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Volumn 9, Issue 2, 2015, Pages 126-140

The FKBP51-glucocorticoid receptor balance in stress-related mental disorders

Author keywords

FKBP51; Glucocorticoid receptor; HPA axis; Mental disorders; Stress

Indexed keywords

FK 506 BINDING PROTEIN; GLUCOCORTICOID RECEPTOR; TACROLIMUS BINDING PROTEIN 5;

EID: 84960952235     PISSN: 18744672     EISSN: 18744702     Source Type: Journal    
DOI: 10.2174/1874467208666150519114435     Document Type: Article
Times cited : (37)

References (188)
  • 1
    • 0021988845 scopus 로고
    • Development of a monoclonal antibody to the rabbit 8.5S uterine progestin receptor
    • Nakao, K.; Myers, J.E.; Faber, L.E. Development of a monoclonal antibody to the rabbit 8.5S uterine progestin receptor. Can. J. Biochem. Cell Biol., 1985, 63, 33-40.
    • (1985) Can. J. Biochem. Cell Biol. , vol.63 , pp. 33-40
    • Nakao, K.1    Myers, J.E.2    Faber, L.E.3
  • 2
    • 0025233648 scopus 로고
    • Purification of unactivated progesterone receptor and identification of novel receptorassociated proteins
    • Smith, D.F.; Faber, L.E.; Toft, D.O. Purification of unactivated progesterone receptor and identification of novel receptorassociated proteins. J. Biol. Chem., 1990, 265, 3996-4003.
    • (1990) J. Biol. Chem. , vol.265 , pp. 3996-4003
    • Smith, D.F.1    Faber, L.E.2    Toft, D.O.3
  • 3
    • 0025605444 scopus 로고
    • Hsp56: A novel heat shock protein associated with untransformed steroid receptor complexes 348
    • Sanchez, E.R. Hsp56: a novel heat shock protein associated with untransformed steroid receptor complexes 348. J. Biol. Chem., 1990, 265, 22067-22070.
    • (1990) J. Biol. Chem. , vol.265 , pp. 22067-22070
    • Sanchez, E.R.1
  • 4
    • 0031053574 scopus 로고    scopus 로고
    • Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor 200
    • Nair, S.C.; Rimerman, R.A.; Toran, E.J.; Chen, S.; Prapapanich, V.; Butts, R.N.; Smith, D.F. Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor 200. Mol. Cell Biol., 1997, 17, 594-603.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 594-603
    • Nair, S.C.1    Rimerman, R.A.2    Toran, E.J.3    Chen, S.4    Prapapanich, V.5    Butts, R.N.6    Smith, D.F.7
  • 5
    • 57149093203 scopus 로고    scopus 로고
    • FKBP family proteins: Immunophilins with versatile biological functions
    • Kang, C.B.; Hong, Y.; Dhe-Paganon, S.; Yoon, H.S. FKBP family proteins: immunophilins with versatile biological functions. Neurosignals, 2008, 16, 318-325.
    • (2008) Neurosignals , vol.16 , pp. 318-325
    • Kang, C.B.1    Hong, Y.2    Dhe-Paganon, S.3    Yoon, H.S.4
  • 6
    • 0034968225 scopus 로고    scopus 로고
    • J. Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40
    • Pirkl, F. Buchner, J. Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40. J. Mol. Biol., 2001, 308, 795-806.
    • (2001) J. Mol. Biol. , vol.308 , pp. 795-806
    • Pirkl, F.B.1
  • 8
    • 0030925683 scopus 로고    scopus 로고
    • D.O. Steroid receptor interactions with heat shock protein and immunophilin chaperones
    • Pratt, W.B. Toft, D.O. Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr. Rev., 1997, 18, 306-360.
    • (1997) Endocr. Rev. , vol.18 , pp. 306-360
    • Pratt, W.B.T.1
  • 9
    • 0033601331 scopus 로고    scopus 로고
    • Different Regions of the Immunophilin FKBP52 Determine Its Association with the Glucocorticoid Receptor, hsp90, and Cytoplasmic Dynein
    • Silverstein, A.M.; Galigniana, M.D.; Kanelakis, K.C.; Radanyi, C.; Renoir, J.M.; Pratt, W.B. Different Regions of the Immunophilin FKBP52 Determine Its Association with the Glucocorticoid Receptor, hsp90, and Cytoplasmic Dynein. J. Biol. Chem.. 1999, 274, 36980-36986.
    • (1999) J. Biol. Chem.. , vol.274 , pp. 36980-36986
    • Silverstein, A.M.1    Galigniana, M.D.2    Kanelakis, K.C.3    Radanyi, C.4    Renoir, J.M.5    Pratt, W.B.6
  • 13
    • 0021278360 scopus 로고
    • Adaptation of the mineralocorticoid target tissues to the high circulating cortisol and progesterone plasma levels in the squirrel monkey
    • Chrousos, G. P.; Loriaux, D. L.; Brandon, D.; Shull, J.; Renquist, D.; Hogan, W.; Tomita, M.; Lipsett, M.B. Adaptation of the mineralocorticoid target tissues to the high circulating cortisol and progesterone plasma levels in the squirrel monkey. Endocrinology, 1984, 115, 25-32.
    • (1984) Endocrinology , vol.115 , pp. 25-32
    • Chrousos, G.P.1    Loriaux, D.L.2    Brandon, D.3    Shull, J.4    Renquist, D.5    Hogan, W.6    Tomita, M.7    Lipsett, M.B.8
  • 14
    • 0031016398 scopus 로고    scopus 로고
    • Cloning and expression of the glucocorticoid receptor from the squirrel monkey (Saimiri boliviensis boliviensis), a glucocorticoid-resistant primate
    • Reynolds, P.D.; Pittler, S.J.; Scammell, J.G. Cloning and expression of the glucocorticoid receptor from the squirrel monkey (Saimiri boliviensis boliviensis), a glucocorticoid-resistant primate. J. Clin. Endocrinol. Metab., 1997, 82, 465-472.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 465-472
    • Reynolds, P.D.1    Pittler, S.J.2    Scammell, J.G.3
  • 15
    • 0033018628 scopus 로고    scopus 로고
    • Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51
    • Reynolds, P. D.; Ruan, Y.; Smith, D. F.; Scammell, J. G. (1999). Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51. J. Clin. Endocrinol. Metab., 84, 663-669.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 663-669
    • Reynolds, P.D.1    Ruan, Y.2    Smith, D.F.3    Scammell, J.G.4
  • 16
    • 0033712280 scopus 로고    scopus 로고
    • Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding
    • Denny, W.B.; Valentine, D.L.; Reynolds, P.D.; Smith, D.F.; Scammell, J.G. Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding. Endocrinology, 2000, 141, 4107-4113.
    • (2000) Endocrinology , vol.141 , pp. 4107-4113
    • Denny, W.B.1    Valentine, D.L.2    Reynolds, P.D.3    Smith, D.F.4    Scammell, J.G.5
  • 18
    • 14244262261 scopus 로고    scopus 로고
    • FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells
    • Wochnik, G.M.; Rüegg, J.; Abel, G.A.; Schmidt, U.; Holsboer, F.; Rein, T. FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells. J. Biol. Chem., 2005, 280, 4609-4616.
    • (2005) J. Biol. Chem. , vol.280 , pp. 4609-4616
    • Wochnik, G.M.1    Rüegg, J.2    Abel, G.A.3    Schmidt, U.4    Holsboer, F.5    Rein, T.6
  • 20
    • 67849100994 scopus 로고    scopus 로고
    • Modulation of glucocorticoid receptor nuclear translocation in neurons by immunophilins FKBP51 and FKBP52: Implications for major depressive disorder
    • Tatro, E.T.; Everall, I.P.; Kaul, M.; Achim, C.L. Modulation of glucocorticoid receptor nuclear translocation in neurons by immunophilins FKBP51 and FKBP52: implications for major depressive disorder. Brain Res., 2009, 1286, 1-12.
