Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis

Immunity

Volumn 43, Issue 2, 2015, Pages 251-263

  Yang, Ruili ^a,b,c   Qu, Cunye ^c   Zhou, Yu ^d   Konkel, Joanne E ^e   Shi, Shihong ^c   Liu, Yi ^f   Chen, Chider ^b,c   Liu, Shiyu ^c   Liu, Dawei ^a   Chen, Yibu ^d   Zandi, Ebrahim ^d   Chen, Wanjun ^e   Zhou, Yanheng ^a   Shi, Songtao ^b,c  

^a PEKING UNIVERSITY SCHOOL AND HOSPITAL OF STOMATOLOGY   (China)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^f CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; DIOXYGENASE; HYDROGEN SULFIDE; INTERLEUKIN 2; METHYLCYTOSINE DIOXYGENASE TET1; METHYLCYTOSINE DIOXYGENASE TET2; SMAD3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CCAAT BINDING FACTOR; DNA BINDING PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; NFYB PROTEIN, MOUSE; ONCOPROTEIN; STAT5 PROTEIN; TET1 PROTEIN, MOUSE; TET2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DNA METHYLATION; HOMEOSTASIS; IMMUNOCOMPETENT CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; ADOPTIVE TRANSFER; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; COLITIS; GENETICS; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; TRANSPLANTATION;

ADOPTIVE TRANSFER; ANIMALS; CCAAT-BINDING FACTOR; CELL DIFFERENTIATION; COLITIS; DNA METHYLATION; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; HOMEOSTASIS; HUMANS; HYDROGEN SULFIDE; INTERLEUKIN-2; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS; SMAD3 PROTEIN; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA;

EID: 84940971884     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2015.07.017     Document Type: Article

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