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Volumn 2016, Issue , 2016, Pages

Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EMACTUZUMAB; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; TRANSCRIPTION FACTOR SOX; TUMOR NECROSIS FACTOR ALPHA;

EID: 84959530818     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2016/9012369     Document Type: Review
Times cited : (95)

References (166)
  • 1
    • 84896125494 scopus 로고    scopus 로고
    • Evolution of the cancer stem cell model
    • A. Kreso and J. E. Dick, "Evolution of the cancer stem cell model," Cell Stem Cell, vol. 14, no. 3, pp. 275-291, 2014.
    • (2014) Cell Stem Cell , vol.14 , Issue.3 , pp. 275-291
    • Kreso, A.1    Dick, J.E.2
  • 2
    • 84965199448 scopus 로고
    • An address on the value of pathological experiments
    • R. Virchow, "An address on the value of pathological experiments," The BritishMedical Journal, vol. 2, no. 1075, pp. 198-203, 1881.
    • (1881) The BritishMedical Journal , vol.2 , Issue.1075 , pp. 198-203
    • Virchow, R.1
  • 3
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • T. Lapidot, C. Sirard, J. Vormoor et al., "A cell initiating human acute myeloid leukaemia after transplantation into SCID mice," Nature, vol. 367, no. 6464, pp. 645-648, 1994.
    • (1994) Nature , vol.367 , Issue.6464 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3
  • 4
    • 33847052127 scopus 로고    scopus 로고
    • Identification of pancreatic cancer stem cells
    • C. Li, D. G. Heidt, P. Dalerba et al., "Identification of pancreatic cancer stem cells," Cancer Research, vol. 67, no. 3, pp. 1030-1037, 2007.
    • (2007) Cancer Research , vol.67 , Issue.3 , pp. 1030-1037
    • Li, C.1    Heidt, D.G.2    Dalerba, P.3
  • 5
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • P. C. Hermann, S. L. Huber, T. Herrler et al., "Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer," Cell Stem Cell, vol. 1, no. 3, pp. 313-323, 2007.
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3
  • 7
    • 33745198882 scopus 로고    scopus 로고
    • Chemotherapy resistance of glioblastoma stem cells
    • A. Eramo, L. Ricci-Vitiani, A. Zeuner et al., "Chemotherapy resistance of glioblastoma stem cells," Cell Death & Differentiation, vol. 13, no. 7, pp. 1238-1241, 2006.
    • (2006) Cell Death & Differentiation , vol.13 , Issue.7 , pp. 1238-1241
    • Eramo, A.1    Ricci-Vitiani, L.2    Zeuner, A.3
  • 8
    • 84908605558 scopus 로고    scopus 로고
    • Intracellular autofluorescence: A biomarker for epithelial cancer stem cells
    • I. Miranda-Lorenzo, J. Dorado, E. Lonardo et al., "Intracellular autofluorescence: a biomarker for epithelial cancer stem cells," Nature Methods, vol. 11, no. 11, pp. 1161-1169, 2014.
    • (2014) Nature Methods , vol.11 , Issue.11 , pp. 1161-1169
    • Miranda-Lorenzo, I.1    Dorado, J.2    Lonardo, E.3
  • 10
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • C. A. O'Brien, A. Pollett, S. Gallinger, and J. E. Dick, "A human colon cancer cell capable of initiating tumour growth in immunodeficient mice," Nature, vol. 445, no. 7123, pp. 106-110, 2007.
    • (2007) Nature , vol.445 , Issue.7123 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 11
    • 33846095137 scopus 로고    scopus 로고
    • Identification and expansion of human colon-cancer-initiating cells
    • L. Ricci-Vitiani, D. G. Lombardi, E. Pilozzi et al., "Identification and expansion of human colon-cancer-initiating cells," Nature, vol. 445, no. 7123, pp. 111-115, 2007.
    • (2007) Nature , vol.445 , Issue.7123 , pp. 111-115
    • Ricci-Vitiani, L.1    Lombardi, D.G.2    Pilozzi, E.3
  • 12
    • 33645026803 scopus 로고    scopus 로고
    • Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
    • L. Patrawala, T. Calhoun, R. Schneider-Broussard et al., "Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells," Oncogene, vol. 25, no. 12, pp. 1696-1708, 2006.
    • (2006) Oncogene , vol.25 , Issue.12 , pp. 1696-1708
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3
  • 13
    • 38349165576 scopus 로고    scopus 로고
    • Identification of cells initiating human melanomas
    • T. Schatton, G. F. Murphy, N. Y. Frank et al., "Identification of cells initiating human melanomas," Nature, vol. 451, no. 7176, pp. 345-349, 2008.
    • (2008) Nature , vol.451 , Issue.7176 , pp. 345-349
    • Schatton, T.1    Murphy, G.F.2    Frank, N.Y.3
  • 15
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • S. K. Singh, C. Hawkins, I. D. Clarke et al., "Identification of human brain tumour initiating cells," Nature, vol. 432, no. 7015, pp. 396-401, 2004.
    • (2004) Nature , vol.432 , Issue.7015 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 17
    • 77956214387 scopus 로고    scopus 로고
    • Tumor-initiating cells are rare in many human tumors
    • K. Ishizawa, Z. A. Rasheed, R. Karisch et al., "Tumor-initiating cells are rare in many human tumors," Cell Stem Cell, vol. 7, no. 3, pp. 279-282, 2010.
    • (2010) Cell Stem Cell , vol.7 , Issue.3 , pp. 279-282
    • Ishizawa, K.1    Rasheed, Z.A.2    Karisch, R.3
  • 18
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • T. Reya, S. J. Morrison, M. F. Clarke, and I. L. Weissman, "Stem cells, cancer, and cancer stem cells," Nature, vol. 414, no. 6859, pp. 105-111, 2001.
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 19
    • 79955681163 scopus 로고    scopus 로고
    • The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse
    • A. Merlos-Suárez, F. M. Barriga, P. Jung et al., "The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse," Cell Stem Cell, vol. 8, no. 5, pp. 511-524, 2011.
    • (2011) Cell Stem Cell , vol.8 , Issue.5 , pp. 511-524
    • Merlos-Suárez, A.1    Barriga, F.M.2    Jung, P.3
  • 20
    • 73149110562 scopus 로고    scopus 로고
    • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    • S. Pece, D. Tosoni, S. Confalonieri et al., "Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content," Cell, vol. 140, no. 1, pp. 62-73, 2010.
    • (2010) Cell , vol.140 , Issue.1 , pp. 62-73
    • Pece, S.1    Tosoni, D.2    Confalonieri, S.3
  • 21
    • 77951639324 scopus 로고    scopus 로고
    • Colon cancer stem cells: Promise of targeted therapy
    • M. Todaro, M. G. Francipane, J. P. Medema, and G. Stassi, "Colon cancer stem cells: promise of targeted therapy," Gastroenterology, vol. 138, no. 6, pp. 2151-2162, 2010.
    • (2010) Gastroenterology , vol.138 , Issue.6 , pp. 2151-2162
    • Todaro, M.1    Francipane, M.G.2    Medema, J.P.3    Stassi, G.4
  • 22
    • 84941599105 scopus 로고    scopus 로고
    • Stemcelllike gene expression signature identified in ionizing radiationtreated cancer cells
    • J.H. Bae, S.H. Park, J. H. Yang, K. Yang, and J.M. Yi, "Stemcelllike gene expression signature identified in ionizing radiationtreated cancer cells," Gene, vol. 572, no. 2, pp. 285-291, 2015.
    • (2015) Gene , vol.572 , Issue.2 , pp. 285-291
    • Bae, J.H.1    Park, S.H.2    Yang, J.H.3    Yang, K.4    Yi, J.M.5
  • 23
    • 84873084388 scopus 로고    scopus 로고
    • Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer
    • A. Kreso, C. A. O'Brien, P. van Galen et al., "Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer," Science, vol. 339, no. 6119, pp. 543-548, 2013.
    • (2013) Science , vol.339 , Issue.6119 , pp. 543-548
    • Kreso, A.1    O'Brien, C.A.2    Van Galen, P.3
  • 24
    • 84941194629 scopus 로고    scopus 로고
    • Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells
    • S. Dingwall, J. B. Lee, B. Guezguez et al., "Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells," Oncotarget, vol. 6, no. 26, pp. 22258-22269, 2015.
    • (2015) Oncotarget , vol.6 , Issue.26 , pp. 22258-22269
    • Dingwall, S.1    Lee, J.B.2    Guezguez, B.3
  • 25
    • 84947073205 scopus 로고    scopus 로고
    • Embryonic stem cell-related protein L1TD1 is required for cell viability, neurosphere formation, and chemoresistance in medulloblastoma
    • M. C. Santos, P. B. Silva, C. O. Rodini et al., "Embryonic stem cell-related protein L1TD1 is required for cell viability, neurosphere formation, and chemoresistance in medulloblastoma," Stem Cells and Development, vol. 24, no. 22, pp. 2700-2708, 2015.
