메뉴 건너뛰기




Volumn 20, Issue 5, 2015, Pages 699-716

How taste works: Cells, receptors and gustatory perception

Author keywords

Activation of taste receptor cells; Basic taste qualities; Bitter; Calcium homeostasis modulator 1 channel; CALHM1; ENaC; Epithelial sodium channels; Extra oral tissue TAS2Rs; Sweet and umami taste receptors; TASRs; Taste buds; Taste papillae; Taste perception; Types of cells located in the taste buds

Indexed keywords

G PROTEIN COUPLED RECEPTOR; SODIUM CHANNEL; TASTE RECEPTORS, TYPE 1; TASTE RECEPTORS, TYPE 2;

EID: 84961244099     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.1515/cmble-2015-0042     Document Type: Article
Times cited : (45)

References (89)
  • 1
    • 84940250250 scopus 로고    scopus 로고
    • Prediction of the bitter taste of chromones and furochromones using Simple Pharmacophore Model (SPM)
    • Kikut-Ligaj, D. Prediction of the bitter taste of chromones and furochromones using Simple Pharmacophore Model (SPM). Food Science Technology Quality 1 (2014) 200-214.
    • (2014) Food Science Technology Quality , vol.1 , pp. 200-214
    • Kikut-Ligaj, D.1
  • 3
    • 84875422553 scopus 로고    scopus 로고
    • Biosensor recording of extracellular potentials in the taste epithelium for bitter detection
    • Liu, Q., Zhang, D., Zhang, F., Zhao, Y., Hsia, K.J. and Wang, P. Biosensor recording of extracellular potentials in the taste epithelium for bitter detection. Sens. Actuators B Chem. 176 (2013) 497-504.
    • (2013) Sens. Actuators B Chem. , vol.176 , pp. 497-504
    • Liu, Q.1    Zhang, D.2    Zhang, F.3    Zhao, Y.4    Hsia, K.J.5    Wang, P.6
  • 4
    • 68649105402 scopus 로고    scopus 로고
    • Taste, smell and chemesthesis in product experience
    • (Schifferstein, H.N.I. and Hekkert, P. Eds.)
    • Cardello, A.V. and Wise, P.M. Taste, smell and chemesthesis in product experience. in: Prod. Experience (Schifferstein, H.N.I. and Hekkert, P. Eds.), 2008, 91-131.
    • (2008) Prod Experience , pp. 91-131
    • Cardello, A.V.1    Wise, P.M.2
  • 6
    • 84868475929 scopus 로고    scopus 로고
    • Sensory perception and understanding of food uniqueness: From the traditional to the novel
    • Favalli, S., Skov, T. and Byrne, D.V. Sensory perception and understanding of food uniqueness: From the traditional to the novel. Food Res. Int. 50 (2013) 176-188.
    • (2013) Food Res. Int. , vol.50 , pp. 176-188
    • Favalli, S.1    Skov, T.2    Byrne, D.V.3
  • 7
    • 84961272711 scopus 로고    scopus 로고
    • Quality management. Fundamental problems and methods
    • in Polish
    • Iwasiewicz, A. [Quality management. Fundamental problems and methods.] PWN, Warsaw, Poland, 1999, in Polish.
    • (1999) PWN, Warsaw, Poland
    • Iwasiewicz, A.1
  • 8
    • 0035287498 scopus 로고    scopus 로고
    • Making sense of taste
    • Smith, D.V. and Margolskee, R.F. Making sense of taste. Sci. Am. 284 (2001) 32-39.
    • (2001) Sci. Am. , vol.284 , pp. 32-39
    • Smith, D.V.1    Margolskee, R.F.2
  • 9
    • 80052501471 scopus 로고    scopus 로고
    • A gustotopic map of taste qualities in the mammalian
    • Chen, X., Gabitto, M., Peng, Y., Ryba, N.J. and Zuker, C.S. A gustotopic map of taste qualities in the mammalian. Brain Sci. 333 (2011) 1262-1266.
    • (2011) Brain Sci. , vol.333 , pp. 1262-1266
    • Chen, X.1    Gabitto, M.2    Peng, Y.3    Ryba, N.J.4    Zuker, C.S.5
  • 10
    • 0345016453 scopus 로고    scopus 로고
    • Lingual tactile acuity, taste perception, and the density and diameter of fungiform papillae in female subjects
    • Essick, G.K., Chopra, A., Guest, S. and McGlone, F. Lingual tactile acuity, taste perception, and the density and diameter of fungiform papillae in female subjects. Physiol. Behav. 80 (2003) 289-302.
