메뉴 건너뛰기




Volumn 210, Issue 3, 2013, Pages 491-502

IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; OVALBUMIN;

EID: 84877627620     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20122006     Document Type: Article
Times cited : (199)

References (48)
  • 3
    • 84860237060 scopus 로고    scopus 로고
    • Regulation and function of mTOR signalling in T cell fate decisions
    • Chi, H. 2012. Regulation and function of mTOR signalling in T cell fate decisions. Nat. Rev. Immunol. 12:325-338.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 325-338
    • Chi, H.1
  • 5
    • 0033848939 scopus 로고    scopus 로고
    • Regulation of chemokine-induced transendothelial migration of T lymphocytes by endothelial activation: differential effects on naive and memory T cells
    • Ding, Z., K. Xiong, and T.B. Issekutz. 2000. Regulation of chemokine-induced transendothelial migration of T lymphocytes by endothelial activation: differential effects on naive and memory T cells. J. Leukoc. Biol. 67:825-833.
    • (2000) J. Leukoc. Biol. , vol.67 , pp. 825-833
    • Ding, Z.1    Xiong, K.2    Issekutz, T.B.3
  • 6
    • 0026068529 scopus 로고
    • Biological and immunological properties of human immunodeficiency virus type 1 envelope glycoprotein: analysis of proteins with truncations and deletions expressed by recombinant vaccinia viruses
    • Earl, P.L., S. Koenig, and B. Moss. 1991. Biological and immunological properties of human immunodeficiency virus type 1 envelope glycoprotein: analysis of proteins with truncations and deletions expressed by recombinant vaccinia viruses. J. Virol. 65:31-41.
    • (1991) J. Virol. , vol.65 , pp. 31-41
    • Earl, P.L.1    Koenig, S.2    Moss, B.3
  • 8
    • 0027320440 scopus 로고
    • Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16- transformed cells
    • Feltkamp, M.C., H.L. Smits, M.P. Vierboom, R.P. Minnaar, B.M. de Jongh, J.W. Drijfhout, J. ter Schegget, C.J. Melief, and W.M. Kast. 1993. Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16- transformed cells. Eur. J. Immunol. 23:2242-2249. http://dx.doi.org/10.1002/eji.1830230929
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2242-2249
    • Feltkamp, M.C.1    Smits, H.L.2    Vierboom, M.P.3    Minnaar, R.P.4    de Jongh, B.M.5    Drijfhout, J.W.6    ter Schegget, J.7    Melief, C.J.8    Kast, W.M.9
  • 9
    • 0025258534 scopus 로고
    • Independent regulation of IFN-gamma and tumor necrosis factor by IL-1 in human T helper cells
    • Fischer, H., G. Hedlund, T. Kalland, H.O. Sjögren, and M. Dohlsten. 1990. Independent regulation of IFN-gamma and tumor necrosis factor by IL-1 in human T helper cells. J. Immunol. 145:3767-3772.
    • (1990) J. Immunol. , vol.145 , pp. 3767-3772
    • Fischer, H.1    Hedlund, G.2    Kalland, T.3    Sjögren, H.O.4    Dohlsten, M.5
  • 10
    • 0030584838 scopus 로고    scopus 로고
    • Very late antigen-4/vascular cell adhesion molecule-1 (VLA-4/VCAM-1) pathway is involved in the transendothelial migration of lymphocytes in bancroftian filariasis
    • Freedman, D.O., S. Parker-Cook, M.C. Maia e Silva, C. Braga, and A. Maciel. 1996. Very late antigen-4/vascular cell adhesion molecule-1 (VLA-4/VCAM-1) pathway is involved in the transendothelial migration of lymphocytes in bancroftian filariasis. J. Immunol. 156:2901-2908.
    • (1996) J. Immunol. , vol.156 , pp. 2901-2908
    • Freedman, D.O.1    Parker-Cook, S.2    Maia e Silva, M.C.3    Braga, C.4    Maciel, A.5
  • 11
    • 34548704962 scopus 로고    scopus 로고
    • IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection
    • Fremond, C.M., D. Togbe, E. Doz, S. Rose, V. Vasseur, I. Maillet, M. Jacobs, B. Ryffel, and V.F. Quesniaux. 2007. IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection. J. Immunol. 179:1178-1189.