    • (2015) Stem Cells and Development , vol.24 , Issue.22 , pp. 2700-2708
    • Santos, M.C.1    Silva, P.B.2    Rodini, C.O.3
  • 27
    • 84856078085 scopus 로고    scopus 로고
    • A family business: Stem cell progeny join the niche to regulate homeostasis
    • Y.-C. Hsu and E. Fuchs, "A family business: stem cell progeny join the niche to regulate homeostasis," Nature Reviews Molecular Cell Biology, vol. 13, no. 2, pp. 103-114, 2012.
    • (2012) Nature Reviews Molecular Cell Biology , vol.13 , Issue.2 , pp. 103-114
    • Hsu, Y.-C.1    Fuchs, E.2
  • 28
    • 84924249260 scopus 로고    scopus 로고
    • The cancer stem cell niche: Howessential is the niche in regulating stemness of tumor cells?
    • V. Plaks, N. Kong, Z. Werb, and V. Plaks, "The cancer stem cell niche: howessential is the niche in regulating stemness of tumor cells?" Cell Stem Cell, vol. 16, no. 3, pp. 225-238, 2015.
    • (2015) Cell Stem Cell , vol.16 , Issue.3 , pp. 225-238
    • Plaks, V.1    Kong, N.2    Werb, Z.3    Plaks, V.4
  • 29
    • 84866755869 scopus 로고    scopus 로고
    • New insights into pancreatic cancer biology
    • M. Hidalgo, "New insights into pancreatic cancer biology," Annals of Oncology, vol. 23, supplement 10, pp. x135-x138, 2012.
    • (2012) Annals of Oncology , vol.23 , pp. x135-x138
    • Hidalgo, M.1
  • 30
    • 84858590826 scopus 로고    scopus 로고
    • Accessories to the crime: Functions of cells recruited to the tumor microenvironment
    • D. Hanahan and L. M. Coussens, "Accessories to the crime: functions of cells recruited to the tumor microenvironment," Cancer Cell, vol. 21, no. 3, pp. 309-322, 2012.
    • (2012) Cancer Cell , vol.21 , Issue.3 , pp. 309-322
    • Hanahan, D.1    Coussens, L.M.2
  • 31
    • 80053401068 scopus 로고    scopus 로고
    • Breast cancer stem cells, cytokine networks, and the tumor microenvironment
    • H. Korkaya, S. Liu, and M. S. Wicha, "Breast cancer stem cells, cytokine networks, and the tumor microenvironment," The Journal of Clinical Investigation, vol. 121, no. 10, pp. 3804-3809, 2011.
    • (2011) The Journal of Clinical Investigation , vol.121 , Issue.10 , pp. 3804-3809
    • Korkaya, H.1    Liu, S.2    Wicha, M.S.3
  • 32
    • 84866784798 scopus 로고    scopus 로고
    • Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
    • D. G. DeNardo, D. J. Brennan, E. Rexhepaj et al., "Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy," Cancer Discovery, vol. 1, no. 1, pp. 54-67, 2011.
    • (2011) Cancer Discovery , vol.1 , Issue.1 , pp. 54-67
    • DeNardo, D.G.1    Brennan, D.J.2    Rexhepaj, E.3
  • 33
    • 84860342715 scopus 로고    scopus 로고
    • Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness
    • E. Lonardo, J. Frias-Aldeguer, P. C. Hermann, and C. Heeschen, "Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness," Cell Cycle, vol. 11, no. 7, pp. 1282-1290, 2012.
    • (2012) Cell Cycle , vol.11 , Issue.7 , pp. 1282-1290
    • Lonardo, E.1    Frias-Aldeguer, J.2    Hermann, P.C.3    Heeschen, C.4
  • 34
    • 63149088164 scopus 로고    scopus 로고
    • Trophic macrophages in development and disease
    • J. W. Pollard, "Trophic macrophages in development and disease," Nature Reviews Immunology, vol. 9, no. 4, pp. 259-270, 2009.
    • (2009) Nature Reviews Immunology , vol.9 , Issue.4 , pp. 259-270
    • Pollard, J.W.1
  • 35
    • 84887155324 scopus 로고    scopus 로고
    • Cancer stem cell dynamics in tumor progression and metastasis: Is the microenvironment to blame?
    • E. Fessler, F. E. Dijkgraaf, F. De Sousa E Melo, and J. P. Medema, "Cancer stem cell dynamics in tumor progression and metastasis: is the microenvironment to blame?" Cancer Letters, vol. 341, no. 1, pp. 97-104, 2013.
    • (2013) Cancer Letters , vol.341 , Issue.1 , pp. 97-104
    • Fessler, E.1    Dijkgraaf, F.E.2    De Sousa, F.3    Melo, E.4    Medema, J.P.5
  • 36
    • 80755141299 scopus 로고    scopus 로고
    • Nodal/activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy
    • E. Lonardo, P. C. Hermann, M.-T. Mueller et al., "Nodal/activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy," Cell Stem Cell, vol. 9, no. 5, pp. 433-446, 2011.
    • (2011) Cell Stem Cell , vol.9 , Issue.5 , pp. 433-446
    • Lonardo, E.1    Hermann, P.C.2    Mueller, M.-T.3
  • 37
    • 78751522709 scopus 로고    scopus 로고
    • Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks
    • S. Liu, C. Ginestier, S. J. Ou et al., "Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks," Cancer Research, vol. 71, no. 2, pp. 614-624, 2011.
    • (2011) Cancer Research , vol.71 , Issue.2 , pp. 614-624
    • Liu, S.1    Ginestier, C.2    Ou, S.J.3
  • 38
    • 84866307571 scopus 로고    scopus 로고
    • Cancer-stimulatedmesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling
    • H.-J. Li, F. Reinhardt, H. R. Herschman, and R. A. Weinberg, "Cancer-stimulatedmesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling," Cancer Discovery, vol. 2, no. 9, pp. 840-855, 2012.
    • (2012) Cancer Discovery , vol.2 , Issue.9 , pp. 840-855
    • Li, H.-J.1    Reinhardt, F.2    Herschman, H.R.3    Weinberg, R.A.4
  • 39
    • 84855425160 scopus 로고    scopus 로고
    • Interactions between cancer stem cells and their niche govern metastatic colonization
    • I. Malanchi, A. Santamaria-Martínez, E. Susanto et al., "Interactions between cancer stem cells and their niche govern metastatic colonization," Nature, vol. 481, no. 7379, pp. 85-89, 2012.
    • (2012) Nature , vol.481 , Issue.7379 , pp. 85-89
    • Malanchi, I.1    Santamaria-Martínez, A.2    Susanto, E.3
  • 40
    • 84897927173 scopus 로고    scopus 로고
    • Hepatic stellate cells secreted hepatocyte growth factor contributes to the chemoresistance of hepatocellular carcinoma
    • G. Yu, Y. Jing, X. Kou et al., "Hepatic stellate cells secreted hepatocyte growth factor contributes to the chemoresistance of hepatocellular carcinoma," PLoS ONE, vol. 8, no. 9, Article ID e73312, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.9
    • Yu, G.1    Jing, Y.2    Kou, X.3
  • 41
    • 80053030114 scopus 로고    scopus 로고
    • The cancer stem cell niche-there goes the neighborhood?
    • S. M. Cabarcas, L. A. Mathews, and W. L. Farrar, "The cancer stem cell niche-there goes the neighborhood?" International Journal of Cancer, vol. 129, no. 10, pp. 2315-2327, 2011.
    • (2011) International Journal of Cancer , vol.129 , Issue.10 , pp. 2315-2327
    • Cabarcas, S.M.1    Mathews, L.A.2    Farrar, W.L.3
  • 42
    • 84904406680 scopus 로고    scopus 로고
    • Tumor-associatedmacrophages: From mechanisms to therapy
    • R. Noy and J.W. Pollard, "Tumor-associatedmacrophages: from mechanisms to therapy," Immunity, vol. 41, no. 1, pp.49-61, 2014.
    • (2014) Immunity , vol.41 , Issue.1 , pp. 49-61
    • Noy, R.1    Pollard, J.W.2
  • 43
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumourassociated macrophages in tumour progression: Implications for new anticancer therapies
    • L. Bingle, N. J. Brown, and C. E. Lewis, "The role of tumourassociated macrophages in tumour progression: implications for new anticancer therapies," Journal of Pathology, vol. 196, no. 3, pp. 254-265, 2002.
    • (2002) Journal of Pathology , vol.196 , Issue.3 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 44
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • B.-Z. Qian and J. W. Pollard, "Macrophage diversity enhances tumor progression and metastasis," Cell, vol. 141, no. 1, pp. 39-51, 2010.
    • (2010) Cell , vol.141 , Issue.1 , pp. 39-51
    • Qian, B.-Z.1    Pollard, J.W.2
  • 45
    • 77349101042 scopus 로고    scopus 로고
    • Features of the dendritic cell lineage
    • R. M. Steinman and J. Idoyaga, "Features of the dendritic cell lineage," Immunological Reviews, vol. 234, no. 1, pp. 5-17, 2010.
