Vitamin C facilitates demethylation of the Foxp3 Enhancer in a Tet-Dependent Manner

Journal of Immunology

Volumn 196, Issue 5, 2016, Pages 2119-2131

  Nair, Varun Sasidharan ^a   Song, Mi Hye ^a   Oh, Kwon Ik ^a  

^a Hallym University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; ASCORBIC ACID; CELL PROTEIN; METHYL GROUP; SODIUM; SULFINPYRAZONE; TEN ELEVEN TRANSLOCATION 2 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; TET DNA POLYMERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MATURATION; CONSERVED NONCODING SEQUENCE 2 DEMETHYLATION; CONTROLLED STUDY; DEMETHYLATION; ENHANCER REGION; EPIGENETICS; FOXP3 GENE; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; REGULATORY T LYMPHOCYTE; TET2 GENE; THYMOCYTE; ADOPTIVE TRANSFER; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL SEPARATION; CPG ISLAND; DNA METHYLATION; DNA MICROARRAY; DRUG EFFECTS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; IMMUNOPRECIPITATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; ASCORBIC ACID; CELL SEPARATION; CPG ISLANDS; DNA METHYLATION; DNA-DIRECTED DNA POLYMERASE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES, REGULATORY; TRANSFECTION;

EID: 84962016102     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1502352     Document Type: Article

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