    • (2007) J. Immunol. , vol.179 , pp. 1178-1189
    • Fremond, C.M.1    Togbe, D.2    Doz, E.3    Rose, S.4    Vasseur, V.5    Maillet, I.6    Jacobs, M.7    Ryffel, B.8    Quesniaux, V.F.9
  • 13
    • 84861159419 scopus 로고    scopus 로고
    • TLR9 and MyD88 are crucial for the development of protective immunity to malaria
    • Gowda, N.M., X. Wu, and D.C. Gowda. 2012. TLR9 and MyD88 are crucial for the development of protective immunity to malaria. J. Immunol. 188:5073-5085. http://dx.doi.org/10.4049/jimmunol.1102143
    • (2012) J. Immunol. , vol.188 , pp. 5073-5085
    • Gowda, N.M.1    Wu, X.2    Gowda, D.C.3
  • 14
    • 74649086985 scopus 로고    scopus 로고
    • The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation
    • Gulen, M.F., Z. Kang, K. Bulek, W. Youzhong, T.W. Kim, Y. Chen, C.Z. Altuntas, K. Sass Bak-Jensen, M.J. McGeachy, J.S. Do, et al. 2010. The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity. 32:54-66. http://dx.doi.org/10.1016/j.immuni.2009.12.003
    • (2010) Immunity. , vol.32 , pp. 54-66
    • Gulen, M.F.1    Kang, Z.2    Bulek, K.3    Youzhong, W.4    Kim, T.W.5    Chen, Y.6    Altuntas, C.Z.7    Sass Bak-Jensen, K.8    McGeachy, M.J.9    Do, J.S.10
  • 15
    • 69449106110 scopus 로고    scopus 로고
    • IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
    • Guo, L., G. Wei, J. Zhu, W. Liao, W.J. Leonard, K. Zhao, and W. Paul. 2009. IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Proc. Natl. Acad. Sci. USA. 106:13463-13468. http://dx.doi.org/10.1073/pnas.0906988106
    • (2009) Proc. Natl. Acad. Sci. USA. , vol.106 , pp. 13463-13468
    • Guo, L.1    Wei, G.2    Zhu, J.3    Liao, W.4    Leonard, W.J.5    Zhao, K.6    Paul, W.7
  • 16
    • 0023614447 scopus 로고
    • Activation of resting, pure CD4+, and CD8+ cells via CD3 Requirements for second signals
    • Halvorsen, R., G. Gaudernack, T. Leivestad, F. Vartdal, and E. Thorsby. 1987. Activation of resting, pure CD4+, and CD8+ cells via CD3. Requirements for second signals. Scand. J. Immunol. 26:197-205. http://dx.doi.org/10.1111/j.1365-3083.1987.tb02252.x
    • (1987) Scand. J. Immunol. , vol.26 , pp. 197-205
    • Halvorsen, R.1    Gaudernack, G.2    Leivestad, T.3    Vartdal, F.4    Thorsby, E.5
  • 17
    • 0035117032 scopus 로고    scopus 로고
    • Differences in the induction of CD8+ T cell responses by subpopulations of dendritic cells from afferent lymph are related to IL-1 alpha secretion
    • Hope, J.C., P. Sopp, R.A. Collins, and C.J. Howard. 2001. Differences in the induction of CD8+ T cell responses by subpopulations of dendritic cells from afferent lymph are related to IL-1 alpha secretion. J. Leukoc. Biol. 69:271-279.
