-
1
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J., et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005, 23:479-490.
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
-
2
-
-
53749093767
-
The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'?
-
Moussion C., et al. The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'?. PLoS ONE 2008, 3:e3331.
-
(2008)
PLoS ONE
, vol.3
, pp. e3331
-
-
Moussion, C.1
-
3
-
-
33846101552
-
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo
-
Carriere V., et al. IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:282-287.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 282-287
-
-
Carriere, V.1
-
4
-
-
84859378165
-
Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: in situ analysis using a novel Il-33-LacZ gene trap reporter strain
-
Pichery M., et al. Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: in situ analysis using a novel Il-33-LacZ gene trap reporter strain. J. Immunol. 2012, 188:3488-3495.
-
(2012)
J. Immunol.
, vol.188
, pp. 3488-3495
-
-
Pichery, M.1
-
5
-
-
84920950343
-
IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy
-
Cayrol C., Girard J.P. IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy. Curr. Opin. Immunol. 2014, 31C:31-37.
-
(2014)
Curr. Opin. Immunol.
, vol.31C
, pp. 31-37
-
-
Cayrol, C.1
Girard, J.P.2
-
6
-
-
79955040263
-
The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses
-
Kouzaki H., et al. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J. Immunol. 2011, 186:4375-4387.
-
(2011)
J. Immunol.
, vol.186
, pp. 4375-4387
-
-
Kouzaki, H.1
-
7
-
-
84857484469
-
Interleukin 33 as a mechanically responsive cytokine secreted by living cells
-
Kakkar R., et al. Interleukin 33 as a mechanically responsive cytokine secreted by living cells. J. Biol. Chem. 2012, 287:6941-6948.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 6941-6948
-
-
Kakkar, R.1
-
8
-
-
84859215601
-
Up-regulation of IL-33 expression in various types of murine cells by IL-3 and IL-4
-
Zhao W.H., Hu Z.Q. Up-regulation of IL-33 expression in various types of murine cells by IL-3 and IL-4. Cytokine 2012, 58:267-273.
-
(2012)
Cytokine
, vol.58
, pp. 267-273
-
-
Zhao, W.H.1
Hu, Z.Q.2
-
9
-
-
84867859899
-
Regulation of IL-33 expression by IFN-γ and tumor necrosis factor-α in normal human epidermal keratinocytes
-
Meephansan J., et al. Regulation of IL-33 expression by IFN-γ and tumor necrosis factor-α in normal human epidermal keratinocytes. J. Invest. Dermatol. 2012, 132:2593-2600.
-
(2012)
J. Invest. Dermatol.
, vol.132
, pp. 2593-2600
-
-
Meephansan, J.1
-
10
-
-
0024404517
-
A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor
-
Tominaga S. A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor. FEBS Lett. 1989, 258:301-304.
-
(1989)
FEBS Lett.
, vol.258
, pp. 301-304
-
-
Tominaga, S.1
-
11
-
-
0008519249
-
Serum- and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen
-
Klemenz R., et al. Serum- and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen. Proc. Natl. Acad. Sci. U.S.A. 1989, 86:5708-5712.
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 5708-5712
-
-
Klemenz, R.1
-
12
-
-
0032499678
-
T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function
-
Löhning M., et al. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:6930-6935.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6930-6935
-
-
Löhning, M.1
-
13
-
-
2642610290
-
Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells
-
Xu D., et al. Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J. Exp. Med. 1998, 187:787-794.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 787-794
-
-
Xu, D.1
-
14
-
-
18244418305
-
+ T cells from schistosome egg-induced granulomas: analysis of Th cell cytokine coexpression ex vivo
-
+ T cells from schistosome egg-induced granulomas: analysis of Th cell cytokine coexpression ex vivo. J. Immunol. 1999, 162:3882-3889.
-
(1999)
J. Immunol.
, vol.162
, pp. 3882-3889
-
-
Löhning, M.1
-
15
-
-
0033523665
-
Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses
-
Coyle A.J., et al. Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. J. Exp. Med. 1999, 190:895-902.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 895-902
-
-
Coyle, A.J.1
-
16
-
-
0032212250
-
The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors
-
Moritz D.R., et al. The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors. J. Immunol. 1998, 161:4866-4874.