    • (2003) Physiol. Behav. , vol.80 , pp. 289-302
    • Essick, G.K.1    Chopra, A.2    Guest, S.3    McGlone, F.4
  • 11
    • 84862552290 scopus 로고    scopus 로고
    • Gustatory system: The finer points of taste
    • Trivedi, B.P. Gustatory system: the finer points of taste. Nature 486 (2012) S2-3. DOI:10.1038/486S2a.
    • (2012) Nature , vol.486 , pp. S2-3
    • Trivedi, B.P.1
  • 12
    • 70349984438 scopus 로고    scopus 로고
    • Common sense about taste: From mammals to insects
    • Yarmolinsky, D.A., Zuker, C.S. and Ryba, N.J. Common sense about taste: from mammals to insects. Cell 139 (2009) 234-244.
    • (2009) Cell , vol.139 , pp. 234-244
    • Yarmolinsky, D.A.1    Zuker, C.S.2    Ryba, N.J.3
  • 13
    • 84873431549 scopus 로고    scopus 로고
    • Taste buds as peripheral chemosensory processors
    • Roper, S.D. Taste buds as peripheral chemosensory processors. Semin. Cell Dev. Biol. 24 (2013) 71-79.
    • (2013) Semin. Cell Dev. Biol. , vol.24 , pp. 71-79
    • Roper, S.D.1
  • 14
    • 0023373243 scopus 로고
    • Three-dimensional structures of the connective tissue papillae of the tongue in the newborn dogs
    • Kobayashi, K., Miyata, K. and Iino, T. Three-dimensional structures of the connective tissue papillae of the tongue in the newborn dogs. Arch. Histol. Jpn. 50 (1987) 347-357.
    • (1987) Arch. Histol. Jpn. , vol.50 , pp. 347-357
    • Kobayashi, K.1    Miyata, K.2    Iino, T.3
  • 15
    • 1942422668 scopus 로고    scopus 로고
    • The scanning electron microscopic study of lingual papillae in the silver fox (Vulpes vulpes fulva, Desmarest 1820)
    • Jackowiak, H. and Godynicki, S. The scanning electron microscopic study of lingual papillae in the silver fox (Vulpes vulpes fulva, Desmarest, 1820). Ann. Anat. 186 (2004) 179-183.
    • (2004) Ann. Anat. , vol.186 , pp. 179-183
    • Jackowiak, H.1    Godynicki, S.2
  • 16
    • 12344302580 scopus 로고    scopus 로고
    • Veterinary anatomy of domestic mammals
    • Ed. Schattauer, Stuttgart, New York
    • König, H.E. and Liebich, H.G. Veterinary Anatomy of Domestic Mammals. Textbook and Colour Atlas. 3. Ed. Schattauer, Stuttgart, New York, 2006.
    • (2006) Textbook and Colour Atlas. , vol.3
    • König, H.E.1    Liebich, H.G.2
  • 18
    • 0001278041 scopus 로고
    • Comparative anatomical and neurohistological observations on the tongue of the marsupials
    • Kubota, K., Kubota, J., Fukuda, N., Asakura, S., Nakagawa, S. and Masui, M. Comparative anatomical and neurohistological observations on the tongue of the marsupials. Anat. Rec. 147 (1963) 337-353.
    • (1963) Anat. Rec. , vol.147 , pp. 337-353
    • Kubota, K.1    Kubota, J.2    Fukuda, N.3    Asakura, S.4    Nakagawa, S.5    Masui, M.6
  • 20
    • 0021828902 scopus 로고
    • Scanning electron microscopy of the lingual dorsal surface of the beagle dog
    • Iwasaki, S. and Sakata, K. Scanning electron microscopy of the lingual dorsal surface of the beagle dog. Okajimas Folia Anat. Jpn. 62 (1985) 1-14.
