-
1
-
-
79959267832
-
Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker
-
Takawa M, Masuda K, Kunizaki M, Daigo Y, Takagi K, Iwai Y, Cho HS, Toyokawa G, Yamane Y, Maejima K, et al. (2011). Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker. Cancer Sci 102, 1298-1305.
-
(2011)
Cancer Sci
, vol.102
, pp. 1298-1305
-
-
Takawa, M.1
Masuda, K.2
Kunizaki, M.3
Daigo, Y.4
Takagi, K.5
Iwai, Y.6
Cho, H.S.7
Toyokawa, G.8
Yamane, Y.9
Maejima, K.10
-
2
-
-
84867632489
-
A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells
-
Knutson SK, Wigle TJ, Warholic NM, Sneeringer CJ, Allain CJ, Klaus CR, Sacks JD, Raimondi A, Majer CR, Song J, et al. (2012). A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells. Nat Chem Biol 8, 890-896.
-
(2012)
Nat Chem Biol
, vol.8
, pp. 890-896
-
-
Knutson, S.K.1
Wigle, T.J.2
Warholic, N.M.3
Sneeringer, C.J.4
Allain, C.J.5
Klaus, C.R.6
Sacks, J.D.7
Raimondi, A.8
Majer, C.R.9
Song, J.10
-
3
-
-
84870573126
-
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
-
McCabe MT, Ott HM, Ganji G, Korenchuk S, Thompson C, Van Aller GS, Liu Y, Graves AP, Della Pietra A III, Diaz E, et al. (2012). EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations. Nature 492, 108-112.
-
(2012)
Nature
, vol.492
, pp. 108-112
-
-
McCabe, M.T.1
Ott, H.M.2
Ganji, G.3
Korenchuk, S.4
Thompson, C.5
van Aller, G.S.6
Liu, Y.7
Graves, A.P.8
della Pietra, A.I.I.I.9
Diaz, E.10
-
4
-
-
0033556404
-
Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates
-
Schiltz RL, Mizzen CA, Vassilev A, Cook RG, Allis CD, and Nakatani Y (1999). Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates. J Biol Chem 274, 1189-1192.
-
(1999)
J Biol Chem
, vol.274
, pp. 1189-1192
-
-
Schiltz, R.L.1
Mizzen, C.A.2
Vassilev, A.3
Cook, R.G.4
Allis, C.D.5
Nakatani, Y.6
-
5
-
-
0034839973
-
Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin
-
Suka N, Suka Y, Carmen AA, Wu J, and Grunstein M (2001). Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin. Mol Cell 8, 473-479.
-
(2001)
Mol Cell
, vol.8
, pp. 473-479
-
-
Suka, N.1
Suka, Y.2
Carmen, A.A.3
Wu, J.4
Grunstein, M.5
-
6
-
-
0038293152
-
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
-
Cheung WL, Ajiro K, Samejima K, Kloc M, Cheung P, Mizzen CA, Beeser A, Etkin LD, Chernoff J, Earnshaw WC, et al. (2003). Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 113, 507-517.
-
(2003)
Cell
, vol.113
, pp. 507-517
-
-
Cheung, W.L.1
Ajiro, K.2
Samejima, K.3
Kloc, M.4
Cheung, P.5
Mizzen, C.A.6
Beeser, A.7
Etkin, L.D.8
Chernoff, J.9
Earnshaw, W.C.10
-
7
-
-
27944454433
-
Monoubiquitination of human histone H2B: The factors involved and their roles in HOX gene regulation
-
Zhu B, Zheng Y, Pham AD, Mandal SS, Erdjument-Bromage H, Tempst P, and Reinberg D (2005). Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. Mol Cell 20, 601-611.