-
(1998)
J. Immunol.
, vol.161
, pp. 4866-4874
-
-
Moritz, D.R.1
-
17
-
-
0031811882
-
GATA-dependent expression of the interleukin-1 receptor-related T1 gene in mast cells
-
Gachter T., et al. GATA-dependent expression of the interleukin-1 receptor-related T1 gene in mast cells. Mol. Cell. Biol. 1998, 18:5320-5331.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 5320-5331
-
-
Gachter, T.1
-
18
-
-
0030039490
-
Transcription of the interleukin-1 receptor-related T1 gene is initiated at different promoters in mast cells and fibroblasts
-
Gachter T., et al. Transcription of the interleukin-1 receptor-related T1 gene is initiated at different promoters in mast cells and fibroblasts. J. Biol. Chem. 1996, 271:124-129.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 124-129
-
-
Gachter, T.1
-
19
-
-
0031861312
-
Expression analysis of the soluble and membrane-associated forms of the interleukin-1 receptor-related T1 protein in primary mast cells and fibroblasts
-
Moritz D.R., et al. Expression analysis of the soluble and membrane-associated forms of the interleukin-1 receptor-related T1 protein in primary mast cells and fibroblasts. Hybridoma 1998, 17:107-116.
-
(1998)
Hybridoma
, vol.17
, pp. 107-116
-
-
Moritz, D.R.1
-
20
-
-
85027948313
-
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
-
Monticelli L.A., et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat. Immunol. 2011, 12:1045-1054.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 1045-1054
-
-
Monticelli, L.A.1
-
21
-
-
80054889051
-
Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
-
Mjosberg J.M., et al. Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat. Immunol. 2011, 12:1055-1062.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 1055-1062
-
-
Mjosberg, J.M.1
-
22
-
-
77951817855
-
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
-
Neill D.R., et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 2010, 464:1367-1370.
-
(2010)
Nature
, vol.464
, pp. 1367-1370
-
-
Neill, D.R.1
-
23
-
-
75749122181
-
+ lymphoid cells
-
+ lymphoid cells. Nature 2010, 463:540-544.
-
(2010)
Nature
, vol.463
, pp. 540-544
-
-
Moro, K.1
-
24
-
-
77951817294
-
H2 cytokine responses
-
H2 cytokine responses. Nature 2010, 464:1362-1366.
-
(2010)
Nature
, vol.464
, pp. 1362-1366
-
-
Saenz, S.A.1
-
25
-
-
61849117309
-
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33
-
Pecaric-Petkovic T., et al. Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. Blood 2009, 113:1526-1534.
-
(2009)
Blood
, vol.113
, pp. 1526-1534
-
-
Pecaric-Petkovic, T.1
-
26
-
-
44649129170
-
A novel IL-1 family cytokine, IL-33, potently activates human eosinophils
-
Cherry W.B., et al. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. J. Allergy Clin. Immunol. 2008, 121:1484-1490.
-
(2008)
J. Allergy Clin. Immunol.
, vol.121
, pp. 1484-1490
-
-
Cherry, W.B.1
-
27
-
-
48449089903
-
IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells
-
Smithgall M.D., et al. IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells. Int. Immunol. 2008, 20:1019-1030.
-
(2008)
Int. Immunol.
, vol.20
, pp. 1019-1030
-
-
Smithgall, M.D.1
-
28
-
-
58149257537
-
An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor
-
Suzukawa M., et al. An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor. J. Immunol. 2008, 181:5981-5989.
-
(2008)
J. Immunol.
, vol.181
, pp. 5981-5989
-
-
Suzukawa, M.1
-
29
-
-
65449146468
-
The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-γ production
-
Bourgeois E., et al. The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-γ production. Eur. J. Immunol. 2009, 39:1046-1055.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 1046-1055
-
-
Bourgeois, E.1
-
30
-
-
84857640602
-
+ T cell responses
-
+ T cell responses. Science 2012, 335:984-989.