    • (1985) Okajimas Folia Anat. Jpn. , vol.62 , pp. 1-14
    • Iwasaki, S.1    Sakata, K.2
  • 21
    • 84939662465 scopus 로고
    • Comparative scanning electron-microscopic study of the lingual papillae in two species of domestic mammals (Equus caballus and Bos taurus). I. Gustatory papillae
    • Chamorro, C.A., de Paz, P., Snadval, J. and Fernandez, J.G. Comparative scanning electron-microscopic study of the lingual papillae in two species of domestic mammals (Equus caballus and Bos taurus). I. Gustatory papillae. Acta Anat. 125 (1986) 83-87.
    • (1986) Acta Anat , vol.125 , pp. 83-87
    • Chamorro, C.A.1    De Paz, P.2    Snadval, J.3    Fernandez, J.G.4
  • 22
    • 7744220481 scopus 로고    scopus 로고
    • SEM and gross study on the lingual surface of the lion Panthera leo
    • Emura, S., Hayakawa, D., Chen, H. and Shoumura, S. SEM and gross study on the lingual surface of the lion, Panthera leo. Mamm. Sci. 43 (2003) 45-50.
    • (2003) Mamm. Sci. , vol.43 , pp. 45-50
    • Emura, S.1    Hayakawa, D.2    Chen, H.3    Shoumura, S.4
  • 23
    • 3042528547 scopus 로고    scopus 로고
    • Spacing patterns on tongue surfacegustatory papilla
    • Jung, H.S., Akita, K. and Kim, J.Y. Spacing patterns on tongue surfacegustatory papilla. Int. J. Dev. Biol. 48 (2004) 157-161.
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 157-161
    • Jung, H.S.1    Akita, K.2    Kim, J.Y.3
  • 25
    • 0037423367 scopus 로고    scopus 로고
    • Coding of sweet, bitter, and umami tastes: Different receptor cells sharing similar signaling pathways
    • Zhang, Y., Hoon, M.A., Chandrashekar, J., Mueller, K.L., Cook, B. and Wu, D. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Cell 112 (2003) 293-301.
    • (2003) Cell , vol.112 , pp. 293-301
    • Zhang, Y.1    Hoon, M.A.2    Chandrashekar, J.3    Mueller, K.L.4    Cook, B.5    Wu, D.6
  • 27
    • 0001227601 scopus 로고
    • Sweetness: History, preference and genetic variability
    • Bartoshuk, L.M. Sweetness: history, preference and genetic variability. Food Technol. 45 (1991) 108-113.
    • (1991) Food Technol. , vol.45 , pp. 108-113
    • Bartoshuk, L.M.1
  • 29
    • 0002376528 scopus 로고
    • Number and distribution of taste buds on the epiglottis, pharynx, larynx, soft palate and uvula in a human newborn
    • Lalonde, E.R. and Eglitis, J.A. Number and distribution of taste buds on the epiglottis, pharynx, larynx, soft palate and uvula in a human newborn. Anat. Rec. 140 (1961) 91-95.
    • (1961) Anat. Rec. , vol.140 , pp. 91-95
    • Lalonde, E.R.1    Eglitis, J.A.2
  • 30
    • 0022968097 scopus 로고
    • Variation in human fungiform taste bud densities among regions and subjects
    • Miller, Jr I.J. Variation in human fungiform taste bud densities among regions and subjects. Anat. Rec. 216 (1986) 474-482.
    • (1986) Anat. Rec. , vol.216 , pp. 474-482
    • Miller, I.J.1
  • 31
    • 0002673542 scopus 로고
    • Anatomy of the peripheral taste system
    • ( Doty, R.L. Eds.) Dekker, New York, U.S.A.
    • Miller, Jr I.J. Anatomy of the peripheral taste system. in: Handbook of olfaction and gustation. (Doty, R.L. Eds.) Dekker, New York, U.S.A. 1995, 521-547.
    • (1995) Handbook of Olfaction and Gustation , pp. 521-547
    • Miller, I.J.1
  • 32
    • 0027431715 scopus 로고
    • Cellular relations in mouse circumvallate taste buds
    • Murray, R.G. Cellular relations in mouse circumvallate taste buds. Microsc. Res. Tech. 26 (1993) 209-224.
    • (1993) Microsc. Res. Tech. , vol.26 , pp. 209-224
    • Murray, R.G.1
  • 33
    • 0022977463 scopus 로고
    • Ultrastructure of mouse vallate taste buds: II. Cell types and cell lineage
    • Delay, R.J., Kinnamon, J.C. and Roper, S.D. Ultrastructure of mouse vallate taste buds: II. Cell types and cell lineage. J. Comp. Neurol. 253 (1986) 242-252.