-
(2005)
Mol Cell
, vol.20
, pp. 601-611
-
-
Zhu, B.1
Zheng, Y.2
Pham, A.D.3
Mandal, S.S.4
Erdjument-Bromage, H.5
Tempst, P.6
Reinberg, D.7
-
8
-
-
33645879818
-
Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications
-
Nathan D, Ingvarsdottir K, Sterner DE, Bylebyl GR, Dokmanovic M, Dorsey JA, Whelan KA, Krsmanovic M, Lane WS, Meluh PB, et al. (2006). Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. Genes Dev 20, 966-976.
-
(2006)
Genes Dev
, vol.20
, pp. 966-976
-
-
Nathan, D.1
Ingvarsdottir, K.2
Sterner, D.E.3
Bylebyl, G.R.4
Dokmanovic, M.5
Dorsey, J.A.6
Whelan, K.A.7
Krsmanovic, M.8
Lane, W.S.9
Meluh, P.B.10
-
9
-
-
0037019333
-
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
-
Sun ZW and Allis CD (2002). Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418, 104-108.
-
(2002)
Nature
, vol.418
, pp. 104-108
-
-
Sun, Z.W.1
Allis, C.D.2
-
10
-
-
43149122898
-
Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells
-
Minsky N, Shema E, Field Y, Schuster M, Segal E, and Oren M (2008). Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells. Nat Cell Biol 10, 483-488.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 483-488
-
-
Minsky, N.1
Shema, E.2
Field, Y.3
Schuster, M.4
Segal, E.5
Oren, M.6
-
11
-
-
68249128223
-
CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3′-end processing
-
Pirngruber J, Shchebet A, Schreiber L, Shema E, Minsky N, Chapman RD, Eick D, Aylon Y, Oren M, and Johnsen SA (2009). CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3′-end processing. EMBO Rep 10, 894-900.
-
(2009)
EMBO Rep
, vol.10
, pp. 894-900
-
-
Pirngruber, J.1
Shchebet, A.2
Schreiber, L.3
Shema, E.4
Minsky, N.5
Chapman, R.D.6
Eick, D.7
Aylon, Y.8
Oren, M.9
Johnsen, S.A.10
-
12
-
-
28444463638
-
The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions
-
Kim J, Hake SB, and Roeder RG (2005). The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions. Mol Cell 20, 759-770.
-
(2005)
Mol Cell
, vol.20
, pp. 759-770
-
-
Kim, J.1
Hake, S.B.2
Roeder, R.G.3
-
13
-
-
78751515133
-
Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction
-
Fierz B, Chatterjee C, McGinty RK, Bar-Dagan M, Raleigh DP, and Muir TW (2011). Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction. Nat Chem Biol 7, 113-119.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 113-119
-
-
Fierz, B.1
Chatterjee, C.2
McGinty, R.K.3
Bar-Dagan, M.4
Raleigh, D.P.5
Muir, T.W.6
-
14
-
-
84861968321
-
RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation
-
Fuchs G, Shema E, Vesterman R, Kotler E, Wolchinsky Z, Wilder S, Golomb L, Pribluda A, Zhang F, Haj-Yahya M, et al. (2012). RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation. Mol Cell 46, 662-673.
-
(2012)
Mol Cell
, vol.46
, pp. 662-673
-
-
Fuchs, G.1
Shema, E.2
Vesterman, R.3
Kotler, E.4
Wolchinsky, Z.5
Wilder, S.6
Golomb, L.7
Pribluda, A.8
Zhang, F.9
Haj-Yahya, M.10
-
15
-
-
4143074854
-
SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells
-
Hamamoto R, Furukawa Y, Morita M, Iimura Y, Silva FP, Li M, Yagyu R, and Nakamura Y (2004). SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Nat Cell Biol 6, 731-740.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 731-740
-
-
Hamamoto, R.1
Furukawa, Y.2
Morita, M.3
Iimura, Y.4
Silva, F.P.5
Li, M.6
Yagyu, R.7
Nakamura, Y.8
-
16
-
-
33644929027
-
Enhanced SMYD3 expression is essential for the growth of breast cancer cells
-
Hamamoto R, Silva FP, Tsuge M, Nishidate T, Katagiri T, Nakamura Y, and Furukawa Y (2006). Enhanced SMYD3 expression is essential for the growth of breast cancer cells. Cancer Sci 97, 113-118.