    • (2009) Brain Res. , vol.1286 , pp. 1-12
    • Tatro, E.T.1    Everall, I.P.2    Kaul, M.3    Achim, C.L.4
  • 21
    • 0035805599 scopus 로고    scopus 로고
    • Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus
    • Galigniana, M.D.; Radanyi, C.; Renoir, J.M.; Housley, P.R.; Pratt, W. B. Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus. J. Biol. Chem., 2001, 276, 14884-14889.
    • (2001) J. Biol. Chem. , vol.276 , pp. 14884-14889
    • Galigniana, M.D.1    Radanyi, C.2    Renoir, J.M.3    Housley, P.R.4    Pratt, W.B.5
  • 22
    • 37049025017 scopus 로고    scopus 로고
    • Differential recruitment of tetratricorpeptide repeat domain immunophilins to the mineralocorticoid receptor influences both heat-shock protein 90-dependent retrotransport and hormone-dependent transcriptional activity
    • Gallo, L.I.; Ghini, A.A.; Pilipuk, G.P.; Galigniana, M.D. Differential recruitment of tetratricorpeptide repeat domain immunophilins to the mineralocorticoid receptor influences both heat-shock protein 90-dependent retrotransport and hormone-dependent transcriptional activity. Biochemistry, 2007, 46, 14044-14057.
    • (2007) Biochemistry , vol.46 , pp. 14044-14057
    • Gallo, L.I.1    Ghini, A.A.2    Pilipuk, G.P.3    Galigniana, M.D.4
  • 23
    • 34548485298 scopus 로고    scopus 로고
    • The immunophilin FKBP52 specifically binds to tubulin and prevents microtubule formation
    • Chambraud, B.; Belabes, H.; Fontaine-Lenoir, V.; Fellous, A.; Baulieu, E.E. The immunophilin FKBP52 specifically binds to tubulin and prevents microtubule formation. FASEB J., 2007, 21, 2787-2797.
    • (2007) FASEB J. , vol.21 , pp. 2787-2797
    • Chambraud, B.1    Belabes, H.2    Fontaine-Lenoir, V.3    Fellous, A.4    Baulieu, E.E.5
  • 25
    • 78651322182 scopus 로고    scopus 로고
    • Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth
    • Quinta, H. R.; Maschi, D.; Gomez-Sanchez, C.; Piwien-Pilipuk, G.; and Galigniana, M. D. (2010). Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth. J. Neurochem., 2010, 115, 716-734.
    • (2010) J. Neurochem. , vol.2010 , Issue.115 , pp. 716-734
    • Quinta, H.R.1    Maschi, D.2    Gomez-Sanchez, C.3    Piwien-Pilipuk, G.4    Galigniana, M.D.5
  • 27
    • 76749092246 scopus 로고    scopus 로고
    • The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events
    • Galigniana, M.D.; Erlejman, A.G.; Monte, M.; Gomez-Sanchez, C.; Piwien-Pilipuk, G. The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events. Mol. Cell Biol., 2010, 30, 1285-1298.
    • (2010) Mol. Cell Biol. , vol.30 , pp. 1285-1298
    • Galigniana, M.D.1    Erlejman, A.G.2    Monte, M.3    Gomez-Sanchez, C.4    Piwien-Pilipuk, G.5
  • 28
    • 37549067731 scopus 로고    scopus 로고
    • Noncatalytic role of the FKBP52 peptidyl-prolyl isomerase domain in the regulation of steroid hormone signaling
    • Riggs, D.L.; Cox, M.B.; Tardif, H.L.; Hessling, M.; Buchner, J.; Smith, D.F. Noncatalytic role of the FKBP52 peptidyl-prolyl isomerase domain in the regulation of steroid hormone signaling. Mol. Cell Biol., 2007, 27, 8658-8669.
    • (2007) Mol. Cell Biol. , vol.27 , pp. 8658-8669
    • Riggs, D.L.1    Cox, M.B.2    Tardif, H.L.3    Hessling, M.4    Buchner, J.5    Smith, D.F.6
  • 29
    • 0032230312 scopus 로고    scopus 로고
    • Analysis of FKBP51/FKBP52 chimeras and mutants for Hsp90 binding and association with progesterone receptor complexes
    • Barent, R.L.; Nair, S.C.; Carr, D.C.; Ruan, Y.; Rimerman, R.A.; Fulton, J.; Zhang, Y.; Smith, D.F. Analysis of FKBP51/FKBP52 chimeras and mutants for Hsp90 binding and association with progesterone receptor complexes. Mol. Endocrinol.. 1998, 12, 342-354.
    • (1998) Mol. Endocrinol.. , vol.12 , pp. 342-354
    • Barent, R.L.1    Nair, S.C.2    Carr, D.C.3    Ruan, Y.4    Rimerman, R.A.5    Fulton, J.6    Zhang, Y.7    Smith, D.F.8
  • 31
    • 2942593899 scopus 로고    scopus 로고
    • 3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/ Hsp90/immunophilin heterocomplex.
    • Wu, B.; Li, P.; Liu, Y.; Lou, Z.; Ding, Y.; Shu, C.; Ye, S.; Bartlam, M.; Shen, B.; Rao, Z. 3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/ Hsp90/immunophilin heterocomplex. Proc. Natl. Acad.Sci.USA, 2004, 101, 8348-8353.
    • (2004) Proc. Natl. Acad.Sci.Usa , vol.101 , pp. 8348-8353
    • Wu, B.1    Li, P.2    Liu, Y.3    Lou, Z.4    Ding, Y.5    Shu, C.6    Ye, S.7    Bartlam, M.8    Shen, B.9    Rao, Z.10
  • 32
    • 0345144024 scopus 로고    scopus 로고
    • Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes
    • Sinars, C.R.; Cheung-Flynn, J.; Rimerman, R.A.; Scammell, J.G.; Smith, D.F.; Clardy, J. Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes. Proc. Natl. Acad. Sci. USA, 2003, 100, 868-873.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 868-873
    • Sinars, C.R.1    Cheung-Flynn, J.2    Rimerman, R.A.3    Scammell, J.G.4    Smith, D.F.5    Clardy, J.6
  • 33
    • 84902355198 scopus 로고    scopus 로고
    • Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52.
    • Mustafi, S.M.; LeMaster, D.M.; Hernandez, G. Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52. Biochem. J., 2041, 461, 115-123.
    • Biochem. J. , vol.461 , pp. 115-123
    • Mustafi, S.M.1    Lemaster, D.M.2    Hernandez, G.3
  • 34
    • 22144494187 scopus 로고    scopus 로고
    • Structure-function analysis of squirrel monkey FK506-binding protein 51, a potent inhibitor of glucocorticoid receptor activity
    • Denny, W.B.; Prapapanich, V.; Smith, D.F.; Scammell, J.G. Structure-function analysis of squirrel monkey FK506-binding protein 51, a potent inhibitor of glucocorticoid receptor activity. Endocrinology, 2005, 146, 3194-3201.
    • (2005) Endocrinology , vol.146 , pp. 3194-3201
    • Denny, W.B.1    Prapapanich, V.2    Smith, D.F.3    Scammell, J.G.4
  • 35
    • 0031668309 scopus 로고    scopus 로고
    • (1-1-1998). Glucocorticoid-resistant Blymphoblast cell line derived from the Bolivian squirrel monkey (Saimiri boliviensis boliviensis)
    • Reynolds, P.D.; Roveda, K. P.; Tucker, J.A.; Moore, C.M.; Valentine, D.L.; Scammell, J.G. (1-1-1998). Glucocorticoid-resistant Blymphoblast cell line derived from the Bolivian squirrel monkey (Saimiri boliviensis boliviensis). Lab. Anim. Sci., 48, 364-370.