    • (1986) J. Comp. Neurol. , vol.253 , pp. 242-252
    • Delay, R.J.1    Kinnamon, J.C.2    Roper, S.D.3
  • 34
    • 0027495899 scopus 로고
    • Immunolocalization of different forms of neural cell adhesion molecule (NCAM) in rat taste buds
    • Nelson, G.M. and Finger, T.E. Immunolocalization of different forms of neural cell adhesion molecule (NCAM) in rat taste buds. J. Comp. Neurol. 336 (1993) 507-516.
    • (1993) J. Comp. Neurol. , vol.336 , pp. 507-516
    • Nelson, G.M.1    Finger, T.E.2
  • 35
    • 0031038610 scopus 로고    scopus 로고
    • Light and dark cells of rat vallate taste buds are morphologically distinct cell types
    • Pumplin, D.W., Yu, C. and Smith, D.V. Light and dark cells of rat vallate taste buds are morphologically distinct cell types. J. Comp. Neurol. 378 (1997) 389-410.
    • (1997) J. Comp. Neurol. , vol.378 , pp. 389-410
    • Pumplin, D.W.1    Yu, C.2    Smith, D.V.3
  • 36
    • 84872185179 scopus 로고    scopus 로고
    • Functional cell types in taste buds have distinct longevities
    • Perea-Martinez, I., Nagai, T. and Chaudhari, N. Functional cell types in taste buds have distinct longevities. PLoS One 8 (2013) e53399. DOI:10.1371/journal.pone. 0053399.
    • (2013) PLoS One , vol.8 , pp. e53399
    • Perea-Martinez, I.1    Nagai, T.2    Chaudhari, N.3
  • 37
    • 0348010256 scopus 로고    scopus 로고
    • Morphologic characterization of rat taste receptor cells that express components of the phospholipase C signaling pathway
    • Clapp, T.R., Yang, R., Stoick, C.L., Kinnamon, S.C. and Kinnamon, J.C. Morphologic characterization of rat taste receptor cells that express components of the phospholipase C signaling pathway. J. Comp. Neurol. 468 (2004) 311-321.
    • (2004) J. Comp. Neurol. , vol.468 , pp. 311-321
    • Clapp, T.R.1    Yang, R.2    Stoick, C.L.3    Kinnamon, S.C.4    Kinnamon, J.C.5
  • 39
    • 45249103556 scopus 로고    scopus 로고
    • Presynaptic (Type III) cells in mouse taste buds sense sour (acid) taste
    • Huang, Y.A., Maruyama, Y., Stimac, R. and Roper, S.D. Presynaptic (Type III) cells in mouse taste buds sense sour (acid) taste. J. Physiol. 586 (2008) 2903-2912.
    • (2008) J. Physiol. , vol.586 , pp. 2903-2912
    • Huang, Y.A.1    Maruyama, Y.2    Stimac, R.3    Roper, S.D.4
  • 40
    • 77955443637 scopus 로고    scopus 로고
    • The cell biology of taste
    • Chaudhari, N. and Roper, S.D. The cell biology of taste. J. Cell Biol. 190 (2010) 285-296.
    • (2010) J. Cell Biol. , vol.190 , pp. 285-296
    • Chaudhari, N.1    Roper, S.D.2
  • 41
    • 35148813068 scopus 로고    scopus 로고
    • Breadth of tuning and taste coding in mammalian taste buds
    • Tomchik, S.M., Berg, S., Kim, J.W., Chaudhari N. and Roper S.D. Breadth of tuning and taste coding in mammalian taste buds. J. Neurosci. 27 (2007) 10840-10848. DOI:10.1523/JNEUROSCI.1863-07.
    • (2007) J. Neurosci. , vol.27 , pp. 10840-10848
    • Tomchik, S.M.1    Berg, S.2    Kim, J.W.3    Chaudhari, N.4    Roper, S.D.5
  • 42
    • 84905845473 scopus 로고    scopus 로고
    • Heterogeneous binary interactions of taste primaries: Perceptual outcomes physiology and future directions
    • Wilkie, L.M. and Capaldi Phillips, E.D. Heterogeneous binary interactions of taste primaries: Perceptual outcomes, physiology, and future directions. Neurosci. Biobehav. Rev. 47C (2014) 70-86. DOI:10.1016/j.neubiorev. 2014.07.015.