-
(2006)
Cancer Sci
, vol.97
, pp. 113-118
-
-
Hamamoto, R.1
Silva, F.P.2
Tsuge, M.3
Nishidate, T.4
Katagiri, T.5
Nakamura, Y.6
Furukawa, Y.7
-
17
-
-
84867026199
-
Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B
-
Cho HS, Shimazu T, Toyokawa G, Daigo Y, Maehara Y, Hayami S, Ito A, Masuda K, Ikawa N, Field HI, et al. (2012). Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. Nat Commun 3, 1072.
-
(2012)
Nat Commun
, vol.3
, pp. 1072
-
-
Cho, H.S.1
Shimazu, T.2
Toyokawa, G.3
Daigo, Y.4
Maehara, Y.5
Hayami, S.6
Ito, A.7
Masuda, K.8
Ikawa, N.9
Field, H.I.10
-
18
-
-
79551519643
-
Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells
-
Cho HS, Suzuki T, Dohmae N, Hayami S, Unoki M, Yoshimatsu M, Toyokawa G, Takawa M, Chen T, Kurash JK, et al. (2011). Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells. Cancer Res 71, 655-660.
-
(2011)
Cancer Res
, vol.71
, pp. 655-660
-
-
Cho, H.S.1
Suzuki, T.2
Dohmae, N.3
Hayami, S.4
Unoki, M.5
Yoshimatsu, M.6
Toyokawa, G.7
Takawa, M.8
Chen, T.9
Kurash, J.K.10
-
19
-
-
84863579070
-
Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression
-
Takawa M, Cho HS, Hayami S, Toyokawa G, Kogure M, Yamane Y, Iwai Y, Maejima K, Ueda K, Masuda A, et al. (2012). Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. Cancer Res 72, 3217-3227.
-
(2012)
Cancer Res
, vol.72
, pp. 3217-3227
-
-
Takawa, M.1
Cho, H.S.2
Hayami, S.3
Toyokawa, G.4
Kogure, M.5
Yamane, Y.6
Iwai, Y.7
Maejima, K.8
Ueda, K.9
Masuda, A.10
-
20
-
-
78649815150
-
Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers
-
Hayami S, Kelly JD, Cho HS, Yoshimatsu M, Unoki M, Tsunoda T, Field HI, Neal DE, Yamaue H, Ponder BA, et al. (2011). Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. Int J Cancer 128, 574-586.
-
(2011)
Int J Cancer
, vol.128
, pp. 574-586
-
-
Hayami, S.1
Kelly, J.D.2
Cho, H.S.3
Yoshimatsu, M.4
Unoki, M.5
Tsunoda, T.6
Field, H.I.7
Neal, D.E.8
Yamaue, H.9
Ponder, B.A.10
-
21
-
-
84878972592
-
Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G1/S transition
-
Kogure M, Takawa M, Cho HS, Toyokawa G, Hayashi K, Tsunoda T, Kobayashi T, Daigo Y, Sugiyama M, Atomi Y, et al. (2013). Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G1/S transition. Cancer Lett 336, 76-84.
-
(2013)
Cancer Lett
, vol.336
, pp. 76-84
-
-
Kogure, M.1
Takawa, M.2
Cho, H.S.3
Toyokawa, G.4
Hayashi, K.5
Tsunoda, T.6
Kobayashi, T.7
Daigo, Y.8
Sugiyama, M.9
Atomi, Y.10
-
22
-
-
67649884743
-
Fast and accurate short read alignment with Burrows-Wheeler transform
-
Li H and Durbin R (2009). Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760.
