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Volumn 6, Issue 6, 2005, Pages 463-475

Stress and the brain: From adaptation to disease

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CORTICOSTEROID; NEUROPEPTIDE; TRANSCRIPTION FACTOR;

EID: 20044395965     PISSN: 1471003X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrn1683     Document Type: Review
Times cited : (3673)

References (166)
  • 1
    • 34249007019 scopus 로고
    • Syndrome produced by diverse nocuous agents
    • Selye, H. Syndrome produced by diverse nocuous agents. Nature 138, 32 (1936).
    • (1936) Nature , vol.138 , pp. 32
    • Selye, H.1
  • 2
    • 0004276621 scopus 로고
    • (eds Brown, M. R. & Koob, G. F.) (Rivier Marcel Dekker, Inc., New York
    • Levine, S. & Ursin, H. in Stress Neurobiology and Neuroendocrinology (eds Brown, M. R. & Koob, G. F.) 3-21 (Rivier Marcel Dekker, Inc., New York. 1991).
    • (1991) Stress Neurobiology and Neuroendocrinology , pp. 3-21
    • Levine, S.1    Ursin, H.2
  • 3
    • 0026536665 scopus 로고
    • The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis
    • Chrousos, G. P. & Gold, P. W. The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis. JAMA 267, 1244-1252 (1992).
    • (1992) JAMA , vol.267 , pp. 1244-1252
    • Chrousos, G.P.1    Gold, P.W.2
  • 4
    • 0032467785 scopus 로고    scopus 로고
    • Brain corticosteroid receptor balance in health and disease
    • De Kloet, E. R., Vreugdenhil, E., Oitzl, M. S. & Joëls, M. Brain corticosteroid receptor balance in health and disease. Endocr. Rev. 19, 269-301 (1998)
    • (1998) Endocr. Rev. , vol.19 , pp. 269-301
    • De Kloet, E.R.1    Vreugdenhil, E.2    Oitzl, M.S.3    Joëls, M.4
  • 5
    • 0000980089 scopus 로고    scopus 로고
    • (ed. Fink, G.) (Academic, San Diego, USA)
    • McEwen, B. in Encyclopedia of Stress Vol. 3 (ed. Fink, G.) 508-509 (Academic, San Diego, USA, 2000).
    • (2000) Encyclopedia of Stress , vol.3 , pp. 508-509
    • McEwen, B.1
  • 6
    • 0034454682 scopus 로고    scopus 로고
    • How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
    • Sapolsky, R. M., Romero, L. M. & Munck, A. U. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocr. Rev. 21, 55-89 (2000).
    • (2000) Endocr. Rev. , vol.21 , pp. 55-89
    • Sapolsky, R.M.1    Romero, L.M.2    Munck, A.U.3
  • 8
    • 0141832631 scopus 로고    scopus 로고
    • Mood disorders and allostatic load
    • McEwen, B. S. Mood disorders and allostatic load. Biol. Psychiatry 54, 200-207 (2003).
    • (2003) Biol. Psychiatry , vol.54 , pp. 200-207
    • McEwen, B.S.1
  • 9
    • 0033797445 scopus 로고    scopus 로고
    • The corticosteroid receptor hypothesis of depression
    • Holsboer, F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 23, 477-501 (2000).
    • (2000) Neuropsychopharmacology , vol.23 , pp. 477-501
    • Holsboer, F.1
  • 11
    • 0037050366 scopus 로고    scopus 로고
    • Post-traumatic stress disorder
    • Yehuda, R. Post-traumatic stress disorder. N. Engl. J. Med. 346, 108-114 (2002).
    • (2002) N. Engl. J. Med. , vol.346 , pp. 108-114
    • Yehuda, R.1
  • 12
    • 0022383620 scopus 로고
    • Two receptor systems for corticosterone in rat brain: Microdistribution and differential occupation
    • Reul, J. M. & de Kloet, E. R. Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology 117, 2505-2511 (1985). The first account of two distinct nuclear receptor systems that bind naturally occurring glucocorticoids with a tenfold difference in affinity.
    • (1985) Endocrinology , vol.117 , pp. 2505-2511
    • Reul, J.M.1    De Kloet, E.R.2
  • 13
    • 0024109575 scopus 로고
    • The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response
    • Arriza, J. L., Simerty, R. B., Swanson, L. W. & Evans, R. M. The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response. Neuron 1, 887-900 (1988).
    • (1988) Neuron , vol.1 , pp. 887-900
    • Arriza, J.L.1    Simerty, R.B.2    Swanson, L.W.3    Evans, R.M.4
  • 14
    • 9644256061 scopus 로고    scopus 로고
    • Cortisol pulsatility and its role in stress regulation and health
    • Young, E. A., Abelson, J. & Lightman, S. L. Cortisol pulsatility and its role in stress regulation and health. Front Neuroendocrinol. 25, 69-76 (2004).
    • (2004) Front Neuroendocrinol. , vol.25 , pp. 69-76
    • Young, E.A.1    Abelson, J.2    Lightman, S.L.3
  • 15
    • 1842633512 scopus 로고    scopus 로고
    • Differences between brain structures in nuclear translocation and DNA binding of the glucocorticoid receptor during stress and the circadian cycle
    • Kitchener, P., Di Blasi, F., Borrelli, E, & Piazza, P. V. Differences between brain structures in nuclear translocation and DNA binding of the glucocorticoid receptor during stress and the circadian cycle. Eur. J. Neurosci. 19, 1837-1846 (2004).
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1837-1846
    • Kitchener, P.1    Di Blasi, F.2    Borrelli, E.3    Piazza, P.V.4
  • 16
    • 0037008871 scopus 로고    scopus 로고
    • GABAergic innervation of corticotropin-releasing hormone (CRH)-secreting parvocellular neurons and its plasticity as demonstrated by quantitative immunoelectron microscopy
    • Miklos, I. H. & Kovacs, K. J. GABAergic innervation of corticotropin-releasing hormone (CRH)-secreting parvocellular neurons and its plasticity as demonstrated by quantitative immunoelectron microscopy. Neuroscience 113, 581-592 (2002).
    • (2002) Neuroscience , vol.113 , pp. 581-592
    • Miklos, I.H.1    Kovacs, K.J.2
  • 17
    • 0242352373 scopus 로고    scopus 로고
    • Central mechanisms of stress integration; hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness
    • Herman, J. P. et al. Central mechanisms of stress integration; hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness. Front. Neuroendocrinol. 24, 151-180 (2003).
    • (2003) Front. Neuroendocrinol. , vol.24 , pp. 151-180
    • Herman, J.P.1
  • 18
    • 0034490754 scopus 로고    scopus 로고
    • Glucocorticoid and mineralocorticoid receptor mRNA expression in squirrel monkey brain
    • Patel, P. D. et al. Glucocorticoid and mineralocorticoid receptor mRNA expression in squirrel monkey brain. J. Psyciatr. Res. 34, 383-392 (2000).
    • (2000) J. Psyciatr. Res. , vol.34 , pp. 383-392
    • Patel, P.D.1
  • 19
    • 0028588118 scopus 로고
    • Heterodimerization between mineralocorticoid and glucocorticoid receptor: A new principle of glucocorticoid action in the CNS
    • Trapp, T., Rupprecht, R., Castren, M., Reul, J. M. & Holsboer, F. Heterodimerization between mineralocorticoid and glucocorticoid receptor: a new principle of glucocorticoid action in the CNS. Neuron 13, 1457-1462 (1994).
    • (1994) Neuron , vol.13 , pp. 1457-1462
    • Trapp, T.1    Rupprecht, R.2    Castren, M.3    Reul, J.M.4    Holsboer, F.5
  • 20
    • 0034973472 scopus 로고    scopus 로고
    • Dynamic changes in subcellular localization of mineralocorticoid receptor in living cells: In comparison with glucocorticoid receptor using dual-color labeling with green fluorescent protein spectral variants
    • Nishi, M., Ogawa, H., Ito, T., Matsuda, K. I. & Kawata, M. Dynamic changes in subcellular localization of mineralocorticoid receptor in living cells: in comparison with glucocorticoid receptor using dual-color labeling with green fluorescent protein spectral variants. Mol. Endocrinol. 15, 1077-1092 (2001).
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1077-1092
    • Nishi, M.1    Ogawa, H.2    Ito, T.3    Matsuda, K.I.4    Kawata, M.5
  • 21
    • 0035399665 scopus 로고    scopus 로고
    • Psychological stress increases hippocampal mineralocorticoid receptor levels: Involvement of corticotropin-releasing hormone
    • Gesing, A. et al. Psychological stress increases hippocampal mineralocorticoid receptor levels: involvement of corticotropin-releasing hormone. J. Neurosci. 21, 4B22-4B29 (2001).
