Mycophenolic acid attenuates the tumour necrosis factor-α-mediated proinflammatory response in endothelial cells by blocking the MAPK/NF-κB and ROS pathways

European Journal of Clinical Investigation

Volumn 44, Issue 1, 2014, Pages 54-64

  Olejarz, Wioletta ^a   Bryk, Dorota ^a   Zapolska Downar, Danuta ^a   Malecki, Maciej ^a   Stachurska, Anna ^a   Sitkiewicz, Dariusz ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Adhesion molecules; Mitogen activated protein kinases; Mycophenolic acid; Nuclear factor B; Reactive oxygen species

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOCYNIN; DICHLOROFLUORESCEIN; DIPHENYLIODONIUM SALT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MEMBRANE PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYCOPHENOLIC ACID; PYRROLIDINE DITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; AORTA; ARTERY ENDOTHELIUM; ARTICLE; CELL ADHESION ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE EXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ADHERENCE; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VASCULITIS; WESTERN BLOTTING;

ADHESION MOLECULES; MITOGEN-ACTIVATED PROTEIN KINASES; MYCOPHENOLIC ACID; NUCLEAR FACTOR-ΚB; REACTIVE OXYGEN SPECIES;

CELL LINE; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HUMANS; INFLAMMATION; MITOGEN-ACTIVATED PROTEIN KINASES; MYCOPHENOLIC ACID; NF-KAPPA B; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84890793830     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/eci.12191     Document Type: Article

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