    • (2010) Immunological Reviews , vol.234 , Issue.1 , pp. 5-17
    • Steinman, R.M.1    Idoyaga, J.2
  • 46
    • 83455203338 scopus 로고    scopus 로고
    • Identification and manipulation of tumor associated macrophages in human cancers
    • M. Heusinkveld and S. H. van der Burg, "Identification and manipulation of tumor associated macrophages in human cancers," Journal of Translational Medicine, vol. 9, article 216, 2011.
    • (2011) Journal of Translational Medicine , vol.9
    • Heusinkveld, M.1    Burg Der Van, S.H.2
  • 47
    • 84904394690 scopus 로고    scopus 로고
    • Macrophage activation and polarization: Nomenclature and experimental guidelines
    • P. J. Murray, J. E. Allen, S. K. Biswas et al., "Macrophage activation and polarization: nomenclature and experimental guidelines," Immunity, vol. 41, no. 1, pp. 14-20, 2014.
    • (2014) Immunity , vol.41 , Issue.1 , pp. 14-20
    • Murray, P.J.1    Allen, J.E.2    Biswas, S.K.3
  • 48
    • 84891358332 scopus 로고    scopus 로고
    • Macrophages and CSF-1: Implications for development and beyond
    • C. V. Jones and S. D. Ricardo, "Macrophages and CSF-1: implications for development and beyond," Organogenesis, vol. 9, no. 4, pp. 249-260, 2013.
    • (2013) Organogenesis , vol.9 , Issue.4 , pp. 249-260
    • Jones, C.V.1    Ricardo, S.D.2
  • 49
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: In vivo veritas
    • A. Sica and A. Mantovani, "Macrophage plasticity and polarization: in vivo veritas," Journal of Clinical Investigation, vol. 122, no. 3, pp. 787-795, 2012.
    • (2012) Journal of Clinical Investigation , vol.122 , Issue.3 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 50
    • 77953268611 scopus 로고    scopus 로고
    • Alternative activation of macrophages: Mechanism and functions
    • S. Gordon and F. O. Martinez, "Alternative activation of macrophages: mechanism and functions," Immunity, vol. 32, no. 5, pp. 593-604, 2010.
    • (2010) Immunity , vol.32 , Issue.5 , pp. 593-604
    • Gordon, S.1    Martinez, F.O.2
  • 51
    • 84952629667 scopus 로고    scopus 로고
    • Phagocytes as corrupted policemen in cancer-related inflammation
    • E. Bonavita, M. R. Galdiero, S. Jaillon et al., "Phagocytes as corrupted policemen in cancer-related inflammation," Advances in Cancer Research, vol. 128, pp. 141-171, 2015.
    • (2015) Advances in Cancer Research , vol.128 , pp. 141-171
    • Bonavita, E.1    Galdiero, M.R.2    Jaillon, S.3
  • 52
    • 84922689090 scopus 로고    scopus 로고
    • PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer
    • E. Bonavita, S. Gentile, M. Rubino et al., "PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer," Cell, vol. 160, no. 4, pp. 700-714, 2015.
    • (2015) Cell , vol.160 , Issue.4 , pp. 700-714
    • Bonavita, E.1    Gentile, S.2    Rubino, M.3
  • 53
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
    • S. K. Biswas and A. Mantovani, "Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm," Nature Immunology, vol. 11, no. 10, pp. 889-896, 2010.
    • (2010) Nature Immunology , vol.11 , Issue.10 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 54
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • D. M. Mosser and J. P. Edwards, "Exploring the full spectrum of macrophage activation," Nature Reviews Immunology, vol. 8, no. 12, pp. 958-969, 2008.
    • (2008) Nature Reviews Immunology , vol.8 , Issue.12 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 55
    • 80051627660 scopus 로고    scopus 로고
    • M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells
    • M. Heusinkveld, P. J. de Vos van Steenwijk, R. Goedemans et al., "M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells," The Journal of Immunology, vol. 187, no. 3, pp. 1157-1165, 2011.
    • (2011) The Journal of Immunology , vol.187 , Issue.3 , pp. 1157-1165
    • Heusinkveld, M.1    De Vos Van Steenwijk, P.J.2    Goedemans, R.3
  • 56
    • 67650485985 scopus 로고    scopus 로고
    • Alternative activation of macrophages: An immunologic functional perspective
    • F. O. Martinez, L. Helming, and S. Gordon, "Alternative activation of macrophages: an immunologic functional perspective," Annual Review of Immunology, vol. 27, pp. 451-483, 2009.
    • (2009) Annual Review of Immunology , vol.27 , pp. 451-483
    • Martinez, F.O.1    Helming, L.2    Gordon, S.3
  • 57
    • 82555181278 scopus 로고    scopus 로고
    • Tumorassociated macrophages in breast cancer: Distinct subsets, distinct functions
    • D. Laoui, K. Movahedi, E. Van Overmeire et al., "Tumorassociated macrophages in breast cancer: distinct subsets, distinct functions," International Journal of Developmental Biology, vol. 55, no. 7-9, pp. 861-867, 2011.
    • (2011) International Journal of Developmental Biology , vol.55 , Issue.7-9 , pp. 861-867
    • Laoui, D.1    Movahedi, K.2    Van Overmeire, E.3
  • 58
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
    • F. O. Martinez, S. Gordon, M. Locati, and A. Mantovani, "Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression, "The Journal of Immunology, vol. 177, no. 10, pp. 7303-7311, 2006.
    • (2006) The Journal of Immunology , vol.177 , Issue.10 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 59
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigmfor polarizedM2mononuclear phagocytes
    • A. Mantovani, S. Sozzani, M. Locati, P. Allavena, and A. Sica, "Macrophage polarization: tumor-associated macrophages as a paradigmfor polarizedM2mononuclear phagocytes," Trends in Immunology, vol. 23, no. 11, pp. 549-555, 2002.
    • (2002) Trends in Immunology , vol.23 , Issue.11 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 60
    • 84941336575 scopus 로고    scopus 로고
    • Tim-3 fosters HCC development by enhancing TGF-β-mediated alternative activation of macrophages
    • W. Yan, X. Liu, H. Ma et al., "Tim-3 fosters HCC development by enhancing TGF-β-mediated alternative activation of macrophages," Gut, vol. 64, no. 10, pp. 1593-1604, 2015.
    • (2015) Gut , vol.64 , Issue.10 , pp. 1593-1604
    • Yan, W.1    Liu, X.2    Ma, H.3
  • 61
    • 76149146398 scopus 로고    scopus 로고
    • IL-4 induces cathepsin protease activity in tumor-associatedmacrophages to promote cancer growth and invasion
    • V. Gocheva, H.-W. Wang, B. B. Gadea et al., "IL-4 induces cathepsin protease activity in tumor-associatedmacrophages to promote cancer growth and invasion," Genes and Development, vol. 24, no. 3, pp. 241-255, 2010.
    • (2010) Genes and Development , vol.24 , Issue.3 , pp. 241-255
    • Gocheva, V.1    Wang, H.-W.2    Gadea, B.B.3
  • 62
    • 0036177290 scopus 로고    scopus 로고
    • Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer
    • Y. Nagakawa, T. Aoki, K. Kasuya, A. Tsuchida, and Y. Koyanagi, "Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer," Pancreas, vol. 24, no. 2, pp. 169-178, 2002.
    • (2002) Pancreas , vol.24 , Issue.2 , pp. 169-178
    • Nagakawa, Y.1    Aoki, T.2    Kasuya, K.3    Tsuchida, A.4    Koyanagi, Y.5
  • 63
    • 80053640221 scopus 로고    scopus 로고
    • Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression
    • R. Wang, J. Zhang, S. Chen et al., "Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression," Lung Cancer, vol. 74, no. 2, pp. 188-196, 2011.
    • (2011) Lung Cancer , vol.74 , Issue.2 , pp. 188-196
    • Wang, R.1    Zhang, J.2    Chen, S.3
  • 64
    • 84939459740 scopus 로고    scopus 로고
    • Human breast cancer cells educate macrophages toward the M2 activation status
    • S. Sousa, R. Brion, M. Lintunen et al., "Human breast cancer cells educate macrophages toward the M2 activation status," Breast Cancer Research, vol. 17, no. 1, article 101, 2015.
    • (2015) Breast Cancer Research , vol.17 , Issue.1
    • Sousa, S.1    Brion, R.2    Lintunen, M.3
  • 65
    • 84867635011 scopus 로고    scopus 로고
    • Macrophages promote fibroblast growth factor receptor-driven tumor cell migration and invasion in a CXCR2-dependent manner
    • L. R. Bohrer and K. L. Schwertfeger, "Macrophages promote fibroblast growth factor receptor-driven tumor cell migration and invasion in a CXCR2-dependent manner," Molecular Cancer Research, vol. 10, no. 10, pp. 1294-1305, 2012.