-
(2012)
Science
, vol.335
, pp. 984-989
-
-
Bonilla, W.V.1
-
31
-
-
80054884522
-
+ T cells
-
+ T cells. Eur. J. Immunol. 2011, 41:3351-3360.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 3351-3360
-
-
Yang, Q.1
-
32
-
-
84926058212
-
T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses
-
Baumann C., et al. T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses. Proc. Natl. Acad. Sci. U.S.A. 2015, 112:4056-4061.
-
(2015)
Proc. Natl. Acad. Sci. U.S.A.
, vol.112
, pp. 4056-4061
-
-
Baumann, C.1
-
33
-
-
84906571227
-
The alarmin IL-33 promotes regulatory T-cell function in the intestine
-
Schiering C., et al. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature 2014, 513:564-568.
-
(2014)
Nature
, vol.513
, pp. 564-568
-
-
Schiering, C.1
-
34
-
-
67049158193
-
The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
-
Cayrol C., Girard J.P. The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:9021-9026.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 9021-9026
-
-
Cayrol, C.1
Girard, J.P.2
-
35
-
-
68249137289
-
Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
-
Luthi A.U., et al. Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 2009, 31:84-98.
-
(2009)
Immunity
, vol.31
, pp. 84-98
-
-
Luthi, A.U.1
-
36
-
-
84899419082
-
IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism
-
Kopach P., et al. IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism. J. Biol. Chem. 2014, 289:11829-11843.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 11829-11843
-
-
Kopach, P.1
-
37
-
-
84941686678
-
Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
-
Cohen E.S., et al. Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation. Nat. Commun. 2015, 6:8327.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8327
-
-
Cohen, E.S.1
-
38
-
-
79958086613
-
Interleukin-33 biology with potential insights into human diseases
-
Palmer G., Gabay C. Interleukin-33 biology with potential insights into human diseases. Nat. Rev. Rheumatol. 2011, 7:321-329.
-
(2011)
Nat. Rev. Rheumatol.
, vol.7
, pp. 321-329
-
-
Palmer, G.1
Gabay, C.2
-
39
-
-
0036772860
-
Activated, but not resting human Th2 cells, in contrast to Th1 and T regulatory cells, produce soluble ST2 and express low levels of ST2L at the cell surface
-
Lecart S., et al. Activated, but not resting human Th2 cells, in contrast to Th1 and T regulatory cells, produce soluble ST2 and express low levels of ST2L at the cell surface. Eur. J. Immunol. 2002, 32:2979-2987.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2979-2987
-
-
Lecart, S.1
-
40
-
-
84951566841
-
Activated mast cells synthesize and release soluble ST2 - a decoy receptor for IL-33
-
Bandara G., et al. Activated mast cells synthesize and release soluble ST2 - a decoy receptor for IL-33. Eur. J. Immunol. 2015, 45:3034-3044.
-
(2015)
Eur. J. Immunol.
, vol.45
, pp. 3034-3044
-
-
Bandara, G.1
-
41
-
-
1842293218
-
Role of interleukin 1 in the activation of T lymphocytes
-
Lichtman A.H., et al. Role of interleukin 1 in the activation of T lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 1988, 85:9699-9703.
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 9699-9703
-
-
Lichtman, A.H.1
-
42
-
-
0345546166
-
T helper cell subsets require the expression of distinct costimulatory signals by antigen-presenting cells
-
Weaver C.T., et al. T helper cell subsets require the expression of distinct costimulatory signals by antigen-presenting cells. Proc. Natl. Acad. Sci. U.S.A. 1988, 85:8181-8185.
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 8181-8185
-
-
Weaver, C.T.1
-
43
-
-
66349089266
-
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation
-
Ben-Sasson S.Z., et al. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:7119-7124.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 7119-7124
-
-
Ben-Sasson, S.Z.1
-
44
-
-
84877627620
-
IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells
-
Ben-Sasson S.Z., et al. IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells. J. Exp. Med. 2013, 210:491-502.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 491-502
-
-
Ben-Sasson, S.Z.1
-
45
-
-
84865081076
-
Interleukin-1R signaling is essential for induction of proapoptotic CD8 T cells, viral clearance, and pathology during lymphocytic choriomeningitis virus infection in mice
-
Joeckel L.T., et al. Interleukin-1R signaling is essential for induction of proapoptotic CD8 T cells, viral clearance, and pathology during lymphocytic choriomeningitis virus infection in mice. J. Virol. 2012, 86:8713-8719.
