, T. A. Bender, V. Georgoulias, M. Longy, A. Berchuck, M. Tischkowitz, I. Nagel, R. Siebert, C. J. Stewart, J. Arseneau, W. G. McCluggage, B. A. Clarke, Y. Riazalhosseini, M. Hasselblatt, J. Majewski, W. D. Foulkes, Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type. Nat. Genet. 46, 438-443 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 438-443
-
-
Witkowski, L.1
Carrot-Zhang, J.2
Albrecht, S.3
Fahiminiya, S.4
Hamel, N.5
Tomiak, E.6
Grynspan, D.7
Saloustros, E.8
Nadaf, J.9
Rivera, B.10
Gilpin, C.11
Castellsague, E.12
Silva-Smith, R.13
Plourde, F.14
Wu, M.15
Saskin, A.16
Arseneault, M.17
Karabakhtsian, R.G.18
Reilly, E.A.19
Ueland, F.R.20
Margiolaki, A.21
Pavlakis, K.22
Castellino, S.M.23
Lamovec, J.24
Mackay, H.J.25
Roth, L.M.26
Ulbright, T.M.27
Bender, T.A.28
Georgoulias, V.29
Longy, M.30
Berchuck, A.31
Tischkowitz, M.32
Nagel, I.33
Siebert, R.34
Stewart, C.J.35
Arseneau, J.36
McCluggage, W.G.37
Clarke, B.A.38
Riazalhosseini, Y.39
Hasselblatt, M.40
Majewski, J.41
Foulkes, W.D.42
more..
-
67
-
-
84899635792
-
Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4
-
P. Ramos, A. N. Karnezis, D. W. Craig, A. Sekulic, M. L. Russell, W. P. Hendricks, J. J. Corneveaux, M. T. Barrett, K. Shumansky, Y. Yang, S. P. Shah, L. M. Prentice, M. A. Marra, J. Kiefer, V. L. Zismann, T. A. McEachron, B. Salhia, J. Prat, E. D'Angelo, B. A. Clarke, J. G. Pressey, J. H. Farley, S. P. Anthony, R. B. Roden, H. E. Cunliffe, D. G. Huntsman, J. M. Trent, Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4. Nat. Genet. 46, 427-429 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 427-429
-
-
Ramos, P.1
Karnezis, A.N.2
Craig, D.W.3
Sekulic, A.4
Russell, M.L.5
Hendricks, W.P.6
Corneveaux, J.J.7
Barrett, M.T.8
Shumansky, K.9
Yang, Y.10
Shah, S.P.11
Prentice, L.M.12
Marra, M.A.13
Kiefer, J.14
Zismann, V.L.15
McEachron, T.A.16
Salhia, B.17
Prat, J.18
D'Angelo, E.19
Clarke, B.A.20
Pressey, J.G.21
Farley, J.H.22
Anthony, S.P.23
Roden, R.B.24
Cunliffe, H.E.25
Huntsman, D.G.26
Trent, J.M.27
more..
-
68
-
-
0034610395
-
Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice
-
C. W. Roberts, S. A. Galusha, M. E. McMenamin, C. D. Fletcher, S. H. Orkin, Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice. Proc. Natl. Acad. Sci. U.S.A. 97, 13796-13800 (2000).
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13796-13800
-
-
Roberts, C.W.1
Galusha, S.A.2
McMenamin, M.E.3
Fletcher, C.D.4
Orkin, S.H.5
-
69
-
-
77957955244
-
Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation
-
B. G. Wilson, X. Wang, X. Shen, E. S. McKenna, M. E. Lemieux, Y. J. Cho, E. C. Koellhoffer, S. L. Pomeroy, S. H. Orkin, C. W. Roberts, Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation. Cancer Ceil 18, 316-328 (2010) .
-
(2010)
Cancer Ceil
, vol.18
, pp. 316-328
-
-
Wilson, B.G.1
Wang, X.2
Shen, X.3
McKenna, E.S.4
Lemieux, M.E.5
Cho, Y.J.6
Koellhoffer, E.C.7
Pomeroy, S.L.8
Orkin, S.H.9
Roberts, C.W.10
-
70
-
-
80053404572
-
TCR-dependent transformation of mature memory phenotypeT cells in mice
-
X. Wang, M. B. Werneck, B. G. Wilson, H. J. Kim, M. J. Kluk, C. S. Thorn, J. W. Wischhusen, J. A. Evans, J. L. Jesneck, P. Nguyen, C. G. Sansam, H. Cantor, C. W. Roberts, TCR-dependent transformation of mature memory phenotypeT cells in mice. J. Clin, invest. 121, 3834-3845 (2011) .
-
(2011)
J. Clin, Invest.
, vol.121
, pp. 3834-3845
-
-
Wang, X.1
Werneck, M.B.2
Wilson, B.G.3
Kim, H.J.4
Kluk, M.J.5
Thorn, C.S.6
Wischhusen, J.W.7
Evans, J.A.8
Jesneck, J.L.9
Nguyen, P.10
Sansam, C.G.11
Cantor, H.12
Roberts, C.W.13
-
71
-
-
84892833777
-
Discovery and saturation analysis of cancer genes across 21 tumour types
-
M. S. Lawrence, P. Stojanov, C. H. Mermel, J. T. Robinson, L. A. Garraway, T. R. Golub, M. Meyerson, S. B. Gabriel, E. S. Lander, G. Getz, Discovery and saturation analysis of cancer genes across 21 tumour types. Nature 505, 495-501 (2014).
-
(2014)
Nature
, vol.505
, pp. 495-501
-
-
Lawrence, M.S.1
Stojanov, P.2
Mermel, C.H.3
Robinson, J.T.4
Garraway, L.A.5
Golub, T.R.6
Meyerson, M.7
Gabriel, S.B.8
Lander, E.S.9
Getz, G.10
-
72
-
-
84870950067
-
Cancer Genome Atlas Network, Comprehensive molecular characterization of human colon and rectal cancer
-
Cancer Genome Atlas Network, Comprehensive molecular characterization of human colon and rectal cancer. Nature 487, 330-337 (2012).