    • (2012) Molecular Cancer Research , vol.10 , Issue.10 , pp. 1294-1305
    • Bohrer, L.R.1    Schwertfeger, K.L.2
  • 66
    • 84904308396 scopus 로고    scopus 로고
    • Tumor-associated macrophages promote the metastatic potential of thyroid papillary cancer by releasing CXCL8
    • W. Fang, L. Ye, L. Shen et al., "Tumor-associated macrophages promote the metastatic potential of thyroid papillary cancer by releasing CXCL8," Carcinogenesis, vol. 35, no. 8, pp. 1780-1787, 2014.
    • (2014) Carcinogenesis , vol.35 , Issue.8 , pp. 1780-1787
    • Fang, W.1    Ye, L.2    Shen, L.3
  • 67
    • 84862879740 scopus 로고    scopus 로고
    • Tumor-associated microglia/ macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway
    • X.-Z. Ye, S.-L. Xu, Y.-H. Xin et al., "Tumor-associated microglia/ macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway, "TheJournal of Immunology, vol. 189, no. 1, pp. 444-453, 2012.
    • (2012) TheJournal of Immunology , vol.189 , Issue.1 , pp. 444-453
    • Ye, X.-Z.1    Xu, S.-L.2    Xin, Y.-H.3
  • 68
    • 84898769460 scopus 로고    scopus 로고
    • TGF-beta1-ROSATM- CREB signaling axis in macrophage mediated migration of human breast cancerMCF7 cells
    • R. Singh, B. S. Shankar, and K. B. Sainis, "TGF-beta1-ROSATM- CREB signaling axis in macrophage mediated migration of human breast cancerMCF7 cells," Cellular Signalling, vol. 26, no. 7, pp. 1604-1615, 2014.
    • (2014) Cellular Signalling , vol.26 , Issue.7 , pp. 1604-1615
    • Singh, R.1    Shankar, B.S.2    Sainis, K.B.3
  • 69
    • 84873703218 scopus 로고    scopus 로고
    • Tumor-produced versican V1 enhances hCAP18/LL-37 expression in macrophages through activation of TLR2 and vitamin D3 signaling to promote ovarian cancer progression in vitro
    • D. Li, X. Wang, J.-L. Wu et al., "Tumor-produced versican V1 enhances hCAP18/LL-37 expression in macrophages through activation of TLR2 and vitamin D3 signaling to promote ovarian cancer progression in vitro," PLoS ONE, vol. 8, no. 2, Article ID e56616, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.2
    • Li, D.1    Wang, X.2    Wu, J.-L.3
  • 70
    • 84954363411 scopus 로고    scopus 로고
    • Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment
    • B. Sainz Jr., S. Alcala, E. Garcia et al., "Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment," Gut, vol. 64, no. 12, pp. 1921-1935, 2015.
    • (2015) Gut , vol.64 , Issue.12 , pp. 1921-1935
    • Sainz, B.1    Alcala, S.2    Garcia, E.3
  • 71
    • 33845767868 scopus 로고    scopus 로고
    • Macrophages regulate the angiogenic switch in a mouse model of breast cancer
    • E. Y. Lin, J.-F. Li, L. Gnatovskiy et al., "Macrophages regulate the angiogenic switch in a mouse model of breast cancer," Cancer Research, vol. 66, no. 23, pp. 11238-11246, 2006.
    • (2006) Cancer Research , vol.66 , Issue.23 , pp. 11238-11246
    • Lin, E.Y.1    Li, J.-F.2    Gnatovskiy, L.3
  • 72
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • C. Murdoch, M. Muthana, S. B. Coffelt, and C. E. Lewis, "The role of myeloid cells in the promotion of tumour angiogenesis," Nature Reviews Cancer, vol. 8, no. 8, pp. 618-631, 2008.
    • (2008) Nature Reviews Cancer , vol.8 , Issue.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 73
    • 47949096781 scopus 로고    scopus 로고
    • Cancerrelated inflammation
    • A. Mantovani, P. Allavena, A. Sica, and F. Balkwill, "Cancerrelated inflammation," Nature, vol. 454, no. 7203, pp. 436-444, 2008.
    • (2008) Nature , vol.454 , Issue.7203 , pp. 436-444
    • Mantovani, A.1    Allavena, P.2    Sica, A.3    Balkwill, F.4
  • 74
    • 33645991795 scopus 로고    scopus 로고
    • Tumourassociated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • A. Sica, T. Schioppa, A. Mantovani, and P. Allavena, "Tumourassociated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy," European Journal of Cancer, vol. 42, no. 6, pp. 717-727, 2006.
    • (2006) European Journal of Cancer , vol.42 , Issue.6 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 76
    • 84958057302 scopus 로고    scopus 로고
    • Cancer stem cells and tumor-associated macrophages: A roadmap for multitargeting strategies
    • C. Raggi, H. S. Mousa, M. Correnti, A. Sica, and P. Invernizzi, "Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies," Oncogene, 2015.
    • (2015) Oncogene
    • Raggi, C.1    Mousa, H.S.2    Correnti, M.3    Sica, A.4    Invernizzi, P.5
  • 77
    • 77954922985 scopus 로고    scopus 로고
    • Stem cells in cancer: Instigators and propagators?
    • M. R. Alison, S. Islam, and N. A. Wright, "Stem cells in cancer: instigators and propagators?" Journal of Cell Science, vol. 123, part 14, pp. 2357-2368, 2010.
    • (2010) Journal of Cell Science , vol.123 , pp. 2357-2368
    • Alison, M.R.1    Islam, S.2    Wright, N.A.3
  • 78
    • 80053531658 scopus 로고    scopus 로고
    • Regulation of cancer stem cells by cytokine networks: Attacking cancer's inflammatory roots
    • H. Korkaya, S. Liu, and M. S. Wicha, "Regulation of cancer stem cells by cytokine networks: attacking cancer's inflammatory roots," Clinical Cancer Research, vol. 17, no. 19, pp. 6125-6129, 2011.
    • (2011) Clinical Cancer Research , vol.17 , Issue.19 , pp. 6125-6129
    • Korkaya, H.1    Liu, S.2    Wicha, M.S.3
  • 79
    • 0036085164 scopus 로고    scopus 로고
    • Epidemiological and clinical aspects of nonsteroidal anti-inflammatory drugs and cancer risks
    • E. M. Moran, "Epidemiological and clinical aspects of nonsteroidal anti-inflammatory drugs and cancer risks," Journal of Environmental Pathology, Toxicology and Oncology, vol. 21, no. 2, pp. 193-201, 2002.
    • (2002) Journal of Environmental Pathology, Toxicology and Oncology , vol.21 , Issue.2 , pp. 193-201
    • Moran, E.M.1
  • 80
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: Linking inflammation and immunity to cancer development and progression
    • M. Karin and F. R. Greten, "NF-kappaB: linking inflammation and immunity to cancer development and progression," Nature Reviews Immunology, vol. 5, no. 10, pp. 749-759, 2005.
    • (2005) Nature Reviews Immunology , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 81
    • 4043088499 scopus 로고    scopus 로고
    • IKKβ links inflammation and tumorigenesis in a mouse model of colitisassociated cancer
    • F. R. Greten, L. Eckmann, T. F. Greten et al., "IKKβ links inflammation and tumorigenesis in a mouse model of colitisassociated cancer," Cell, vol. 118, no. 3, pp. 285-296, 2004.
    • (2004) Cell , vol.118 , Issue.3 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 82
    • 58649101347 scopus 로고    scopus 로고
    • Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
    • J. Bollrath, T. J. Phesse, V. A. von Burstin et al., "gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis," Cancer Cell, vol. 15, no. 2, pp. 91-102, 2009.
    • (2009) Cancer Cell , vol.15 , Issue.2 , pp. 91-102
    • Bollrath, J.1    Phesse, T.J.2    Von Burstin, V.A.3
  • 83
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • F. Colotta, P. Allavena, A. Sica, C. Garlanda, and A. Mantovani, "Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability," Carcinogenesis, vol. 30, no. 7, pp. 1073-1081, 2009.
    • (2009) Carcinogenesis , vol.30 , Issue.7 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 84
    • 58649119388 scopus 로고    scopus 로고
    • Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment
    • M. Kortylewski, H. Xin, M. Kujawski et al., "Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment," Cancer Cell, vol. 15, no. 2, pp. 114-123, 2009.
    • (2009) Cancer Cell , vol.15 , Issue.2 , pp. 114-123
    • Kortylewski, M.1    Xin, H.2    Kujawski, M.3
  • 85
    • 77950558347 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland
    • H. L. LaMarca, A. P. Visbal, C. J. Creighton et al., "CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland," STEM CELLS, vol. 28, no. 3, pp. 535-544, 2010.