    • (2014) Neurosci. Biobehav. Rev. , vol.47 C , pp. 70-86
    • Wilkie, L.M.1    Capaldi Phillips, E.D.2
  • 43
    • 79959259114 scopus 로고    scopus 로고
    • Genetics of taste and smell: Poisons and pleasures
    • Reed, D.R. and Knaapila, A. Genetics of taste and smell: poisons and pleasures. Progr. Mol. Biol. Transl. Sci. 94 (2010) 213-240.
    • (2010) Progr. Mol. Biol. Transl. Sci. , vol.94 , pp. 213-240
    • Reed, D.R.1    Knaapila, A.2
  • 44
    • 39049105701 scopus 로고    scopus 로고
    • Amiloride-sensitive channels in type i fungiform taste cells in mouse
    • Vandenbeuch, A., Clapp, T.R. and Kinnamon, S.C. Amiloride-sensitive channels in type I fungiform taste cells in mouse. BMC Neurosci. 9 (2008). DOI:10.1186/1471-2202-9-1.
    • (2008) BMC Neurosci. , vol.9
    • Vandenbeuch, A.1    Clapp, T.R.2    Kinnamon, S.C.3
  • 45
    • 84895487775 scopus 로고    scopus 로고
    • Peripheral coding of taste
    • Liman, E.R., Zhang, Y.V. and Montell, C. Peripheral coding of taste. Neuron 81 (2014) 984-1000.
    • (2014) Neuron , vol.81 , pp. 984-1000
    • Liman, E.R.1    Zhang, Y.V.2    Montell, C.3
  • 46
    • 79961126581 scopus 로고    scopus 로고
    • COMMD1 regulates the delta epithelial sodium channel (dENaC) through trafficking and ubiquitination
    • Chang, T., Ke, Y., Ly, K. and McDonald, F.J. COMMD1 regulates the delta epithelial sodium channel (dENaC) through trafficking and ubiquitination. Biochem. Biophys. Res. Commun. 411 (2011) 506-511.
    • (2011) Biochem. Biophys. Res. Commun. , vol.411 , pp. 506-511
    • Chang, T.1    Ke, Y.2    Ly, K.3    McDonald, F.J.4
  • 48
    • 4143072579 scopus 로고    scopus 로고
    • Acidsensitive two-pore domain potassium (K2P) channels in mouse taste buds
    • Richter, T.A., Dvoryanchikov, G.A., Chaudhari, N. and Roper, S.D. Acidsensitive two-pore domain potassium (K2P) channels in mouse taste buds. J. Neurophysiol. 92 (2004) 1928-1936.
    • (2004) J. Neurophysiol. , vol.92 , pp. 1928-1936
    • Richter, T.A.1    Dvoryanchikov, G.A.2    Chaudhari, N.3    Roper, S.D.4
  • 49
    • 48249144782 scopus 로고    scopus 로고
    • Functions of human bitter taste receptor depend on N-glycosylation
    • Reichling, C., Meyerhof, W. and Behrens, M. Functions of human bitter taste receptor depend on N-glycosylation. J. Neurochem. 106 (2008) 1138-1148.
    • (2008) J. Neurochem. , vol.106 , pp. 1138-1148
    • Reichling, C.1    Meyerhof, W.2    Behrens, M.3
  • 50
    • 77953892833 scopus 로고    scopus 로고
    • Oligomerization of TAS2R bitter taste receptors
    • Kuhn, C., Bufe, B., Batram, C. and Meyerhof, W. Oligomerization of TAS2R bitter taste receptors. Chem. Senses. 35 (2010) 395-406.
    • (2010) Chem. Senses. , vol.35 , pp. 395-406
    • Kuhn, C.1    Bufe, B.2    Batram, C.3    Meyerhof, W.4
  • 51
    • 84875615895 scopus 로고    scopus 로고
    • Bitter taste receptor research comes of age: From characterization to modulation of TAS2Rs
    • Behrens, M. and Meyerhof, W. Bitter taste receptor research comes of age: from characterization to modulation of TAS2Rs. Semin. Cell Dev. Biol. 24 (2013) 215-221.
