Contribution of CD8+ T cells to innate immunity: IFN-γ secretion induced by IL-12 and IL-18

European Journal of Immunology

Volumn 32, Issue 10, 2002, Pages 2807-2816

  Berg, Rance E ^a   Cordes, Christoph J ^a   Forman, James ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Cell surface molecule; Cellular activation; Cytokine; T lymphocyte

Indexed keywords

BIOLOGICAL MARKER; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 18; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; BACTERIAL INFECTION; CELL ISOLATION; CELL LABELING; CELL PROLIFERATION; CELL SELECTION; CELL STRAIN; CELL SURFACE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DATA ANALYSIS; EXPERIMENTATION; IMMUNE RESPONSE; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; LISTERIA MONOCYTOGENES; LYMPHOCYTE CULTURE; LYMPHOCYTE FUNCTION; MACROPHAGE; MEMORY CELL; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; IMMUNITY, NATURAL; IMMUNOPHENOTYPING; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-18; LISTERIA MONOCYTOGENES; MICE;

EID: 0036772485     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(2002010)32:10<2807::AID-IMMU2807>3.0.CO;2-0     Document Type: Article

References (51)

1. Chang, J.T., Segal, B. M., Nakanishi, K., Okamura, H. and Shevach, E. M., The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit. Eur. J. Immunol. 2000. 30: 1113-1119.
2. Robinson, D., Shibuya, K., Mui, A., Zonin, F., Murphy, E., Sana, T., Hartley, S. B., Menon, S., Kastelein, R., Bazan, F. and O'Garra, A., IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB. Immunity 1997. 7: 571-581.
3. Yoshimoto, T., Takeda, K., Tanaka, T., Ohkusu, K., Kashiwamura, S., Okamura, H., Akira, S. and Nakanishi, K., IL-12 upregulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. J. Immunol. 1998. 161: 3400-3407.
4. Bancroft, G.J., The role of natural killer cells in innate resistance to infection. Curr. Opin. Immunol. 1993. 5: 503-510.
5. Bancroft, G. J., Schreiber, R. D., Bosma, G. C., Bosma, M. J. and Unanue, E. R., A T cell-independent mechanism of macrophage activation by interferon- gamma. J. Immunol. 1987. 139: 1104-1107.
6. Buchmeier, N. A. and Schreiber, R. D., Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection. Proc. Natl. Acad. Sci. USA 1985. 82: 7404-7408.
7. Harty, J. T. and Bevan, M. J., Specific immunity to Listeria monocytogenes in the absence of IFN gamma. Immunity 1995. 3: 109-117.
8. Ladel, C. H., Flesch, I. E., Arnoldi, J. and Kaufmann, S. H., Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection. J. Immunol. 1994. 153: 3116-3122.
9. Kaufmann, S. H. and Ladel, C. H., Role of T cell subsets in immunity against intracellular bacteria: experimental infections of knock-out mice with Listeria monocytogenes and Mycobacterium bovis BCG. Immunobiology 1994. 191: 509-519.
10. + T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha. J. Immunol. 1998. 160: 898-905.
11. Edelson, B. T. and Unanue, E. R., Immunity to Listeria infection. Curr. Opin. Immunol. 2000. 12: 425-431.
12. Shtrichman, R. and Samuel, C. E., The role of gamma interferon in antimicrobial immunity. Curr. Opin. Microbiol. 2001. 4: 251-259.
13. Dai, W. J., Bartens, W., Kohler, G., Hufnagel, M., Kopf, M. and Brombacher, F., Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN- gamma receptor-deficient mice. J. Immunol. 1997. 158: 5297-5304.
14. Yang, J., Zhu, H., Murphy, T. L., Ouyang, W. and Murphy, K. M., IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR- induced, IFN-gamma production. Nat. Immunol. 2001. 2: 157-164.
15. + T cells: evidence for two distinct pathways for promoter activation. Eur. J. Immunol. 1999. 29: 548-555.
16. + T lymphocytes in early IFN-gamma-dependent resistance to Toxoplasma gondii. J. Immunol. 1998. 160: 2565-2569.
17. Cao, X., Shores, E. W., Hu-Li, J., Anver, M. R., Kelsall, B. L., Russell, S. M., Drago, J., Noguchi, M., Grinberg, A. and Bloom, E. T., Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. Immunity 1995. 2: 223-238.
18. + lymphoid dendritic cells. J. Exp. Med. 1999. 189: 1981-1986.
19. Stober, D., Schirmbeck, R. and Reimann, J., Il-12/il-18-dependent IFN-gamma release by murine dendritic cells. J. Immunol. 2001. 167: 957-965.
20. Puddu, P., Fantuzzi, L., Borghi, P., Varano, B., Rainaldi, G., Guillemard, E., Malorni, W., Nicaise, R, Wolf, S. F., Belardelli, F. and Gessani, S., IL-12 induces IFN-gamma expression and secretion in mouse peritoneal macrophages. J. Immunol. 1997. 159: 3490-3497.
21. Munder, M., Mallo, M., Eichmann, K. and Modolell, M., Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation. J. Exp. Med. 1998. 187: 2103-2108.
22. Andersson, A., Dai, W. J., Di Santo, J. P. and Brombacher, F., Early IFN-gamma production and innate immunity during Listeria monocytogenes infection in the absence of NK cells. J. Immunol. 1998. 161: 5600-5606.
23. Bregenholt, S., Berche, P., Brombacher, F. and Di Santo, J.P., Conventional alpha beta T cells are sufficient for innate and adaptive immunity against enteric Listeria monocytogenes. J. Immunol. 2001. 166: 1871-1876.