    • Lab. Anim. Sci. , vol.48 , pp. 364-370
    • Reynolds, P.D.1    Roveda, K.P.2    Tucker, J.A.3    Moore, C.M.4    Valentine, D.L.5    Scammell, J.G.6
  • 36
    • 0031575750 scopus 로고    scopus 로고
    • Tissue distribution and abundance of human FKBP51, and FK506-binding protein that can mediate calcineurin inhibition
    • Baughman, G.; Wiederrecht, G.J.; Chang, F.; Martin, M.M.; Bourgeois, S. Tissue distribution and abundance of human FKBP51, and FK506-binding protein that can mediate calcineurin inhibition. Biochem. Biophys. Res. Communi., 1997, 232, 437-443.
    • (1997) Biochem. Biophys. Res. Communi. , vol.232 , pp. 437-443
    • Baughman, G.1    Wiederrecht, G.J.2    Chang, F.3    Martin, M.M.4    Bourgeois, S.5
  • 37
    • 0024309040 scopus 로고
    • Isolation and characterization of glucocorticoid-and cyclic AMP-induced genes in T lymphocytes.
    • Harrigan, M.T.; Baughman, G.; Campbell, N.F.; Bourgeois, S. (1989). Isolation and characterization of glucocorticoid-and cyclic AMP-induced genes in T lymphocytes. Mol. Cell Biol., 9, 3438-3446.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 3438-3446
    • Harrigan, M.T.1    Baughman, G.2    Campbell, N.F.3    Bourgeois, S.4
  • 38
    • 79951775578 scopus 로고    scopus 로고
    • Expression and regulation of the Fkbp5 gene in the adult mouse brain
    • e16883
    • Scharf, S.H.; Liebl, C.; Binder, E.B.; Schmidt, M.V.; Muller, M.B. Expression and regulation of the Fkbp5 gene in the adult mouse brain. PLoS One, 2011, 6, e16883.
    • (2011) Plos One , pp. 6
    • Scharf, S.H.1    Liebl, C.2    Binder, E.B.3    Schmidt, M.V.4    Muller, M.B.5
  • 40
    • 77956053977 scopus 로고    scopus 로고
    • Chronic corticosterone exposure increases expression and decreases deoxyribonucleic acid methylation of Fkbp5 in mice
    • Lee, R.S.; Tamashiro, K.L.; Yang, X.; Purcell, R.H.; Harvey, A.; Willour, V.L.; Huo, Y.; Rongione, M.; W,G.S. Potash, J.B. Chronic corticosterone exposure increases expression and decreases deoxyribonucleic acid methylation of Fkbp5 in mice. Endocrinology, 2010, 151, 4332-4343.
    • (2010) Endocrinology , vol.151 , pp. 4332-4343
    • Lee, R.S.1    Tamashiro, K.L.2    Yang, X.3    Purcell, R.H.4    Harvey, A.5    Willour, V.L.6    Huo, Y.7    Rongione, M.8    Potash, J.B.9
  • 41
    • 7644219666 scopus 로고    scopus 로고
    • Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids
    • Hubler, T.R. Scammell, J.G. Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids. Cell Stress Chaperones, 2004, 9, 243-252.
    • (2004) Cell Stress Chaperones , vol.9 , pp. 243-252
    • Hubler, T.R.1    Scammell, J.G.2
  • 42
    • 77249119220 scopus 로고    scopus 로고
    • Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions. Mol
    • Paakinaho, V.; Makkonen, H.; Jaaskelainen, T.; Palvimo, J.J. Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions. Mol. Endocrinol., 2010, 24, 511-525.
    • (2010) Endocrinol. , vol.24 , pp. 511-525
    • Paakinaho, V.1    Makkonen, H.2    Jaaskelainen, T.3    Palvimo, J.J.4
  • 44
    • 80051671580 scopus 로고    scopus 로고
    • Steroid upregulation of FKBP51 and its role in hormone signaling
    • Jääskeläinen, T.; Makkonen, H.; Palvimo, J.J. Steroid upregulation of FKBP51 and its role in hormone signaling. Curr. Opin. Pharmacol., 2011, 11, 326-331.
    • (2011) Curr. Opin. Pharmacol. , vol.11 , pp. 326-331
    • Jääskeläinen, T.1    Makkonen, H.2    Palvimo, J.J.3
  • 45
    • 67651180792 scopus 로고    scopus 로고
    • Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers
    • Makkonen, H.; Kauhanen, M.; Paakinaho, V.; Jaaskelainen, T.; Palvimo, J. J. (2009). Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers. Nucleic Acids Res., 37, 4135-4148.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 4135-4148
    • Makkonen, H.1    Kauhanen, M.2    Paakinaho, V.3    Jaaskelainen, T.4    Palvimo, J.J.5
  • 46
    • 0037900196 scopus 로고    scopus 로고
    • The FK506-Binding Immunophilin FKBP51 Is Transcriptionally Regulated by Progestin and Attenuates Progestin Responsiveness
    • Hubler, T. R.; Denny, W. B.; Valentine, D. L.; Cheung-Flynn, J.; Smith, D. F.; Scammell, J. G. (2003). The FK506-Binding Immunophilin FKBP51 Is Transcriptionally Regulated by Progestin and Attenuates Progestin Responsiveness. Endocrinology, 144, 2380-2387.
    • (2003) Endocrinology , vol.144 , pp. 2380-2387
    • Hubler, T.R.1    Denny, W.B.2    Valentine, D.L.3    Cheung-Flynn, J.4    Smith, D.F.5    Scammell, J.G.6
  • 47
    • 29344467436 scopus 로고    scopus 로고
    • Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element
    • Magee, J.A.; Chang, L.W.; Stormo, G.D.; Milbrandt, J. Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element. Endocrinology, 2006, 147, 590-598.
    • (2006) Endocrinology , vol.147 , pp. 590-598
    • Magee, J.A.1    Chang, L.W.2    Stormo, G.D.3    Milbrandt, J.4
  • 49
    • 2342529037 scopus 로고    scopus 로고
    • A note on clustering the functionally-related paralogues and orthologues of proteins: A case of the FK506-binding proteins (FKBPs)
    • Galat, A. A note on clustering the functionally-related paralogues and orthologues of proteins: a case of the FK506-binding proteins (FKBPs). Comput. Biol. Chem., 2004, 28, 129-140.
    • (2004) Comput. Biol. Chem. , vol.28 , pp. 129-140
    • Galat, A.1
  • 50
    • 80051663514 scopus 로고    scopus 로고
    • Organization and function of the FKBP52 and FKBP51 genes
    • Cioffi, D.L.; Hubler, T.R.; Scammell, J.G. Organization and function of the FKBP52 and FKBP51 genes. Curr. Opin. Pharmacol., 2011, 11, 308-313.
    • (2011) Curr. Opin. Pharmacol. , vol.11 , pp. 308-313
    • Cioffi, D.L.1    Hubler, T.R.2    Scammell, J.G.3
  • 51
    • 0037244704 scopus 로고    scopus 로고
    • Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: A potential marker for glucocorticoid sensitivity, potency, and bioavailability
    • Vermeer, H.; Hendriks-Stegeman, B.I.; van der Burg, B.; Van Buul-Offers, S.C.; Jansen, M. Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability. J. Clin. Endocrinol. Metab., 2003, 88, 277-284.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 277-284
    • Vermeer, H.1    Hendriks-Stegeman, B.I.2    Van Der Burg, B.3    Van Buul-Offers, S.C.4    Jansen, M.5
  • 52
    • 84876140223 scopus 로고    scopus 로고
    • Allele-specific epigenetic modification: A molecular mechanism for gene-environment interactions in stressrelated psychiatric disorders?
