Common phenolic metabolites of flavonoids, but not their unmetabolized precursors, reduce the secretion of vascular cellular adhesion molecules by human endothelial cells

Journal of Nutrition

Volumn 146, Issue 3, 2016, Pages 465-473

  Warner, Emily F ^a   Zhang, Qingzhi ^c   Saki Raheem, K ^c,d   Hagan, David O ^c   O'Connell, Maria A ^b   Kay, Colin D ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^c UNIVERSITY OF ST ANDREWS   (United Kingdom)

^d UNIVERSITY OF WESTMINSTER   (United Kingdom)

Author keywords

Endothelial; Inflammation; Metabolism; Phase II conjugate; Polyphenol; VCAM 1

Indexed keywords

FLAVONOID; ISOVANILLIC ACID; ISOVANILLIC ACID 3 GLUCURONIDE; MESSENGER RNA; POLYPHENOL DERIVATIVE; PROTOCATECHUIC ACID; PROTOCATECHUIC ACID 3 SULFATE; PROTOCATECHUIC ACID 4 SULFATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; HYDROXYBENZOIC ACID DERIVATIVE; PHENOLIC ACID; TUMOR NECROSIS FACTOR;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; METABOLITE; PROTEIN SECRETION; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION; UMBILICAL VEIN ENDOTHELIAL CELL; DRUG EFFECTS; GENETICS; METABOLISM;

FLAVONOIDS; GENE EXPRESSION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROXYBENZOATES; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84960417297     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.115.217943     Document Type: Article

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