24. + T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens. J. Immunol. 2001. 166: 1097-1105.
25. Seaman, M. S., Perarnau, B., Lindahl, K. F., Lemonnier, F. A. and Forman, J., Response to Listeria monocytogenes in mice lacking MHC class la molecules. J Immunol. 1999. 162: 5429-5436.
26. Kerksiek, K. M., Busch, D. H., Pilip, I. M., Allen, S. E. and Pamer, E. G., H2-M3-restricted T cells in bacterial infection: rapid primary but diminished memory responses. J. Exp. Med. 1999. 190: 1195-204.
27. Tripp, C. S., Gately, M. K., Hakimi, J., Ling, P. and Unanue, E. R., Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma. J. Immunol. 1994. 152: 1883-1887.
28. Tripp, C. S., Wolf, S. F. and Unanue, E. R., Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc. Natl. Acad. Sci. USA 1993. 90: 3725-3729.
29. Thornton, S., Kuhn, K. A., Finkelman, F. D. and Hirsch, R., NK cells secrete high levels of IFN-gamma in response to in vivo administration of IL-2. Eur. J. Immunol. 2001. 31: 3355-3360.
30. Nakanishi, K., Yoshimoto, T., Tsutsui, H. and Okamura, H., Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Cytokine Growth Factor Rev. 2001. 12: 53-72.
31. Cerwenka, A., Carter, L. L., Reome, J. B., Swain, S. L. and Dutton, R. W., In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines. J. Immunol. 1998. 161: 97-105.
32. + T cells are hyperreactive to antigenic challenge in vitro. J. Exp. Med. 1996. 184: 2141-2151.
33. Desai, B. B., Quinn, P. M., Wolitzky, A. G., Mongini, P.K., Chizzonite, R. and Gately, M. K., IL-12 receptor. II. Distribution and regulation of receptor expression. J. Immunol. 1992. 148: 3125-3132.
34. Gollob, J. A., Schnipper, C. P., Orsini, E., Murphy, E., Daley, J. F., Lazo, S. B., Frank, D. A., Neuberg, D. and Ritz, J., Characterization of a novel subset of CD8(+) T cells that expands in patients receiving interleukin-12. J. Clin. Invest 1998. 102: 561-575.
35. Chan, W. L., Pejnovic, N., Lee, C. A. and Al Ali, N. A., Human IL-18 receptor and st2 I are stable and selective markers for the respective type 1 and type 2 circulating lymphocytes. J. Immunol. 2001. 167: 1238-1244.
36. Xu, D., Chan, W. L., Leung, B. P., Hunter, D., Schulz, K., Carter, R. W., McInnes, I. B., Robinson, J. H. and Liew, F. Y., Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. J. Exp. Med. 1998. 188: 1485-1492.
37. + memory T cells by opposing cytokines. Science 2000. 288: 675-678.
38. Ganapamo, F., Dennis, V. A. and Philipp, M. T., CD19(+) cells produce IFN-gamma in mice infected with Borrelia burgdorferi. Eur. J. Immunol. 2001. 31: 3460-3468.
39. Jacobson, N. G., Szabo, S. J., Guler, M. L., Gorham, J. D. and Murphy, K. M., Regulation of interleukin-12 signalling during T helper phenotype development. Adv. Exp. Med. Biol. 1996. 409: 61-73.
40. Guler, M. L., Jacobson, N. G., Gubler, U. and Murphy, K. M., T cell genetic background determines maintenance of IL-12 signaling: effects on BALB/c and B10.D2 T helper cell type 1 phenotype development. J. Immunol. 1997. 159: 1767-1774.
41. Hodge, D. L., Martinez, A., Julias, J. G., Taylor, L. S. and Young, H. A., Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control. Mol. Cell Biol. 2002. 22: 1742-1753.
42. + T cells in vivo by IL-15. Immunity 1998. 8: 591-599.
43. Yajima, T., Nishimura, H., Ishimitsu, R., Yamamura, K., Watase, T., Busch, D. H., Pamer, E. G. Kuwano, H. and Yoshikai, Y., Memory phenotype CD8(+) T cells in IL-15 transgenic mice are involved in early protection against a primary infection with Listeria monocytogenes. Eur. J. Immunol. 2001. 31: 757-766.
44. Hochrein, H., Shortman, K., Vremec, D., Scott, B., Hertzog, P. and O'Keeffe, M., Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets. J. Immunol. 2001. 166: 5448-5455.
45. Cho, B. K., Wang, C., Sugawa, S., Eisen, H. N. and Chen, J., Functional differences between memory and naive CD8 T cells. Proc. Natl. Acad. Sci. USA 1999. 96: 2976-2981.
46. Sallusto, F., Lenig, D., Forster, R., Lipp, M. and Lanzavecchia, A., Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999. 401: 708-712.
47. Weninger, W., Crowley, M. A., Manjunath, N. and von Andrian, U. H., Migratory properties of naive, effector, and memory CD8(+) T cells. J. Exp. Med. 2001. 194: 953-966.
48. + T cell turnover in vivo by IL-12, IL-18, and IFN-gamma. J. Immunol. 2001. 166: 6007-6011.
49. Berg, R. E., Princiotta, M. F., Irion, S., Moticka, J. A., Dahl, K. R., and Staerz, U. D., Positive selection of an H2-M3 restricted T cell receptor. Immunity 1999. 11: 33-43.
50. Hogquist, K. A., Jameson, S. C., Heath, W. R., Howard, J. L., Bevan, M. J. and Carbone, F. R., T cell receptor antagonist peptides induce positive selection. Cell 1994. 76: 17-27.
51. Seaman, M. S., Wang, C. R. and Forman, J., MHC class Ib-restricted CTL provide protection against primary and secondary Listeria monocytogenes infection. J. Immunol. 2000. 165: 5192-5201.