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
73
-
-
84869091997
-
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
-
Australian Pancreatic Cancer Genome Initiative
-
A. V. Biankin, N. Waddell, K. S. Kassahn, M. C. Gingras, L. B. Muthuswamy, A. L. Johns, D. K. Miller, P. J. Wilson, A. M. Patch, J. Wu, D. K. Chang, M. J. Cowley, B. B. Gardiner, S. Song, I. Harliwong, S. Idrisoglu, C. Nourse, E. Nourbakhsh, S. Manning, S. Wani, M. Gongora, M. Pajic, C.J. Scarlett, A. J. Gill, A. V. Pinho, I. Rooman, M. Anderson, O. Holmes, C. Leonard, D. Taylor, S. Wood, Q. Xu, K. Nones, J. L. Fink, A. Christ, T. Bruxner, N. Cloonan, G. Kolle, F. Newell, M. Pinese, R. S. Mead, J. L. Humphris, W. Kaplan, M. D. Jones, E. K. Colvin, A. M. Nagrial, E. S. Humphrey, A. Chou, V. T. Chin, L. A. Chantrill, A. Mawson, J. S. Samra, J. G. Kench, J. A. Lovell, R. J. Daly, N. D. Merrett, C. Toon, K. Epari, N. Q. Nguyen, A. Barbour, N. Zeps, Australian Pancreatic Cancer Genome Initiative, N. Kakkar, F. Zhao, Y. Q. Wu, M. Wang, D. M. Muzny, W. E. Fisher, F. C. Brunicardi, S. E. Hodges, J. G. Reid, J. Drummond, K. Chang, Y. Han, L. R. Lewis, H. Dinh, C. J. Buhay, T. Beck, L. Timms, M. Sam, K. Begley, A. Brown, D. Pai, A. Panchal, N. Buchner, R. De Borja, R. E. Denroche, C. K. Yung, S. Serra, N. Onetto, D. Mukhopadhyay, M. S. Tsao, P. A. Shaw, G. M. Petersen, S. Gallinger, R. H. Hruban, A. Maitra, C. A. lacobuzio-Donahue, R. D. Schulick, C. L. Wolfgang, R. A. Morgan, R. T. Lawlor, P. Capelli, V. Corbo, M. Scardoni, G. Tortora, M. A. Tempero, K. M. Mann, N. A. Jenkins, P. A. Perez-Mancera, D. J. Adams, D. A. Largaespada, L. F. Wessels, A. G. Rust, L. D. Stein, D. A. Tuveson, N. G. Copeland, E. A. Musgrove, A. Scarpa, J. R. Eshleman, T. J. Hudson, R. L. Sutherland, D. A. Wheeler, J. V. Pearson, J. D. McPherson, R. A. Gibbs, S. M. Grimmond, Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 491, 399-405 (2012).
-
(2012)
Nature
, vol.491
, pp. 399-405
-
-
Biankin, A.V.1
Waddell, N.2
Kassahn, K.S.3
Gingras, M.C.4
Muthuswamy, L.B.5
Johns, A.L.6
Miller, D.K.7
Wilson, P.J.8
Patch, A.M.9
Wu, J.10
Chang, D.K.11
Cowley, M.J.12
Gardiner, B.B.13
Song, S.14
Harliwong, I.15
Idrisoglu, S.16
Nourse, C.17
Nourbakhsh, E.18
Manning, S.19
Wani, S.20
Gongora, M.21
Pajic, M.22
Scarlett, C.J.23
Gill, A.J.24
Pinho, A.V.25
Rooman, I.26
Anderson, M.27
Holmes, O.28
Leonard, C.29
Taylor, D.30
Wood, S.31
Xu, Q.32
Nones, K.33
Fink, J.L.34
Christ, A.35
Bruxner, T.36
Cloonan, N.37
Kolle, G.38
Newell, F.39
Pinese, M.40
Mead, R.S.41
Humphris, J.L.42
Kaplan, W.43
Jones, M.D.44
Colvin, E.K.45
Nagrial, A.M.46
Humphrey, E.S.47
Chou, A.48
Chin, V.T.49
Chantrill, L.A.50
Mawson, A.51
Samra, J.S.52
Kench, J.G.53
Lovell, J.A.54
Daly, R.J.55
Merrett, N.D.56
Toon, C.57
Epari, K.58
Nguyen, N.Q.59
Barbour, A.60
Zeps, N.61
Kakkar, N.62
Zhao, F.63
Wu, Y.Q.64
Wang, M.65
Muzny, D.M.66
Fisher, W.E.67
Brunicardi, F.C.68
Hodges, S.E.69
Reid, J.G.70
Drummond, J.71
Chang, K.72
Han, Y.73
Lewis, L.R.74
Dinh, H.75
Buhay, C.J.76
Beck, T.77
Timms, L.78
Sam, M.79
Begley, K.80
Brown, A.81
Pai, D.82
Panchal, A.83
Buchner, N.84
De Borja, R.85
Denroche, R.E.86
Yung, C.K.87
Serra, S.88
Onetto, N.89
Mukhopadhyay, D.90
Tsao, M.S.91
Shaw, P.A.92
Petersen, G.M.93
Gallinger, S.94
Hruban, R.H.95
Maitra, A.96
Lacobuzio-Donahue, C.A.97
Schulick, R.D.98
Wolfgang, C.L.99
more..
-
74
-
-
80052266351
-
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
-
Y. Gui, G. Guo, Y. Huang, X. Hu, A. Tang, S. Gao, R. Wu, C. Chen, X. Li, L. Zhou, M. He, Z. Li, X. Sun, W. Jia, J. Chen, S. Yang, F. Zhou, X. Zhao, S. Wan, R. Ye, C. Liang, Z. Liu, P. Huang, C. Liu, H. Jiang, Y. Wang, H. Zheng, L. Sun, X. Liu, Z. Jiang, D. Feng, J. Chen, S. Wu, J. Zou, Z. Zhang, R. Yang, J. Zhao, C. Xu, W. Yin, Z. Guan, J. Ye, H. Zhang, J. Li, K. Kristiansen, M. L. Nickerson, D. Theodorescu, Y. Li, X. Zhang, S. Li, J. Wang, H. Yang, J. Wang, Z. Cai, Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat. Genet 43, 875-878 (2011).
-
(2011)
Nat. Genet
, vol.43
, pp. 875-878
-
-
Gui, Y.1
Guo, G.2
Huang, Y.3
Hu, X.4
Tang, A.5
Gao, S.6
Wu, R.7
Chen, C.8
Li, X.9
Zhou, L.10
He, M.11
Li, Z.12
Sun, X.13
Jia, W.14
Chen, J.15
Yang, S.16
Zhou, F.17
Zhao, X.18
Wan, S.19
Ye, R.20
Liang, C.21
Liu, Z.22
Huang, P.23
Liu, C.24
Jiang, H.25
Wang, Y.26
Zheng, H.27
Sun, L.28
Liu, X.29
Jiang, Z.30
Feng, D.31
Chen, J.32
Wu, S.33
Zou, J.34
Zhang, Z.35
Yang, R.36
Zhao, J.37
Xu, C.38
Yin, W.39
Guan, Z.40
Ye, J.41
Zhang, H.42
Li, J.43
Kristiansen, K.44
Nickerson, M.L.45
Theodorescu, D.46
Li, Y.47
Zhang, X.48
Li, S.49
Wang, J.50
Yang, H.51
Wang, J.52
Cai, Z.53
more..
-
75
-
-
82255183148
-
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
-
K. Wang, J. Kan, S. T. Yuen, S. T. Shi, K. M. Chu, S. Law, T. L. Chan, Z. Kan, A. S. Chan, W. Y. Tsui, S. P. Lee, S. L. Ho, A. K. Chan, G. H. Cheng, P. C. Roberts, P. A. Rejto, N. W. Gibson, D. J. Pocalyko, M. Mao, J. Xu, S. Y. Leung, Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nat. Genet. 43, 1219-1223 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 1219-1223
-
-
Wang, K.1
Kan, J.2
Yuen, S.T.3
Shi, S.T.4
Chu, K.M.5
Law, S.6
Chan, T.L.7
Kan, Z.8
Chan, A.S.9
Tsui, W.Y.10
Lee, S.P.11
Ho, S.L.12
Chan, A.K.13
Cheng, G.H.14
Roberts, P.C.15
Rejto, P.A.16
Gibson, N.W.17
Pocalyko, D.J.18
Mao, M.19
Xu, J.20
Leung, S.Y.21
more..