    • Klengel, T. Binder, E.B. Allele-specific epigenetic modification: a molecular mechanism for gene-environment interactions in stressrelated psychiatric disorders? Epigenomics, 2013, 5, 109-112.
    • (2013) Epigenomics , vol.5 , pp. 109-112
    • Klengel, T.1    Binder, E.B.2
  • 54
    • 84883184667 scopus 로고    scopus 로고
    • Previous history of chronic stress changes the transcriptional response to glucocorticoid challenge in the dentate gyrus region of the male rat hippocampus
    • Datson, N.A.; van den Oever, J.M.; Korobko, O.B.; Magarinos, A. M.; De Kloet, E.R.; McEwen, B.S. Previous history of chronic stress changes the transcriptional response to glucocorticoid challenge in the dentate gyrus region of the male rat hippocampus. Endocrinology, 2013, 154, 3261-3272.
    • (2013) Endocrinology , vol.154 , pp. 3261-3272
    • Datson, N.A.1    Van Den Oever, J.M.2    Korobko, O.B.3    Magarinos, A.M.4    De Kloet, E.R.5    McEwen, B.S.6
  • 59
    • 84857042430 scopus 로고    scopus 로고
    • Chaperoning steroidal physiology: Lessons from mouse genetic models of Hsp90 and its cochaperones
    • Sanchez, E.R. Chaperoning steroidal physiology: lessons from mouse genetic models of Hsp90 and its cochaperones. Biochim. Biophys. Acta., 2012, 1823, 722-729.
    • (2012) Biochim. Biophys. Acta. , vol.1823 , pp. 722-729
    • Sanchez, E.R.1
  • 60
    • 17144370286 scopus 로고    scopus 로고
    • Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer
    • Febbo, P.G.; Lowenberg, M.; Thorner, A.R.; Brown, M.; Loda, M.; Golub, T.R. (2005). Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer. J. Urol., 2005, 173, 1772-1777.
    • (2005) J. Urol. , vol.2005 , Issue.173 , pp. 1772-1777
    • Febbo, P.G.1    Lowenberg, M.2    Thorner, A.R.3    Brown, M.4    Loda, M.5    Golub, T.R.6
  • 61
    • 76749108107 scopus 로고    scopus 로고
    • FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells
    • Ni, L.; Yang, C.S.; Gioeli, D.; Frierson, H.; Toft, D.O.; Paschal, B.M. FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells. Mol. Cell Biol., 2010, 30, 1243-1253.
    • (2010) Mol. Cell Biol. , vol.30 , pp. 1243-1253
    • Ni, L.1    Yang, C.S.2    Gioeli, D.3    Frierson, H.4    Toft, D.O.5    Paschal, B.M.6
  • 62
    • 77949654801 scopus 로고    scopus 로고
    • FKBP51 and Cyp40 are positive regulators of androgendependent prostate cancer cell growth and the targets of FK506 and cyclosporin A
    • Periyasamy, S.; Hinds, T.; Jr.; Shemshedini, L.; Shou, W.; Sanchez, E.R. FKBP51 and Cyp40 are positive regulators of androgendependent prostate cancer cell growth and the targets of FK506 and cyclosporin A. Oncogene, 2010, 29, 1691-1701.
    • (2010) Oncogene , vol.29 , pp. 1691-1701
    • Periyasamy, S.1    Hinds, T.2    Shemshedini, L.3    Shou, W.4    Sanchez, E.R.5
  • 66
    • 18844437230 scopus 로고    scopus 로고
    • On the interactions of the hypothalamic-pituitary-adrenal (HPA) axis and sleep: Normal HPA axis activity and circadian rhythm, exemplary sleep disorders
    • Buckley, T.M. Schatzberg, A.F. On the interactions of the hypothalamic-pituitary-adrenal (HPA) axis and sleep: normal HPA axis activity and circadian rhythm, exemplary sleep disorders. J. Clin. Endocrinol. Metab., 2005, 90, 3106-3114.
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 3106-3114
    • Buckley, T.M.1    Schatzberg, A.F.2
  • 71
    • 43449094351 scopus 로고    scopus 로고
    • Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease
    • Thornalley, P.J. Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease. Drug Metabol. Drug Interact., 2008, 23, 125-150.
    • (2008) Drug Metabol. Drug Interact. , vol.23 , pp. 125-150
    • Thornalley, P.J.1
  • 72
    • 84875842853 scopus 로고    scopus 로고
    • Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: Recent advances and mechanistic insights
    • Distler, M.G. Palmer, A.A. (2012). Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights. Front Genet. 3, 250.
    • (2012) Front Genet , vol.3 , pp. 250
    • Distler, M.G.1    Palmer, A.A.2
  • 77
    • 79955013404 scopus 로고    scopus 로고
    • Evidence for prospective associations among depression and obesity in population-based studies
    • Faith, M.S.; Butryn, M.; Wadden, T.A.; Fabricatore, A.; Nguyen, A.M.; Heymsfield, S. B. Evidence for prospective associations among depression and obesity in population-based studies. Obes. Rev., 2011, 12, e438-e453.
    • (2011) Obes. Rev. , vol.12 , pp. e438-e453
    • Faith, M.S.1    Butryn, M.2    Wadden, T.A.3    Fabricatore, A.4    Nguyen, A.M.5    Heymsfield, S.B.6
  • 78
    • 20044395965 scopus 로고    scopus 로고
    • Stress and the brain: From adaptation to disease
    • De Kloet, E.R.; Joels, M.; Holsboer, F. Stress and the brain: from adaptation to disease. Nat. Rev. Neurosci., 2005, 6, 463-475.
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 463-475
    • De Kloet, E.R.1    Joels, M.2    Holsboer, F.3
  • 79
    • 0033797445 scopus 로고    scopus 로고
    • The corticosteroid receptor hypothesis of depression
    • Holsboer, F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology, 2000, 23, 477-501.
    • (2000) Neuropsychopharmacology , vol.23 , pp. 477-501
    • Holsboer, F.1
  • 80
    • 0027049491 scopus 로고
    • Increased glucocorticoid receptor gene promoter activity after antidepressant treatment
    • Pepin, M.C.; Govindan, M.V.; Barden, N. Increased glucocorticoid receptor gene promoter activity after antidepressant treatment. Mol. Pharmacol., 1992, 41, 1016-1022.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 1016-1022
    • Pepin, M.C.1    Govindan, M.V.2    Barden, N.3
  • 81
    • 0026543152 scopus 로고
    • Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene
    • Pepin, M.C.; Pothier, F.; Barden, N. Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene. Nature, 1992, 355, 725-728.
    • (1992) Nature , vol.355 , pp. 725-728
    • Pepin, M.C.1    Pothier, F.2    Barden, N.3
  • 84
    • 0034460335 scopus 로고    scopus 로고
    • Mice with an Increased Glucocorticoid Receptor Gene Dosage Show Enhanced Resistance to Stress and Endotoxic Shock 1096
    • Reichardt, H.M.; Umland, T.; Bauer, A.; Kretz, O.; Schutz, G. Mice with an Increased Glucocorticoid Receptor Gene Dosage Show Enhanced Resistance to Stress and Endotoxic Shock 1096. Mol. Cell Biol., 2000, 20, 9009-9017.