    • (2010) STEM CELLS , vol.28 , Issue.3 , pp. 535-544
    • LaMarca, H.L.1    Visbal, A.P.2    Creighton, C.J.3
  • 86
    • 21244472975 scopus 로고    scopus 로고
    • IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
    • S. Maeda, H. Kamata, J.-L. Luo, H. Leffert, and M. Karin, "IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis," Cell, vol. 121, no. 7, pp. 977-990, 2005.
    • (2005) Cell , vol.121 , Issue.7 , pp. 977-990
    • Maeda, S.1    Kamata, H.2    Luo, J.-L.3    Leffert, H.4    Karin, M.5
  • 87
    • 70350778443 scopus 로고    scopus 로고
    • An epigenetic switch involving NF-κB, Lin28, Let-7MicroRNA, and IL6 links inflammation to celltransformation
    • D. Iliopoulos, H. A. Hirsch, and K. Struhl, "An epigenetic switch involving NF-κB, Lin28, Let-7MicroRNA, and IL6 links inflammation to celltransformation," Cell, vol. 139, no. 4, pp. 693-706, 2009.
    • (2009) Cell , vol.139 , Issue.4 , pp. 693-706
    • Iliopoulos, D.1    Hirsch, H.A.2    Struhl, K.3
  • 88
    • 0032734761 scopus 로고    scopus 로고
    • Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha
    • S. Y. Song, M. Gannon, M. K. Washington et al., "Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha," Gastroenterology, vol. 117, no. 6, pp. 1416-1426, 1999.
    • (1999) Gastroenterology , vol.117 , Issue.6 , pp. 1416-1426
    • Song, S.Y.1    Gannon, M.2    Washington, M.K.3
  • 89
    • 84884236200 scopus 로고    scopus 로고
    • Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs
    • G.-Y. Liou, H. Döppler, B. Necela et al., "Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs," The Journal of Cell Biology, vol. 202, no. 3, pp. 563-577, 2013.
    • (2013) The Journal of Cell Biology , vol.202 , Issue.3 , pp. 563-577
    • Liou, G.-Y.1    Döppler, H.2    Necela, B.3
  • 90
    • 33847419143 scopus 로고    scopus 로고
    • Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice
    • C. Guerra, A. J. Schuhmacher, M. Cañamero et al., "Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice," Cancer Cell, vol. 11, no. 3, pp. 291-302, 2007.
    • (2007) Cancer Cell , vol.11 , Issue.3 , pp. 291-302
    • Guerra, C.1    Schuhmacher, A.J.2    Cañamero, M.3
  • 91
    • 84922341040 scopus 로고    scopus 로고
    • MutantKRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions
    • G.-Y. Liou, H. Döppler, B. Necela et al., "MutantKRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions," Cancer Discovery, vol. 5, no. 1, pp. 52-63, 2015.
    • (2015) Cancer Discovery , vol.5 , Issue.1 , pp. 52-63
    • Liou, G.-Y.1    Döppler, H.2    Necela, B.3
  • 92
    • 34249882777 scopus 로고    scopus 로고
    • Foxo3a is essential for maintenance of the hematopoietic stem cell pool
    • K. Miyamoto, K. Y. Araki, K. Naka et al., "Foxo3a is essential for maintenance of the hematopoietic stem cell pool," Cell Stem Cell, vol. 1, no. 1, pp. 101-112, 2007.
    • (2007) Cell Stem Cell , vol.1 , Issue.1 , pp. 101-112
    • Miyamoto, K.1    Araki, K.Y.2    Naka, K.3
  • 93
    • 64749093574 scopus 로고    scopus 로고
    • Association of reactive oxygen species levels and radioresistance in cancer stem cells
    • M. Diehn, R.W. Cho, N. A. Lobo et al., "Association of reactive oxygen species levels and radioresistance in cancer stem cells," Nature, vol. 458, no. 7239, pp. 780-783, 2009.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 780-783
    • Diehn, M.1    Cho, R.W.2    Lobo, N.A.3
  • 94
    • 33845904383 scopus 로고    scopus 로고
    • The response of CD24 -/low/CD44 + breast cancer-initiating cells to radiation
    • T. M. Phillips, W. H. McBride, and F. Pajonk, "The response of CD24 -/low/CD44 + breast cancer-initiating cells to radiation," Journal of the National Cancer Institute, vol. 98, no. 24, pp. 1777-1785, 2006.
    • (2006) Journal of the National Cancer Institute , vol.98 , Issue.24 , pp. 1777-1785
    • Phillips, T.M.1    McBride, W.H.2    Pajonk, F.3
  • 95
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • F. Balkwill and A. Mantovani, "Inflammation and cancer: back to Virchow?" The Lancet, vol. 357, no. 9255, pp. 539-545, 2001.
    • (2001) The Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 96
    • 36849012237 scopus 로고    scopus 로고
    • Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas
    • S. P. Gao, K. G. Mark, K. Leslie et al., "Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas," Journal of Clinical Investigation, vol. 117, no. 12, pp. 3846-3856, 2007.
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.12 , pp. 3846-3856
    • Gao, S.P.1    Mark, K.G.2    Leslie, K.3
  • 97
    • 58149232586 scopus 로고    scopus 로고
    • The interleukin-8 pathway in cancer
    • D. J. J. Waugh and C. Wilson, "The interleukin-8 pathway in cancer," Clinical Cancer Research, vol. 14, no. 21, pp. 6735-6741, 2008.
    • (2008) Clinical Cancer Research , vol.14 , Issue.21 , pp. 6735-6741
    • Waugh, D.J.J.1    Wilson, C.2
  • 98
    • 76649113726 scopus 로고    scopus 로고
    • CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
    • C. Ginestier, S. Liu, M. E. Diebel et al., "CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts," Journal of Clinical Investigation, vol. 120, no. 2, pp. 485-497, 2010.
    • (2010) Journal of Clinical Investigation , vol.120 , Issue.2 , pp. 485-497
    • Ginestier, C.1    Liu, S.2    Diebel, M.E.3
  • 99
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-κB-a pivotal transcription factor in chronic inflammatory diseases
    • P. J. Barnes and M. Karin, "Nuclear factor-κB-a pivotal transcription factor in chronic inflammatory diseases," TheNew England Journal ofMedicine, vol. 336, no. 15, pp. 1066-1071, 1997.
    • (1997) The New England Journal of Medicine , vol.336 , Issue.15 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 100
    • 84913580379 scopus 로고    scopus 로고
    • Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells
    • S. Wan, E. Zhao, I. Kryczek et al., "Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells," Gastroenterology, vol. 147, no. 6, pp. 1393-1404, 2014.
    • (2014) Gastroenterology , vol.147 , Issue.6 , pp. 1393-1404
    • Wan, S.1    Zhao, E.2    Kryczek, I.3
  • 101
    • 84873468174 scopus 로고    scopus 로고
    • Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses
    • J. B. Mitchem, D. J. Brennan, B. L. Knolhoff et al., "Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses," Cancer Research, vol. 73, no. 3, pp. 1128-1141, 2013.
    • (2013) Cancer Research , vol.73 , Issue.3 , pp. 1128-1141
    • Mitchem, J.B.1    Brennan, D.J.2    Knolhoff, B.L.3
  • 102
    • 44149100809 scopus 로고    scopus 로고
    • High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas
    • S. Le Gouvello, S. Bastuji-Garin, N. Aloulou et al., "High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas," Gut, vol. 57, no. 6, pp. 772-779, 2008.
    • (2008) Gut , vol.57 , Issue.6 , pp. 772-779
    • Le Gouvello, S.1    Bastuji-Garin, S.2    Aloulou, N.3
  • 104
    • 48849103649 scopus 로고    scopus 로고
    • Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing
    • K. S. Sfanos, T. C. Bruno, C. H. Maris et al., "Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing," Clinical Cancer Research, vol. 14, no. 11, pp. 3254-3261, 2008.
    • (2008) Clinical Cancer Research , vol.14 , Issue.11 , pp. 3254-3261
    • Sfanos, K.S.1    Bruno, T.C.2    Maris, C.H.3
  • 105
    • 63849307580 scopus 로고    scopus 로고
    • IL-17 expression by breast-cancer-associatedmacrophages: IL-17 promotes invasiveness of breast cancer cell lines
    • X. Zhu, L. A. Mulcahy, R. A. A. Mohammed et al., "IL-17 expression by breast-cancer-associatedmacrophages: IL-17 promotes invasiveness of breast cancer cell lines," Breast Cancer Research, vol. 10, no. 6, article R95, 2008.
    • (2008) Breast Cancer Research , vol.10 , Issue.6
    • Zhu, X.1    Mulcahy, L.A.2    Mohammed, R.A.A.3
  • 106
    • 84890522862 scopus 로고    scopus 로고
    • Interleukin-17 produced by tumor microenvironment promotes self-renewal of CD133+ cancer stem-like cells in ovarian cancer
    • T. Xiang, H. Long, L. He et al., "Interleukin-17 produced by tumor microenvironment promotes self-renewal of CD133+ cancer stem-like cells in ovarian cancer," Oncogene, vol. 34, no. 2, pp. 165-176, 2015.
