AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 38, 2011, Pages 16092-16097

  O'Neill, Hayley M ^a,b   Maarbjerg, Stine J ^c   Crane, Justin D ^a   Jeppesen, Jacob ^c   Jørgensen, Sebastian B ^d   Schertzer, Jonathan D ^a   Shyroka, Olga ^a   Kiens, Bente ^c   Van Denderen, Bryce J ^b   Tarnopolsky, Mark A ^a   Kemp, Bruce E ^b   Richter, Erik A ^c   Steinberg, Gregory R ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d NOVO NORDISK A S   (Denmark)

Author keywords

AS160; Obesity; PGC1 ; TBC1D1; Type 2 diabetes

Indexed keywords

AMP ACTIVATED PROTEIN KINASE BETA1; AMP ACTIVATED PROTEIN KINASE BETA1BETA2; AMP ACTIVATED PROTEIN KINASE BETA2; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME SUBUNIT; GENE DELETION; GLUCOSE INTAKE; GLUCOSE TRANSPORT; INSULIN SENSITIVITY; KNOCKOUT MOUSE; MALE; MITOCHONDRIAL CONTENT; MOUSE; MUSCLE CONTRACTION; MUSCLE MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; TREADMILL EXERCISE; UPREGULATION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DNA, MITOCHONDRIAL; FEMALE; GLUCOSE; HYPOGLYCEMIC AGENTS; IMMUNOBLOTTING; INSULIN; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; MUSCLE CONTRACTION; MUSCLE, SKELETAL; PHYSICAL CONDITIONING, ANIMAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MUS;

EID: 80053163909     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105062108     Document Type: Article

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