-
76
-
-
84901680089
-
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer
-
K. Wang, S. T. Yuen, J. Xu, S. P. Lee, H. H. Yan, S. T. Shi, H. C. Siu, S. Deng, K. M. Chu, S. Law, K. H. Chan, A. S. Chan, W. Y. Tsui, S. L. Ho, A. K. Chan, J. L. Man, V. Foglizzo, M. K. Ng, A. S. Chan, Y. P. Ching, G. H. Cheng, T. Xie, J. Fernandez, V. S. Li, H. Clevers, P. A. Rejto, M. Mao, S. Y. Leung, Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. Nat. Genet. 46, 573-582 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 573-582
-
-
Wang, K.1
Yuen, S.T.2
Xu, J.3
Lee, S.P.4
Yan, H.H.5
Shi, S.T.6
Siu, H.C.7
Deng, S.8
Chu, K.M.9
Law, S.10
Chan, K.H.11
Chan, A.S.12
Tsui, W.Y.13
Ho, S.L.14
Chan, A.K.15
Man, J.L.16
Foglizzo, V.17
Ng, M.K.18
Chan, A.S.19
Ching, Y.P.20
Cheng, G.H.21
Xie, T.22
Fernandez, J.23
Li, V.S.24
Clevers, H.25
Rejto, P.A.26
Mao, M.27
Leung, S.Y.28
more..
-
77
-
-
84888385562
-
Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers
-
W. Chan-On, M. L Nairismagi, C K. Ong, W. K. Lim, S. Dima, C Pairojkul, K. H. Lim, J. R. McPherson, I. Cutcutache, H. L. Heng, L. Ooi, A. Chung, P. Chow, P. C. Cheow, S. Y. Lee, S. P. Choo, I. B. Tan, D. Duda, A. Nastase, S. S. Myint, B. H. Wong, A. Gan, V. Rajasegaran, C. C. Ng, S. Nagarajan, A. Jusakul, S. Zhang, P. Vohra, W. Yu, D. Huang, P. Sithithaworn, P. Yongvanit, S. Wongkham, N. Khuntikeo, V. Bhudhisawasdi, I. Popescu, S. G. Rozen, P. Tan, B. T. Teh, Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers. Nat. Genet. 45, 1474-1478 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 1474-1478
-
-
Chan-On, W.1
Nairismagi, M.L.2
Ong, C.K.3
Lim, W.K.4
Dima, S.5
Pairojkul, C.6
Lim, K.H.7
McPherson, J.R.8
Cutcutache, I.9
Heng, H.L.10
Ooi, L.11
Chung, A.12
Chow, P.13
Cheow, P.C.14
Lee, S.Y.15
Choo, S.P.16
Tan, I.B.17
Duda, D.18
Nastase, A.19
Myint, S.S.20
Wong, B.H.21
Gan, A.22
Rajasegaran, V.23
Ng, C.C.24
Nagarajan, S.25
Jusakul, A.26
Zhang, S.27
Vohra, P.28
Yu, W.29
Huang, D.30
Sithithaworn, P.31
Yongvanit, P.32
Wongkham, S.33
Khuntikeo, N.34
Bhudhisawasdi, V.35
Popescu, I.36
Rozen, S.G.37
Tan, P.38
Teh, B.T.39
more..
-
78
-
-
84871982155
-
Integrated genomic analyses identify ARID 1A and ARID1B alterations in the childhood cancer neuroblastoma
-
S. M. Sausen, R. J. Leary, S. Jones, J. Wu, C. P. Reynolds, X. Liu, A. Blackford, G. Parmigiani, L. A. Diaz Jr., N. Papadopoulos, B. Vogelstein, K. W. Kinzler, V. E. Velculescu, M. D. Hogarty, Integrated genomic analyses identify ARID 1A and ARID1B alterations in the childhood cancer neuroblastoma. Nat. Genet. 45, 12-17 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 12-17
-
-
Sausen, S.M.1
Leary, R.J.2
Jones, S.3
Wu, J.4
Reynolds, C.P.5
Liu, X.6
Blackford, A.7
Parmigiani, G.8
Diaz, L.A.9
Papadopoulos, N.10
Vogelstein, B.11
Kinzler, K.W.12
Velculescu, V.E.13
Hogarty, M.D.14
-
79
-
-
84871867133
-
ARID1 A-DNA interactions are required for promoter occupancy by SWI/SNF
-
R. L. Chandler, J. Brennan, J. C. Schisler, D. Serber, C. Patterson, T. Magnuson, ARID1 a-DNA interactions are required for promoter occupancy by SWI/SNF. Mol. Cell. Biol. 33,265-280 (2013).
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 265-280
-
-
Chandler, R.L.1
Brennan, J.2
Schisler, J.C.3
Serber, D.4
Patterson, C.5
Magnuson, T.6
-
80
-
-
77949384048
-
Mammalian SWI/SNF-A subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B
-
X. S. Li, P. Trojer, T. Matsumura, J. E. Treisman, N. Tanese, Mammalian SWI/SNF-A subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B. Mol. Cell. Biol. 30,1673-1688 (2010).
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1673-1688
-
-
Li, X.S.1
Trojer, P.2
Matsumura, T.3
Treisman, J.E.4
Tanese, N.5
-
81
-
-
77956607725
-
A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations
-
J. Krosl, A. Mamo, J. Chagraoui, B. T. Wilhelm, S. Girard, I. Louis, J. Lessard, C. Perreault, G. Sauvageau, A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations. Blood 116, 1678-1684 (2010).
-
(2010)
Blood
, vol.116
, pp. 1678-1684
-
-
Krosl, J.1
Mamo, A.2
Chagraoui, J.3
Wilhelm, B.T.4
Girard, S.5
Louis, I.6
Lessard, J.7
Perreault, C.8
Sauvageau, G.9
-
82
-
-
84896898658
-
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1 -deficient cancers
-
G. R. Hoffman, R. Rahal, F. Buxton, K. Xiang, G. McAllister, E. Frias, L. Bagdasarian, J. Huber, A. Lindeman, D. Chen, R. Romero, N. Ramadan, T. Phadke, K. Haas, M. Jaskelioff, B. G. Wilson, M. J. Meyer, V. Saenz-Vash, H. Zhai, V. E. Myer, J. A. Porter, N. Keen, M. E. McLaughlin, C. Mickanin, C. W. Roberts, F. Stegmeier, Z. Jagani, Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1 -deficient cancers. Proc. Natl. Acad. Sci. U.S.A. Ill, 3128-3133 (2014).
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 3128-3133
-
-
Hoffman, G.R.1
Rahal, R.2
Buxton, F.3
Xiang, K.4
McAllister, G.5
Frias, E.6
Bagdasarian, L.7
Huber, J.8
Lindeman, A.9
Chen, D.10
Romero, R.11
Ramadan, N.12
Phadke, T.13
Haas, K.14
Jaskelioff, M.15
Wilson, B.G.16
Meyer, M.J.17
Saenz-Vash, V.18
Zhai, H.19
Myer, V.E.20
Porter, J.A.21
Keen, N.22
McLaughlin, M.E.23
Mickanin, C.24
Roberts, C.W.25
Stegmeier, F.26
Jagani, Z.27
more..