    • Mol. Cell Biol. , vol.2000 , Issue.20 , pp. 9009-9017
    • Reichardt, H.M.1    Umland, T.2    Bauer, A.3    Kretz, O.4    Schutz, G.5
  • 86
    • 12244264438 scopus 로고    scopus 로고
    • Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior
    • Boyle, M.P.; Brewer, J.A.; Funatsu, M.; Wozniak, D.F.; Tsien, J. Z.; Izumi, Y.; Muglia, L.J. Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior. Proc. Natl. Acad Sci. USA, 2005, 102, 473-478.
    • (2005) Proc. Natl. Acad Sci. USA , vol.102 , pp. 473-478
    • Boyle, M.P.1    Brewer, J.A.2    Funatsu, M.3    Wozniak, D.F.4    Tsien, J.Z.5    Izumi, Y.6    Muglia, L.J.7
  • 90
    • 84905851457 scopus 로고    scopus 로고
    • Placental FKBP5 genetic and epigenetic variation is associated with infant neurobehavioral outcomes in the RICHS cohort
    • e104913
    • Paquette, A.G.; Lester, B.M.; Koestler, D.C.; Lesseur, C.; Armstrong, D.A.; Marsit, C.J. Placental FKBP5 genetic and epigenetic variation is associated with infant neurobehavioral outcomes in the RICHS cohort. PLoS One, 2014, 9, e104913.
    • (2014) Plos One , pp. 9
    • Paquette, A.G.1    Lester, B.M.2    Koestler, D.C.3    Lesseur, C.4    Armstrong, D.A.5    Marsit, C.J.6
  • 92
    • 84895895423 scopus 로고    scopus 로고
    • Effect of the common functional FKBP5 variant (Rs1360780) on the hypothalamicpituitary-adrenal axis and peripheral blood gene expression
    • Fujii, T.; Hori, H.; Ota, M.; Hattori, K.; Teraishi, T.; Sasayama, D.; Yamamoto, N.; Higuchi, T.; Kunugi, H. Effect of the common functional FKBP5 variant (rs1360780) on the hypothalamicpituitary-adrenal axis and peripheral blood gene expression. Psychoneuroendocrinology, 2014, 42, 89-97.
    • (2014) Psychoneuroendocrinology , vol.42 , pp. 89-97
    • Fujii, T.1    Hori, H.2    Ota, M.3    Hattori, K.4    Teraishi, T.5    Sasayama, D.6    Yamamoto, N.7    Higuchi, T.8    Kunugi, H.9
  • 94
    • 84879327418 scopus 로고    scopus 로고
    • Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults
    • Mahon, P.B.; Zandi, P.P.; Potash, J.B.; Nestadt, G.; Wand, G.S. Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults. Psychopharmacology (Berl), 2013, 227, 231-241.
    • (2013) Psychopharmacology (Berl) , vol.227 , pp. 231-241
    • Mahon, P.B.1    Zandi, P.P.2    Potash, J.B.3    Nestadt, G.4    Wand, G.S.5
  • 95
    • 77957864852 scopus 로고    scopus 로고
    • Association study between a functional polymorphism of FK506-binding protein 51 (FKBP5) gene and personality traits in healthy subjects
    • Shibuya, N.; Suzuki, A.; Sadahiro, R.; Kamata, M.; Matsumoto, Y.; Goto, K.; Hozumi, Y.; Otani, K. Association study between a functional polymorphism of FK506-binding protein 51 (FKBP5) gene and personality traits in healthy subjects. Neurosci. Lett., 2010, 485, 194-197.
    • (2010) Neurosci. Lett. , vol.485 , pp. 194-197
    • Shibuya, N.1    Suzuki, A.2    Sadahiro, R.3    Kamata, M.4    Matsumoto, Y.5    Goto, K.6    Hozumi, Y.7    Otani, K.8
  • 98
    • 84912530370 scopus 로고    scopus 로고
    • Association between the common functional FKBP5 variant (Rs1360780) and brain structure in a nonclinical population
    • Fujii, T.; Ota, M.; Hori, H.; Hattori, K.; Teraishi, T.; Sasayama, D.; Higuchi, T.; Kunugi, H. Association between the common functional FKBP5 variant (rs1360780) and brain structure in a nonclinical population. J. Psychiatr. Res., 2014, 58, 96-101.
    • (2014) J. Psychiatr. Res. , vol.58 , pp. 96-101
    • Fujii, T.1    Ota, M.2    Hori, H.3    Hattori, K.4    Teraishi, T.5    Sasayama, D.6    Higuchi, T.7    Kunugi, H.8
  • 99
    • 84887223481 scopus 로고    scopus 로고
    • Association among clinical response, hippocampal volume, and FKBP5 gene expression in individuals with posttraumatic stress disorder receiving cognitive behavioral therapy
    • Levy-Gigi, E.; Szabó, C.; Kelemen, O.; Kéri, S. Association among clinical response, hippocampal volume, and FKBP5 gene expression in individuals with posttraumatic stress disorder receiving cognitive behavioral therapy. Biol. Psychiatry, 2013, 74, 793-800.
    • (2013) Biol. Psychiatry , vol.74 , pp. 793-800
    • Levy-Gigi, E.1    Szabó, C.2    Kelemen, O.3    Kéri, S.4
  • 103
    • 77953611084 scopus 로고    scopus 로고
    • Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide
    • Roy, A.; Gorodetsky, E.; Yuan, Q.; Goldman, D.; Enoch, M.A. Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide. Neuropsychopharmacology, 2010, 35, 1674-1683.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1674-1683
    • Roy, A.1    Gorodetsky, E.2    Yuan, Q.3    Goldman, D.4    Enoch, M.A.5
  • 105
    • 84883543539 scopus 로고    scopus 로고
    • Endocrine aspects of post-traumatic stress disorder and implications for diagnosis and treatment. Endocrinol. Metab. Clin
    • Daskalakis, N.P.; Lehrner, A.; Yehuda, R. Endocrine aspects of post-traumatic stress disorder and implications for diagnosis and treatment. Endocrinol. Metab. Clin. North Am., 2013, 42, 503-513.
    • (2013) North Am. , vol.42 , pp. 503-513
    • Daskalakis, N.P.1    Lehrner, A.2    Yehuda, R.3
  • 107
    • 84856005896 scopus 로고    scopus 로고
    • Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: A prospective study. Biol
    • van Zuiden, M.; Geuze, E.; Willemen, H.L.; Vermetten, E.; Maas, M.; Amarouchi, K.; Kavelaars, A.; Heijnen, C.J. Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: a prospective study. Biol. Psychiatry, 2012, 71, 309-316.
    • (2012) Psychiatry , vol.71 , pp. 309-316
    • Van Zuiden, M.1    Geuze, E.2    Willemen, H.L.3    Vermetten, E.4    Maas, M.5    Amarouchi, K.6    Kavelaars, A.7    Heijnen, C.J.8
  • 108
    • 18444386162 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors 2508
    • 500-13
    • Segman, R.H.; Shefi, N.; Goltser-Dubner, T.; Friedman, N.; Kaminski, N.; Shalev, A.Y. Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors 2508. Mol. Psychiatry, 2005, 10, 500-13, 425.
    • (2005) Mol. Psychiatry , Issue.425 , pp. 10
    • Segman, R.H.1    Shefi, N.2    Goltser-Dubner, T.3    Friedman, N.4    Kaminski, N.5    Shalev, A.Y.6
  • 109
    • 84899121900 scopus 로고    scopus 로고
    • Changes in FKBP5 expression and memory functions during cognitive-behavioral therapy in posttraumatic stress disorder: A preliminary study
    • Szabó, C.; Kelemen, O.; Keri, S. Changes in FKBP5 expression and memory functions during cognitive-behavioral therapy in posttraumatic stress disorder: a preliminary study. Neurosci. Lett., 2014, 569, 116-120.