    • (2001) J. Neurosci. , vol.21
    • Gesing, A.1
  • 22
    • 0036286318 scopus 로고    scopus 로고
    • Identification of corticosteroid-responsive genes in rat hippocampus using serial analysis of gene expression
    • Datson, N. A., van der Perk, J., deKloet, E. R. & Vreugdenhil, E. Identification of corticosteroid-responsive genes in rat hippocampus using serial analysis of gene expression. Eur. J. Neurosci. 14, 675-689 (2001). This paper describes a comprehensive database of MR- and GR-responsive gene patterns in the hippocampus.
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 675-689
    • Datson, N.A.1    Van Der Perk, J.2    DeKloet, E.R.3    Vreugdenhil, E.4
  • 23
    • 0035254186 scopus 로고    scopus 로고
    • Stress-triggered activation of gene expression in catechoiaminergic systems: Dynamics of transcriptional events
    • Sabban, E. L. & Kvetnansky, R. Stress-triggered activation of gene expression in catechoiaminergic systems: dynamics of transcriptional events. Trends Neurosci. 24, 91-98 (2001).
    • (2001) Trends Neurosci. , vol.24 , pp. 91-98
    • Sabban, E.L.1    Kvetnansky, R.2
  • 24
    • 0030956924 scopus 로고    scopus 로고
    • Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus
    • Schaaf, M. J., Hoetelmans, R. W., de Kloet, E. R. & Vreugdenhil, E. Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus. J. Neurosci. Res. 48, 334-341 (1997).
    • (1997) J. Neurosci. Res. , vol.48 , pp. 334-341
    • Schaaf, M.J.1    Hoetelmans, R.W.2    De Kloet, E.R.3    Vreugdenhil, E.4
  • 25
    • 0033816538 scopus 로고    scopus 로고
    • Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat
    • Hansson, A. C. et al. Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat. Eur. J. Neurosci. 12, 2918-2934 (2000).
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 2918-2934
    • Hansson, A.C.1
  • 26
    • 9944245000 scopus 로고    scopus 로고
    • Stress, cognitive impairment and cell adhesion molecules
    • Sandi, C. Stress, cognitive impairment and cell adhesion molecules. Nature Rev. Neurosci. 5, 917-930 (2004).
    • (2004) Nature Rev. Neurosci. , vol.5 , pp. 917-930
    • Sandi, C.1
  • 27
    • 1842556342 scopus 로고    scopus 로고
    • Bidirectional shift in the cornu ammonis 3 pyramidal dendritic organization following brief stress
    • Kole, M. H., Costoli, T., Koolhaas, J. M. & Fuchs, E. Bidirectional shift in the cornu ammonis 3 pyramidal dendritic organization following brief stress. Neuroscience 125, 337-347 (2004).
    • (2004) Neuroscience , vol.125 , pp. 337-347
    • Kole, M.H.1    Costoli, T.2    Koolhaas, J.M.3    Fuchs, E.4
  • 28
    • 0035842558 scopus 로고    scopus 로고
    • Morphological and functional properties of rat dentate granule cells after adrenalectomy
    • Wossink, J., Karst, H., Mayboroda, O. & Joëls, M. Morphological and functional properties of rat dentate granule cells after adrenalectomy. Neuroscience 108, 263-272 (2001).
    • (2001) Neuroscience , vol.108 , pp. 263-272
    • Wossink, J.1    Karst, H.2    Mayboroda, O.3    Joëls, M.4
  • 29
    • 13844299846 scopus 로고    scopus 로고
    • Age-dependent expression of glucocorticoid- and mineralocorticoid receptors on neural precursor cell populations in the adult murine hippocampus
    • Garcia, A., Steiner, B., Kronenberg, G., Bick-Sander, A. & Kempermann, G. Age-dependent expression of glucocorticoid- and mineralocorticoid receptors on neural precursor cell populations in the adult murine hippocampus. Aging Cell 3, 363-371 (2004).
    • (2004) Aging Cell , vol.3 , pp. 363-371
    • Garcia, A.1    Steiner, B.2    Kronenberg, G.3    Bick-Sander, A.4    Kempermann, G.5
  • 30
    • 0025909202 scopus 로고
    • Effects of aldosterone or RU28362 treatment on adrenalectomy-induced cell death in the dentate gyrus of the adult rat
    • Woolley, C. S., Gould, E., Sakai, R. R., Spencer, R. L. & McEwen, B. S. Effects of aldosterone or RU28362 treatment on adrenalectomy-induced cell death in the dentate gyrus of the adult rat. Brain Res. 554, 312-315 (1991).
    • (1991) Brain Res. , vol.554 , pp. 312-315
    • Woolley, C.S.1    Gould, E.2    Sakai, R.R.3    Spencer, R.L.4    McEwen, B.S.5
  • 31
    • 0030905258 scopus 로고    scopus 로고
    • The in vivo time course for elimination of adrenalectomy-induced apoptotic profiles from the granule cell layer of the rat hippocampus
    • Hu, Z., Yuri, K., Ozawa, H., Lu, H. & Kawata, M. The in vivo time course for elimination of adrenalectomy-induced apoptotic profiles from the granule cell layer of the rat hippocampus. J. Neurosci. 17, 3981-3989 (1997).
    • (1997) J. Neurosci. , vol.17 , pp. 3981-3989
    • Hu, Z.1    Yuri, K.2    Ozawa, H.3    Lu, H.4    Kawata, M.5
  • 32
    • 10944242626 scopus 로고    scopus 로고
    • Gene expression profiles associated with survival of individual rat dentate cells after endogenous corticosteroid deprivation
    • Nair, S. M. et al. Gene expression profiles associated with survival of individual rat dentate cells after endogenous corticosteroid deprivation. Eur. J. Neurosci. 20, 3233-3243 (2004).
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 3233-3243
    • Nair, S.M.1
  • 33
    • 0034117178 scopus 로고    scopus 로고
    • Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate
    • Almeida, O. F. et al. Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate. FASEB J. 14, 779-790 (2000).
    • (2000) FASEB J. , vol.14 , pp. 779-790
    • Almeida, O.F.1
  • 34
    • 0035801960 scopus 로고    scopus 로고
    • Exposure to fox odor inhibits cell proliferation in the hippocampus of adult rats via an adrenal hormone-dependent mechanism
    • Tanapat, P., Hastings, N. B., Rydel, T. A., Galea, L. A. & Gould, E. Exposure to fox odor inhibits cell proliferation in the hippocampus of adult rats via an adrenal hormone-dependent mechanism. J. Comp. Neurol. 437, 496-504 (2001). This report describes how stressful experiences rapidly diminish cell proliferation by increasing adrenal hormone levels, which results in a transient decrease in the number of adult-generated immature granule neurons.
    • (2001) J. Comp. Neurol. , vol.437 , pp. 496-504
    • Tanapat, P.1    Hastings, N.B.2    Rydel, T.A.3    Galea, L.A.4    Gould, E.5
  • 35
    • 0036275355 scopus 로고    scopus 로고
    • Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticoid receptor activation
    • Crochemore, C., Michaelidis, T. M., Fischer, D., Loeffler, J. P. & Almeida, O. F. Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticoid receptor activation. FASEB J. 16, 761-770 (2002).
    • (2002) FASEB J. , vol.16 , pp. 761-770
    • Crochemore, C.1    Michaelidis, T.M.2    Fischer, D.3    Loeffler, J.P.4    Almeida, O.F.5
  • 36
    • 1642499190 scopus 로고    scopus 로고
    • Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible
    • Heine, V. M., Maslam, S., Zareno, J., Joëls, M. & Lucassen, P. J. Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible. Eur. J. Neurosci 19, 131-144 (2004).
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 131-144
    • Heine, V.M.1    Maslam, S.2    Zareno, J.3    Joëls, M.4    Lucassen, P.J.5
  • 37
    • 0031030995 scopus 로고    scopus 로고
    • Steroid hormones and excitability in the mammalian brain
    • Joëls, M. Steroid hormones and excitability in the mammalian brain. Front. Neuroendocrinol. 18, 2-48 (1997).
    • (1997) Front. Neuroendocrinol. , vol.18 , pp. 2-48
    • Joëls, M.1
  • 38
    • 0024423920 scopus 로고
    • Effects of glucocorticoids and norepinephrine on the excitability in the hippocampus
    • Joëls, M. & de Kloet, E. R. Effects of glucocorticoids and norepinephrine on the excitability in the hippocampus. Science 245, 1502-1505 (1989). This paper shows that glucocorticoids can reduce transmitter-evoked excitability in the hippocampus, presumably through receptor-mediated genomic actions.
    • (1989) Science , vol.245 , pp. 1502-1505
    • Joëls, M.1    De Kloet, E.R.2
  • 39
    • 0026093654 scopus 로고
    • Mineralocorticoid hormones suppress serotonin-induced hyperpolarization of rat hippocampal CA1 neurons
    • Joëls, M., Hesen, W. & de Kloet, E. R. Mineralocorticoid hormones suppress serotonin-induced hyperpolarization of rat hippocampal CA1 neurons. J. Neurosci. 11, 2288-2294 (1991).