-
(2012)
J. Virol.
, vol.86
, pp. 8713-8719
-
-
Joeckel, L.T.1
-
46
-
-
84937557838
-
Interleukin-33 in tissue homeostasis, injury, and inflammation
-
Molofsky A.B., et al. Interleukin-33 in tissue homeostasis, injury, and inflammation. Immunity 2015, 42:1005-1019.
-
(2015)
Immunity
, vol.42
, pp. 1005-1019
-
-
Molofsky, A.B.1
-
47
-
-
69449106110
-
IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
-
Guo L., et al. IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:13463-13468.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 13463-13468
-
-
Guo, L.1
-
48
-
-
84896396519
-
The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells
-
Yagi R., et al. The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells. Immunity 2014, 40:378-388.
-
(2014)
Immunity
, vol.40
, pp. 378-388
-
-
Yagi, R.1
-
49
-
-
84955200559
-
Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment
-
Zhong C., et al. Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment. Nat. Immunol. 2016, 17:169-178.
-
(2016)
Nat. Immunol.
, vol.17
, pp. 169-178
-
-
Zhong, C.1
-
50
-
-
84880949850
-
+ Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation
-
+ Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. PLoS Biol. 2013, 11:e1001633.
-
(2013)
PLoS Biol.
, vol.11
, pp. e1001633
-
-
Peine, M.1
-
51
-
-
74549179138
-
+ cell subset with combined Th2 and Th1 cell functions
-
+ cell subset with combined Th2 and Th1 cell functions. Immunity 2010, 32:116-128.
-
(2010)
Immunity
, vol.32
, pp. 116-128
-
-
Hegazy, A.N.1
-
52
-
-
0033973582
-
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
-
Ouyang W., et al. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity 2000, 12:27-37.
-
(2000)
Immunity
, vol.12
, pp. 27-37
-
-
Ouyang, W.1
-
53
-
-
0037047149
-
GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model
-
Hofer T., et al. GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:9364-9368.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 9364-9368
-
-
Hofer, T.1
-
54
-
-
0035827347
-
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
-
Mullen A.C., et al. Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science 2001, 292:1907-1910.
-
(2001)
Science
, vol.292
, pp. 1907-1910
-
-
Mullen, A.C.1
-
55
-
-
84871783406
-
T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements
-
Kanhere A., et al. T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. Nat. Commun. 2012, 3:1268.
-
(2012)
Nat. Commun.
, vol.3
, pp. 1268
-
-
Kanhere, A.1
-
56
-
-
0035910037
-
T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells
-
Lighvani A.A., et al. T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:15137-15142.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 15137-15142
-
-
Lighvani, A.A.1
-
58
-
-
65549118531
-
Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-γ and interleukin-12
-
Schulz E.G., et al. Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-γ and interleukin-12. Immunity 2009, 30:673-683.
-
(2009)
Immunity
, vol.30
, pp. 673-683
-
-
Schulz, E.G.1
-
59
-
-
34547188748
-
H-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
H-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 2007, 8:967-974.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 967-974
-
-
Zhou, L.1
-
60
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva R., et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 2007, 448:480-483.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
-
61
-
-
0033427612
-
Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells
-
Kurata H., et al. Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells. Immunity 1999, 11:677688.
-
(1999)
Immunity
, vol.11
, pp. 677688
-
-
Kurata, H.1
-
62
-
-
78149322622
-
STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells
-
Onodera A., et al. STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells. J. Exp. Med. 2010, 207:2493-2506.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2493-2506
-
-
Onodera, A.1
-
63
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W., Flavell R.A. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997, 89:587-596.