    • (2015) Oncogene , vol.34 , Issue.2 , pp. 165-176
    • Xiang, T.1    Long, H.2    He, L.3
  • 107
    • 84931050133 scopus 로고    scopus 로고
    • Monocytes andmacrophages, implications for breast cancer migration and stem cell-like activity and treatment
    • R. Ward, A. H. Sims, A. Lee et al., "Monocytes andmacrophages, implications for breast cancer migration and stem cell-like activity and treatment," Oncotarget, vol. 6, no. 16, pp. 14687-14699, 2015.
    • (2015) Oncotarget , vol.6 , Issue.16 , pp. 14687-14699
    • Ward, R.1    Sims, A.H.2    Lee, A.3
  • 108
    • 20444436815 scopus 로고    scopus 로고
    • Macrophages promote the invasion of breast carcinoma cells via a colonystimulating factor-1/epidermal growth factor paracrine loop
    • S. Goswami, E. Sahai, J. B. Wyckoff et al., "Macrophages promote the invasion of breast carcinoma cells via a colonystimulating factor-1/epidermal growth factor paracrine loop," Cancer Research, vol. 65, no. 12, pp. 5278-5283, 2005.
    • (2005) Cancer Research , vol.65 , Issue.12 , pp. 5278-5283
    • Goswami, S.1    Sahai, E.2    Wyckoff, J.B.3
  • 109
    • 84874291853 scopus 로고    scopus 로고
    • Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway
    • J. Yang, D. Liao, C. Chen et al., "Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway," STEM CELLS, vol. 31, no. 2, pp. 248-258, 2013.
    • (2013) STEM CELLS , vol.31 , Issue.2 , pp. 248-258
    • Yang, J.1    Liao, D.2    Chen, C.3
  • 110
    • 84858341630 scopus 로고    scopus 로고
    • Sox2 expression in breast tumours and activation in breast cancer stem cells
    • O. Leis, A. Eguiara, E. Lopez-Arribillaga et al., "Sox2 expression in breast tumours and activation in breast cancer stem cells," Oncogene, vol. 31, no. 11, pp. 1354-1365, 2012.
    • (2012) Oncogene , vol.31 , Issue.11 , pp. 1354-1365
    • Leis, O.1    Eguiara, A.2    Lopez-Arribillaga, E.3
  • 111
    • 84878983107 scopus 로고    scopus 로고
    • Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming
    • N. Tiwari, V. K. Tiwari, L. Waldmeier et al., "Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming," Cancer Cell, vol. 23, no. 6, pp. 768-783, 2013.
    • (2013) Cancer Cell , vol.23 , Issue.6 , pp. 768-783
    • Tiwari, N.1    Tiwari, V.K.2    Waldmeier, L.3
  • 112
    • 78651454089 scopus 로고    scopus 로고
    • EZH2promotes expansion of breast tumor initiating cells through activation of RAF1-β- catenin signaling
    • C.-J. Chang, J.-Y. Yang, W. Xia et al., "EZH2promotes expansion of breast tumor initiating cells through activation of RAF1-β- catenin signaling," Cancer Cell, vol. 19, no. 1, pp. 86-100, 2011.
    • (2011) Cancer Cell , vol.19 , Issue.1 , pp. 86-100
    • Chang, C.-J.1    Yang, J.-Y.2    Xia, W.3
  • 113
    • 84908485098 scopus 로고    scopus 로고
    • A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages
    • H. Lu, K. R. Clauser, W. L. Tam et al., "A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages," Nature Cell Biology, vol. 16, no. 11, pp. 1105-1117, 2014.
    • (2014) Nature Cell Biology , vol.16 , Issue.11 , pp. 1105-1117
    • Lu, H.1    Clauser, K.R.2    Tam, W.L.3
  • 114
    • 67449147143 scopus 로고    scopus 로고
    • Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms
    • M. Jinushi, M. Sato, A. Kanamoto et al., "Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms," The Journal of Experimental Medicine, vol. 206, no. 6, pp. 1317-1326, 2009.
    • (2009) The Journal of Experimental Medicine , vol.206 , Issue.6 , pp. 1317-1326
    • Jinushi, M.1    Sato, M.2    Kanamoto, A.3
  • 115
    • 84923068676 scopus 로고    scopus 로고
    • Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
    • W. Zhou, S. Q. Ke, Z. Huang et al., "Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth," Nature Cell Biology, vol. 17, no. 2, pp. 170-182, 2015.
    • (2015) Nature Cell Biology , vol.17 , Issue.2 , pp. 170-182
    • Zhou, W.1    Ke, S.Q.2    Huang, Z.3
  • 116
    • 84918523966 scopus 로고    scopus 로고
    • ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells
    • B. Sainz Jr., B. Martín, M. Tatari, C. Heeschen, and S. Guerra, "ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells," Cancer Research, vol. 74, no. 24, pp. 7309-7320, 2014.
    • (2014) Cancer Research , vol.74 , Issue.24 , pp. 7309-7320
    • Sainz, B.1    Martín, B.2    Tatari, M.3    Heeschen, C.4    Guerra, S.5
  • 117
    • 84860476707 scopus 로고    scopus 로고
    • MFGE8 released by apoptotic endothelial cells triggers antiinflammatory macrophage reprogramming
    • M.-J. Brissette, S. Lepage, A.-S. Lamonde et al., "MFGE8 released by apoptotic endothelial cells triggers antiinflammatory macrophage reprogramming," PLoS ONE, vol. 7, no. 4, Article ID e36368, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.4
    • Brissette, M.-J.1    Lepage, S.2    Lamonde, A.-S.3
  • 118
    • 0035911221 scopus 로고    scopus 로고
    • Colonystimulating factor 1 promotes progression of mammary tumors to malignancy
    • E.Y. Lin, A.V. Nguyen, R. G. Russell, and J.W. Pollard, "Colonystimulating factor 1 promotes progression of mammary tumors to malignancy, "The Journal of Experimental Medicine, vol. 193, no. 6, pp. 727-740, 2001.
    • (2001) The Journal of Experimental Medicine , vol.193 , Issue.6 , pp. 727-740
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4
  • 119
    • 84859817610 scopus 로고    scopus 로고
    • Adjuvant effect of IV clodronate on the delay of bone metastasis in high-risk prostate cancer patients: A prospective study
    • P. Rodrigues, F. O. Hering, and A. Meller, "Adjuvant effect of IV clodronate on the delay of bone metastasis in high-risk prostate cancer patients: a prospective study," Cancer Research and Treatment, vol. 43, no. 4, pp. 231-235, 2011.
    • (2011) Cancer Research and Treatment , vol.43 , Issue.4 , pp. 231-235
    • Rodrigues, P.1    Hering, F.O.2    Meller, A.3
  • 120
    • 77954229219 scopus 로고    scopus 로고
    • Depletion of tumorassociated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects
    • W. Zhang, X.-D. Zhu, H.-C. Sun et al., "Depletion of tumorassociated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects," Clinical Cancer Research, vol. 16, no. 13, pp. 3420-3430, 2010.
    • (2010) Clinical Cancer Research , vol.16 , Issue.13 , pp. 3420-3430
    • Zhang, W.1    Zhu, X.-D.2    Sun, H.-C.3
  • 121
    • 84880270290 scopus 로고    scopus 로고
    • Identification of a population of blood circulating tumor cells frombreast cancer patients that initiates metastasis in a xenograft assay
    • I. Baccelli, A. Schneeweiss, S. Riethdorf et al., "Identification of a population of blood circulating tumor cells frombreast cancer patients that initiates metastasis in a xenograft assay," Nature Biotechnology, vol. 31, no. 6, pp. 539-544, 2013.
    • (2013) Nature Biotechnology , vol.31 , Issue.6 , pp. 539-544
    • Baccelli, I.1    Schneeweiss, A.2    Riethdorf, S.3
  • 122
    • 84936888406 scopus 로고    scopus 로고
    • MIR-25 modulates invasiveness and dissemination of human prostate cancer cells via regulation of αv- and α 6-integrin expression
    • E. Zoni, G. van der Horst, A. F. van de Merbel et al., "miR-25 modulates invasiveness and dissemination of human prostate cancer cells via regulation of αv- and α 6-integrin expression," Cancer Research, vol. 75, no. 11, pp. 2326-2336, 2015.
    • (2015) Cancer Research , vol.75 , Issue.11 , pp. 2326-2336
    • Zoni, E.1    Horst Der G.Van2    Merbel De Van, A.F.3
  • 123
    • 84905819148 scopus 로고    scopus 로고
    • Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer
    • C. L. Hodgkinson, C. J. Morrow, Y. Li et al., "Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer," Nature Medicine, vol. 20, no. 8, pp. 897-903, 2014.