    • (1991) J. Neurosci. , vol.11 , pp. 2288-2294
    • Joëls, M.1    Hesen, W.2    De Kloet, E.R.3
  • 40
    • 0029671405 scopus 로고    scopus 로고
    • Corticosterone alters 5-HT1A receptor-mediated hyperpolarization in area CA1 hippocampal pyramidal neurons
    • Beck, S. G., Choi, K. C., List, T. J., Okuhara, D. Y. & Birnsteil, S. Corticosterone alters 5-HT1A receptor-mediated hyperpolarization in area CA1 hippocampal pyramidal neurons. Neuropsychopharmacology 14, 27-33 (1996).
    • (1996) Neuropsychopharmacology , vol.14 , pp. 27-33
    • Beck, S.G.1    Choi, K.C.2    List, T.J.3    Okuhara, D.Y.4    Birnsteil, S.5
  • 42
    • 0033808255 scopus 로고    scopus 로고
    • Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers
    • Karst, H. et al. Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers. Nature Neurosci. 3, 977-978 (2000).
    • (2000) Nature Neurosci. , vol.3 , pp. 977-978
    • Karst, H.1
  • 43
    • 0032969434 scopus 로고    scopus 로고
    • Rapid glucocorticoid effects on excitatory amino acid levels in the hippocampus: A microdialysis study in freely moving rats
    • Venero, C. & Borrell, J. Rapid glucocorticoid effects on excitatory amino acid levels in the hippocampus: a microdialysis study in freely moving rats. Eur. J. Neurosci. 11, 2465-2473 (1999).
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 2465-2473
    • Venero, C.1    Borrell, J.2
  • 44
    • 0038755185 scopus 로고    scopus 로고
    • Nongenomic glucocorticoid inhibition via endocannabinoid release in the hypothalamus: A fast feedback mechanism
    • Di, S., Malcher-Lopes, R., Halmos, K. C. & Tasker, J. G. Nongenomic glucocorticoid inhibition via endocannabinoid release in the hypothalamus: a fast feedback mechanism. J. Neurosci. 23, 4850-4857 (2003). This study presents evidence for rapid glucocorticoid feedback inhibition of hypothalamic hormone secretion by endocannabinoid release in the PVN.
    • (2003) J. Neurosci. , vol.23 , pp. 4850-4857
    • Di, S.1    Malcher-Lopes, R.2    Halmos, K.C.3    Tasker, J.G.4
  • 45
    • 4644276214 scopus 로고    scopus 로고
    • Cocaine-induced potentiation of synaptic strength in dopamine neurons: Behavioral correlates in GluRA (-/-) mice
    • Dong, Y. et al. Cocaine-induced potentiation of synaptic strength in dopamine neurons: Behavioral correlates in GluRA (-/-) mice. Proc. Natl Acad. Sci. USA 101, 14282-14287 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 14282-14287
    • Dong, Y.1
  • 46
    • 0026938027 scopus 로고
    • Inverted-U relationship between the level of peripheral Corticosterone and the magnitude of hippocampal primed burst potentiation
    • Diamond, D. M., Bennett, M. C., Fleshner, M. & Rose, G. M. Inverted-U relationship between the level of peripheral Corticosterone and the magnitude of hippocampal primed burst potentiation. Hippocampus 2, 421-430 (1992). This research shows that corticosterone exerts a concentration-dependent biphasic influence on the expression of hippocampal plasticity.
    • (1992) Hippocampus , vol.2 , pp. 421-430
    • Diamond, D.M.1    Bennett, M.C.2    Fleshner, M.3    Rose, G.M.4
  • 47
    • 0034042406 scopus 로고    scopus 로고
    • Synaptic plasticity and memory: An evaluation of the hypothesis
    • Martin, S. J., Grimwood, P. D. & Morris, R. G. Synaptic plasticity and memory: an evaluation of the hypothesis. Annu. Rev. Neurosci. 23, 649-711 (2000).
    • (2000) Annu. Rev. Neurosci. , vol.23 , pp. 649-711
    • Martin, S.J.1    Grimwood, P.D.2    Morris, R.G.3
  • 48
    • 0036593119 scopus 로고    scopus 로고
    • The stressed hippocampus, synaptic plasticity and lost memories
    • Kim, J. J. & Diamond, D. The stressed hippocampus, synaptic plasticity and lost memories. Nature Rev. Neurosci. 3, 453-462 (2002).
    • (2002) Nature Rev. Neurosci. , vol.3 , pp. 453-462
    • Kim, J.J.1    Diamond, D.2
  • 49
    • 0030569309 scopus 로고    scopus 로고
    • Role of adrenal steroid mineralocorticoid and glucocorticoid receptors in long-term potentiation in the CA1 field of hippocampal slices
    • Pavlides, C., Ogawa, S., Kimura, A. & McEwen, B. S. Role of adrenal steroid mineralocorticoid and glucocorticoid receptors in long-term potentiation in the CA1 field of hippocampal slices. Brain Res. 738, 229-235 (1996).
    • (1996) Brain Res. , vol.738 , pp. 229-235
    • Pavlides, C.1    Ogawa, S.2    Kimura, A.3    McEwen, B.S.4
  • 50
    • 0032572727 scopus 로고    scopus 로고
    • Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus
    • Xu, L., Anwyl, R. & Rowan, M. J. Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus. Nature 394, 891-894 (1998).
    • (1998) Nature , vol.394 , pp. 891-894
    • Xu, L.1    Anwyl, R.2    Rowan, M.J.3
  • 51
    • 0029978497 scopus 로고    scopus 로고
    • Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation
    • Kim, J. J., Foy, M. R. & Thompson. Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation. Proc. Natl Acad. Sci. USA 93, 4750-4753 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4750-4753
    • Kim, J.J.1    Foy, M.R.2    Thompson3
  • 52
    • 0036581331 scopus 로고    scopus 로고
    • Priming of long-term potentiation in mouse hippocampus by corticotropin-releasing factor and acute stress: Implications for hippocampus-dependent learning
    • Blank, T., Nijholt, I., Eckart, K. & Spiess, J. Priming of long-term potentiation in mouse hippocampus by corticotropin-releasing factor and acute stress: implications for hippocampus-dependent learning. J. Neurosci. 22, 3788-3794 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 3788-3794
    • Blank, T.1    Nijholt, I.2    Eckart, K.3    Spiess, J.4
  • 53
    • 0027368671 scopus 로고
    • Progesterone receptor-mediated effects of neuroactive steroids
    • Rupprecht, R. et al. Progesterone receptor-mediated effects of neuroactive steroids. Neuron 11, 523-530 (1993).
    • (1993) Neuron , vol.11 , pp. 523-530
    • Rupprecht, R.1
  • 54
    • 0041737641 scopus 로고    scopus 로고
    • Stress-related modulation of hippocampal long-term potentiation in rats: Involvement of adrenal steroid receptors
    • Korz, V. & Frey, J. U. Stress-related modulation of hippocampal long-term potentiation in rats: involvement of adrenal steroid receptors. J. Neurosci. 23, 7281-7287 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 7281-7287
    • Korz, V.1    Frey, J.U.2
  • 55
    • 2342565007 scopus 로고    scopus 로고
    • Stress generates emotional memories and retrograde amnesia by inducing an endogenous form of hippocampal LTP
    • Diamond, D. M., Park, C. R. & Woodson, J. C. Stress generates emotional memories and retrograde amnesia by inducing an endogenous form of hippocampal LTP. Hippocampus 14, 281-291 (2004).
    • (2004) Hippocampus , vol.14 , pp. 281-291
    • Diamond, D.M.1    Park, C.R.2    Woodson, J.C.3
  • 56
    • 0026532055 scopus 로고
    • Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning
    • Oitzl, M. S. & de Kloet, E. R. Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning. Behav. Neurosci. 106, 62-71 (1992). This paper shows that corticosteroids affect behavioural strategies and the storage of spatial information through MR and GR in a differential and coordinated manner.
    • (1992) Behav. Neurosci. , vol.106 , pp. 62-71
    • Oitzl, M.S.1    De Kloet, E.R.2
  • 57
    • 0035940455 scopus 로고    scopus 로고
    • Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory
    • Oitzl, M. S., Reichardt, H. M., Joëls, M. & de Kloet, E. R. Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory. Proc. Natl Acad. Sci. USA 98, 12790-12795 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12790-12795
    • Oitzl, M.S.1    Reichardt, H.M.2    Joëls, M.3    De Kloet, E.R.4
  • 58
    • 0030929774 scopus 로고    scopus 로고
    • Experience-dependent facilitating effect of corticosterone on spatial memory formation in the water maze
    • Sandi, C., Loscertales, M. & Guaza, C. Experience-dependent facilitating effect of corticosterone on spatial memory formation in the water maze. Eur. J. Neurosci. 9, 637-642 (1997).