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
23
-
-
53849146020
-
Model-based analysis of ChIPSeq (MACS)
-
Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, et al. (2008). Model-based analysis of ChIPSeq (MACS). Genome Biol 9, R137.
-
(2008)
Genome Biol
, vol.9
-
-
Zhang, Y.1
Liu, T.2
Meyer, C.A.3
Eeckhoute, J.4
Johnson, D.S.5
Bernstein, B.E.6
Nusbaum, C.7
Myers, R.M.8
Brown, M.9
Li, W.10
-
24
-
-
80051992044
-
Using MACS to identify peaks from ChIPSeq data
-
2.14.1-2.14.14. Chapter 2, Unit 2 14
-
Feng J, Liu T, and Zhang Y (2011). Using MACS to identify peaks from ChIPSeq data. Curr Protoc Bioinformatics 34, 2.14.1-2.14.14. Chapter 2, Unit 2 14.
-
(2011)
Curr Protoc Bioinformatics
, vol.34
-
-
Feng, J.1
Liu, T.2
Zhang, Y.3
-
26
-
-
77949468885
-
Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: Involvement in the proliferation of cancer cells through the E2F/RB pathway
-
Hayami S, Yoshimatsu M, Veerakumarasivam A, Unoki M, Iwai Y, Tsunoda T, Field HI, Kelly JD, Neal DE, Yamaue H, et al. (2010). Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway. Mol Cancer 9, 59.
-
(2010)
Mol Cancer
, vol.9
, pp. 59
-
-
Hayami, S.1
Yoshimatsu, M.2
Veerakumarasivam, A.3
Unoki, M.4
Iwai, Y.5
Tsunoda, T.6
Field, H.I.7
Kelly, J.D.8
Neal, D.E.9
Yamaue, H.10
-
27
-
-
78649638594
-
Dysregulation of PRMT1 and PRMT6, type I arginine methyltransferases, is involved in various types of human cancers
-
Yoshimatsu M, Toyokawa G, Hayami S, Unoki M, Tsunoda T, Field HI, Kelly JD, Neal DE, Maehara Y, Ponder BA, et al. (2011). Dysregulation of PRMT1 and PRMT6, type I arginine methyltransferases, is involved in various types of human cancers. Int J Cancer 128, 562-573.
-
(2011)
Int J Cancer
, vol.128
, pp. 562-573
-
-
Yoshimatsu, M.1
Toyokawa, G.2
Hayami, S.3
Unoki, M.4
Tsunoda, T.5
Field, H.I.6
Kelly, J.D.7
Neal, D.E.8
Maehara, Y.9
Ponder, B.A.10
-
28
-
-
33646691283
-
Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II
-
Pavri R, Zhu B, Li G, Trojer P, Mandal S, Shilatifard A, and Reinberg D (2006). Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell 125, 703-717.
-
(2006)
Cell
, vol.125
, pp. 703-717
-
-
Pavri, R.1
Zhu, B.2
Li, G.3
Trojer, P.4
Mandal, S.5
Shilatifard, A.6
Reinberg, D.7
-
29
-
-
79951974992
-
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks
-
Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, et al. (2011). Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol Cell 41, 529-542.
-
(2011)
Mol Cell
, vol.41
, pp. 529-542
-
-
Moyal, L.1
Lerenthal, Y.2
Gana-Weisz, M.3
Mass, G.4
So, S.5
Wang, S.Y.6
Eppink, B.7
Chung, Y.M.8
Shalev, G.9
Shema, E.10
-
30
-
-
84855864819
-
H2B ubiquitylation controls the formation of export-competent mRNP
-
Vitaliano-Prunier A, Babour A, Hérissant L, Apponi L, Margaritis T, Holstege FC, Corbett AH, Gwizdek C, and Dargemont C (2012). H2B ubiquitylation controls the formation of export-competent mRNP. Mol Cell 45, 132-139.