    • (2014) Nature Medicine , vol.20 , Issue.8 , pp. 897-903
    • Hodgkinson, C.L.1    Morrow, C.J.2    Li, Y.3
  • 124
    • 84867058802 scopus 로고    scopus 로고
    • LOXL2 in epithelial cell plasticity and tumor progression
    • A. Cano, P. G. Santamaría, and G. Moreno-Bueno, "LOXL2 in epithelial cell plasticity and tumor progression," Future Oncology, vol. 8, no. 9, pp. 1095-1108, 2012.
    • (2012) Future Oncology , vol.8 , Issue.9 , pp. 1095-1108
    • Cano, A.1    Santamaría, P.G.2    Moreno-Bueno, G.3
  • 125
    • 80052708567 scopus 로고    scopus 로고
    • Breast cancer growth and metastasis: Interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition
    • N. Takebe, R. Q. Warren, and S. P. Ivy, "Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition," Breast Cancer Research, vol. 13, no. 3, p. 211, 2011.
    • (2011) Breast Cancer Research , vol.13 , Issue.3 , pp. 211
    • Takebe, N.1    Warren, R.Q.2    Ivy, S.P.3
  • 126
    • 84906053870 scopus 로고    scopus 로고
    • Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma
    • Q.-M. Fan, Y.-Y. Jing, G.-F. Yu et al., "Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma," Cancer Letters, vol. 352, no. 2, pp. 160-168, 2014.
    • (2014) Cancer Letters , vol.352 , Issue.2 , pp. 160-168
    • Fan, Q.-M.1    Jing, Y.-Y.2    Yu, G.-F.3
  • 127
    • 84900335537 scopus 로고    scopus 로고
    • A positive feedback loop between mesenchymal-like cancer cells and macrophages is essential to breast cancer metastasis
    • S. Su, Q. Liu, J. Chen et al., "A positive feedback loop between mesenchymal-like cancer cells and macrophages is essential to breast cancer metastasis," Cancer Cell, vol. 25, no. 5, pp. 605-620, 2014.
    • (2014) Cancer Cell , vol.25 , Issue.5 , pp. 605-620
    • Su, S.1    Liu, Q.2    Chen, J.3
  • 128
    • 84896694386 scopus 로고    scopus 로고
    • Tumor-associated macrophages promote oral cancer progression through activation of the Axl signaling pathway
    • C.-H. Lee, S.-Y. Liu, K.-C. Chou et al., "Tumor-associated macrophages promote oral cancer progression through activation of the Axl signaling pathway," Annals of Surgical Oncology, vol. 21, no. 3, pp. 1031-1037, 2014.
    • (2014) Annals of Surgical Oncology , vol.21 , Issue.3 , pp. 1031-1037
    • Lee, C.-H.1    Liu, S.-Y.2    Chou, K.-C.3
  • 129
    • 84879663836 scopus 로고    scopus 로고
    • M2-polarized tumorassociated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL- 10 signaling pathway
    • C.-Y. Liu, J.-Y. Xu, X.-Y. Shi et al., "M2-polarized tumorassociated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL- 10 signaling pathway," Laboratory Investigation, vol. 93, no. 7, pp. 844-854, 2013.
    • (2013) Laboratory Investigation , vol.93 , Issue.7 , pp. 844-854
    • Liu, C.-Y.1    Xu, J.-Y.2    Shi, X.-Y.3
  • 130
    • 84862823626 scopus 로고    scopus 로고
    • Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors
    • A.-K. Bonde, V. Tischler, S. Kumar, A. Soltermann, and R. A. Schwendener, "Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors," BMC Cancer, vol. 12, article 35, 2012.
    • (2012) BMC Cancer , vol.12
    • Bonde, A.-K.1    Tischler, V.2    Kumar, S.3    Soltermann, A.4    Schwendener, R.A.5
  • 131
    • 33646591223 scopus 로고    scopus 로고
    • Macrophage activation increases the invasive properties of hepatoma cells by destabilization of the adherens junction
    • C.-Y. Lin, C.-J. Lin, K.-H. Chen, J.-C. Wu, S.-H. Huang, and S.-M. Wang, "Macrophage activation increases the invasive properties of hepatoma cells by destabilization of the adherens junction," FEBS Letters, vol. 580, no. 13, pp. 3042-3050, 2006.
    • (2006) FEBS Letters , vol.580 , Issue.13 , pp. 3042-3050
    • Lin, C.-Y.1    Lin, C.-J.2    Chen, K.-H.3    Wu, J.-C.4    Huang, S.-H.5    Wang, S.-M.6
  • 132
    • 84938922128 scopus 로고    scopus 로고
    • STAT3 activation mediates epithelial-to-mesenchymal transition in human hepatocellular carcinoma cells
    • C. H. Zhang, F. L. Guo, G. L. Xu et al., "STAT3 activation mediates epithelial-to-mesenchymal transition in human hepatocellular carcinoma cells," Hepatogastroenterology, vol. 61, no. 132, pp. 1082-1089, 2014.
    • (2014) Hepatogastroenterology , vol.61 , Issue.132 , pp. 1082-1089
    • Zhang, C.H.1    Guo, F.L.2    Xu, G.L.3
  • 133
    • 84930615596 scopus 로고    scopus 로고
    • Exposure of tumorassociated macrophages to apoptotic MCF-7 cells promotes breast cancer growth and metastasis
    • N. Zhou, Y. Zhang, X. Zhang et al., "Exposure of tumorassociated macrophages to apoptotic MCF-7 cells promotes breast cancer growth and metastasis," International Journal of Molecular Sciences, vol. 16, no. 6, pp. 11966-11982, 2015.
    • (2015) International Journal of Molecular Sciences , vol.16 , Issue.6 , pp. 11966-11982
    • Zhou, N.1    Zhang, Y.2    Zhang, X.3
  • 134
    • 79961074770 scopus 로고    scopus 로고
    • Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells
    • M. Jinushi, S. Chiba, H. Yoshiyama et al., "Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells," Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 30, pp. 12425-12430, 2011.
    • (2011) Proceedings of the National Academy of Sciences of the United States of America , vol.108 , Issue.30 , pp. 12425-12430
    • Jinushi, M.1    Chiba, S.2    Yoshiyama, H.3
  • 135
    • 43049165453 scopus 로고    scopus 로고
    • The epithelialmesenchymal transition generates cells with properties of stem cells
    • S. A. Mani, W. Guo, M.-J. Liao et al., "The epithelialmesenchymal transition generates cells with properties of stem cells," Cell, vol. 133, no. 4, pp. 704-715, 2008.
    • (2008) Cell , vol.133 , Issue.4 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.-J.3
  • 136
    • 84857052013 scopus 로고    scopus 로고
    • Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression
    • S. B. Krantz, M. A. Shields, S. Dangi-Garimella, H. G. Munshi, and D. J. Bentrem, "Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression," Journal of Surgical Research, vol. 173, no. 1, pp. 105-112, 2012.
    • (2012) Journal of Surgical Research , vol.173 , Issue.1 , pp. 105-112
    • Krantz, S.B.1    Shields, M.A.2    Dangi-Garimella, S.3    Munshi, H.G.4    Bentrem, D.J.5
  • 137
    • 84881557402 scopus 로고    scopus 로고
    • Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro
    • A. Dovas, A. Patsialou, A. S. Harney, J. Condeelis, and D. Cox, "Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro," Journal of Microscopy, vol. 251, no. 3, pp. 261-269, 2013.
    • (2013) Journal of Microscopy , vol.251 , Issue.3 , pp. 261-269
    • Dovas, A.1    Patsialou, A.2    Harney, A.S.3    Condeelis, J.4    Cox, D.5
  • 138
    • 79951825045 scopus 로고    scopus 로고
    • Fusion between intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming
    • A. E. Powell, E. C. Anderson, P. S. Davies et al., "Fusion between intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming," Cancer Research, vol. 71, no. 4, pp. 1497-1505, 2011.
    • (2011) Cancer Research , vol.71 , Issue.4 , pp. 1497-1505
    • Powell, A.E.1    Anderson, E.C.2    Davies, P.S.3
  • 139
    • 84874059035 scopus 로고    scopus 로고
    • DNA synthesis is required for reprogrammingmediated by stemcell fusion
    • T. Tsubouchi, J. Soza-Ried, K. Brown et al., "DNA synthesis is required for reprogrammingmediated by stemcell fusion," Cell, vol. 152, no. 4, pp. 873-883, 2013.
    • (2013) Cell , vol.152 , Issue.4 , pp. 873-883
    • Tsubouchi, T.1    Soza-Ried, J.2    Brown, K.3
  • 140
    • 84893590802 scopus 로고    scopus 로고
    • Should EMT of cancer cells be understood as epithelial-myeloid transition?
    • H.M. Schramm, "Should EMT of cancer cells be understood as epithelial-myeloid transition?" Journal of Cancer, vol. 5, no. 2, pp. 125-132, 2014.