-
83
-
-
84874657913
-
Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas
-
M. J. Smith, J. O'Sullivan, S. S. Bhaskar, K. D. Hadfield, G. Poke, J. Caird, S. Sharif, D. Eccles, D. Fitzpatrick, D. Rawluk, D. du Plessis, W. G. Newman, D. G. Evans, Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas. Nat. Genet. 45, 295-298 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 295-298
-
-
Smith, M.J.1
O'Sullivan, J.2
Bhaskar, S.S.3
Hadfield, K.D.4
Poke, G.5
Caird, J.6
Sharif, S.7
Eccles, D.8
Fitzpatrick, D.9
Rawluk, D.10
Du Plessis, D.11
Newman, W.G.12
Evans, D.G.13
-
84
-
-
0041429637
-
Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development
-
T. H. Chi, M. Wan, P. P. Lee, K. Akashi, D. Metzger, P. Chambon, C. B. Wilson, G. R. Crabtree, Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. Immunity 19, 169-182 (2003).
-
(2003)
Immunity
, vol.19
, pp. 169-182
-
-
Chi, T.H.1
Wan, M.2
Lee, P.P.3
Akashi, K.4
Metzger, D.5
Chambon, P.6
Wilson, C.B.7
Crabtree, G.R.8
-
85
-
-
84908615607
-
Coffin-Siris Syndrome International Collaborators, Genotype-phenotype correlation of Coffin-Siris syndrome caused by mutations in SMARCB1, SMARCA4, SMARCE1, and (ARID)A
-
T. Kosho, N. Okamoto; Coffin-Siris Syndrome International Collaborators, Genotype-phenotype correlation of Coffin-Siris syndrome caused by mutations in SMARCB1, SMARCA4, SMARCE1, and ARID)A. Am. J. Med. Genet. C Semin. Med. Genet. 166C, 262-275 (2014).
-
(2014)
Am. J. Med. Genet. C Semin. Med. Genet.
, vol.166 C
, pp. 262-275
-
-
Kosho, T.1
Okamoto, N.2
-
86
-
-
84872667632
-
Frameshift mutations of a chromatin-remodeling gene SMARCC2 in gastric and colorectal cancers with microsatellite instability
-
S. S. Kim, M. S. Kim, N. J. Yoo, S. H. Lee, Frameshift mutations of a chromatin-remodeling gene SMARCC2 in gastric and colorectal cancers with microsatellite instability. APMIS 121, 168-9 (2013).
-
(2013)
APMIS
, vol.121
, pp. 168-169
-
-
Kim, S.S.1
Kim, M.S.2
Yoo, N.J.3
Lee, S.H.4
-
87
-
-
84861576201
-
The landscape of cancer genes and mutational processes in breast cancer
-
Oslo Breast Cancer Consortium (OSBREAC)
-
P. J. Stephens, P. S. Tarpey, H. Davies, P. Van Loo, C. Greenman, D. C. Wedge, S. Nik-Zainal, S. Martin, I. Varela, G. R. Bignell, L. R. Yates, E. Papaemmanuil, D. Beare, A. Butler, A. Cheverton, J. Gamble, J. Hinton, M. Jia, A. Jayakumar, D. Jones, C. Latimer, K. W. Lau, S. McLaren, D.J. McBride, A. Menzies, L. Mudie, K. Raine, R. Rad, M. S. Chapman, J. Teague, D. Easton, A. Langerod, Oslo Breast Cancer Consortium (OSBREAC), M. T. Lee, C. Y. Shen, B. T. Tee, B. W. Huimin, A. Broeks, A. C. Vargas, G. Turashvili, J. Martens, A. Fatima, P. Miron, S. F. Chin, G. Thomas, S. Boyault, O. Mariani, S. R. Lakhani, M. van de Vijver, L. van't Veer, J. Foekens, C Desmedt, C. Sotiriou, A. Tutt, C. Caldas, J. S. Reis-Filho, S. A. Aparicio, A. V. Salomon, A. L. Borresen-Dale, A. L. Richardson, P. J. Campbell, P. A. Futreal, M. R. Stratton, The landscape of cancer genes and mutational processes in breast cancer. Nature 486, 400-404 (2012).
-
(2012)
Nature
, vol.486
, pp. 400-404
-
-
Stephens, P.J.1
Tarpey, P.S.2
Davies, H.3
Van Loo, P.4
Greenman, C.5
Wedge, D.C.6
Nik-Zainal, S.7
Martin, S.8
Varela, I.9
Bignell, G.R.10
Yates, L.R.11
Papaemmanuil, E.12
Beare, D.13
Butler, A.14
Cheverton, A.15
Gamble, J.16
Hinton, J.17
Jia, M.18
Jayakumar, A.19
Jones, D.20
Latimer, C.21
Lau, K.W.22
McLaren, S.23
McBride, D.J.24
Menzies, A.25
Mudie, L.26
Raine, K.27
Rad, R.28
Chapman, M.S.29
Teague, J.30
Easton, D.31
Langerod, A.32
Lee, M.T.33
Shen, C.Y.34
Tee, B.T.35
Huimin, B.W.36
Broeks, A.37
Vargas, A.C.38
Turashvili, G.39
Martens, J.40
Fatima, A.41
Miron, P.42
Chin, S.F.43
Thomas, G.44
Boyault, S.45
Mariani, O.46
Lakhani, S.R.47
Van De Vijver, M.48
Van'T Veer, L.49
Foekens, J.50
Desmedt, C.51
Sotiriou, C.52
Tutt, A.53
Caldas, C.54
Reis-Filho, J.S.55
Aparicio, S.A.56
Salomon, A.V.57
Borresen-Dale, A.L.58
Richardson, A.L.59
Campbell, P.J.60
Futreal, P.A.61
Stratton, M.R.62
more..
-
88
-
-
0029066330
-
Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma
-
A. J. Crew, J. Clark, C Fisher, S. Gill, R. Grimer, A. Chand, J. Shipley, B. A. Gusterson, C. S. Cooper, Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma. Embo J 14, 2333-2340 (1995).
-
(1995)
Embo J
, vol.14
, pp. 2333-2340
-
-
Crew, A.J.1
Clark, J.2
Fisher, C.3
Gill, S.4
Grimer, R.5
Chand, A.6
Shipley, J.7
Gusterson, B.A.8
Cooper, C.S.9
-
89
-
-
77954823179
-
Synovial sarcoma is a stem cell malignancy
-
N. Naka, S. Takenaka, N. Araki, T. Miwa, N. Hashimoto, K. Yoshioka, S. Joyama, K. Hamada, Y. Tsukamoto, Y. Tomita, T. Ueda, H. Yoshikawa, K. Itoh, Synovial sarcoma is a stem cell malignancy. Stem Cells 28, 1119-1131 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 1119-1131
-
-
Naka, N.1
Takenaka, S.2
Araki, N.3
Miwa, T.4
Hashimoto, N.5
Yoshioka, K.6
Joyama, S.7
Hamada, K.8
Tsukamoto, Y.9
Tomita, Y.10
Ueda, T.11
Yoshikawa, H.12
Itoh, K.13
-
90
-
-
0027933151
-
Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma
-
J. Clark, P. J. Rocques, A. J. Crew, S. Gill, J. Shipley, A. M. Chan, B. A. Gusterson, C. S. Cooper, Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. Nat. Genet. 7, 502-508 (1994).
-
(1994)
Nat. Genet.
, vol.7
, pp. 502-508
-
-
Clark, J.1
Rocques, P.J.2
Crew, A.J.3
Gill, S.4
Shipley, J.5
Chan, A.M.6
Gusterson, B.A.7
Cooper, C.S.8
-
91
-
-
0035924326
-
Selectivity of chromatin-remodelling cofactors for ligand-activated transcription
-
B. Lemon, C. Inouye, D. S. King, R. Tjian, Selectivity of chromatin-remodelling cofactors for ligand-activated transcription. Nature 414, 924-927 (2001).