-
(2012)
Mol Cell
, vol.45
, pp. 132-139
-
-
Vitaliano-Prunier, A.1
Babour, A.2
Hérissant, L.3
Apponi, L.4
Margaritis, T.5
Holstege, F.C.6
Corbett, A.H.7
Gwizdek, C.8
Dargemont, C.9
-
31
-
-
38149078715
-
The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression
-
Zhang XY, Varthi M, Sykes SM, Phillips C, Warzecha C, Zhu W, Wyce A, Thorne AW, Berger SL, and McMahon SB (2008). The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Mol Cell 29, 102-111.
-
(2008)
Mol Cell
, vol.29
, pp. 102-111
-
-
Zhang, X.Y.1
Varthi, M.2
Sykes, S.M.3
Phillips, C.4
Warzecha, C.5
Zhu, W.6
Wyce, A.7
Thorne, A.W.8
Berger, S.L.9
McMahon, S.B.10
-
32
-
-
53549112774
-
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression
-
Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, et al. (2008). The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes Dev 22, 2664-2676.
-
(2008)
Genes Dev
, vol.22
, pp. 2664-2676
-
-
Shema, E.1
Tirosh, I.2
Aylon, Y.3
Huang, J.4
Ye, C.5
Moskovits, N.6
Raver-Shapira, N.7
Minsky, N.8
Pirngruber, J.9
Tarcic, G.10
-
33
-
-
79955946995
-
RNF20 inhibits TFIISfacilitated transcriptional elongation to suppress pro-oncogenic gene expression
-
Shema E, Kim J, Roeder RG, and Oren M (2011). RNF20 inhibits TFIISfacilitated transcriptional elongation to suppress pro-oncogenic gene expression. Mol Cell 42, 477-488.
-
(2011)
Mol Cell
, vol.42
, pp. 477-488
-
-
Shema, E.1
Kim, J.2
Roeder, R.G.3
Oren, M.4
-
34
-
-
84860187274
-
Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability
-
Chernikova SB, Razorenova OV, Higgins JP, Sishc BJ, Nicolau M, Dorth JA, Chernikova DA, Kwok S, Brooks JD, Bailey SM, et al. (2012). Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability. Cancer Res 72, 2111-2119.
-
(2012)
Cancer Res
, vol.72
, pp. 2111-2119
-
-
Chernikova, S.B.1
Razorenova, O.V.2
Higgins, J.P.3
Sishc, B.J.4
Nicolau, M.5
Dorth, J.A.6
Chernikova, D.A.7
Kwok, S.8
Brooks, J.D.9
Bailey, S.M.10
-
35
-
-
84856107676
-
The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination
-
Hahn MA, Dickson KA, Jackson S, Clarkson A, Gill AJ, and Marsh DJ (2012). The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination. Hum Mol Genet 21, 559-568.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 559-568
-
-
Hahn, M.A.1
Dickson, K.A.2
Jackson, S.3
Clarkson, A.4
Gill, A.J.5
Marsh, D.J.6
-
36
-
-
80052248649
-
Estrogendependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B
-
Prenzel T, Begus-Nahrmann Y, Kramer F, Hennion M, Hsu C, Gorsler T, Hintermair C, Eick D, Kremmer E, Simons M, et al. (2011). Estrogendependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B. Cancer Res 71, 5739-5753.
-
(2011)
Cancer Res
, vol.71
, pp. 5739-5753
-
-
Prenzel, T.1
Begus-Nahrmann, Y.2
Kramer, F.3
Hennion, M.4
Hsu, C.5
Gorsler, T.6
Hintermair, C.7
Eick, D.8
Kremmer, E.9
Simons, M.10
-
37
-
-
0029860899
-
Structural and functional characterization of human potassium channel subunit β1 (KCNA1B)
-
Leicher T, Roeper J, Weber K, Wang X, and Pongs O (1996). Structural and functional characterization of human potassium channel subunit β1 (KCNA1B). Neuropharmacology 35, 787-795.