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 637-642
    • Sandi, C.1    Loscertales, M.2    Guaza, C.3
  • 59
    • 0031458855 scopus 로고    scopus 로고
    • Glucocorticoid enhancement of memory storage involves noradrenergic activation in the basolateral amygdala
    • Quirarte, G. L., Roozendaal, B. & McGaugh, J. L. Glucocorticoid enhancement of memory storage involves noradrenergic activation in the basolateral amygdala. Proc. Natl Acad. Sci. USA 94, 14048-14053 (1997). This study shows that β-adrenergic activation seems to be an essential step in mediating glucocorticoid effects on memory storage and that the BLA is a locus of interaction for these two systems.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14048-14053
    • Quirarte, G.L.1    Roozendaal, B.2    McGaugh, J.L.3
  • 60
    • 0032552049 scopus 로고    scopus 로고
    • Stress and glucocorticoids impair retrieval of long-term spatial memory
    • De Quervain, D. J., Roozendaal, B. & McGaugh, J. L. Stress and glucocorticoids impair retrieval of long-term spatial memory. Nature 394, 787-790 (1998).
    • (1998) Nature , vol.394 , pp. 787-790
    • De Quervain, D.J.1    Roozendaal, B.2    McGaugh, J.L.3
  • 61
    • 0037079060 scopus 로고    scopus 로고
    • Behavioral and neural analysis of extinction
    • Myers, K. M. & Davis, M. Behavioral and neural analysis of extinction. Neuron 36, 567-584 (2002).
    • (2002) Neuron , vol.36 , pp. 567-584
    • Myers, K.M.1    Davis, M.2
  • 62
    • 2442756226 scopus 로고    scopus 로고
    • Correlational relationship between shock intensity and corticosterone secretion on the establishment and subsequent expression of contextual fear conditioning
    • Cordero, M. I., Merino, J. J. & Sandi, C. Correlational relationship between shock intensity and corticosterone secretion on the establishment and subsequent expression of contextual fear conditioning. Behav. Neurosci. 112, 885-891 (1998).
    • (1998) Behav. Neurosci. , vol.112 , pp. 885-891
    • Cordero, M.I.1    Merino, J.J.2    Sandi, C.3
  • 63
    • 0036457088 scopus 로고    scopus 로고
    • Glucocorticoids alter calcium conductances and calcium channel subunit expression in basolateral amygdala neurons
    • Karst, H. et al. Glucocorticoids alter calcium conductances and calcium channel subunit expression in basolateral amygdala neurons. Eur. J. Neurosci. 16, 1083-1089 (2002).
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 1083-1089
    • Karst, H.1
  • 64
    • 1842633510 scopus 로고    scopus 로고
    • Effects of inescapable stress on LTP in the amygdala versus the dentate gyrus of freely behaving rats
    • Vouimba, R. M., Yaniv, D., Diamond, D. & Richter-Levin, G. Effects of inescapable stress on LTP in the amygdala versus the dentate gyrus of freely behaving rats. Eur. J. Neurosci. 19, 1887-1894 (2004),
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1887-1894
    • Vouimba, R.M.1    Yaniv, D.2    Diamond, D.3    Richter-Levin, G.4
  • 65
    • 0035879171 scopus 로고    scopus 로고
    • Amygdala is critical for stress-induced modulation of hippocampal long-term potentiation and learning
    • Kim, J. J., Lee, H. J., Man, J. S. & Packard, M. G. Amygdala is critical for stress-induced modulation of hippocampal long-term potentiation and learning. J. Neurosci. 21, 5222-5228 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 5222-5228
    • Kim, J.J.1    Lee, H.J.2    Man, J.S.3    Packard, M.G.4
  • 66
    • 0037112253 scopus 로고    scopus 로고
    • Mechanisms of amygdala modulation of hippocampal plasticity
    • Akirav, I. & Richter-Levin, G. Mechanisms of amygdala modulation of hippocampal plasticity. J. Neurosci. 22 912-921 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 912-921
    • Akirav, I.1    Richter-Levin, G.2
  • 67
    • 0038118287 scopus 로고    scopus 로고
    • Exposure to acute stress blocks the induction of long-term potentiation of the amygdala-prefrontal cortex pathway in vivo
    • Maroun, M. & Richter-Levin, G. Exposure to acute stress blocks the induction of long-term potentiation of the amygdala-prefrontal cortex pathway in vivo J. Neurosci. 23, 4406-4409 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 4406-4409
    • Maroun, M.1    Richter-Levin, G.2
  • 68
    • 14544297378 scopus 로고    scopus 로고
    • Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus
    • Amat, J. et al. Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus. Nature Neurosci. 8, 365-371 (2005).
    • (2005) Nature Neurosci. , vol.8 , pp. 365-371
    • Amat, J.1
  • 69
    • 0343750698 scopus 로고    scopus 로고
    • Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy
    • Conrad, C. D., LeDoux, J. E., Magarinos, A. M. & McEwen, B. S. Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behav. Neurosci. 113, 902-913 (1999).
    • (1999) Behav. Neurosci. , vol.113 , pp. 902-913
    • Conrad, C.D.1    LeDoux, J.E.2    Magarinos, A.M.3    McEwen, B.S.4
  • 70
    • 0344406811 scopus 로고    scopus 로고
    • Chronic stress effects on memory: Sex differences in performance and monoaminergic activity
    • Bowman, R. E., Beck, K. D. & Luine, V. N. Chronic stress effects on memory: sex differences in performance and monoaminergic activity. Horm. Behav. 43, 48-59 (2003).
    • (2003) Horm. Behav. , vol.43 , pp. 48-59
    • Bowman, R.E.1    Beck, K.D.2    Luine, V.N.3
  • 71
    • 0025168942 scopus 로고
    • Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons
    • Woolley, C. S., Gould, E. & McEwen, B. S. Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons. Brain Res. 531, 225-231 (1990). In this study, changes in dendritic morphology were observed that might have been indicative of neurons in the early stages of degeneration
    • (1990) Brain Res. , vol.531 , pp. 225-231
    • Woolley, C.S.1    Gould, E.2    McEwen, B.S.3
  • 72
    • 0029988191 scopus 로고    scopus 로고
    • Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews
    • Magarinos, A. M., McEwen, B. S., Flugge, G. & Fuchs, E. Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews. J. Neurosci. 16, 3534-3540 (1996). These results indicate that a naturalistic psychosocial stressor induces specific structural changes in the hippocampal neurons of subordinate male tree shrews.
    • (1996) J. Neurosci. , vol.16 , pp. 3534-3540
    • Magarinos, A.M.1    McEwen, B.S.2    Flugge, G.3    Fuchs, E.4
  • 73
    • 0037715009 scopus 로고    scopus 로고
    • Rapid reversal of stress induced loss of synapses in CA3 of rat hippocampus following water maze training
    • Sandi, C. et al. Rapid reversal of stress induced loss of synapses in CA3 of rat hippocampus following water maze training. Eur. J. Neurosci. 17, 2447-2456 (2003).
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 2447-2456
    • Sandi, C.1
  • 74
    • 0035889662 scopus 로고    scopus 로고
    • Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration
    • Wellman, C. L. Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration. J. Neurobiol. 49, 245-253 (2001).
    • (2001) J. Neurobiol. , vol.49 , pp. 245-253
    • Wellman, C.L.1
  • 75
    • 0036703905 scopus 로고    scopus 로고
    • Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons
    • Vyas, A., Mitra, R., Shankaranarayana Rao, B. S. & Chattarji, S. Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons. J. Neurosci. 22, 6810-6818 (2002). The data presented here indicate that chronic stress can cause contrasting patterns of dendritic remodelling in neurons of the amygdala and hippocampus.
    • (2002) J. Neurosci. , vol.22 , pp. 6810-6818
    • Vyas, A.1    Mitra, R.2    Shankaranarayana Rao, B.S.3    Chattarji, S.4
  • 76
    • 13144305132 scopus 로고    scopus 로고
    • Chronic stress alters synaptic terminal structure in hippocampus
    • Magarinos, A. M., Verdugo, J. M. & McEwen, B. S. Chronic stress alters synaptic terminal structure in hippocampus. Proc. Natl Acad. Sci. USA 94, 14002-14008 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14002-14008
    • Magarinos, A.M.1    Verdugo, J.M.2    McEwen, B.S.3
  • 77
    • 18744401321 scopus 로고    scopus 로고
    • Tne antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats
    • Kole, M. H., Swan, L. & Fuchs, E. Tne antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats. Eur. J. Neurosci. 16, 807-816 (2002).
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 807-816
    • Kole, M.H.1    Swan, L.2    Fuchs, E.3
  • 78
    • 0037252835 scopus 로고    scopus 로고
    • Effect of chronic stress on synaptic currents in rat hippocampal dentate gyrus neurons
    • Karst, H. & Joëls, M. Effect of chronic stress on synaptic currents in rat hippocampal dentate gyrus neurons. J. Neurophysiol. 89, 625-633 (2003).