    • (2001) J. Leukoc. Biol. , vol.69 , pp. 271-279
    • Hope, J.C.1    Sopp, P.2    Collins, R.A.3    Howard, C.J.4
  • 18
    • 60549112774 scopus 로고    scopus 로고
    • Inflammasome recognition of influenza virus is essential for adaptive immune responses
    • Ichinohe, T., H.K. Lee, Y. Ogura, R. Flavell, and A. Iwasaki. 2009. Inflammasome recognition of influenza virus is essential for adaptive immune responses. J. Exp. Med. 206:79-87. http://dx.doi.org/10.1084/jem.20081667
    • (2009) J. Exp. Med. , vol.206 , pp. 79-87
    • Ichinohe, T.1    Lee, H.K.2    Ogura, Y.3    Flavell, R.4    Iwasaki, A.5
  • 19
    • 84865081076 scopus 로고    scopus 로고
    • Interleukin-1R signaling is essential for induction of proapoptotic CD8 T cells, viral clearance, and pathology during lymphocytic choriomeningitis virus infection in mice
    • Joeckel, L.T., R. Wallich, S.S. Metkar, C.J. Froelich, M.M. Simon, and C. Borner. 2012. Interleukin-1R signaling is essential for induction of proapoptotic CD8 T cells, viral clearance, and pathology during lymphocytic choriomeningitis virus infection in mice. J. Virol. 86:8713-8719. http://dx.doi.org/10.1128/JVI.00682-12
    • (2012) J. Virol. , vol.86 , pp. 8713-8719
    • Joeckel, L.T.1    Wallich, R.2    Metkar, S.S.3    Froelich, C.J.4    Simon, M.M.5    Borner, C.6
  • 20
    • 0028979828 scopus 로고
    • Interleukin 1 beta upregulates the expression of sulfoglucuronosyl paragloboside, a ligand for L-selectin, in brain microvascular endothelial cells
    • Kanda, T., M. Yamawaki, T. Ariga, and R.K. Yu. 1995. Interleukin 1 beta upregulates the expression of sulfoglucuronosyl paragloboside, a ligand for L-selectin, in brain microvascular endothelial cells. Proc. Natl. Acad. Sci. USA. 92:7897-7901. http://dx.doi.org/10.1073/pnas.92.17.7897
    • (1995) Proc. Natl. Acad. Sci. USA. , vol.92 , pp. 7897-7901
    • Kanda, T.1    Yamawaki, M.2    Ariga, T.3    Yu, R.K.4
  • 21
    • 0024598570 scopus 로고
    • Helper-independent CD8+ cytotoxic T lymphocytes express IL-1 receptors and require IL-1 for secretion of IL-2
    • Klarnet, J.P., D.E. Kern, S.K. Dower, L.A. Matis, M.A. Cheever, and P.D. Greenberg. 1989. Helper-independent CD8+ cytotoxic T lymphocytes express IL-1 receptors and require IL-1 for secretion of IL-2. J. Immunol. 142:2187-2191.
    • (1989) J. Immunol. , vol.142 , pp. 2187-2191
    • Klarnet, J.P.1    Kern, D.E.2    Dower, S.K.3    Matis, L.A.4    Cheever, M.A.5    Greenberg, P.D.6
  • 22
    • 77954939630 scopus 로고    scopus 로고
    • Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge
    • Kohlmeier, J.E., T. Cookenham, A.D. Roberts, S.C. Miller, and D.L. Woodland. 2010. Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge. Immunity. 33:96-105. http://dx.doi.org/10.1016/j.immuni.2010.06.016
    • (2010) Immunity. , vol.33 , pp. 96-105
    • Kohlmeier, J.E.1    Cookenham, T.2    Roberts, A.D.3    Miller, S.C.4    Woodland, D.L.5
  • 23
    • 77449112013 scopus 로고    scopus 로고
    • Regulating human Th17 cells via differential expression of IL-1 receptor
    • Lee, W.W., S.W. Kang, J. Choi, S.H. Lee, K. Shah, E.E. Eynon, R.A. Flavell, and I. Kang. 2010. Regulating human Th17 cells via differential expression of IL-1 receptor. Blood. 115:530-540. http://dx.doi.org/10.1182/blood-2009-08-236521
    • (2010) Blood. , vol.115 , pp. 530-540
    • Lee, W.W.1    Kang, S.W.2    Choi, J.3    Lee, S.H.4    Shah, K.5    Eynon, E.E.6    Flavell, R.A.7    Kang, I.8
  • 24
    • 43649107807 scopus 로고    scopus 로고
    • IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses
    • Lye, E., S. Dhanji, T. Calzascia, A.R. Elford, and P.S. Ohashi. 2008. IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses. Eur. J. Immunol. 38:870-876. http://dx.doi.org/10.1002/eji.200737429
    • (2008) Eur. J. Immunol. , vol.38 , pp. 870-876
    • Lye, E.1    Dhanji, S.2    Calzascia, T.3    Elford, A.R.4    Ohashi, P.S.5
  • 25
    • 38449085133 scopus 로고    scopus 로고
    • The lipopolysaccharide adjuvant effect on T cells relies on nonoverlapping contributions from the MyD88 pathway and CD11c+ cells
    • McAleer, J.P., D.J. Zammit, L. Lefrançois, R.J. Rossi, and A.T. Vella. 2007. The lipopolysaccharide adjuvant effect on T cells relies on nonoverlapping contributions from the MyD88 pathway and CD11c+ cells. J. Immunol. 179:6524-6535.