    • (2014) Neurosci. Lett. , vol.569 , pp. 116-120
    • Szabó, C.1    Kelemen, O.2    Keri, S.3
  • 110
    • 84930476498 scopus 로고    scopus 로고
    • Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: Implications for neuropsychiatric research and treatment.
    • Boscarino, J.A.; Erlich, P.M.; Hoffman, S.N.; Zhang, X. Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment. Neuropsychiatr. Dis. Treat., 2012, 8, 131-139.
    • (2012) Neuropsychiatr. Dis. Treat. , vol.8 , pp. 131-139
    • Boscarino, J.A.1    Erlich, P.M.2    Hoffman, S.N.3    Zhang, X.4
  • 111
    • 79955994712 scopus 로고    scopus 로고
    • Association of FKBP5, COMT and CHRNA5 polymorphisms with PTSD among outpatients at risk for PTSD
    • Boscarino, J.A.; Erlich, P.M.; Hoffman, S.N.; Rukstalis, M.; Stewart, W.F. Association of FKBP5, COMT and CHRNA5 polymorphisms with PTSD among outpatients at risk for PTSD. Psychiatry Res., 2011, 188, 173-174.
    • (2011) Psychiatry Res. , vol.188 , pp. 173-174
    • Boscarino, J.A.1    Erlich, P.M.2    Hoffman, S.N.3    Rukstalis, M.4    Stewart, W.F.5
  • 112
    • 84876206077 scopus 로고    scopus 로고
    • Predicting PTSD using the New York Risk Score with genotype data: Potential clinical and research opportunities
    • Boscarino, J. A.; Kirchner, H. L.; Hoffman, S. N.; Erlich, P. M. Predicting PTSD using the New York Risk Score with genotype data: potential clinical and research opportunities. Neuropsychiatr. Dis. Treat., 2013, 9, 517-527.
    • (2013) Neuropsychiatr. Dis. Treat. , vol.9 , pp. 517-527
    • Boscarino, J.A.1    Kirchner, H.L.2    Hoffman, S.N.3    Erlich, P.M.4
  • 113
    • 84922663029 scopus 로고    scopus 로고
    • Searching for non-genetic molecular and imaging PTSD risk and resilience markers: Systematic review of literature and design of the German Armed Forces PTSD biomarker study
    • Schmidt, U.; Willmund, G.D.; Holsboer, F.; Wotjak, C.T.; Gallinat, J.; Kowalski, J.T.; Zimmermann, P. Searching for non-genetic molecular and imaging PTSD risk and resilience markers: Systematic review of literature and design of the German Armed Forces PTSD biomarker study. Psychoneuroendocrinology, 2014
    • (2014) Psychoneuroendocrinology
    • Schmidt, U.1    Willmund, G.D.2    Holsboer, F.3    Wotjak, C.T.4    Gallinat, J.5    Kowalski, J.T.6    Zimmermann, P.7
  • 120
    • 80054814012 scopus 로고    scopus 로고
    • Interaction of variants in the FKBP5 gene and adverse life events in predicting the first depression onset: Results from a ten-year prospective community study
    • Zimmermann, P.; Brückl, T.; Nocon, A.; Pfister, H.; Binder, E. B.; Uhr, M.; Lieb, R.; Moffitt, T.E.; Caspi, A.; Holsboer, F.; Ising, M. Interaction of variants in the FKBP5 gene and adverse life events in predicting the first depression onset: results from a ten-year prospective community study. Am. J. Psychiatry, 2011, 168, 1107-1116.
    • (2011) Am. J. Psychiatry , vol.168 , pp. 1107-1116
    • Zimmermann, P.1    Brückl, T.2    Nocon, A.3    Pfister, H.4    Binder, E.B.5    Uhr, M.6    Lieb, R.7    Moffitt, T.E.8    Caspi, A.9    Holsboer, F.10    Ising, M.11
  • 121
    • 77955550908 scopus 로고    scopus 로고
    • Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort
    • Lavebratt, C.; Aberg, E.; Sjoholm, L.K.; Forsell, Y. Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort. J. Affect. Disord.. 2010, 125, 249-255.
    • (2010) J. Affect. Disord.. , vol.125 , pp. 249-255
    • Lavebratt, C.1    Aberg, E.2    Sjoholm, L.K.3    Forsell, Y.4
  • 124
  • 127
    • 84904767251 scopus 로고    scopus 로고
    • Relationship of the FKBP5 C/T polymorphism with dysfunctional attitudes predisposing to depression
    • Suzuki, A.; Matsumoto, Y.; Sadahiro, R.; Enokido, M.; Goto, K.; Otani, K. Relationship of the FKBP5 C/T polymorphism with dysfunctional attitudes predisposing to depression. Compr. Psychiatry, 2014, 55, 1422-1425.
    • (2014) Compr. Psychiatry , vol.55 , pp. 1422-1425
    • Suzuki, A.1    Matsumoto, Y.2    Sadahiro, R.3    Enokido, M.4    Goto, K.5    Otani, K.6
  • 128
    • 84979456390 scopus 로고    scopus 로고
    • Accumulation of Cytoplasmic Glucocorticoid Receptor Is Related to Elevation of FKBP5 in Lymphocytes of Depressed Patients
    • Lukic, I.; Mitic, M.; Soldatovic, I.; Jovicic, M.; Maric, N.; Radulovic, J.; Adzic, M. Accumulation of Cytoplasmic Glucocorticoid Receptor Is Related to Elevation of FKBP5 in Lymphocytes of Depressed Patients. J. Mol. Neurosci., 2014.
    • (2014) J. Mol. Neurosci
    • Lukic, I.1    Mitic, M.2    Soldatovic, I.3    Jovicic, M.4    Maric, N.5    Radulovic, J.6    Adzic, M.7
  • 131
    • 84864772058 scopus 로고    scopus 로고
    • FKBP5 polymorphisms as vulnerability to anxiety and depression in patients with advanced gastric cancer: A controlled and prospective study
    • Kang, J. I.; Chung, H. C.; Jeung, H. C.; Kim, S. J.; An, S. K.; Namkoong, K. (2012). FKBP5 polymorphisms as vulnerability to anxiety and depression in patients with advanced gastric cancer: a controlled and prospective study. Psychoneuroendocrinology, 37, 1569-1576.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 1569-1576
    • Kang, J.I.1    Chung, H.C.2    Jeung, H.C.3    Kim, S.J.4    An, S.K.5    Namkoong, K.6
  • 133
    • 84859242300 scopus 로고    scopus 로고
    • Regulation of mRNA expression encoding chaperone and co-chaperone proteins of the glucocorticoid receptor in peripheral blood: Association with depressive symptoms during pregnancy. Psychol
    • Katz, E.R.; Stowe, Z.N.; Newport, D.J.; Kelley, M.E.; Pace, T.W.; Cubells, J.F.; Binder, E.B. Regulation of mRNA expression encoding chaperone and co-chaperone proteins of the glucocorticoid receptor in peripheral blood: association with depressive symptoms during pregnancy. Psychol. Med., 2012, 42, 943-956.
    • (2012) Med. , vol.42 , pp. 943-956
    • Katz, E.R.1    Stowe, Z.N.2    Newport, D.J.3    Kelley, M.E.4    Pace, T.W.5    Cubells, J.F.6    Binder, E.B.7
  • 138
    • 70350787070 scopus 로고    scopus 로고
    • Pharmacogenetics studies in STAR*D: Strengths, limitations, and results. Psychiatr
    • Laje, G.; Perlis, R.H.; Rush, A.J.; McMahon, F.J. Pharmacogenetics studies in STAR*D: strengths, limitations, and results. Psychiatr. Serv., 2009, 60, 1446-1457.