-
(2001)
Nature
, vol.414
, pp. 924-927
-
-
Lemon, B.1
Inouye, C.2
King, D.S.3
Tjian, R.4
-
92
-
-
79251635938
-
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
-
I. Varela, P. Tarpey, K. Raine, D. Huang, C. K. Ong, P. Stephens, H. Davies, D. Jones, M. L. Lin, J. Teague, G. Bignell, A. Butler, J. Cho, G. L. Dalgliesh, D. Galappaththige, C. Greenman, C. Hardy, M. Jia, C. Latimer, K. W. Lau, J. Marshall, S. McLaren, A. Menzies, L. Mudie, L. Stebbings, D. A. Largaespada, L. F. Wessels, S. Richard, R. J. Kahnoski, J. Anema, D. A. Tuveson, P. A. Perez-Mancera, V. Mustonen, A. Fischer, D. J. Adams, A. Rust, W. Chan-on, C. Subimerb, K. Dykema, K. Furge, P. J. Campbell, B. T. Teh, M. R. Stratton, P. A. Futreal, Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469, 539-542 (2011).
-
(2011)
Nature
, vol.469
, pp. 539-542
-
-
Varela, I.1
Tarpey, P.2
Raine, K.3
Huang, D.4
Ong, C.K.5
Stephens, P.6
Davies, H.7
Jones, D.8
Lin, M.L.9
Teague, J.10
Bignell, G.11
Butler, A.12
Cho, J.13
Dalgliesh, G.L.14
Galappaththige, D.15
Greenman, C.16
Hardy, C.17
Jia, M.18
Latimer, C.19
Lau, K.W.20
Marshall, J.21
McLaren, S.22
Menzies, A.23
Mudie, L.24
Stebbings, L.25
Largaespada, D.A.26
Wessels, L.F.27
Richard, S.28
Kahnoski, R.J.29
Anema, J.30
Tuveson, D.A.31
Perez-Mancera, P.A.32
Mustonen, V.33
Fischer, A.34
Adams, D.J.35
Rust, A.36
Chan-On, W.37
Subimerb, C.38
Dykema, K.39
Furge, K.40
Campbell, P.J.41
Teh, B.T.42
Stratton, M.R.43
Futreal, P.A.44
more..
-
93
-
-
84895876130
-
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
-
M. Gerlinger, S. Horswell, J. Larkin, A. J. Rowan, M. P. Salm, I. Varela, R. Fisher, N. McGranahan, N. Matthews, C. R. Santos, P. Martinez, B. Phillimore, S. Begum, A. Rabinowitz, B. Spencer-Dene, S. Gulati, P. A. Bates, G. Stamp, L. Pickering, M. Gore, D. L. Nicol, S. Hazell, P. A. Futreal, A. Stewart, C. Swanton, Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing. Nat. Genet. 46, 225-233 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 225-233
-
-
Gerlinger, M.1
Horswell, S.2
Larkin, J.3
Rowan, A.J.4
Salm, M.P.5
Varela, I.6
Fisher, R.7
McGranahan, N.8
Matthews, N.9
Santos, C.R.10
Martinez, P.11
Phillimore, B.12
Begum, S.13
Rabinowitz, A.14
Spencer-Dene, B.15
Gulati, S.16
Bates, P.A.17
Stamp, G.18
Pickering, L.19
Gore, M.20
Nicol, D.L.21
Hazell, S.22
Futreal, P.A.23
Stewart, A.24
Swanton, C.25
more..
-
94
-
-
80052271807
-
Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma
-
M. Li, H. Zhao, X. Zhang, L. D. Wood, R. A. Anders, M. A. Choti, T. M. Pawlik, H. D. Daniel, R. Kannangai, G. J. Offerhaus, V. E. Velculescu, L. Wang, S. Zhou, B. Vogelstein, R. H. Hruban, N. Papadopoulos, J. Cai, M. S. Torbenson, K. W. Kinzler, Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma. Nat. Genet. 43, 828-829 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 828-829
-
-
Li, M.1
Zhao, H.2
Zhang, X.3
Wood, L.D.4
Anders, R.A.5
Choti, M.A.6
Pawlik, T.M.7
Daniel, H.D.8
Kannangai, R.9
Offerhaus, G.J.10
Velculescu, V.E.11
Wang, L.12
Zhou, S.13
Vogelstein, B.14
Hruban, R.H.15
Papadopoulos, N.16
Cai, J.17
Torbenson, M.S.18
Kinzler, K.W.19
-
95
-
-
84943272498
-
Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity
-
A. Fujimoto, M. Furuta, Y. Shiraishi, K. Gotoh, Y. Kawakami, K. Arihiro, T. Nakamura, M. Ueno, S. Ariizumi, H. H. Nguyen, D. Shigemizu, T. Abe, K. A. Boroevich, K. Nakano, A. Sasaki, R. Kitada, K. Maejima, Y. Yamamoto, H. Tanaka, T. Shibuya, T. Shibata, H. Ojima, K. Shimada, S. Hayami, Y. Shigekawa, H. Aikata, H. Ohdan, S. Marubashi, T. Yamada, M. Kubo, S. Hirano, O. Ishikawa, M. Yamamoto, H. Yamaue, K. Chayama, S. Miyano, T. Tsunoda, H. Nakagawa, Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. Nat. Commun. 6, 6120 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 6120
-
-
Fujimoto, A.1
Furuta, M.2
Shiraishi, Y.3
Gotoh, K.4
Kawakami, Y.5
Arihiro, K.6
Nakamura, T.7
Ueno, M.8
Ariizumi, S.9
Nguyen, H.H.10
Shigemizu, D.11
Abe, T.12
Boroevich, K.A.13
Nakano, K.14
Sasaki, A.15
Kitada, R.16
Maejima, K.17
Yamamoto, Y.18
Tanaka, H.19
Shibuya, T.20
Shibata, T.21
Ojima, H.22
Shimada, K.23
Hayami, S.24
Shigekawa, Y.25
Aikata, H.26
Ohdan, H.27
Marubashi, S.28
Yamada, T.29
Kubo, M.30
Hirano, S.31
Ishikawa, O.32
Yamamoto, M.33
Yamaue, H.34
Chayama, K.35
Miyano, S.36
Tsunoda, T.37
Nakagawa, H.38
more..
-
96
-
-
0037022632
-
Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex
-
O. J. Rando, K. Zhao, P. Janmey, G. R. Crabtree, Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex. Proc. Natl. Acad. Sci. U.S.A. 99, 2824-2829 (2002).
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 2824-2829
-
-
Rando, O.J.1
Zhao, K.2
Janmey, P.3
Crabtree, G.R.4
-
97
-
-
84878400830
-
BAF complexes facilitate decatenation of DNA by topoisomerase
-
E. C. Dykhuizen, D. C. Hargreaves, E. L. Miller, K. Cui, A. Korshunov, M. Kool, S. Pfister, Y. J. Cho, K. Zhao, G. R. Crabtree, BAF complexes facilitate decatenation of DNA by topoisomerase Met. Nature 497, 624-627 (2013).