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
64
-
-
0000344022
-
GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells
-
Lee H.J., et al. GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells. J. Exp. Med. 2000, 192:105-115.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 105-115
-
-
Lee, H.J.1
-
65
-
-
0034671565
-
Cutting edge: chromatin remodeling at the IL-4/IL-13 intergenic regulatory region for Th2-specific cytokine gene cluster
-
Takemoto N., et al. Cutting edge: chromatin remodeling at the IL-4/IL-13 intergenic regulatory region for Th2-specific cytokine gene cluster. J. Immunol. 2000, 165:6687-6691.
-
(2000)
J. Immunol.
, vol.165
, pp. 6687-6691
-
-
Takemoto, N.1
-
67
-
-
33846935457
-
Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3
-
Maneechotesuwan K., et al. Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3. J. Immunol. 2007, 178:2491-2498.
-
(2007)
J. Immunol.
, vol.178
, pp. 2491-2498
-
-
Maneechotesuwan, K.1
-
68
-
-
80051885764
-
Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types
-
Wei G., et al. Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity 2011, 35:299-311.
-
(2011)
Immunity
, vol.35
, pp. 299-311
-
-
Wei, G.1
-
69
-
-
84907569702
-
+ regulatory T cells
-
+ regulatory T cells. J. Immunol. 2014, 193:4010-4020.
-
(2014)
J. Immunol.
, vol.193
, pp. 4010-4020
-
-
Matta, B.M.1
-
70
-
-
84255178198
-
Early Th1 cell differentiation is marked by a Tfh cell-like transition
-
Nakayamada S., et al. Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity 2011, 35:919-931.
-
(2011)
Immunity
, vol.35
, pp. 919-931
-
-
Nakayamada, S.1
-
71
-
-
77953917067
-
Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
-
Wei L., et al. Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation. Immunity 2010, 32:840-851.
-
(2010)
Immunity
, vol.32
, pp. 840-851
-
-
Wei, L.1
-
72
-
-
0344806280
-
Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression
-
Richter A., et al. Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression. J. Exp. Med. 1999, 190:1439-1450.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1439-1450
-
-
Richter, A.1
-
73
-
-
0032143821
-
Helper T cell differentiation is controlled by the cell cycle
-
Bird J.J., et al. Helper T cell differentiation is controlled by the cell cycle. Immunity 1998, 9:229-237.
-
(1998)
Immunity
, vol.9
, pp. 229-237
-
-
Bird, J.J.1
-
74
-
-
0036305450
-
H cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
H cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat. Immunol. 2002, 3:643-651.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 643-651
-
-
Avni, O.1
-
75
-
-
58149214356
-
+ T cells
-
+ T cells. Immunity 2009, 30:155-167.
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
-
76
-
-
80555126115
-
+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival
-
+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival. J. Immunol. 2011, 187:4598-4610.
-
(2011)
J. Immunol.
, vol.187
, pp. 4598-4610
-
-
Turnquist, H.R.1
-
77
-
-
80052550470
-
Interleukin-33 prolongs allograft survival during chronic cardiac rejection
-
Brunner S.M., et al. Interleukin-33 prolongs allograft survival during chronic cardiac rejection. Transpl. Int. 2011, 24:1027-1039.
-
(2011)
Transpl. Int.
, vol.24
, pp. 1027-1039
-
-
Brunner, S.M.1
-
78
-
-
84931469546
-
IL-33 receptor ST2 amplifies the expansion of NK cells and enhances host defense during mouse cytomegalovirus infection
-
Nabekura T., et al. IL-33 receptor ST2 amplifies the expansion of NK cells and enhances host defense during mouse cytomegalovirus infection. J. Immunol. 2015, 194:5948-5952.
-
(2015)
J. Immunol.
, vol.194
, pp. 5948-5952
-
-
Nabekura, T.1
-
79
-
-
84904316116
-
IL-33/ST2 axis promotes mast cell survival via BCLXL
-
Wang J.X., et al. IL-33/ST2 axis promotes mast cell survival via BCLXL. Proc. Natl. Acad. Sci. U.S.A. 2014, 111:10281-10286.