    • (2003) J. Neurophysiol. , vol.89 , pp. 625-633
    • Karst, H.1    Joëls, M.2
  • 79
    • 0038054209 scopus 로고    scopus 로고
    • Chronic unpredictable stress impairs long-term potentiation in rat hippocampal CA1 area and dentate gyrus in vitro
    • Alfarez, D. N., Joëls, M. & Krugers, H. J. Chronic unpredictable stress impairs long-term potentiation in rat hippocampal CA1 area and dentate gyrus in vitro. Eur. J. Neurosci. 17, 1928-1934 (2003).
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 1928-1934
    • Alfarez, D.N.1    Joëls, M.2    Krugers, H.J.3
  • 80
    • 0037293553 scopus 로고    scopus 로고
    • Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus
    • Pham, K., Nacher, J., Hof, P. R. & McEwen, B. S. Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus. Eur. J. Neurosci. 17, 879-886 (2003).
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 879-886
    • Pham, K.1    Nacher, J.2    Hof, P.R.3    McEwen, B.S.4
  • 81
    • 0035940496 scopus 로고    scopus 로고
    • Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
    • Czeh, B. et al. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc. Natl Acad. Sci. USA 98, 12796-12801 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12796-12801
    • Czeh, B.1
  • 82
    • 9644281636 scopus 로고    scopus 로고
    • The corticoid environment: A determining factor for neural progenitors' survival in the adult hippocampus
    • Wong, E. Y. & Herbert, J. The corticoid environment: a determining factor for neural progenitors' survival in the adult hippocampus. Eur. J. Neurosci. 20, 2491-2498 (2004).
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 2491-2498
    • Wong, E.Y.1    Herbert, J.2
  • 83
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg, J. E., Eisch, A. J., Nestler, E. J. & Duman, R. S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci. 20, 9104-9110 (2000).
    • (2000) J. Neurosci. , vol.20 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 84
    • 1942502215 scopus 로고    scopus 로고
    • Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression
    • Alonso, R. et al. Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression. Mol. Psychiatry 9, 278-286 (2004).
    • (2004) Mol. Psychiatry , vol.9 , pp. 278-286
    • Alonso, R.1
  • 85
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli, L. et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301, 805-809 (2003). The authors show that the behavioural effects of chronic antidepressant use might be mediated by the stimulation of neurogenesis in the hippocampus.
    • (2003) Science , vol.301 , pp. 805-809
    • Santarelli, L.1
  • 86
    • 0037073573 scopus 로고    scopus 로고
    • Increased astrocyte reactivity in the hippocampus of murine models of type 1 diabetes: The nonobese diabetic (NOD) and streptozotocin-treated mice
    • Saravia, F. E. et al. Increased astrocyte reactivity in the hippocampus of murine models of type 1 diabetes: the nonobese diabetic (NOD) and streptozotocin-treated mice. Brain Res. 13, 345-353 (2002).
    • (2002) Brain Res. , vol.13 , pp. 345-353
    • Saravia, F.E.1
  • 87
    • 0025735507 scopus 로고
    • Bran corticosteroid balance and homeostatic control
    • De Kloet, E. R. Bran corticosteroid balance and homeostatic control. Front. Neuroendocrinol. 12, 95-164 (1991).
    • (1991) Front. Neuroendocrinol. , vol.12 , pp. 95-164
    • De Kloet, E.R.1
  • 88
    • 0033305053 scopus 로고    scopus 로고
    • Defense of adrenocorticosteroid receptor expression in rat hippocampus: Effects of stress and strain
    • Herman, J. P., Watson, S. J. & Spencer, R. L. Defense of adrenocorticosteroid receptor expression in rat hippocampus: effects of stress and strain. Endocrinology 140, 3981-3991 (1999).
    • (1999) Endocrinology , vol.140 , pp. 3981-3991
    • Herman, J.P.1    Watson, S.J.2    Spencer, R.L.3
  • 89
    • 1342265730 scopus 로고    scopus 로고
    • DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor mediated transcription in hippocampal cells: Toward a basis for the opposite actions elicited by two nuclear receptors?
    • Obradovic, D. et al. DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor mediated transcription in hippocampal cells: toward a basis for the opposite actions elicited by two nuclear receptors? Mol. Pharmacol. 65, 761-769 (2004).
    • (2004) Mol. Pharmacol. , vol.65 , pp. 761-769
    • Obradovic, D.1
  • 90
    • 14244261260 scopus 로고    scopus 로고
    • Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signaling
    • Meijer, O. C. et al. Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signaling. Endocrinology 146, 1438-1448 (2005).
    • (2005) Endocrinology , vol.146 , pp. 1438-1448
    • Meijer, O.C.1
  • 91
    • 0033539660 scopus 로고    scopus 로고
    • Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons
    • Karten, Y. J., Nair, S. M., van Essen, L., Sibug, R. & Joëls, M. Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons. Proc. Natl Acad. Sci. USA 96, 13456-13461 (1999). This study shows that prolonged elevation of the corticosteroid concentration, which is a possible causative factor for depression in humans, gradually attenuates responsiveness to serotonin without necessarily decreasing serotonin-1 A receptor mRNA levels in pyramidal neurons.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 13456-13461
    • Karten, Y.J.1    Nair, S.M.2    Van Essen, L.3    Sibug, R.4    Joëls, M.5
  • 92
    • 12144285775 scopus 로고    scopus 로고
    • Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress
    • Froger, N. et al. Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress. J. Neurosci. 24, 2787-2796 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 2787-2796
    • Froger, N.1
  • 93
    • 0032521829 scopus 로고    scopus 로고
    • Bennett Research Award. Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: Implications for the neurobiology of depression
    • Lopez, J. F., Chalmers, D. T., Little, K. Y. & Watson, S. J. A. E. Bennett Research Award. Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: implications for the neurobiology of depression. Biol. Psychol. 43, 547-573 (1998).
    • (1998) Biol. Psychol. , vol.43 , pp. 547-573
    • Lopez, J.F.1    Chalmers, D.T.2    Little, K.Y.3    Watson, S.J.A.E.4
  • 94
    • 3242738309 scopus 로고    scopus 로고
    • Brain circuits involved in corticotropin-releasing factor-norepinephrine interactions during stress
    • Dunn, A. J., Swiergiel, A. H. & Palamarchouk, V. Brain circuits involved in corticotropin-releasing factor-norepinephrine interactions during stress. Ann. NY Acad. Sci. 1018, 25-34 (2004).
    • (2004) Ann. NY Acad. Sci. , vol.1018 , pp. 25-34
    • Dunn, A.J.1    Swiergiel, A.H.2    Palamarchouk, V.3
  • 95
    • 0028216219 scopus 로고
    • Opposite responses of mesolimbic dopamine system to controllable and uncontrollable aversive experiences
    • Cabib, S. & Puglisi-Allegra, S. Opposite responses of mesolimbic dopamine system to controllable and uncontrollable aversive experiences. J. Neurosci. 14, 3333-3340 (1994).
    • (1994) J. Neurosci. , vol.14 , pp. 3333-3340
    • Cabib, S.1    Puglisi-Allegra, S.2
  • 96
    • 0027939457 scopus 로고
    • Increased glucocorticoid receptor gene expression in the rat hippocampus following combined serotonergic and medial septal cholinergic lesions
    • Yau, J. L., Kelly, P. A. & Seckl, J. R. Increased glucocorticoid receptor gene expression in the rat hippocampus following combined serotonergic and medial septal cholinergic lesions. Brain Res. Mol. Brain Res. 27, 174-178 (1994).
    • (1994) Brain Res. Mol. Brain Res. , vol.27 , pp. 174-178
    • Yau, J.L.1    Kelly, P.A.2    Seckl, J.R.3
  • 97
    • 0026709228 scopus 로고
    • Hippocampal type I and type II corticosteroid receptors are modulated by central noradrenergic systems
    • Maccari, S. et al. Hippocampal type I and type II corticosteroid receptors are modulated by central noradrenergic systems. Psychoneuroendocrinology 17, 103-112 (1992).
    • (1992) Psychoneuroendocrinology , vol.17 , pp. 103-112
    • Maccari, S.1
  • 98
    • 0027293611 scopus 로고
    • Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system
    • Reul, J. M., Stec, I., Soder, M. & Holsboer, F. Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system. Endocrinology 133, 312-320 (1993). This paper indicates that during amitriptyline treatment, a rise in limbic MR might be the initial phenomenon in a successively adjusting HPA system, as evidenced by the decreasing plasma hormone concentrations, declining adrenal size and upregulation of GR in particular brain regions.
    • (1993) Endocrinology , vol.133 , pp. 312-320
    • Reul, J.M.1    Stec, I.2    Soder, M.3    Holsboer, F.4
  • 99
    • 0038066569 scopus 로고    scopus 로고
    • Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture
    • Lai, M. et al. Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture. Neuroscience 118, 975-984 (2003).