    • (2009) Serv. , vol.60 , pp. 1446-1457
    • Laje, G.1    Perlis, R.H.2    Rush, A.J.3    McMahon, F.J.4
  • 139
    • 78650621274 scopus 로고    scopus 로고
    • Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders
    • Zou, Y.F.; Wang, F.; Feng, X.L.; Li, W.F.; Tao, J.H.; Pan, F.M.; Huang, F.; Su, H. Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders. Neurosci. Lett., 2010, 484, 56-61.
    • (2010) Neurosci. Lett. , vol.484 , pp. 56-61
    • Zou, Y.F.1    Wang, F.2    Feng, X.L.3    Li, W.F.4    Tao, J.H.5    Pan, F.M.6    Huang, F.7    Su, H.8
  • 142
    • 35748958398 scopus 로고    scopus 로고
    • Genetic variability at HPA axis in major depression and clinical response to antidepressant treatment.
    • Papiol, S.; Arias, B.; Gastó, C.; Gutiérrez, B.; Catalán, R.; Fañanás, L. Genetic variability at HPA axis in major depression and clinical response to antidepressant treatment. J. Affect. Disord., 2007, 104, 83-90.
    • (2007) J. Affect. Disord. , vol.104 , pp. 83-90
    • Papiol, S.1    Arias, B.2    Gastó, C.3    Gutiérrez, B.4    Catalán, R.5    Fañanás, L.6
  • 144
    • 36749007930 scopus 로고    scopus 로고
    • Lack of supporting evidence for a genetic association of the FKBP5 polymorphism and response to antidepressant treatment 26
    • Tsai, S.J.; Hong, C.J.; Chen, T.J.; Yu, Y.W. Lack of supporting evidence for a genetic association of the FKBP5 polymorphism and response to antidepressant treatment 26. Am. J. Med. Genet. B. Neuropsychiatr. Genet., 2007, 144B, 1097-1098.
    • (2007) Am. J. Med. Genet. B. Neuropsychiatr. Genet. , vol.144 , pp. 1097-1098
    • Tsai, S.J.1    Hong, C.J.2    Chen, T.J.3    Yu, Y.W.4
  • 147
    • 84893623213 scopus 로고    scopus 로고
    • Possible association between haplotypes of the FKBP5 gene and suicidal bipolar disorder, but not with melancholic depression and psychotic features, in the course of bipolar disorder
    • Leszczyñska-Rodziewicz, A.; Szczepankiewicz, A.; Narozna, B.; Skibiñska, M.; Pawlak, J.; Dmitrzak-Weglarz, M.; Hauser, J. Possible association between haplotypes of the FKBP5 gene and suicidal bipolar disorder, but not with melancholic depression and psychotic features, in the course of bipolar disorder. Neuropsychiatr. Dis. Treat., 2014, 10, 243-248.
    • (2014) Neuropsychiatr. Dis. Treat. , vol.10 , pp. 243-248
    • Leszczyñska-Rodziewicz, A.1    Szczepankiewicz, A.2    Narozna, B.3    Skibiñska, M.4    Pawlak, J.5    Dmitrzak-Weglarz, M.6    Hauser, J.7
  • 149
    • 0038136898 scopus 로고    scopus 로고
    • Essential role of the unusual DNA binding motif of BAG-1 for inhibition of the glucocorticoid receptor
    • Schmidt, U.; Wochnik, G.M.; Rosenhagen, M.C.; Young, J.C.; Hartl, F.U.; Rein, T. Essential role of the unusual DNA binding motif of BAG-1 for inhibition of the glucocorticoid receptor. J. Biol.l Chem., 2003, 278, 4926-4931.
    • (2003) J. Biol.L Chem. , vol.278 , pp. 4926-4931
    • Schmidt, U.1    Wochnik, G.M.2    Rosenhagen, M.C.3    Young, J.C.4    Hartl, F.U.5    Rein, T.6
  • 150
    • 58049191498 scopus 로고    scopus 로고
    • Role of the hsp70 cochaperone BAG1 in glucocorticoid receptor function and stress-related diseases
    • Schmidt, U.; Holsboer, F.; Rein, T. Role of the hsp70 cochaperone BAG1 in glucocorticoid receptor function and stress-related diseases. Proc. Natl. Acad. Sci.USA, 2008, 105, E101.
    • (2008) Proc. Natl. Acad. Sci.Usa , vol.105 , pp. 101
    • Schmidt, U.1    Holsboer, F.2    Rein, T.3
  • 151
    • 84896809401 scopus 로고    scopus 로고
    • Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness
    • Sinclair, D.; Fillman, S.G.; Webster, M.J.; Weickert, C.S. Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness. Sci. Rep., 2013, 3, 3539.
    • (2013) Sci. Rep. , vol.3 , pp. 3539
    • Sinclair, D.1    Fillman, S.G.2    Webster, M.J.3    Weickert, C.S.4
  • 156
    • 0035354559 scopus 로고    scopus 로고
    • Developmental changes in cortisol secretion in normal and at-risk youth
    • Walker, E.F.; Walder, D.J.; Reynolds, F. Developmental changes in cortisol secretion in normal and at-risk youth. Dev. Psychopathol, 2001, 13, 721-732.
    • (2001) Dev. Psychopathol , vol.13 , pp. 721-732
    • Walker, E.F.1    Walder, D.J.2    Reynolds, F.3
  • 158
    • 84902657378 scopus 로고    scopus 로고
    • Drug addiction and stress-response genetic variability: Association study in African Americans
    • Levran, O.; Randesi, M.; Li, Y.; Rotrosen, J.; Ott, J.; Adelson, M.; Kreek, M.J. Drug addiction and stress-response genetic variability: association study in African Americans. Ann. Hum. Genet., 2014, 78, 290-298.
    • (2014) Ann. Hum. Genet. , vol.78 , pp. 290-298
    • Levran, O.1    Randesi, M.2    Li, Y.3    Rotrosen, J.4    Ott, J.5    Adelson, M.6    Kreek, M.J.7
  • 159
    • 46149120544 scopus 로고    scopus 로고
    • A role for brain stress systems in addiction
    • Koob, G.F. A role for brain stress systems in addiction. Neuron, 2008, 59, 11-34.
    • (2008) Neuron , vol.59 , pp. 11-34
    • Koob, G.F.1
  • 162
    • 33845724030 scopus 로고    scopus 로고
    • Review of prospective studies of biologic predictors of suicidal behavior in mood disorders
    • Mann, J.J. Currier, D. A review of prospective studies of biologic predictors of suicidal behavior in mood disorders. Arch. Suicide Res., 2007, 11, 3-16.
    • (2007) Arch. Suicide Res. , vol.11 , pp. 3-16
    • Mann, J.J.1    Currier, D.A.2
  • 163
  • 165
    • 77952893653 scopus 로고    scopus 로고
    • Pharmacogenomics of suicidal events
    • Brent, D.; Melhem, N.; Turecki, G. Pharmacogenomics of suicidal events. Pharmacogenomics, 2010, 11, 793-807.
    • (2010) Pharmacogenomics , vol.11 , pp. 793-807
    • Brent, D.1    Melhem, N.2    Turecki, G.3
  • 166
    • 84883769810 scopus 로고    scopus 로고
    • Glucocorticoid receptor signaling in health and disease
    • Kadmiel, M., Cidlowski, J.A. Glucocorticoid receptor signaling in health and disease. Trends Pharmacol. Sci., 2013, 34, 518-530.