-
(2013)
Met. Nature
, vol.497
, pp. 624-627
-
-
Dykhuizen, E.C.1
Hargreaves, D.C.2
Miller, E.L.3
Cui, K.4
Korshunov, A.5
Kool, M.6
Pfister, S.7
Cho, Y.J.8
Zhao, K.9
Crabtree, G.R.10
-
98
-
-
84864492215
-
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
-
T. J. Pugh, S. D. Weeraratne, T. C. Archer, K. DA Pomeranz, D. Auclair, J. Bochicchio, M. O. Carneiro, S. L. Carter, K. Cibulskis, R. L. Erlich, H. Greulich, M. S. Lawrence, N. J. Lennon, A. McKenna, J. Meld rim, A. H. Ramos, M. G. Ross, C Russ, E. Shefler, A. Sivachenko, B. Sogoloff, P. Stojanov, P. Tamayo, J. P. Mesirov, V. Amani, N. Teider, S. Sengupta, J. P. Francois, P. A. Northcott, M. D. Taylor, F. Yu, G. R. Crabtree, A. G. Kautzman, S. B. Gabriel, G. Getz, N. Jager, D. T. Jones, P. Lichter, S. M. Pfister, T. M. Roberts, M. Meyerson, S. L Pomeroy, Y. J. Cho, Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature 488, 106-110 (2012).
-
(2012)
Nature
, vol.488
, pp. 106-110
-
-
Pugh, T.J.1
Weeraratne, S.D.2
Archer, T.C.3
Pomeranz, K.D.A.4
Auclair, D.5
Bochicchio, J.6
Carneiro, M.O.7
Carter, S.L.8
Cibulskis, K.9
Erlich, R.L.10
Greulich, H.11
Lawrence, M.S.12
Lennon, N.J.13
McKenna, A.14
Meldrim, J.15
Ramos, A.H.16
Ross, M.G.17
Russ, C.18
Shefler, E.19
Sivachenko, A.20
Sogoloff, B.21
Stojanov, P.22
Tamayo, P.23
Mesirov, J.P.24
Amani, V.25
Teider, N.26
Sengupta, S.27
Francois, J.P.28
Northcott, P.A.29
Taylor, M.D.30
Yu, F.31
Crabtree, G.R.32
Kautzman, A.G.33
Gabriel, S.B.34
Getz, G.35
Jager, N.36
Jones, D.T.37
Lichter, P.38
Pfister, S.M.39
Roberts, T.M.40
Meyerson, M.41
Pomeroy, S.L.42
Cho, Y.J.43
more..
-
99
-
-
0035801499
-
The chromatin remodelling factor Brg-1 interacts with β-catenin to promote target gene activation
-
N. Barker, A. Hurlstone, H. Musisi, A. Miles, M. Bienz, H. Clevers, The chromatin remodelling factor Brg-1 interacts with β-catenin to promote target gene activation. Embo J 20, 4935-4943 (2001).
-
(2001)
Embo J
, vol.20
, pp. 4935-4943
-
-
Barker, N.1
Hurlstone, A.2
Musisi, H.3
Miles, A.4
Bienz, M.5
Clevers, H.6
-
100
-
-
84887992179
-
Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome
-
T. Davoli, A. W. Xu, K. E. Mengwasser, L. M. Sack, J. C. Yoon, P. J. Park, S. J. Elledge, Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome. Ceil 155, 948-962 (2013).
-
(2013)
Ceil
, vol.155
, pp. 948-962
-
-
Davoli, T.1
Xu, A.W.2
Mengwasser, K.E.3
Sack, L.M.4
Yoon, J.C.5
Park, P.J.6
Elledge, S.J.7
-
101
-
-
84883183357
-
The chromatin remodeller ATRX: A repeat offender in human disease
-
D. Clynes, D. R. Higgs, R. J. Gibbons, The chromatin remodeller ATRX: A repeat offender in human disease. Trends Biochem. Sci. 38, 461-466 (2013).
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 461-466
-
-
Clynes, D.1
Higgs, D.R.2
Gibbons, R.J.3
-
102
-
-
0028939603
-
Mutations in a putative global transcriptional regulator cause X-linked mental retardation with a-thalassemia (ATR-X syndrome)
-
R. J. Gibbons, D. J. Picketts, L. Villard, D. R. Higgs, Mutations in a putative global transcriptional regulator cause X-linked mental retardation with a-thalassemia (ATR-X syndrome). Cell80, 837-845 (1995).
-
(1995)
Cell
, vol.80
, pp. 837-845
-
-
Gibbons, R.J.1
Picketts, D.J.2
Villard, L.3
Higgs, D.R.4
-
103
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
J. Schwartzentruber, A. Korshunov, X. Y. Liu, D. T. Jones, E. Pfaff, K. Jacob, D. Sturm, A. M. Fontebasso, D. A. Quang, M. Tonjes, V. Hovestadt, S. Albrecht, M. Kool, A. Nantel, C. Konermann, A. Lindroth, N. Jager, T. Rausch, M. Ryzhova, J. O. Korbel, T. Hielscher, P. Hauser, M. Garami, A. Klekner, L. Bognar, M. Ebinger, M. U. Schuhmann, W. Scheurlen, A. Pekrun, M. C. Fruhwald, W. Roggendorf, C. Kramm, M. Durken, J. Atkinson, P. Lepage, A. Montpetit, M. Zakrzewska, K. Zakrzewski, P. P. Liberski, Z. Dong, P. Siegel, A. E. Kulozik, M. Zapatka, A. Guha, D. Malkin, J. Felsberg, G. Reifenberger, A. von Deimling, K. Ichimura, V. P. Collins, H. Witt, T. Milde, O. Witt, C. Zhang, P. Castelo-Branco, P. Lichter, D. Faury, U. Tabori, C. Plass, J. Majewski, S. M. Pfister, N. Jabado, Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 482, 226-231 (2012).
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
Jones, D.T.4
Pfaff, E.5
Jacob, K.6
Sturm, D.7
Fontebasso, A.M.8
Quang, D.A.9
Tonjes, M.10
Hovestadt, V.11
Albrecht, S.12
Kool, M.13
Nantel, A.14
Konermann, C.15
Lindroth, A.16
Jager, N.17
Rausch, T.18
Ryzhova, M.19
Korbel, J.O.20
Hielscher, T.21
Hauser, P.22
Garami, M.23
Klekner, A.24
Bognar, L.25
Ebinger, M.26
Schuhmann, M.U.27
Scheurlen, W.28
Pekrun, A.29
Fruhwald, M.C.30
Roggendorf, W.31
Kramm, C.32
Durken, M.33
Atkinson, J.34
Lepage, P.35
Montpetit, A.36
Zakrzewska, M.37
Zakrzewski, K.38
Liberski, P.P.39
Dong, Z.40
Siegel, P.41
Kulozik, A.E.42
Zapatka, M.43
Guha, A.44
Malkin, D.45
Felsberg, J.46
Reifenberger, G.47
Von Deimling, A.48
Ichimura, K.49
Collins, V.P.50
Witt, H.51
Milde, T.52
Witt, O.53
Zhang, C.54
Castelo-Branco, P.55
Lichter, P.56
Faury, D.57
Tabori, U.58
Plass, C.59
Majewski, J.60
Pfister, S.M.61
Jabado, N.62
more..
-
104
-
-
79960063257
-
Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin
-
S. Eustermann, J.C. Yang, M.J. Law, R. Amos, L. M. Chapman, C. Jelinska, D. Garrick, D. Clynes, R. J. Gibbons, D. Rhodes, D. R. Higgs, D. Neuhaus, Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin. Nat. Struct. Mol. Biol. 18, 777-782 (2011).