    • (2003) Neuroscience , vol.118 , pp. 975-984
    • Lai, M.1
  • 100
    • 2542541326 scopus 로고    scopus 로고
    • Mineralo- and glucocorticoid receptor mRNAs are differently regulated by corticosterone in the rat hippocampus and anterior pituitary
    • Hugin-Flores, M. E., Steimer, T., Aubert, M. L. & Schulz, P. Mineralo- and glucocorticoid receptor mRNAs are differently regulated by corticosterone in the rat hippocampus and anterior pituitary. Neuroendocrinology 79, 174-184 (2004).
    • (2004) Neuroendocrinology , vol.79 , pp. 174-184
    • Hugin-Flores, M.E.1    Steimer, T.2    Aubert, M.L.3    Schulz, P.4
  • 101
    • 18044402645 scopus 로고    scopus 로고
    • Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice
    • Gass, P. et al. Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice. EMBO Rep. 5, 447-451 (2000).
    • (2000) EMBO Rep. , vol.5 , pp. 447-451
    • Gass, P.1
  • 102
    • 0032829658 scopus 로고    scopus 로고
    • Increased basal activity of the HPA axis and renin angiotensin system in congenital learned helpless rats exposed to stress early in development
    • Edwards, E., King, J. A. & Fray, J. C. Increased basal activity of the HPA axis and renin angiotensin system in congenital learned helpless rats exposed to stress early in development. Int. J. Dev. Neurosci. 17, 805-812 (1999).
    • (1999) Int. J. Dev. Neurosci. , vol.17 , pp. 805-812
    • Edwards, E.1    King, J.A.2    Fray, J.C.3
  • 103
    • 4043087852 scopus 로고    scopus 로고
    • Genetic background, nature of event, and time of exposure to event direct the phenotypic expression of a particular genotype. A study with apomorphine-(un)susceptible Wistar rats
    • Degen, S. B., Verheij, M. M. & Cools, A. R. Genetic background, nature of event, and time of exposure to event direct the phenotypic expression of a particular genotype. A study with apomorphine-(un)susceptible Wistar rats. Behav. Brain Res. 154, 107-112 (2004).
    • (2004) Behav. Brain Res. , vol.154 , pp. 107-112
    • Degen, S.B.1    Verheij, M.M.2    Cools, A.R.3
  • 104
    • 0036147367 scopus 로고    scopus 로고
    • Vasopressin mediates the response of the combined dexamethasone/CRH test in hyper-anxious rats: Implications for pathogenesis of affective disorders
    • Keck, M. E. et al. Vasopressin mediates the response of the combined dexamethasone/CRH test in hyper-anxious rats: implications for pathogenesis of affective disorders. Neuropsychopharmacology 26, 94-105 (2002).
    • (2002) Neuropsychopharmacology , vol.26 , pp. 94-105
    • Keck, M.E.1
  • 105
    • 0037534926 scopus 로고    scopus 로고
    • Born to be anxious: Neuroendocrine and genetic correlates of trait anxiety in HAB rats
    • Landgraf, R. & Wigger, A. Born to be anxious: neuroendocrine and genetic correlates of trait anxiety in HAB rats. Stress 6, 111-119 (2003).
    • (2003) Stress , vol.6 , pp. 111-119
    • Landgraf, R.1    Wigger, A.2
  • 106
    • 4444325412 scopus 로고    scopus 로고
    • Impaired repression at a vasopressin promoter polymorphism underlies overexpression of vasopressin in a rat model of trait anxiety
    • Murgatroyd, C. et al. Impaired repression at a vasopressin promoter polymorphism underlies overexpression of vasopressin in a rat model of trait anxiety. J. Neurosci. 24, 7762-7770 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 7762-7770
    • Murgatroyd, C.1
  • 107
    • 0023494912 scopus 로고
    • Neuroendocrine states and behavioral and physiological stress responses
    • Bohus, B. et al. Neuroendocrine states and behavioral and physiological stress responses. Prog. Brain Res. 72, 57-70 (1987).
    • (1987) Prog. Brain Res. , vol.72 , pp. 57-70
    • Bohus, B.1
  • 108
    • 11844304310 scopus 로고    scopus 로고
    • The Darwinian concept of stress: Benefits of allostasis and costs of allostatic load and the trade-offs in health and disease
    • Korte, S. M., Koolhaas, J. M., Wingfield, J. C. & McEwen, B. S. The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade-offs in health and disease. Neurosci. Biobehav. Rev. 29, 3-38 (2005).
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 3-38
    • Korte, S.M.1    Koolhaas, J.M.2    Wingfield, J.C.3    McEwen, B.S.4
  • 109
  • 110
    • 0037263690 scopus 로고    scopus 로고
    • Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice
    • Feldker, D. E. et al. Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice. Eur. J. Neurosci. 17, 379-387 (2003).
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 379-387
    • Feldker, D.E.1
  • 111
  • 112
    • 0033527727 scopus 로고    scopus 로고
    • Nongenomic transmission across generations of maternal behavior and stress responses in the rat
    • Francis, D., Diorio, J., Liu, D. & Meaney, M. J. Nongenomic transmission across generations of maternal behavior and stress responses in the rat. Science 286, 1155-1158 (1999).
    • (1999) Science , vol.286 , pp. 1155-1158
    • Francis, D.1    Diorio, J.2    Liu, D.3    Meaney, M.J.4
  • 113
    • 2042468714 scopus 로고
    • Infantile experience and resistance to physiological stress
    • Levine, S. Infantile experience and resistance to physiological stress. Science 126, 405 (1957).
    • (1957) Science , vol.126 , pp. 405
    • Levine, S.1
  • 115
    • 0023877370 scopus 로고
    • Effect of neonatal handling on age-related impairments associated with the hippocampus
    • Meaney, M. J., Aitken, D. H., van Berkel, C., Bhatnagar, S. & Sapolsky, R. M. Effect of neonatal handling on age-related impairments associated with the hippocampus. Science 12, 766-768 (1988).
    • (1988) Science , vol.12 , pp. 766-768
    • Meaney, M.J.1    Aitken, D.H.2    Van Berkel, C.3    Bhatnagar, S.4    Sapolsky, R.M.5
  • 116
    • 15144344289 scopus 로고    scopus 로고
    • Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress
    • Liu, D. et al. Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. Science 277, 1659-1662 (1997).
    • (1997) Science , vol.277 , pp. 1659-1662
    • Liu, D.1
  • 117
    • 3342989681 scopus 로고    scopus 로고
    • Epigenetic programming by maternal behavior
    • Weaver, I. C. G. et al. Epigenetic programming by maternal behavior. Nature Neurosci. 7, 847-854 (2004). These data indicate that a potentially reversible epigenomic state of a gene can be established through behavioural programming.
    • (2004) Nature Neurosci. , vol.7 , pp. 847-854
    • Weaver, I.C.G.1
  • 118
    • 1042277738 scopus 로고    scopus 로고
    • Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation
    • Ladd, C. O., Huot, R. L., Thrivikraman, K. V. Nemeroff, C. B. & Plotsky, P. M. Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation. Biol. Psychiatry 55, 367-375 (2004).
    • (2004) Biol. Psychiatry , vol.55 , pp. 367-375
    • Ladd, C.O.1    Huot, R.L.2    Thrivikraman, K.V.3    Nemeroff, C.B.4    Plotsky, P.M.5
  • 119
    • 0033783716 scopus 로고    scopus 로고
    • Maternal deprivation affects behaviour from youth to senescence: Amplification of individual differences in spatial learning and memory in senescent Brown Norway rats
    • Oitzl, M. S., Workel, J. O., Futtert, M., Frosch, F. & de Kloet, E. R. Maternal deprivation affects behaviour from youth to senescence: amplification of individual differences in spatial learning and memory in senescent Brown Norway rats. Eur. J. Neurosci. 12, 3771-3780 (2000).
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 3771-3780
    • Oitzl, M.S.1    Workel, J.O.2    Futtert, M.3    Frosch, F.4    De Kloet, E.R.5
  • 120
    • 2542616761 scopus 로고    scopus 로고
    • Effect of early life stress on serotonin responses in the hippocampus of young adult rats
    • Van Riel, E., van Gemert, N. G., Meijer, O. C. & Joëls, M. Effect of early life stress on serotonin responses in the hippocampus of young adult rats. Synapse 53, 11-19 (2004).
    • (2004) Synapse , vol.53 , pp. 11-19
    • Van Riel, E.1    Van Gemert, N.G.2    Meijer, O.C.3    Joëls, M.4
  • 121
    • 0029928064 scopus 로고    scopus 로고
    • Persistent elevations of cerebrospinal fluid concentrations of corticotrophin releasing factor in adult nonhuman primates exposed to early-life stressors: Implications for the pathophysiology of mood and anxiety disorders
    • Coplan, J. D. et al. Persistent elevations of cerebrospinal fluid concentrations of corticotrophin releasing factor in adult nonhuman primates exposed to early-life stressors: implications for the pathophysiology of mood and anxiety disorders. Proc. Natl Acad. Sci. USA 93, 1619-1623 (1996). These data indicate a potential neurobiological mechanism in non-human primates by which early-life stressors might contribute to adult psychopathology.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1619-1623
    • Coplan, J.D.1
  • 122
    • 0029052174 scopus 로고
    • Stressful life events genetic liability, and onset of an episode of major depression in women
    • Kendler, K. S. et al. Stressful life events, genetic liability, and onset of an episode of major depression in women. Am. J. Psychiatry 152, 833-842 (1995).