-
(1996)
Neuropharmacology
, vol.35
, pp. 787-795
-
-
Leicher, T.1
Roeper, J.2
Weber, K.3
Wang, X.4
Pongs, O.5
-
38
-
-
0030021295
-
Localization of two potassium channel β subunit genes, KCNA1B and KCNA2B
-
Schultz D, Litt M, Smith L, Thayer M, and McCormack K (1996). Localization of two potassium channel β subunit genes, KCNA1B and KCNA2B. Genomics 31, 389-391.
-
(1996)
Genomics
, vol.31
, pp. 389-391
-
-
Schultz, D.1
Litt, M.2
Smith, L.3
Thayer, M.4
McCormack, K.5
-
39
-
-
3242722919
-
RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
-
Di Marcotullio L, Ferretti E, De Smaele E, Argenti B, Mincione C, Zazzeroni F, Gallo R, Masuelli L, Napolitano M, Maroder M, et al. (2004). RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma. Proc Natl Acad Sci USA 101, 10833-10838.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10833-10838
-
-
Di Marcotullio, L.1
Ferretti, E.2
de Smaele, E.3
Argenti, B.4
Mincione, C.5
Zazzeroni, F.6
Gallo, R.7
Masuelli, L.8
Napolitano, M.9
Maroder, M.10
-
40
-
-
77954051861
-
The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors
-
Mancarelli MM, Zazzeroni F, Ciccocioppo L, Capece D, Po A, Murgo S, Di Camillo R, Rinaldi C, Ferretti E, Gulino A, et al. (2010). The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors. Mol Cancer 9, 172.
-
(2010)
Mol Cancer
, vol.9
, pp. 172
-
-
Mancarelli, M.M.1
Zazzeroni, F.2
Ciccocioppo, L.3
Capece, D.4
Po, A.5
Murgo, S.6
Di Camillo, R.7
Rinaldi, C.8
Ferretti, E.9
Gulino, A.10
-
41
-
-
77951091450
-
Pro-apoptotic and antiproliferative activity of human KCNRG, a putative tumor suppressor in 13q14 region
-
Birerdinc A, Nohelty E, Marakhonov A, Manyam G, Panov I, Coon S, Nikitin E, Skoblov M, Chandhoke V, and Baranova A (2010). Pro-apoptotic and antiproliferative activity of human KCNRG, a putative tumor suppressor in 13q14 region. Tumour Biol 31, 33-45.
-
(2010)
Tumour Biol
, vol.31
, pp. 33-45
-
-
Birerdinc, A.1
Nohelty, E.2
Marakhonov, A.3
Manyam, G.4
Panov, I.5
Coon, S.6
Nikitin, E.7
Skoblov, M.8
Chandhoke, V.9
Baranova, A.10
-
42
-
-
0037468613
-
A new human gene KCNRG encoding potassium channel regulating protein is a cancer suppressor gene candidate located in 13q14.3
-
Ivanov DV, Tyazhelova TV, Lemonnier L, Kononenko N, Pestova AA, Nikitin EA, Prevarskaya N, Skryma R, Panchin YV, Yankovsky NK, et al. (2003). A new human gene KCNRG encoding potassium channel regulating protein is a cancer suppressor gene candidate located in 13q14.3. FEBS Lett 539, 156-160.