    • (2013) Trends Pharmacol. Sci. , vol.34 , pp. 518-530
    • Kadmiel, M.1    Cidlowski, J.A.2
  • 169
    • 77949519241 scopus 로고    scopus 로고
    • Enhanced expression of mRNA for FK506-binding protein 5 in bone marrow CD34 positive cells in patients with rheumatoid arthritis
    • Matsushita, R.; Hashimoto, A.; Tomita, T.; Yoshitawa, H.; Tanaka, S.; Endo, H.; Hirohata, S. Enhanced expression of mRNA for FK506-binding protein 5 in bone marrow CD34 positive cells in patients with rheumatoid arthritis. Clin. Exp. Rheumatol., 2010, 28, 87-90.
    • (2010) Clin. Exp. Rheumatol. , vol.28 , pp. 87-90
    • Matsushita, R.1    Hashimoto, A.2    Tomita, T.3    Yoshitawa, H.4    Tanaka, S.5    Endo, H.6    Hirohata, S.7
  • 170
    • 40349098670 scopus 로고    scopus 로고
    • FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway
    • Jiang, W.; Cazacu, S.; Xiang, C.; Zenklusen, J.C.; Fine, H.A.; Berens, M.; Armstrong, B.; Brodie, C.; Mikkelsen, T. FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway. Neoplasia., 2008, 10, 235-243.
    • (2008) Neoplasia. , vol.10 , pp. 235-243
    • Jiang, W.1    Cazacu, S.2    Xiang, C.3    Zenklusen, J.C.4    Fine, H.A.5    Berens, M.6    Armstrong, B.7    Brodie, C.8    Mikkelsen, T.9
  • 172
    • 79958694525 scopus 로고    scopus 로고
    • A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling
    • Cotta-Ramusino, C.; McDonald, E.R.;Hurov, K.; Sowa, M.E.; Harper, J.W.; Elledge, S.J. A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. Science, 2011, 332, 1313-1317.
    • (2011) Science , vol.332 , pp. 1313-1317
    • Cotta-Ramusino, C.1    McDonald, E.R.2    Hurov, K.3    Sowa, M.E.4    Harper, J.W.5    Elledge, S.J.6
  • 174
    • 0032467785 scopus 로고    scopus 로고
    • Brain corticosteroid receptor balance in health and disease
    • De Kloet, E. R.; Vreugdenhil, E.; Oitzl, M. S.; Joels, M. (1998). Brain corticosteroid receptor balance in health and disease. Endocr. Rev., 1998, 19, 269-301.
    • (1998) Endocr. Rev. , vol.1998 , Issue.19 , pp. 269-301
    • De Kloet, E.R.1    Vreugdenhil, E.2    Oitzl, M.S.3    Joels, M.4
  • 178
    • 84891862344 scopus 로고    scopus 로고
    • A heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing the heat shock response
    • McConnell, J.R.; Alexander, L.A.; McAlpine, S.R. (2014). A heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing the heat shock response. Bioorg. Med. Chem. Lett., 2014, 24, 661-666.
    • (2014) Bioorg. Med. Chem. Lett. , vol.2014 , Issue.24 , pp. 661-666
    • McConnell, J.R.1    Alexander, L.A.2    McAlpine, S.R.3
  • 179
    • 84891633163 scopus 로고    scopus 로고
    • Gene-environment interactions at the FKBP5 locus: Sensitive periods, mechanisms and pleiotropism
    • Zannas, A.S. Binder, E.B. Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism. Genes Brain Behav., 2014, 13, 25-37.
    • (2014) Genes Brain Behav. , vol.13 , pp. 25-37
    • Zannas, A.S.1    Binder, E.B.2
  • 181
    • 59849098177 scopus 로고    scopus 로고
    • Targeted ablation reveals a novel role of FKBP52 in gene-specific regulation of glucocorticoid receptor transcriptional activity
    • Wolf, I.M.; Periyasamy, S.; Hinds, T.; Jr.; Yong, W.; Shou, W.; Sanchez, E.R. (2009). Targeted ablation reveals a novel role of FKBP52 in gene-specific regulation of glucocorticoid receptor transcriptional activity. J. Steroid Biochem. Mol. Biol., 2009, 113, 36-45.
    • (2009) J. Steroid Biochem. Mol. Biol. , vol.2009 , Issue.113 , pp. 36-45
    • Wolf, I.M.1    Periyasamy, S.2    Hinds, T.3    Yong, W.4    Shou, W.5    Sanchez, E.R.6
  • 182
    • 0034629150 scopus 로고    scopus 로고
    • The Hsp Organizer Protein Hop Enhances the Rate of but Is Not Essential for Glucocorticoid Receptor Folding by the Multiprotein Hsp90-based Chaperone System
    • Morishima, Y.; Kanelakis, K.C.; Silverstein, A.M.; Dittmar, K.D.; Estrada, L.; Pratt, W.B. The Hsp Organizer Protein Hop Enhances the Rate of but Is Not Essential for Glucocorticoid Receptor Folding by the Multiprotein Hsp90-based Chaperone System. J. Biol. Chem., 2000, 275, 6894-6900.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6894-6900
    • Morishima, Y.1    Kanelakis, K.C.2    Silverstein, A.M.3    Dittmar, K.D.4    Estrada, L.5    Pratt, W.B.6
  • 183
    • 0040370216 scopus 로고    scopus 로고
    • Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptormediated growth arrest
    • Zuo, Z.; Urban, G.; Scammell, J.G.; Dean, N.M.; McLean, T.K.; Aragon, I.; Honkanen, R.E. (1999). Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptormediated growth arrest. Biochemistry, 1999, 38, 8849-8857.
    • (1999) Biochemistry , vol.1999 , Issue.38 , pp. 8849-8857
    • Zuo, Z.1    Urban, G.2    Scammell, J.G.3    Dean, N.M.4    McLean, T.K.5    Aragon, I.6    Honkanen, R.E.7
  • 184
    • 33847198615 scopus 로고    scopus 로고
    • Modulation of glucocorticoid receptor phosphorylation and transcriptional activity by a C-terminal-associated protein phosphatase
    • Wang, Z.; Chen, W.; Kono, E.; Dang, T.; Garabedian, M.J. Modulation of glucocorticoid receptor phosphorylation and transcriptional activity by a C-terminal-associated protein phosphatase. Mol. Endocrinol., 2007, 21, 625-634.
    • (2007) Mol. Endocrinol. , vol.21 , pp. 625-634
    • Wang, Z.1    Chen, W.2    Kono, E.3    Dang, T.4    Garabedian, M.J.5
  • 186
    • 0037119472 scopus 로고    scopus 로고
    • Activation function-1 domain of androgen receptor contributes to the interaction between subnuclear splicing factor compartment and nuclear receptor compartment. Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a coactivator for the receptor
    • Zhao, Y.; Goto, K.; Saitoh, M.; Yanase, T.; Nomura, M.; Okabe, T.; Takayanagi, R.; Nawata, H. Activation function-1 domain of androgen receptor contributes to the interaction between subnuclear splicing factor compartment and nuclear receptor compartment. Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a coactivator for the receptor. J. Biol.Chem., 2002, 277, 30031-30039.
    • (2002) J. Biol.Chem. , vol.277 , pp. 30031-30039
    • Zhao, Y.1    Goto, K.2    Saitoh, M.3    Yanase, T.4    Nomura, M.5    Okabe, T.6    Takayanagi, R.7    Nawata, H.8
  • 187
    • 0042815093 scopus 로고    scopus 로고
    • Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system
    • Brychzy, A.; Rein, T.; Winklhofer, K.F.; Hartl, F.U.; Young, J.C.; and Obermann, W.M. Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system. EMBO J., 2003, 22, 3613-3623.
    • (2003) EMBO J. , vol.22 , pp. 3613-3623
    • Brychzy, A.1    Rein, T.2    Winklhofer, K.F.3    Hartl, F.U.4    Young, J.C.5    Obermann, W.M.6


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