    • (2007) J. Immunol. , vol.179 , pp. 6524-6535
    • McAleer, J.P.1    Zammit, D.J.2    Lefrançois, L.3    Rossi, R.J.4    Vella, A.T.5
  • 26
    • 68949119874 scopus 로고    scopus 로고
    • IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis
    • McCandless, E.E., M. Budde, J.R. Lees, D. Dorsey, E. Lyng, and R.S. Klein. 2009. IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis. J. Immunol. 183:613- 620. http://dx.doi.org/10.4049/jimmunol.0802258
    • (2009) J. Immunol. , vol.183
    • McCandless, E.E.1    Budde, M.2    Lees, J.R.3    Dorsey, D.4    Lyng, E.5    Klein, R.S.6
  • 27
    • 0025262232 scopus 로고
    • Interleukin 1 inhibits T cell receptor-mediated apoptosis in immature thymocytes
    • McConkey, D.J., P. Hartzell, S.C. Chow, S. Orrenius, and M. Jondal. 1990. Interleukin 1 inhibits T cell receptor-mediated apoptosis in immature thymocytes. J. Biol. Chem. 265:3009-3011.
    • (1990) J. Biol. Chem. , vol.265 , pp. 3009-3011
    • McConkey, D.J.1    Hartzell, P.2    Chow, S.C.3    Orrenius, S.4    Jondal, M.5
  • 28
    • 0023807435 scopus 로고
    • IL-1 as a co-factor for lymphokine-secreting CD8+ murine T cells
    • Mizuochi, T., D.J. McKean, and A. Singer. 1988. IL-1 as a co-factor for lymphokine-secreting CD8+ murine T cells. J. Immunol. 141: 1571-1575.
    • (1988) J. Immunol. , vol.141 , pp. 1571-1575
    • Mizuochi, T.1    McKean, D.J.2    Singer, A.3
  • 29
    • 0031985770 scopus 로고    scopus 로고
    • Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesion
    • Mohamadzadeh, M., H. DeGrendele, H. Arizpe, P. Estess, and M. Siegelman. 1998. Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesion. J. Clin. Invest. 101:97-108. http://dx.doi.org/10.1172/JCI1604
    • (1998) J. Clin. Invest. , vol.101 , pp. 97-108
    • Mohamadzadeh, M.1    DeGrendele, H.2    Arizpe, H.3    Estess, P.4    Siegelman, M.5
  • 32
    • 79958086613 scopus 로고    scopus 로고
    • Interleukin-33 biology with potential insights into human diseases
    • Palmer, G., and C. Gabay. 2011. Interleukin-33 biology with potential insights into human diseases. Nat Rev Rheumatol. 7:321-329. http://dx.doi.org/10.1038/nrrheum.2011.53
    • (2011) Nat Rev Rheumatol. , vol.7 , pp. 321-329
    • Palmer, G.1    Gabay, C.2
  • 33
    • 0025188584 scopus 로고
    • Purified human T cells stimulated with cross-linked anti-CD3 monoclonal antibody OKT3: rIL-1 is a costimulatory factor for CD4+CD29+CD45RA- T cells
    • Panzer, S., R.L. Geller, and F.H. Bach. 1990. Purified human T cells stimulated with cross-linked anti-CD3 monoclonal antibody OKT3: rIL-1 is a costimulatory factor for CD4+CD29+CD45RA- T cells. Scand. J. Immunol. 32:359-371. http://dx.doi.org/10.1111/j.1365-3083.1990.tb02930.x
    • (1990) Scand. J. Immunol. , vol.32 , pp. 359-371
    • Panzer, S.1    Geller, R.L.2    Bach, F.H.3
  • 34
    • 0026624956 scopus 로고
    • Identification of subsets of human T cells capable of enhanced transendothelial migration
    • Pietschmann, P., J.J. Cush, P.E. Lipsky, and N. Oppenheimer-Marks. 1992. Identification of subsets of human T cells capable of enhanced transendothelial migration. J. Immunol. 149:1170-1178.