    • (2013) Semin. Cell Dev. Biol. , vol.24 , pp. 215-221
    • Behrens, M.1    Meyerhof, W.2
  • 52
    • 27644564213 scopus 로고    scopus 로고
    • Taste recognition: Food for thought
    • Scott, K. Taste recognition: food for thought. Neuron 48 (2005) 455-464.
    • (2005) Neuron , vol.48 , pp. 455-464
    • Scott, K.1
  • 55
    • 0030435708 scopus 로고    scopus 로고
    • Interactions between umami and other flavor characteristics
    • Fuke, S. and Ueda, Y. Interactions between umami and other flavor characteristics. Trends Food Sci. Technol. 7 (1996) 407-411.
    • (1996) Trends Food Sci. Technol. , vol.7 , pp. 407-411
    • Fuke, S.1    Ueda, Y.2
  • 56
    • 33748481774 scopus 로고    scopus 로고
    • Taste perception and coding in the periphery
    • Sugita, M. Taste perception and coding in the periphery. Cell. Mol. Life Sci. 63 (2006) 2000-2015.
    • (2006) Cell. Mol. Life Sci. , vol.63 , pp. 2000-2015
    • Sugita, M.1
  • 57
    • 84875635849 scopus 로고    scopus 로고
    • Oral and extra-oral taste perception
    • Yamamoto, K. and Ishimaru, Y. Oral and extra-oral taste perception. Sem. Cell Dev. Biol. 24 (2013) 240-246.
    • (2013) Sem. Cell Dev. Biol. , vol.24 , pp. 240-246
    • Yamamoto, K.1    Ishimaru, Y.2
  • 58
    • 80053459477 scopus 로고    scopus 로고
    • Gustatory and extragustatory functions of mammalian taste receptors
    • Behrens, M. and Meyerhof, W. Gustatory and extragustatory functions of mammalian taste receptors. Physiol. Behav. 105 (2011) 4-13.
    • (2011) Physiol. Behav. , vol.105 , pp. 4-13
    • Behrens, M.1    Meyerhof, W.2
  • 59
    • 0035855939 scopus 로고    scopus 로고
    • Receptors and transduction in taste
    • Lindemann, B. Receptors and transduction in taste. Nature 413 (2001) 219-225.
    • (2001) Nature , vol.413 , pp. 219-225
    • Lindemann, B.1
  • 60
    • 67649875867 scopus 로고    scopus 로고
    • Interactions of the sweet-tasting proteins thaumatin and lysozyme with the human sweet-taste receptor
    • Ide, N., Sato, E., Ohta, K., Masuda, T. and Kitabatake, N. Interactions of the sweet-tasting proteins thaumatin and lysozyme with the human sweet-taste receptor. J. Agric. Food Chem. 57 (2009) 5884-5890.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 5884-5890
    • Ide, N.1    Sato, E.2    Ohta, K.3    Masuda, T.4    Kitabatake, N.5
  • 61
    • 77955615606 scopus 로고    scopus 로고
    • Pseudogenization of a sweet receptor gene accounts for cats' indifference toward sugar
    • Li, X., Li, W., Wang, H., Cao, J., Maehashi, K. and Huang, L. Pseudogenization of a sweet receptor gene accounts for cats' indifference toward sugar. PLoS Genet. 1 (2005) 27-35.
    • (2005) PLoS Genet. , vol.1 , pp. 27-35
    • Li, X.1    Li, W.2    Wang, H.3    Cao, J.4    Maehashi, K.5    Huang, L.6
  • 62
    • 36749099088 scopus 로고    scopus 로고
    • The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor
    • Winnig, M., Bufe, B., Kratochwil, N.A., Slack, J.P. and Meyerhof, W. The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor. BMC Struct. Biol. 7 (2007). DOI:10.1186/1472-6807-7-66.
    • (2007) BMC Struct. Biol. , vol.7
    • Winnig, M.1    Bufe, B.2    Kratochwil, N.A.3    Slack, J.P.4    Meyerhof, W.5
  • 63
    • 30744472932 scopus 로고    scopus 로고
    • Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes
    • Shi, P. and Zhang, J. Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes. Mol. Biol. Evol. 23 (2006) 292-300.