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 10281-10286
-
-
Wang, J.X.1
-
80
-
-
84890235827
-
The interleukin-1 family: back to the future
-
Garlanda C., et al. The interleukin-1 family: back to the future. Immunity 2013, 39:1003-1018.
-
(2013)
Immunity
, vol.39
, pp. 1003-1018
-
-
Garlanda, C.1
-
81
-
-
75549091673
-
The IL-1 family: regulators of immunity
-
Sims J.E., Smith D.E. The IL-1 family: regulators of immunity. Nat. Rev. Immunol. 2010, 10:89-102.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 89-102
-
-
Sims, J.E.1
Smith, D.E.2
-
82
-
-
33846122035
-
+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation
-
+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation. Immunity 2006, 25:783-793.
-
(2006)
Immunity
, vol.25
, pp. 783-793
-
-
Gelman, A.E.1
-
83
-
-
33745304780
-
IL-18 bridges innate and adaptive immunity through IFN-γ and the CD134 pathway
-
Maxwell J.R., et al. IL-18 bridges innate and adaptive immunity through IFN-γ and the CD134 pathway. J. Immunol. 2006, 177:234-245.
-
(2006)
J. Immunol.
, vol.177
, pp. 234-245
-
-
Maxwell, J.R.1
-
84
-
-
34347371799
-
+ T cells from activation-induced cell death by IL-18
-
+ T cells from activation-induced cell death by IL-18. J. Leukoc. Biol. 2007, 82:142-151.
-
(2007)
J. Leukoc. Biol.
, vol.82
, pp. 142-151
-
-
Li, W.1
-
85
-
-
48749105319
-
+ T cell proliferation
-
+ T cell proliferation. PLoS ONE 2008, 3:e2404.
-
(2008)
PLoS ONE
, vol.3
, pp. e2404
-
-
Iwai, Y.1
-
86
-
-
56149110848
-
MyD88 plays a critical T cell-intrinsic role in supporting CD8 T cell expansion during acute lymphocytic choriomeningitis virus infection
-
Rahman A.H., et al. MyD88 plays a critical T cell-intrinsic role in supporting CD8 T cell expansion during acute lymphocytic choriomeningitis virus infection. J. Immunol. 2008, 181:3804-3810.
-
(2008)
J. Immunol.
, vol.181
, pp. 3804-3810
-
-
Rahman, A.H.1
-
87
-
-
84875463042
-
Molecular mechanisms of T cell co-stimulation and co-inhibition
-
Chen L., Flies D.B. Molecular mechanisms of T cell co-stimulation and co-inhibition. Nat. Rev. Immunol. 2013, 13:227-242.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 227-242
-
-
Chen, L.1
Flies, D.B.2
-
88
-
-
0142259712
-
Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
-
Rudd C.E., Schneider H. Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling. Nat. Rev. Immunol. 2003, 3:544-556.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 544-556
-
-
Rudd, C.E.1
Schneider, H.2
-
90
-
-
0028316562
-
Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells
-
Croft M., et al. Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. J. Immunol. 1994, 152:2675-2685.
-
(1994)
J. Immunol.
, vol.152
, pp. 2675-2685
-
-
Croft, M.1
-
91
-
-
0029800836
-
Memory alloreactive cytotoxic T cells do not require costimulation for activation in vitro
-
Flynn K., Mullbacher A. Memory alloreactive cytotoxic T cells do not require costimulation for activation in vitro. Immunol. Cell Biol. 1996, 74:413-420.
-
(1996)
Immunol. Cell Biol.
, vol.74
, pp. 413-420
-
-
Flynn, K.1
Mullbacher, A.2
-
92
-
-
0033577864
-
Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells
-
Bachmann M.F., et al. Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells. J. Exp. Med. 1999, 189:1521-1530.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1521-1530
-
-
Bachmann, M.F.1
-
93
-
-
38449119281
-
+ T cells require CD28 costimulation
-
+ T cells require CD28 costimulation. J. Immunol. 2007, 179:6494-6503.