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 777-782
-
-
Eustermann, S.1
Yang, J.C.2
Law, M.J.3
Amos, R.4
Chapman, L.M.5
Jelinska, C.6
Garrick, D.7
Clynes, D.8
Gibbons, R.J.9
Rhodes, D.10
Higgs, D.R.11
Neuhaus, D.12
-
105
-
-
84866390624
-
Recurrent deletion of CHD1 in prostate cancer with relevance to cell invasiveness
-
S. Huang, Z. G. Gulzar, K. Salari, J. Lapointe, J. D. Brooks, J. R. Pollack, Recurrent deletion of CHD1 in prostate cancer with relevance to cell invasiveness. Oncogene 31, 4164-4170 (2012).
-
(2012)
Oncogene
, vol.31
, pp. 4164-4170
-
-
Huang, S.1
Gulzar, Z.G.2
Salari, K.3
Lapointe, J.4
Brooks, J.D.5
Pollack, J.R.6
-
106
-
-
84865639773
-
Identification of novel CHD1-associated collaborative alterations of genomic structure and functiona assessment of CHD1 in prostate cancer
-
W. Liu, J. Lindberg, G. Sui, J. Luo, L. Egevad, T. Li, C. Xie, M. Wan, S. T. Kim, Z. Wang, A. R. Turner, Z. Zhang, J. Feng, Y. Yan, J. Sun, G. S. Bova, C. M. Ewing, G. Yan, M. Gielzak, S. D. Cramer, R. L. Vessella, S. L. Zheng, H. Gronberg, W. B. Isaacs, J. Xu, Identification of novel CHD1-associated collaborative alterations of genomic structure and functiona assessment of CHD1 in prostate cancer. Oncogene 31, 3939-3948 (2012).
-
(2012)
Oncogene
, vol.31
, pp. 3939-3948
-
-
Liu, W.1
Lindberg, J.2
Sui, G.3
Luo, J.4
Egevad, L.5
Li, T.6
Xie, C.7
Wan, M.8
Kim, S.T.9
Wang, Z.10
Turner, A.R.11
Zhang, Z.12
Feng, J.13
Yan, Y.14
Sun, J.15
Bova, G.S.16
Ewing, C.M.17
Yan, G.18
Gielzak, M.19
Cramer, S.D.20
Vessella, R.L.21
Zheng, S.L.22
Gronberg, H.23
Isaacs, W.B.24
Xu, J.25
more..
-
107
-
-
84877747485
-
CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer
-
L. Burkhardt, S. Fuchs, A. Krohn, S. Masser, M. Mader, M. Kluth, F. Bachmann, H. Huland, T. Steuber, M. Graefen, T. Schlomm, S. Minner, G. Sauter, H. Sirma, R. Simon, CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer. Cancer Res. 73, 2795-2805 (2013).
-
(2013)
Cancer Res.
, vol.73
, pp. 2795-2805
-
-
Burkhardt, L.1
Fuchs, S.2
Krohn, A.3
Masser, S.4
Mader, M.5
Kluth, M.6
Bachmann, F.7
Huland, H.8
Steuber, T.9
Graefen, M.10
Schlomm, T.11
Minner, S.12
Sauter, G.13
Sirma, H.14
Simon, R.15
-
108
-
-
55449092929
-
Drosophila Kismet regulates histone H3 lysine 27 methylation and early elongation by RNA polymerase II
-
S. Srinivasan, K M. Dorighi, J. W. Tamkun, Drosophila Kismet regulates histone H3 lysine 27 methylation and early elongation by RNA polymerase II. PLOS Genet. 4, e1000217 (2008).
-
(2008)
PLOS Genet.
, vol.4
, pp. e1000217
-
-
Srinivasan, S.1
Dorighi, K.M.2
Tamkun, J.W.3
-
109
-
-
84920288664
-
Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth
-
K. H. Kim, C. W. Roberts, Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth. Cancer genetics 207, 365-372 (2014).
-
(2014)
Cancer Genetics
, vol.207
, pp. 365-372
-
-
Kim, K.H.1
Roberts, C.W.2
-
110
-
-
84877324084
-
Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2
-
S. K. Knutson, N. M. Warholic, T. J. Wigle, C. R. Klaus, C. J. Allain, A. Raimondi, S. M. Porter, R. Chesworth, M. P. Moyer, R. A Copeland, V. M. Richon, R. M. Pollock, K W. Kuntz, H. Keilhack, Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2. Proc. Natl. Acad. Sci. U.S.A. 110, 7922-7927 (2013).
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 7922-7927
-
-
Knutson, S.K.1
Warholic, N.M.2
Wigle, T.J.3
Klaus, C.R.4
Allain, C.J.5
Raimondi, A.6
Porter, S.M.7
Chesworth, R.8
Moyer, M.P.9
Copeland, R.A.10
Richon, V.M.11
Pollock, R.M.12
Kuntz, K.W.13
Keilhack, H.14
-
111
-
-
84925502851
-
Synthetic lethality by targeting EZH2 methyltransferase activity in /Ifi/DM-mutated cancers
-
B. G. Bitler, K M. Aird, A. Garipov, H. Li, M. Amatangelo, A. V. Kossenkov, D. C. Schultz, Q. Liu, I. M. Shih, J. R. Conejo-Garcia, D. W. Speicher, R. Zhang, Synthetic lethality by targeting EZH2 methyltransferase activity in /Ifi/DM-mutated cancers. Nat. Med. 21, 231-238 (2015).
-
(2015)
Nat. Med.
, vol.21
, pp. 231-238
-
-
Bitler, B.G.1
Aird, K.M.2
Garipov, A.3
Li, H.4
Amatangelo, M.5
Kossenkov, A.V.6
Schultz, D.C.7
Liu, Q.8
Shih, I.M.9
Conejo-Garcia, J.R.10
Speicher, D.W.11
Zhang, R.12
-
112
-
-
84921318899
-
Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma
-
S. K Knutson, S. Kawano, Y. Minoshima, N. M. Warholic, K C. Huang, Y. Xiao, T. Kadowaki, M. Uesugi, G. Kuznetsov, N. Kumar, T. J. Wigle, C. R. Klaus, C.J. Allain, A. Raimondi, N.J. Waters, J. J. Smith, M. Porter-Scott, R. Chesworth, M. P. Moyer, R A. Copeland, V. M. Richon, T. Uenaka, R. M. Pollock, K W. Kuntz, A. Yokoi, H. Keilhack, Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. Mol. Cancer Ther. 13, 842-854 (2014).
-
(2014)
Mol. Cancer Ther.
, vol.13
, pp. 842-854
-
-
Knutson, S.K.1
Kawano, S.2
Minoshima, Y.3
Warholic, N.M.4
Huang, K.C.5
Xiao, Y.6
Kadowaki, T.7
Uesugi, M.8
Kuznetsov, G.9
Kumar, N.10
Wigle, T.J.11
Klaus, C.R.12
Allain, C.J.13
Raimondi, A.14
Waters, N.J.15
Smith, J.J.16
Porter-Scott, M.17
Chesworth, R.18
Moyer, M.P.19
Copeland, R.A.20
Richon, V.M.21
Uenaka, T.22
Pollock, R.M.23
Kuntz, K.W.24
Yokoi, A.25
Keilhack, H.26
more..