    • (1992) J. Immunol. , vol.149 , pp. 1170-1178
    • Pietschmann, P.1    Cush, J.J.2    Lipsky, P.E.3    Oppenheimer-Marks, N.4
  • 35
    • 53149135474 scopus 로고    scopus 로고
    • The adjuvanticity of a mannosylated antigen reveals TLR4 functionality essential for subset specialization and functional maturation of mouse dendritic cells
    • Sheng, K.C., M. Kalkanidis, D.S. Pouniotis, M.D. Wright, G.A. Pietersz, and V. Apostolopoulos. 2008. The adjuvanticity of a mannosylated antigen reveals TLR4 functionality essential for subset specialization and functional maturation of mouse dendritic cells. J. Immunol. 181:2455-2464.
    • (2008) J. Immunol. , vol.181 , pp. 2455-2464
    • Sheng, K.C.1    Kalkanidis, M.2    Pouniotis, D.S.3    Wright, M.D.4    Pietersz, G.A.5    Apostolopoulos, V.6
  • 36
    • 0027371220 scopus 로고
    • The Peyer's patch high endothelial receptor for lymphocytes, the mucosal vascular addressin, is induced on a murine endothelial cell line by tumor necrosis factor-alpha and IL-1
    • Sikorski, E.E., R. Hallmann, E.L. Berg, and E.C. Butcher. 1993. The Peyer's patch high endothelial receptor for lymphocytes, the mucosal vascular addressin, is induced on a murine endothelial cell line by tumor necrosis factor-alpha and IL-1. J. Immunol. 151:5239-5250.
    • (1993) J. Immunol. , vol.151 , pp. 5239-5250
    • Sikorski, E.E.1    Hallmann, R.2    Berg, E.L.3    Butcher, E.C.4
  • 37
    • 21444435368 scopus 로고    scopus 로고
    • Inactivation of the viral interleukin 1beta receptor improves CD8+ T-cell memory responses elicited upon immunization with modified vaccinia virus Ankara
    • Staib, C., S. Kisling, V. Erfle, and G. Sutter. 2005. Inactivation of the viral interleukin 1beta receptor improves CD8+ T-cell memory responses elicited upon immunization with modified vaccinia virus Ankara. J. Gen. Virol. 86:1997-2006. http://dx.doi.org/10.1099/vir.0.80646-0
    • (2005) J. Gen. Virol. , vol.86 , pp. 1997-2006
    • Staib, C.1    Kisling, S.2    Erfle, V.3    Sutter, G.4
  • 38
    • 0034654009 scopus 로고    scopus 로고
    • TNF-alpha, IL-4, and IFN-gamma regulate differential expression of P- and E-selectin expression by porcine aortic endothelial cells
    • Stocker, C.J., K.L. Sugars, O.A. Harari, R.C. Landis, B.J. Morley, and D.O. Haskard. 2000. TNF-alpha, IL-4, and IFN-gamma regulate differential expression of P- and E-selectin expression by porcine aortic endothelial cells. J. Immunol. 164:3309-3315.