-
(2007)
J. Immunol.
, vol.179
, pp. 6494-6503
-
-
Borowski, A.B.1
-
94
-
-
40449102228
-
+ T cell differentiation by CD80/CD86-CD28 costimulation and restoration by IL-2 during the recall response
-
+ T cell differentiation by CD80/CD86-CD28 costimulation and restoration by IL-2 during the recall response. J. Immunol. 2008, 180:1148-1157.
-
(2008)
J. Immunol.
, vol.180
, pp. 1148-1157
-
-
Fuse, S.1
-
95
-
-
33751571787
-
Control of memory CD4 T cell recall by the CD28/B7 costimulatory pathway
-
Ndejembi M.P., et al. Control of memory CD4 T cell recall by the CD28/B7 costimulatory pathway. J. Immunol. 2006, 177:7698-7706.
-
(2006)
J. Immunol.
, vol.177
, pp. 7698-7706
-
-
Ndejembi, M.P.1
-
96
-
-
79953122463
-
Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88
-
Rahman A.H., et al. Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88. Blood 2011, 117:3123-3130.
-
(2011)
Blood
, vol.117
, pp. 3123-3130
-
-
Rahman, A.H.1
-
97
-
-
84892474632
-
+ T cells is required to overcome suppression by regulatory T cells
-
+ T cells is required to overcome suppression by regulatory T cells. Immunity 2014, 40:78-90.
-
(2014)
Immunity
, vol.40
, pp. 78-90
-
-
Schenten, D.1
-
98
-
-
70049104738
-
IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38α-dependent pathway
-
Kroeger K.M., et al. IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38α-dependent pathway. J. Leukoc. Biol. 2009, 86:769-778.
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 769-778
-
-
Kroeger, K.M.1
-
99
-
-
37249049230
-
IL-33 induces IL-13 production by mouse mast cells independently of IgE-Fce[open]RI signals
-
Ho L.H., et al. IL-33 induces IL-13 production by mouse mast cells independently of IgE-Fce[open]RI signals. J. Leukoc. Biol. 2007, 82:1481-1490.
-
(2007)
J. Leukoc. Biol.
, vol.82
, pp. 1481-1490
-
-
Ho, L.H.1
-
100
-
-
0035284903
-
+ T cells: induction of type 2 cytokine production by T1/ST2 cross-linking
-
+ T cells: induction of type 2 cytokine production by T1/ST2 cross-linking. J. Immunol. 2001, 166:3143-3150.
-
(2001)
J. Immunol.
, vol.166
, pp. 3143-3150
-
-
Meisel, C.1
-
101
-
-
84941994329
-
Innate immunological function of TH2 cells in vivo
-
Guo L., et al. Innate immunological function of TH2 cells in vivo. Nat. Immunol. 2015, 16:1051-1059.
-
(2015)
Nat. Immunol.
, vol.16
, pp. 1051-1059
-
-
Guo, L.1
-
102
-
-
0030694235
-
IGIF does not drive Th1 development but synergizes with IL-12 for interferon-γ production and activates IRAK and NFκB
-
Robinson D., et al. IGIF does not drive Th1 development but synergizes with IL-12 for interferon-γ production and activates IRAK and NFκB. Immunity 1997, 7:571-581.
-
(1997)
Immunity
, vol.7
, pp. 571-581
-
-
Robinson, D.1
-
103
-
-
0033033469
-
+ T cells: evidence for two distinct pathways for promoter activation
-
+ T cells: evidence for two distinct pathways for promoter activation. Eur. J. Immunol. 1999, 29:548-555.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 548-555
-
-
Yang, J.1
-
104
-
-
0035863737
-
+ T cells contributes to the rapid production of IFN-γ in response to bacterial pathogens
-
+ T cells contributes to the rapid production of IFN-γ in response to bacterial pathogens. J. Immunol. 2001, 166:1097-1105.