    • (1995) Am. J. Psychiatry , vol.152 , pp. 833-842
    • Kendler, K.S.1
  • 123
    • 0345791453 scopus 로고    scopus 로고
    • Association of depression with medical illness: Does cortisol play a role?
    • Brown, E. S., Varghese, F. P. & McEwen, B. S. Association of depression with medical illness: does cortisol play a role? Biol. Psychiatry 55, 1-9 (2004).
    • (2004) Biol. Psychiatry , vol.55 , pp. 1-9
    • Brown, E.S.1    Varghese, F.P.2    McEwen, B.S.3
  • 124
    • 0032057656 scopus 로고    scopus 로고
    • Cortisol levels during human aging predict hippocampal atrophy and memory deficits
    • Lupien, S. J. et al. Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nature Neurosci. 1, 69-73 (1998). This study presents evidence that basal cortisol elevation might cause hippocampal damage and impair hippocampus-dependent learning and memory in humans.
    • (1998) Nature Neurosci. , vol.1 , pp. 69-73
    • Lupien, S.J.1
  • 125
    • 0033564043 scopus 로고    scopus 로고
    • Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression
    • Sheline, Y. I., Sanghavi, M., Mintun, M. A. & Gado, M. H. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. J. Neurosci. 19, 5034-5043 (1999).
    • (1999) J. Neurosci. , vol.19 , pp. 5034-5043
    • Sheline, Y.I.1    Sanghavi, M.2    Mintun, M.A.3    Gado, M.H.4
  • 126
    • 0035784124 scopus 로고    scopus 로고
    • Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus
    • Müller, M. B. et al. Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus. Eur. J. Neurosci. 14, 1603-1612 (2001).
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 1603-1612
    • Müller, M.B.1
  • 127
    • 0032842478 scopus 로고    scopus 로고
    • Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
    • Tronche, F. et al. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nature Genet. 23, 99-103 (1999). The authors show that conditional mutagenesis of GR in the nervous system provides genetic evidence for the importance of GR signalling in emotional behaviour
    • (1999) Nature Genet. , vol.23 , pp. 99-103
    • Tronche, F.1
  • 128
    • 12244264438 scopus 로고    scopus 로고
    • Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior
    • Boyle, M. P. et al. Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior. Proc. Natl Acad. Sci. USA 102, 473-478 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 473-478
    • Boyle, M.P.1
  • 129
    • 4143091546 scopus 로고    scopus 로고
    • Glucocorticoid receptor overexpression in forebrain: A mouse model of increased emotional lability
    • Wei, Q. et al. Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc. Natl Acad. Sci. USA 101, 11851-11856 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 11851-11856
    • Wei, Q.1
  • 130
    • 0032104267 scopus 로고    scopus 로고
    • Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuraendocrine development
    • Smith, G. W. et al. Corticotropin releasing factor receptor 1 -deficient mice display decreased anxiety, impaired stress response, and aberrant neuraendocrine development. Neuron 20, 1093-1102 (1998).
    • (1998) Neuron , vol.20 , pp. 1093-1102
    • Smith, G.W.1
  • 131
    • 17344362093 scopus 로고    scopus 로고
    • Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1
    • Timpl, P. et al. Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. Nature Genet. 19, 162-166 (1998).
    • (1998) Nature Genet. , vol.19 , pp. 162-166
    • Timpl, P.1
  • 132
    • 0141542646 scopus 로고    scopus 로고
    • Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
    • Müller, M. B. et al. Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress. Nature Neurosci. 6, 1100-1107 (2003). This study presents evidence that limbic CRHR1 modulates anxiety-related behaviour independent of HPA-axis function.
    • (2003) Nature Neurosci. , vol.6 , pp. 1100-1107
    • Müller, M.B.1
  • 133
    • 0027081914 scopus 로고
    • Antidepressant drug action in a transgenic mouse model of the endocrine changes seen in depression
    • Pepin, M. C., Pothier, F. & Barden, N. Antidepressant drug action in a transgenic mouse model of the endocrine changes seen in depression. Mol. Pharmacol. 42, 991-995 (1992).
    • (1992) Mol. Pharmacol. , vol.42 , pp. 991-995
    • Pepin, M.C.1    Pothier, F.2    Barden, N.3
  • 134
    • 0027988726 scopus 로고
    • The combined dexamethasone/CRH test: A refined laboratory test for psychiatric disorders
    • Heuser, I., Yassouridis, A. & Holsboer, F. The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders. J. Psychiatr. Res. 28, 341-356 (1994).
    • (1994) J. Psychiatr. Res. , vol.28 , pp. 341-356
    • Heuser, I.1    Yassouridis, A.2    Holsboer, F.3
  • 135
    • 0031732606 scopus 로고    scopus 로고
    • Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice
    • Meijer, O. C. et al. Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice. Endocrinology 139, 1789-1793 (1998).
    • (1998) Endocrinology , vol.139 , pp. 1789-1793
    • Meijer, O.C.1
  • 136
    • 0030032350 scopus 로고    scopus 로고
    • Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression
    • Purba, J. S., Hoogendijk, W. J., Hofman, M. A. & Swaab, D. F. Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression. Arch Gen. Psychiatry 53, 137-143 (1996).
    • (1996) Arch Gen. Psychiatry , vol.53 , pp. 137-143
    • Purba, J.S.1    Hoogendijk, W.J.2    Hofman, M.A.3    Swaab, D.F.4
  • 137
    • 0034993647 scopus 로고    scopus 로고
    • Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression. A prospective study
    • Zobel, A. W. et al. Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression. A prospective study. J. Psychiatr. Res. 35, 83-94 (2001).
    • (2001) J. Psychiatr. Res. , vol.35 , pp. 83-94
    • Zobel, A.W.1
  • 138
    • 0031885081 scopus 로고    scopus 로고
    • Hormonal response pattern in the combined DEX-CRH test is stable over time in subjects at high familial risk for affective disorders
    • Modell, S. et al. Hormonal response pattern in the combined DEX-CRH test is stable over time in subjects at high familial risk for affective disorders Neuropsychopharmacology 18, 253-262 (1998).
    • (1998) Neuropsychopharmacology , vol.18 , pp. 253-262
    • Modell, S.1
  • 139
    • 0035197083 scopus 로고    scopus 로고
    • Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters
    • Pariante, C. M. et al. Antidepressants enhance glucocorticoid receptor function In vitro by modulating the membrane steroid transporters. Br. J. Pharmacol. 134, 1335-1343 (2001).
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 1335-1343
    • Pariante, C.M.1
  • 140
    • 0033810465 scopus 로고    scopus 로고
    • Genetic epidemiology of major depression: Review and meta-analysis
    • Sullivan, P. F., Neale, M. C. & Kendler, K. S. Genetic epidemiology of major depression: review and meta-analysis. Am. J. Psychiatry 157, 1552-1562 (2000).
    • (2000) Am. J. Psychiatry , vol.157 , pp. 1552-1562
    • Sullivan, P.F.1    Neale, M.C.2    Kendler, K.S.3
  • 141
    • 0035875146 scopus 로고    scopus 로고
    • The role of childhood trauma in the neurobiology of mood and anxiety disorders: Preclinical and clinical studies
    • Heim, C. & Nemeroff, C. B. The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol. Psychiatry 49, 1023-1039 (2001).
    • (2001) Biol. Psychiatry , vol.49 , pp. 1023-1039
    • Heim, C.1    Nemeroff, C.B.2
  • 142
    • 0036891102 scopus 로고    scopus 로고
    • Hyperresponsiveness of hypothalamic-pituitary-adrenal axis to combined dexamethasone/corticotropin-releasing hormone challenge in female borderline personality disorder subjects with a history of sustained childhood abuse
    • Rinne, T. et al. Hyperresponsiveness of hypothalamic-pituitary-adrenal axis to combined dexamethasone/corticotropin-releasing hormone challenge in female borderline personality disorder subjects with a history of sustained childhood abuse. Biol. Psychiatry 52, 1102-1112 (2002).
    • (2002) Biol. Psychiatry , vol.52 , pp. 1102-1112
    • Rinne, T.1
  • 144
    • 1942424245 scopus 로고    scopus 로고
    • Basal and dexamethasone suppressed salivary cortisol concentrations in a community sample of patients with posttraumatic stress disorder
    • Lindley, S. E., Carlson, E. B. & Benoit, M. Basal and dexamethasone suppressed salivary cortisol concentrations in a community sample of patients with posttraumatic stress disorder. Biol. Psychiatry 55, 940-945 (2004).