-
(2003)
FEBS Lett
, vol.539
, pp. 156-160
-
-
Ivanov, D.V.1
Tyazhelova, T.V.2
Lemonnier, L.3
Kononenko, N.4
Pestova, A.A.5
Nikitin, E.A.6
Prevarskaya, N.7
Skryma, R.8
Panchin, Y.V.9
Yankovsky, N.K.10
-
43
-
-
0034984899
-
Verapamil inhibits proliferation of LNCaP human prostate cancer cells influencing K+ channel gating
-
Rybalchenko V, Prevarskaya N, Van Coppenolle F, Legrand G, Lemonnier L, Le Bourhis X, and Skryma R (2001). Verapamil inhibits proliferation of LNCaP human prostate cancer cells influencing K+ channel gating. Mol Pharmacol 59, 1376-1387.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 1376-1387
-
-
Rybalchenko, V.1
Prevarskaya, N.2
van Coppenolle, F.3
Legrand, G.4
Lemonnier, L.5
Le Bourhis, X.6
Skryma, R.7
-
44
-
-
0028965645
-
Potassium and calcium channels in lymphocytes
-
Lewis RS and Cahalan MD (1995). Potassium and calcium channels in lymphocytes. Annu Rev Immunol 13, 623-653.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 623-653
-
-
Lewis, R.S.1
Cahalan, M.D.2
-
45
-
-
59349115177
-
Chemical mechanisms of histone lysine and arginine modifications
-
Smith BC and Denu JM (2009). Chemical mechanisms of histone lysine and arginine modifications. Biochim Biophys Acta 1789, 45-57.
-
(2009)
Biochim Biophys Acta
, vol.1789
, pp. 45-57
-
-
Smith, B.C.1
Denu, J.M.2
-
46
-
-
0025924179
-
Different forms of Go alpha mRNA arise by alternative splicing of transcripts from a single gene on human chromosome 16
-
Murtagh JJ Jr, Eddy R, Shows TB, Moss J, and Vaughan M (1991). Different forms of Go alpha mRNA arise by alternative splicing of transcripts from a single gene on human chromosome 16. Mol Cell Biol 11, 1146-1155.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 1146-1155
-
-
Murtagh Jr., J.J.1
Eddy, R.2
Shows, T.B.3
Moss, J.4
Vaughan, M.5
-
47
-
-
79958287784
-
Molecular basis of a novel oncogenic mutation in GNAO1
-
Garcia-Marcos M, Ghosh P, and Farquhar MG (2011). Molecular basis of a novel oncogenic mutation in GNAO1. Oncogene 30, 2691-2696.
-
(2011)
Oncogene
, vol.30
, pp. 2691-2696
-
-
Garcia-Marcos, M.1
Ghosh, P.2
Farquhar, M.G.3
-
48
-
-
77955660663
-
Diverse somatic mutation patterns and pathway alterations in human cancers
-
Kan Z, Jaiswal BS, Stinson J, Janakiraman V, Bhatt D, Stern HM, Yue P, Haverty PM, Bourgon R, Zheng J, et al. (2010). Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 466, 869-873.
-
(2010)
Nature
, vol.466
, pp. 869-873
-
-
Kan, Z.1
Jaiswal, B.S.2
Stinson, J.3
Janakiraman, V.4
Bhatt, D.5
Stern, H.M.6
Yue, P.7
Haverty, P.M.8
Bourgon, R.9
Zheng, J.10
-
49
-
-
77950855142
-
Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-κB activation in airway epithelium and promotes lung inflammation and tumorigenesis
-
Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, et al. (2010). Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-κB activation in airway epithelium and promotes lung inflammation and tumorigenesis. Cancer Prev Res (Phila) 3, 424-437.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 424-437
-
-
Deng, J.1
Fujimoto, J.2
Ye, X.F.3
Men, T.Y.4
van Pelt, C.S.5
Chen, Y.L.6
Lin, X.F.7
Kadara, H.8
Tao, Q.9
Lotan, D.10
-
50
-
-
64549101639
-
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability
-
Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Kim SS, Ahn CH, Yoo NJ, and Lee SH (2009). Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. J Pathol 217, 702-706.
-
(2009)
J Pathol
, vol.217
, pp. 702-706
-
-
Kang, M.R.1
Kim, M.S.2
Oh, J.E.3
Kim, Y.R.4
Song, S.Y.5
Kim, S.S.6
Ahn, C.H.7
Yoo, N.J.8
Lee, S.H.9
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