    • (2006) Mol. Biol. Evol. , vol.23 , pp. 292-300
    • Shi, P.1    Zhang, J.2
  • 65
    • 80053489155 scopus 로고    scopus 로고
    • Taste isn't just for taste buds anymore
    • Finger, T.E. and Kinnamon, S.C. Taste isn't just for taste buds anymore. F1000 Biol. Rep. 3 (2011). DOI: 10.3410/B3-20.
    • (2011) F1000 Biol. Rep. , vol.3
    • Finger, T.E.1    Kinnamon, S.C.2
  • 66
    • 84897996546 scopus 로고    scopus 로고
    • Differential expression of bitter taste receptors in non-cancerous breast epithelial and breast cancer cells
    • Singh, N., Chakraborty, R., Bhullar, R.P. and Chelikani, P. Differential expression of bitter taste receptors in non-cancerous breast epithelial and breast cancer cells. Biochem. Biophys. Res. Commun. 446 (2014) 499-503.
    • (2014) Biochem. Biophys. Res. Commun. , vol.446 , pp. 499-503
    • Singh, N.1    Chakraborty, R.2    Bhullar, R.P.3    Chelikani, P.4
  • 68
    • 84905571552 scopus 로고    scopus 로고
    • Bitter taste receptor (TAS2R) agonists inhibit IgE-dependent mast cell activation
    • Epub 2014 Apr 19
    • Ekoff, M., Choi, J.H., James, A., Dahlén, B., Nilsson, G. and Dahlén, S.E. Bitter taste receptor (TAS2R) agonists inhibit IgE-dependent mast cell activation. J. Allergy Clin. Immunol. 134 (2014) 475-478. DOI: 10.1016/j.jaci.2014.02.029. Epub 2014 Apr 19.
    • (2014) J. Allergy Clin. Immunol. , vol.134 , pp. 475-478
    • Ekoff, M.1    Choi, J.H.2    James, A.3    Dahlén, B.4    Nilsson, G.5    Dahlén, S.E.6
  • 69
    • 84896691815 scopus 로고    scopus 로고
    • Extrasensory perception: Odorant and taste receptors beyond the nose and mouth
    • Foster, S.R., Roura, E. and Thomas, W.G. Extrasensory perception: odorant and taste receptors beyond the nose and mouth. Pharmacol. Ther. 142 (2013) 41-61.
    • (2013) Pharmacol. Ther. , vol.142 , pp. 41-61
    • Foster, S.R.1    Roura, E.2    Thomas, W.G.3
  • 71
    • 77957739610 scopus 로고    scopus 로고
    • Oral and extraoral bitter taste receptors
    • Behrens, M. and Meyerhof, W. Oral and extraoral bitter taste receptors. Results Probl. Cell Differ. 52 (2010) 87-99. DOI: 10.1007/978-3-642-14426-4-8.
    • (2010) Results Probl. Cell Differ. , vol.52 , pp. 87-99
    • Behrens, M.1    Meyerhof, W.2
  • 74
    • 33847078811 scopus 로고    scopus 로고
    • Taste receptors in the gastrointestinal tract. IV. Functional implications of bitter taste receptors in gastrointestinal chemosensing. Am. J. Physiol. Gastrointest
    • Sternini, C. Taste receptors in the gastrointestinal tract. IV. Functional implications of bitter taste receptors in gastrointestinal chemosensing. Am. J. Physiol. Gastrointest. Liver Physiol. 292 (2007) G457-461. DOI: 10.1152/ajpgi.00411.2006.
    • (2007) Liver Physiol. , vol.292 , pp. G457-461
    • Sternini, C.1
  • 75
    • 79952138344 scopus 로고    scopus 로고
    • Bitter taste receptors and-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying
    • Janssen, S., Laermans, J., Verhulst, P.J., Thijs, T., Tack, J. and Depoortere, I. Bitter taste receptors and-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying. Proc. Natl. Acad. Sci. USA 108 (2011) 2094-2099.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 2094-2099
    • Janssen, S.1    Laermans, J.2    Verhulst, P.J.3    Thijs, T.4    Tack, J.5    Depoortere, I.6
  • 76
    • 84870314938 scopus 로고    scopus 로고
    • Extraoral bitter taste receptors as mediators of off-target drug effects
    • Clark, A.A., Liggett, S.B. and Munger, S.D. Extraoral bitter taste receptors as mediators of off-target drug effects. FASEB J. 26 (2012) 4827-4831.