    • (2004) Biol. Psychiatry , vol.55 , pp. 940-945
    • Lindley, S.E.1    Carlson, E.B.2    Benoit, M.3
  • 145
    • 9644252785 scopus 로고    scopus 로고
    • Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment
    • Binder, E. B. et al. Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nature Genet. 36, 1319-1325 (2004). Individuals carrying a polymorphism in FKBP5, a GR-regulating co-chaperone, showed less HPA axis hyperactivity and a significant association with the response to antidepressants.
    • (2004) Nature Genet. , vol.36 , pp. 1319-1325
    • Binder, E.B.1
  • 146
    • 20044364163 scopus 로고    scopus 로고
    • FKBP51 and FKBP52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells
    • in the press
    • Wochnik, G. M. et al. FKBP51 and FKBP52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells. J. Biol. Chem. (in the press).
    • J. Biol. Chem.
    • Wochnik, G.M.1
  • 147
    • 2342425073 scopus 로고    scopus 로고
    • Polymorphisms in the glucocorticoid receptor gene and their associations with metabolic parameters and body composition
    • van Rossum, E. F. & Lamberts, S. W. Polymorphisms in the glucocorticoid receptor gene and their associations with metabolic parameters and body composition. Recent Prog. Horm. Res. 59, 333-357 (2004).
    • (2004) Recent Prog. Horm. Res. , vol.59 , pp. 333-357
    • Van Rossum, E.F.1    Lamberts, S.W.2
  • 148
    • 1442352192 scopus 로고    scopus 로고
    • Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype
    • Stevens, A. et al. Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype. J. Clin. Endocrinol. Metab. 89, 892-897 (2004).
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 892-897
    • Stevens, A.1
  • 149
    • 10744232835 scopus 로고    scopus 로고
    • Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress
    • Wüst, S. et al. Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress. J. Clin. Endocrinol. Metab. 89, 565-573 (2004). This was the first report to document an effect of GR gene polymorphisms on cortisol responses to psychosocial stress that might contribute to individual vulnerability to HPA-related disorders.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 565-573
    • Wüst, S.1
  • 150
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • Caspi, A. et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301, 386-389 (2003). An epidemiological study that provides evidence of a gene-by-environment interaction, in which the response of an individual to environmental insults is moderated by genetic makeup.
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1
  • 151
    • 4344606342 scopus 로고    scopus 로고
    • Restructuring the neuronal stress response with anti-glucocorticoid gene delivery
    • Kaufer, D. et al. Restructuring the neuronal stress response with anti-glucocorticoid gene delivery. Nature Neurosci. 7 947-953 (2004). In this study, a genetic strategy diminished the neurological damage inflicted by glucocorticoids in the hippocampus. In particular, a chimeric receptor combining the ligand-binding domain of the glucocorticoid receptor and the DNA-binding domain of the oestrogen receptor seemed effective.
    • (2004) Nature Neurosci. , vol.7 , pp. 947-953
    • Kaufer, D.1
  • 152
    • 7444240354 scopus 로고    scopus 로고
    • 11β-hydroxysteroid dehydrogenase type 1 as a modulator of glucocorticoid action: From metabolism to memory
    • Seckl, J. R. & Walker, B. R. 11β-hydroxysteroid dehydrogenase type 1 as a modulator of glucocorticoid action: from metabolism to memory. Trends Endocrinol. Metab. 15, 418-424 (2004).
    • (2004) Trends Endocrinol. Metab. , vol.15 , pp. 418-424
    • Seckl, J.R.1    Walker, B.R.2
  • 153
    • 3242783282 scopus 로고    scopus 로고
    • Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder
    • Young, A. H. et al. Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder. Neuropsychopharmacology 29, 1538-1545 (2004).
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1538-1545
    • Young, A.H.1
  • 154
    • 0034193881 scopus 로고    scopus 로고
    • Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: The first 20 patients treated
    • Zobel, A. W. et al. Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated. J. Psychiatr. Res. 34, 171-181 (2000).
    • (2000) J. Psychiatr. Res. , vol.34 , pp. 171-181
    • Zobel, A.W.1
  • 156
    • 0036752158 scopus 로고    scopus 로고
    • An open label trial of C-1073 (mifepristone) for psychotic major depression
    • Belanoff, J. K. et al. An open label trial of C-1073 (mifepristone) for psychotic major depression. Biol. Psychiatry 52, 386-392 (2002).
    • (2002) Biol. Psychiatry , vol.52 , pp. 386-392
    • Belanoff, J.K.1
  • 157
    • 0026019646 scopus 로고
    • Rapid reversal of acute psychosis in the Gushing syndrome with the cortisol-receptor antagonist mifepristone (RU 486)
    • van der Lely, A. J., Foeken, K., van der Mast, R. C. & Lamberts, S. W. Rapid reversal of acute psychosis in the Gushing syndrome with the cortisol-receptor antagonist mifepristone (RU 486). Ann. Intern. Med. 114, 143-144 (1991).
    • (1991) Ann. Intern. Med. , vol.114 , pp. 143-144
    • Van Der Lely, A.J.1    Foeken, K.2    Van Der Mast, R.C.3    Lamberts, S.W.4
  • 158
    • 0032457031 scopus 로고    scopus 로고
    • Continuous blockade of brain glucocorticoid receptors facilitates spatial learning and memory in rats
    • Oitzl, M. S., Fluttert, M., Sutanto, W. & de Kloet, E. R. Continuous blockade of brain glucocorticoid receptors facilitates spatial learning and memory in rats. Eur J. Neurosci. 10, 3759-3766 (1998).
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 3759-3766
    • Oitzl, M.S.1    Fluttert, M.2    Sutanto, W.3    De Kloet, E.R.4
  • 159
    • 0038565455 scopus 로고    scopus 로고
    • Effect of chronic administration of selective glucocorticoid receptor antagonists on the rat hypothalamic-pituitary-adrenocortical axis
    • Bachmann, C. G., Linthorst, A. C., Holsboer, F. & Reul, J. M. Effect of chronic administration of selective glucocorticoid receptor antagonists on the rat hypothalamic-pituitary-adrenocortical axis. Neuropsychopharmacology 28, 1056-1067 (2003).
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1056-1067
    • Bachmann, C.G.1    Linthorst, A.C.2    Holsboer, F.3    Reul, J.M.4
  • 160
    • 0032895726 scopus 로고    scopus 로고
    • The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety
    • Holsboer, F. The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety. J. Psychiatr. Res. 33, 181-214 (1999).
    • (1999) J. Psychiatr. Res. , vol.33 , pp. 181-214
    • Holsboer, F.1
  • 161
    • 3342984728 scopus 로고    scopus 로고
    • Low-dose cortisol for symptoms of posttraumatic stress disorder
    • Aerni, A. et al. Low-dose cortisol for symptoms of posttraumatic stress disorder. Am. J. Psychiatry 161, 1488-1490 (2004).
    • (2004) Am. J. Psychiatry , vol.161 , pp. 1488-1490
    • Aerni, A.1
  • 162
    • 12144287939 scopus 로고    scopus 로고
    • Stress doses of hydrocortisone, traumatic memories, and symptoms of posttraumatic stress disorder in patients after cardiac surgery: A randomized study
    • Schelling, G. et al. Stress doses of hydrocortisone, traumatic memories, and symptoms of posttraumatic stress disorder in patients after cardiac surgery: a randomized study. Biol. Psychiatry 55, 627-633 (2004).
    • (2004) Biol. Psychiatry , vol.55 , pp. 627-633
    • Schelling, G.1
  • 163
    • 0000432665 scopus 로고    scopus 로고
    • Human stresscopin and stresscopin-related peptide are selective ligands for the type corticotropin-releasing hormone receptor
    • Hsu, S. Y. & Hsueh, A. J. Human stresscopin and stresscopin-related peptide are selective ligands for the type corticotropin-releasing hormone receptor. Nature Med. 7, 605-611 (2001).
    • (2001) Nature Med. , vol.7 , pp. 605-611
    • Hsu, S.Y.1    Hsueh, A.J.2
  • 164
    • 0035956938 scopus 로고    scopus 로고
    • Urocortin II: A member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors
    • Reyes, T. M. et al. Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors. Proc. Natl Acad. Sci. USA 98, 2843-2848 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2843-2848
    • Reyes, T.M.1
  • 165
    • 4644285709 scopus 로고    scopus 로고
    • Corticotropin-releasing factor in brain: A role in activation, arousal, and affect regulation
    • Heinrichs, S. C. & Koob, G. F. Corticotropin-releasing factor in brain: a role in activation, arousal, and affect regulation. J. Pharmacol. Exp. Ther. 311, 427-440 (2004).
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , pp. 427-440
    • Heinrichs, S.C.1    Koob, G.F.2
  • 166
    • 0041324898 scopus 로고    scopus 로고
    • The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: Molecular mechanisms for gene repression
    • De Bosscher, K., Vanden Berghe, W. & Haegeman, G. The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: molecular mechanisms for gene repression. Endocr. Rev. 24, 488-522 (2003).
    • (2003) Endocr. Rev. , vol.24 , pp. 488-522
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3


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