-
(2001)
J. Immunol.
, vol.166
, pp. 1097-1105
-
-
Lertmemongkolchai, G.1
-
105
-
-
0036772485
-
+ T cells to innate immunity: IFN-γ secretion induced by IL-12 and IL-18
-
+ T cells to innate immunity: IFN-γ secretion induced by IL-12 and IL-18. Eur. J. Immunol. 2002, 32:2807-2816.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2807-2816
-
-
Berg, R.E.1
-
106
-
-
8044250881
-
Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
-
Szabo S.J., et al. Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 1997, 185:817-824.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 817-824
-
-
Szabo, S.J.1
-
107
-
-
0032212793
-
Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism
-
Ouyang W., et al. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity 1998, 9:745-755.
-
(1998)
Immunity
, vol.9
, pp. 745-755
-
-
Ouyang, W.1
-
108
-
-
78649539346
-
IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells
-
Lexberg M.H., et al. IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells. Eur. J. Immunol. 2010, 40:3017-3027.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 3017-3027
-
-
Lexberg, M.H.1
-
109
-
-
3643120790
-
Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells
-
Xu D., et al. Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. J. Exp. Med. 1998, 188:1485-1492.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1485-1492
-
-
Xu, D.1
-
110
-
-
39449101603
-
Transcriptional regulation of Th17 cell differentiation
-
Ivanov I.I., et al. Transcriptional regulation of Th17 cell differentiation. Semin. Immunol. 2007, 19:409-417.
-
(2007)
Semin. Immunol.
, vol.19
, pp. 409-417
-
-
Ivanov, I.I.1
-
111
-
-
33744921639
-
+ effector T cells
-
+ effector T cells. J. Immunol. 2006, 176:7278-7287.
-
(2006)
J. Immunol.
, vol.176
, pp. 7278-7287
-
-
O'Sullivan, B.J.1
-
112
-
-
77958128995
-
IL-1β-mediated signals preferentially drive conversion of regulatory T cells but not conventional T cells into IL-17-producing cells
-
Li L., et al. IL-1β-mediated signals preferentially drive conversion of regulatory T cells but not conventional T cells into IL-17-producing cells. J. Immunol. 2010, 185:4148-4153.
-
(2010)
J. Immunol.
, vol.185
, pp. 4148-4153
-
-
Li, L.1
-
113
-
-
84923437687
-
IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance
-
Basu R., et al. IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance. Nat. Immunol. 2015, 16:286-295.
-
(2015)
Nat. Immunol.
, vol.16
, pp. 286-295
-
-
Basu, R.1
-
114
-
-
84857885765
-
DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection
-
Oertli M., et al. DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection. J. Clin. Invest. 2012, 122:1082-1096.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1082-1096
-
-
Oertli, M.1
-
115
-
-
84939570120
-
+ Treg cell function in the intestine
-
+ Treg cell function in the intestine. Mucosal Immunol. 2015, 8:1226-1236.
-
(2015)
Mucosal Immunol.
, vol.8
, pp. 1226-1236
-
-
Harrison, O.J.1
-
116
-
-
36048978718
-
Host-derived interleukin-18 differentially impacts regulatory and conventional T cell expansion during acute graft-versus-host disease
-
Zeiser R., et al. Host-derived interleukin-18 differentially impacts regulatory and conventional T cell expansion during acute graft-versus-host disease. Biol. Blood Marrow Transplant. 2007, 13:1427-1438.
-
(2007)
Biol. Blood Marrow Transplant.
, vol.13
, pp. 1427-1438
-
-
Zeiser, R.1
-
117
-
-
53749106117
-
Distinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cells
-
Carroll R.G., et al. Distinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cells. PLoS ONE 2008, 3:e3289.
-
(2008)
PLoS ONE
, vol.3
, pp. e3289
-
-
Carroll, R.G.1
-
118
-
-
18844371714
-
+ regulatory T cell activity: it takes (IL-)two to tango
-
+ regulatory T cell activity: it takes (IL-)two to tango. Eur. J. Immunol. 2005, 35:1336-1341.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 1336-1341
-
-
Scheffold, A.1
-
120
-
-
84921292320
-
Individual T helper cells have a quantitative cytokine memory
-
Helmstetter C., et al. Individual T helper cells have a quantitative cytokine memory. Immunity 2015, 42:108-122.
-
(2015)
Immunity
, vol.42
, pp. 108-122
-
-
Helmstetter, C.1
|