-
113
-
-
84862662420
-
Dynamics and memory of heterochromatin in living cells
-
N. A. Hathaway, O. Bell, C. Hodges, E. L. Miller, D. S. Neel, G. R. Crabtree, Dynamics and memory of heterochromatin in living cells. Cell 149, 1447-1460 (2012).
-
(2012)
Cell
, vol.149
, pp. 1447-1460
-
-
Hathaway, N.A.1
Bell, O.2
Hodges, C.3
Miller, E.L.4
Neel, D.S.5
Crabtree, G.R.6
-
114
-
-
84865173853
-
Dynamics of inherently bounded histone modification domains
-
C. Hodges, G. R Crabtree, Dynamics of inherently bounded histone modification domains. Proc. Natl. Acad. Sci. U.SA 109, 13296-13301 (2012).
-
(2012)
Proc. Natl. Acad. Sci. U.SA
, vol.109
, pp. 13296-13301
-
-
Hodges, C.1
Crabtree, G.R.2
-
115
-
-
0036085460
-
Cellular roles of DNA topoisomerases: A molecular perspective
-
J. C. Wang, Cellular roles of DNA topoisomerases: A molecular perspective. Nat. Rev. Mol. Cell Biol. 3, 430-440 (2002).
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 430-440
-
-
Wang, J.C.1
-
116
-
-
79960676884
-
Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide
-
C. C. Wu, T. K. Li, L. Farh, L. Y. Lin, T. S. Lin, Y. J. Yu, T. J. Yen, C. W. Chiang, N. L. Chan, Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide. Science 333, 459-462 (2011).
-
(2011)
Science
, vol.333
, pp. 459-462
-
-
Wu, C.C.1
Li, T.K.2
Farh, L.3
Lin, L.Y.4
Lin, T.S.5
Yu, Y.J.6
Yen, T.J.7
Chiang, C.W.8
Chan, N.L.9
-
117
-
-
77954187741
-
DNA topoisomerases and their poisoning by anticancer and antibacterial drugs
-
Y. Pommier, E. Leo, H. Zhang, C. Marchand, DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Chem. Biol. 17,421-433 (2010).
-
(2010)
Chem. Biol.
, vol.17
, pp. 421-433
-
-
Pommier, Y.1
Leo, E.2
Zhang, H.3
Marchand, C.4
-
118
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
R. E. Thurman, E. Rynes, R. Humbert, J. Vierstra, M. T. Maurano, E. Haugen, N. C. Sheffield, A. B. Stergachis, H. Wang, B. Vernot, K. Garg, S. John, R. Sandstrom, D. Bates, L. Boatman, T. K Canfield, M. Diegel, D. Dunn, A. K Ebersol, T. Frum, E. Giste, A. K Johnson, E. M. Johnson, T. Kutyavin, B. Lajoie, B. K Lee, K Lee, D. London, D. Lotakis, S. Neph, F. Neri, E. D. Nguyen, H. Qu, A. P. Reynolds, V. Roach, A. Safi, M. E. Sanchez, A. Sanyal, A. Shafer, J. M. Simon, L. Song, S. Vong, M. Weaver, Y. Yan, Z. Zhang, Z. Zhang, B. Lenhard, M. Tewari, M. O. Dorschner, R. S. Hansen, P. A. Navas, G. Stamatoyannopoulos, V. R. Iyer, J. D. Lieb, S. R. Sunyaev, J. M. Akey, P. J. Sabo, R. Kaul, T. S. Furey, J. Dekker, G. E. Crawford, J. A. Stamatoyannopoulos, The accessible chromatin landscape of the human genome. Nature 489, 75-82 (2012).
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
Rynes, E.2
Humbert, R.3
Vierstra, J.4
Maurano, M.T.5
Haugen, E.6
Sheffield, N.C.7
Stergachis, A.B.8
Wang, H.9
Vernot, B.10
Garg, K.11
John, S.12
Sandstrom, R.13
Bates, D.14
Boatman, L.15
Canfield, T.K.16
Diegel, M.17
Dunn, D.18
Ebersol, A.K.19
Frum, T.20
Giste, E.21
Johnson, A.K.22
Johnson, E.M.23
Kutyavin, T.24
Lajoie, B.25
Lee, B.K.26
Lee, K.27
London, D.28
Lotakis, D.29
Neph, S.30
Neri, F.31
Nguyen, E.D.32
Qu, H.33
Reynolds, A.P.34
Roach, V.35
Safi, A.36
Sanchez, M.E.37
Sanyal, A.38
Shafer, A.39
Simon, J.M.40
Song, L.41
Vong, S.42
Weaver, M.43
Yan, Y.44
Zhang, Z.45
Zhang, Z.46
Lenhard, B.47
Tewari, M.48
Dorschner, M.O.49
Hansen, R.S.50
Navas, P.A.51
Stamatoyannopoulos, G.52
Iyer, V.R.53
Lieb, J.D.54
Sunyaev, S.R.55
Akey, J.M.56
Sabo, P.J.57
Kaul, R.58
Furey, T.S.59
Dekker, J.60
Crawford, G.E.61
Stamatoyannopoulos, J.A.62
more..
-
119
-
-
79961225321
-
Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase i to enhance recruitment of RNA Pol II in budding yeast
-
A. S. Sperling, K S. Jeong, T. Kitada, M. Grunstein, Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast. Proc Natl. Acad. Sci. U.SA 108, 12693-12698 (2011).
-
(2011)
Proc Natl. Acad. Sci. U.SA
, vol.108
, pp. 12693-12698
-
-
Sperling, A.S.1
Jeong, K.S.2
Kitada, T.3
Grunstein, M.4
-
120
-
-
84927547043
-
EZH2 inhibition sensitizes BRGI and EGFR mutant lung tumours to Topoll inhibitors
-
C. M. Fillmore, C. Xu, P.T. Desai, J. M. Berry, S. P. Rowbotham, Y.J. Lin, H. Zhang, V. E. Marquez, P. S. Hammerman, K K Wong, C. F. Kim, EZH2 inhibition sensitizes BRGI and EGFR mutant lung tumours to Topoll inhibitors. Nature 520, 239-242 (2015).
-
(2015)
Nature
, vol.520
, pp. 239-242
-
-
Fillmore, C.M.1
Xu, C.2
Desai, P.T.3
Berry, J.M.4
Rowbotham, S.P.5
Lin, Y.J.6
Zhang, H.7
Marquez, V.E.8
Hammerman, P.S.9
Wong, K.K.10
Kim, C.F.11
-
121
-
-
0037414868
-
Regulation of chromatin remodeling by inositol polyphosphates
-
D. J. Steger, E. S. Haswell, A. L. Miller, S. R. Wente, E. K O'Shea, Regulation of chromatin remodeling by inositol polyphosphates. Science 299, 114-116 (2003).
-
(2003)
Science
, vol.299
, pp. 114-116
-
-
Steger, D.J.1
Haswell, E.S.2
Miller, A.L.3
Wente, S.R.4
O'Shea, E.K.5
-
122
-
-
58149398623
-
Translation of the Philadelphia chromosome into therapy for CML
-
B. J. Druker, Translation of the Philadelphia chromosome into therapy for CML. Blood 112, 4808-4817 (2008).
-
(2008)
Blood
, vol.112
, pp. 4808-4817
-
-
Druker, B.J.1
|