Allele-specific epigenetic modification: A molecular mechanism for gene-environment interactions in stress-related psychiatric disorders?

Epigenomics

Volumn 5, Issue 2, 2013, Pages 109-112

  Klengel, Torsten ^a   Binder, Elisabeth B ^a,b  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

chromatin conformation; demethylation; DNA methylation; gene environment interaction; plasticity allele; PTSD

Indexed keywords

FK 506 BINDING PROTEIN; GLUCOCORTICOID RECEPTOR; RNA POLYMERASE II; TATA BINDING PROTEIN;

ALLELE; ANXIETY DISORDER; DISEASE PREDISPOSITION; DNA METHYLATION; DNA MODIFICATION; ENHANCER REGION; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT; EPIGENETICS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; HISTONE MODIFICATION; HUMAN; LIGAND BINDING; MAJOR DEPRESSION; MENTAL DISEASE; MENTAL STRESS; MOLECULAR GENETICS; NEGATIVE FEEDBACK; PHENOTYPE; PHENOTYPIC PLASTICITY; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; REVIEW;

ALLELES; CHROMATIN; DNA METHYLATION; EPIGENESIS, GENETIC; GENE-ENVIRONMENT INTERACTION; HUMANS; STRESS DISORDERS, POST-TRAUMATIC; STRESS, PSYCHOLOGICAL;

EID: 84876140223     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.13.11     Document Type: Review

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