    • (2000) J. Immunol. , vol.164 , pp. 3309-3315
    • Stocker, C.J.1    Sugars, K.L.2    Harari, O.A.3    Landis, R.C.4    Morley, B.J.5    Haskard, D.O.6
  • 39
    • 0023908364 scopus 로고
    • An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes
    • Takahashi, H., J. Cohen, A. Hosmalin, K.B. Cease, R. Houghten, J.L. Cornette, C. DeLisi, B. Moss, R.N. Germain, and J.A. Berzofsky. 1988. An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. USA. 85:3105-3109. http://dx.doi.org/10.1073/pnas.85.9.3105
    • (1988) Proc. Natl. Acad. Sci. USA. , vol.85 , pp. 3105-3109
    • Takahashi, H.1    Cohen, J.2    Hosmalin, A.3    Cease, K.B.4    Houghten, R.5    Cornette, J.L.6    DeLisi, C.7    Moss, B.8    Germain, R.N.9    Berzofsky, J.A.10
  • 41
    • 84857823725 scopus 로고    scopus 로고
    • Maximal adjuvant activity of nasally delivered IL-1? requires adjuvant-responsive CD11c(+) cells and does not correlate with adjuvant-induced in vivo cytokine production
    • Thompson, A.L., B.T. Johnson, G.D. Sempowski, M.D. Gunn, B. Hou, A.L. DeFranco, and H.F. Staats. 2012. Maximal adjuvant activity of nasally delivered IL-1? requires adjuvant-responsive CD11c(+) cells and does not correlate with adjuvant-induced in vivo cytokine production. J. Immunol. 188:2834-2846. http://dx.doi.org/10.4049/jimmunol.1100254
    • (2012) J. Immunol. , vol.188 , pp. 2834-2846
    • Thompson, A.L.1    Johnson, B.T.2    Sempowski, G.D.3    Gunn, M.D.4    Hou, B.5    DeFranco, A.L.6    Staats, H.F.7
  • 42
    • 79958730094 scopus 로고    scopus 로고
    • Inflammatory cytokines determine the susceptibility of human CD8 T cells to Fas-mediated activation-induced cell death through modulation of FasL and c-FLIP(S) expression
    • von Rossum, A., R. Krall, N.K. Escalante, and J.C. Choy. 2011. Inflammatory cytokines determine the susceptibility of human CD8 T cells to Fas-mediated activation-induced cell death through modulation of FasL and c-FLIP(S) expression. J. Biol. Chem. 286:21137-21144. http://dx.doi.org/10.1074/jbc.M110.197657
    • (2011) J. Biol. Chem. , vol.286 , pp. 21137-21144
    • von Rossum, A.1    Krall, R.2    Escalante, N.K.3    Choy, J.C.4
  • 43
    • 0027139704 scopus 로고
    • Lymphocyte adhesion to cultured endothelial cells of the blood-retinal barrier
    • Wang, Y.F., V.L. Calder, J. Greenwood, and S.L. Lightman. 1993. Lymphocyte adhesion to cultured endothelial cells of the blood-retinal barrier. J. Neuroimmunol. 48:161-168. http://dx.doi.org/10.1016/0165-5728(93)90188-5
    • (993) J. Neuroimmunol. , vol.48 , pp. 161-168
    • Wang, Y.F.1    Calder, V.L.2    Greenwood, J.3    Lightman, S.L.4
  • 44
    • 77952295021 scopus 로고    scopus 로고
    • Interleukin-1 (IL-1) pathway
    • Weber, A., P. Wasiliew, and M. Kracht. 2010. Interleukin-1 (IL-1) pathway. Sci. Signal. 3:cm1. http://dx.doi.org/10.1126/scisignal.3105cm1
    • (2010) Sci. Signal. , vol.3
    • Weber, A.1    Wasiliew, P.2    Kracht, M.3
  • 45
    • 2542434337 scopus 로고    scopus 로고
    • Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand
    • Wesa, A., and A. Galy. 2002. Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand. BMC Immunol. 3:14. http://dx.doi.org/10.1186/1471-2172-3-14
    • (2002) BMC Immunol. , vol.3 , pp. 14
    • Wesa, A.1    Galy, A.2
  • 47
    • 70449722457 scopus 로고    scopus 로고
    • The adaptor molecule MyD88 directly promotes CD8 T cell responses to vaccinia virus
    • Zhao, Y., C. De Trez, R. Flynn, C.F. Ware, M. Croft, and S. Salek-Ardakani. 2009. The adaptor molecule MyD88 directly promotes CD8 T cell responses to vaccinia virus. J. Immunol. 182:6278-6286. http://dx.doi.org/10.4049/jimmunol.0803682
    • (2009) J. Immunol. , vol.182 , pp. 6278-6286
    • Zhao, Y.1    De Trez, C.2    Flynn, R.3    Ware, C.F.4    Croft, M.5    Salek-Ardakani, S.6
  • 48
    • 76649093262 scopus 로고    scopus 로고
    • Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice
    • Zhu, Q., C. Egelston, S. Gagnon, Y. Sui, I.M. Belyakov, D.M. Klinman, and J.A. Berzofsky. 2010. Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice. J. Clin. Invest. 120:607-616. http://dx.doi.org/10.1172/JCI39293
    • (2010) J. Clin. Invest. , vol.120 , pp. 607-616
    • Zhu, Q.1    Egelston, C.2    Gagnon, S.3    Sui, Y.4    Belyakov, I.M.5    Klinman, D.M.6    Berzofsky, J.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.