Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: Implications for neuropsychiatric research and treatment

Neuropsychiatric Disease and Treatment

Volumn 8, Issue , 2012, Pages 131-139

  Boscarino, Joseph A ^a,b   Erlich, Porat M ^a,b   Hoffman, Stuart N ^a   Zhang, Xiaopeng ^a  

^a GEISINGER MEDICAL CENTER   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Childhood adversity; Genetic association study; Neuroticism; Posttraumatic stress disorder; Risk alleles; Single nucleotide polymorphism; Trauma exposure

Indexed keywords

CATECHOL METHYLTRANSFERASE; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; DNA; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 5; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA5; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; BIVARIATE ANALYSIS; CHRNA5 GENE; COMT GENE; CRHR1 GENE; DEMOGRAPHY; DISEASE ASSOCIATION; DNA DETERMINATION; FEMALE; FKBP5 GENE; GENE; GENE LOCUS; GENETIC POLYMORPHISM; HUMAN; INTERVIEW; LIFESPAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RESEARCH; MENTAL HEALTH CARE; MENTAL STRESS; NEUROSIS; PERSONALITY; POSTTRAUMATIC STRESS DISORDER; PSYCHOTRAUMA; RISK ASSESSMENT; SELF ESTEEM; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84930476498     PISSN: 11766328     EISSN: 11782021     Source Type: Journal    
DOI: 10.2147/NDT.S29508     Document Type: Article

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