    • (2012) FASEB J. , vol.26 , pp. 4827-4831
    • Clark, A.A.1    Liggett, S.B.2    Munger, S.D.3
  • 77
    • 84861754565 scopus 로고    scopus 로고
    • Depletion of bitter taste transduction leads to massive spermatid loss in transgenic mice
    • Li, F. and Zhou, M. Depletion of bitter taste transduction leads to massive spermatid loss in transgenic mice. Mol. Hum. Reprod. 18 (2012) 289-297.
    • (2012) Mol. Hum. Reprod. , vol.18 , pp. 289-297
    • Li, F.1    Zhou, M.2
  • 80
    • 72449180982 scopus 로고    scopus 로고
    • Sweet taste signaling functions as a hypothalamic glucose sensor
    • eCollection 2009
    • Ren, X., Zhou, L., Terwilliger, R., Newton, S.S. and de Araujo, I.E. Sweet taste signaling functions as a hypothalamic glucose sensor. Front. Integr. Neurosci. 3 (2009). DOI: 10.3389/neuro.07.012.2009. eCollection 2009.
    • (2009) Front. Integr. Neurosci. , vol.3
    • Ren, X.1    Zhou, L.2    Terwilliger, R.3    Newton, S.S.4    De Araujo, I.E.5
  • 81
    • 0037016771 scopus 로고    scopus 로고
    • Molecular mechanisms of bitter and sweet taste transduction
    • Margolskee, R.F. Molecular mechanisms of bitter and sweet taste transduction. J. Biol. Chem. 277 (2002) 1-4.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1-4
    • Margolskee, R.F.1
  • 82
    • 84926611558 scopus 로고    scopus 로고
    • Denatonium induces secretion of glucagon-like peptide-1 through activation of bitter taste receptor pathways
    • Kim, K.S., Egan, J.M. and Jang, H.J. Denatonium induces secretion of glucagon-like peptide-1 through activation of bitter taste receptor pathways. Diabetologia 57 (2014) 2117-2125.
    • (2014) Diabetologia , vol.57 , pp. 2117-2125
    • Kim, K.S.1    Egan, J.M.2    Jang, H.J.3
  • 85
    • 0035789507 scopus 로고    scopus 로고
    • Immunocyto-chemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transduction
    • Clapp, T.R., Stone, L.M., Margolskee, R.F. and Kinnamon, S.C. Immunocyto-chemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transduction. BMC Neurosci. 2 (2001). DOI:10.1186/1471-2202-2-6.
    • (2001) BMC Neurosci. , vol.2
    • Clapp, T.R.1    Stone, L.M.2    Margolskee, R.F.3    Kinnamon, S.C.4
  • 87
    • 84892475366 scopus 로고    scopus 로고
    • Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice
    • Sclafani, A., Marambaud, P. and Ackroff, K. Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice. Physiol. Behav. 126 (2014) 25-29. DOI: 10.1016/j.physbeh.2013.12.003.
    • (2014) Physiol. Behav. , vol.126 , pp. 25-29
    • Sclafani, A.1    Marambaud, P.2    Ackroff, K.3
  • 88
    • 84874773135 scopus 로고    scopus 로고
    • Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins and innexins
    • Siebert, A.P. Ma, Z., Grevet, J.D., Demuro, A., Parker, I. and Foskett, J.K. Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins and innexins. J. Biol. Chem. 288 (2013) 6140-6153.
    • (2013) J. Biol. Chem. , vol.288 , pp. 6140-6153
    • Siebert, A.P.1    Ma, Z.2    Grevet, J.D.3    Demuro, A.4    Parker, I.5    Foskett, J.K.6
  • 89
    • 72549091458 scopus 로고    scopus 로고
    • Cell-to-cell communication in intact taste buds through ATP signalling from pannexin 1 gap junction hemichannels
    • Dando, R. and Roper, S.D. Cell-to-cell communication in intact taste buds through ATP signalling from pannexin 1 gap junction hemichannels. J. Physiol. 587 (2009) 5899-5906. DOI: 10.1113/jphysiol.2009.180083.
    • (2009) J. Physiol. , vol.587 , pp. 5899-5906
    • Dando, R.1    Roper, S.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.