    • (2014) Journal of Cancer , vol.5 , Issue.2 , pp. 125-132
    • Schramm, H.M.1
  • 141
    • 42549167207 scopus 로고    scopus 로고
    • Fusion of tumour cells with bone marrow-derived cells: A unifying explanation for metastasis
    • J. M. Pawelek and A. K. Chakraborty, "Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasis," Nature Reviews Cancer, vol. 8, no. 5, pp. 377-386, 2008.
    • (2008) Nature Reviews Cancer , vol.8 , Issue.5 , pp. 377-386
    • Pawelek, J.M.1    Chakraborty, A.K.2
  • 142
    • 56849131881 scopus 로고    scopus 로고
    • The cancer cell- leukocyte fusion theory of metastasis
    • chapter 10, Academic Press, New York, NY, USA
    • J. M. Pawelek and A. K. Chakraborty, "The cancer cell- leukocyte fusion theory of metastasis," in Advances in Cancer Research, vol. 101, chapter 10, pp. 397-444, Academic Press, New York, NY, USA, 2008.
    • (2008) Advances in Cancer Research , vol.101 , pp. 397-444
    • Pawelek, J.M.1    Chakraborty, A.K.2
  • 143
    • 84942848393 scopus 로고    scopus 로고
    • Macrophage-tumor cell fusions from peripheral blood of melanoma patients
    • G. A. Clawson, G. L. Matters, P. Xin et al., "Macrophage-tumor cell fusions from peripheral blood of melanoma patients," PLoS ONE, vol. 10, no. 8, Article IDe0134320, 2015.
    • (2015) PLoS ONE , vol.10 , Issue.8
    • Clawson, G.A.1    Matters, G.L.2    Xin, P.3
  • 144
    • 84879469812 scopus 로고    scopus 로고
    • A melanoma brain metastasis with a donor-patient hybrid genome following bone marrow transplantation: First evidence for fusion in human cancer
    • R. Lazova, G. S. LaBerge, E. Duvall et al., "A melanoma brain metastasis with a donor-patient hybrid genome following bone marrow transplantation: first evidence for fusion in human cancer," PLoS ONE, vol. 8, no. 6, Article ID e66731, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.6
    • Lazova, R.1    LaBerge, G.S.2    Duvall, E.3
  • 146
    • 0031655802 scopus 로고    scopus 로고
    • Multistep nature of metastatic inefficiency: Dormancy of solitary cells after successful extravasation and limited survival of early micrometastases
    • K. J. Luzzi, I. C. MacDonald, E. E. Schmidt et al., "Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases," The American Journal of Pathology, vol. 153, no. 3, pp. 865-873, 1998.
    • (1998) The American Journal of Pathology , vol.153 , Issue.3 , pp. 865-873
    • Luzzi, K.J.1    MacDonald, I.C.2    Schmidt, E.E.3
  • 147
    • 0035138203 scopus 로고    scopus 로고
    • Apoptosis: An early event in metastatic inefficiency
    • C.W. Wong, A. Lee, L. Shientag et al., "Apoptosis: an early event in metastatic inefficiency," Cancer Research, vol. 61, no. 1, pp. 333-338, 2001.
    • (2001) Cancer Research , vol.61 , Issue.1 , pp. 333-338
    • Wong, C.W.1    Lee, A.2    Shientag, L.3
  • 148
    • 84896113460 scopus 로고    scopus 로고
    • Metastatic stem cells: Sources, niches, and vital pathways
    • T. Oskarsson, E. Batlle, and J. Massagué, "Metastatic stem cells: sources, niches, and vital pathways," Cell Stem Cell, vol. 14, no. 3, pp. 306-321, 2014.
    • (2014) Cell Stem Cell , vol.14 , Issue.3 , pp. 306-321
    • Oskarsson, T.1    Batlle, E.2    Massagué, J.3
  • 149
    • 84892619683 scopus 로고    scopus 로고
    • Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts
    • S. Liu, Y. Cong, D. Wang et al., "Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts," StemCell Reports, vol. 2, no. 1, pp. 78-91, 2014.
    • (2014) StemCell Reports , vol.2 , Issue.1 , pp. 78-91
    • Liu, S.1    Cong, Y.2    Wang, D.3
  • 150
    • 33750306612 scopus 로고    scopus 로고
    • Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
    • M. Balic, H. Lin, L. Young et al., "Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype," Clinical Cancer Research, vol. 12, no. 19, pp. 5615-5621, 2006.
    • (2006) Clinical Cancer Research , vol.12 , Issue.19 , pp. 5615-5621
    • Balic, M.1    Lin, H.2    Young, L.3
  • 151
    • 84883818940 scopus 로고    scopus 로고
    • Circulating tumor cells
    • V. Plaks, C.D. Koopman, and Z. Werb, "Circulating tumor cells," Science, vol. 341, no. 6151, pp. 1186-1188, 2013.
    • (2013) Science , vol.341 , Issue.6151 , pp. 1186-1188
    • Plaks, V.1    Koopman, C.D.2    Werb, Z.3
  • 152
    • 68749109536 scopus 로고    scopus 로고
    • A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth
    • B. Qian, Y. Deng, J. H. Im et al., "A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth," PLoS ONE, vol. 4, no. 8, Article ID e6562, 2009.
    • (2009) PLoS ONE , vol.4 , Issue.8
    • Qian, B.1    Deng, Y.2    Im, J.H.3
  • 153
    • 28644432204 scopus 로고    scopus 로고
    • VEGFR1- positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
    • R. N. Kaplan, R. D. Riba, S. Zacharoulis et al., "VEGFR1- positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche," Nature, vol. 438, no. 7069, pp. 820-827, 2005.
    • (2005) Nature , vol.438 , Issue.7069 , pp. 820-827
    • Kaplan, R.N.1    Riba, R.D.2    Zacharoulis, S.3
  • 154
    • 84876784448 scopus 로고    scopus 로고
    • Circulating fibrocytes prepare the lung for cancer metastasis by recruiting Ly-6C+ monocytes via CCL2
    • H. W. van Deventer, D. A. Palmieri, Q. P. Wu, E. C. McCook, and J. S. Serody, "Circulating fibrocytes prepare the lung for cancer metastasis by recruiting Ly-6C+ monocytes via CCL2," The Journal of Immunology, vol. 190, no. 9, pp. 4861-4867, 2013.
    • (2013) The Journal of Immunology , vol.190 , Issue.9 , pp. 4861-4867
    • Van Deventer, H.W.1    Palmieri, D.A.2    Wu, Q.P.3    McCook, E.C.4    Serody, J.S.5
  • 155
    • 84859305668 scopus 로고    scopus 로고
    • Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice
    • A. M. Gil-Bernabé, Š. Ferjančič, M. Tlalka et al., "Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice," Blood, vol. 119, no. 13, pp. 3164-3175, 2012.
    • (2012) Blood , vol.119 , Issue.13 , pp. 3164-3175
    • Gil-Bernabé, A.M.1    Ferjančič, Š.2    Tlalka, M.3
  • 156
    • 84930170395 scopus 로고    scopus 로고
    • Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
    • B. Costa-Silva, N. M. Aiello, A. J. Ocean et al., "Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver," Nature Cell Biology, vol. 17, no. 6, pp. 816-826, 2015.
    • (2015) Nature Cell Biology , vol.17 , Issue.6 , pp. 816-826
    • Costa-Silva, B.1    Aiello, N.M.2    Ocean, A.J.3
  • 158
    • 84873597334 scopus 로고    scopus 로고
    • Role of macrophage targeting in the antitumor activity of trabectedin
    • G. Germano, R. Frapolli, C. Belgiovine et al., "Role of macrophage targeting in the antitumor activity of trabectedin," Cancer Cell, vol. 23, no. 2, pp. 249-262, 2013.
    • (2013) Cancer Cell , vol.23 , Issue.2 , pp. 249-262
    • Germano, G.1    Frapolli, R.2    Belgiovine, C.3
  • 159
    • 84902546715 scopus 로고    scopus 로고
    • Targeting tumorassociated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
    • C. H. Ries, M. A. Cannarile, S. Hoves et al., "Targeting tumorassociated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy," Cancer Cell, vol. 25, no. 6, pp.846-859, 2014.
    • (2014) Cancer Cell , vol.25 , Issue.6 , pp. 846-859
    • Ries, C.H.1    Cannarile, M.A.2    Hoves, S.3
  • 160
    • 84880080588 scopus 로고    scopus 로고
    • Human antimacrophage migration inhibitory factor antibodies inhibit growth of human prostate cancer cells in vitro and in vivo
    • F. Hussain, M. Freissmuth, D. Völkel et al., "Human antimacrophage migration inhibitory factor antibodies inhibit growth of human prostate cancer cells in vitro and in vivo," Molecular Cancer Therapeutics, vol. 12, no. 7, pp. 1223-1234, 2013.
    • (2013) Molecular Cancer Therapeutics , vol.12 , Issue.7 , pp. 1223-1234
    • Hussain, F.1    Freissmuth, M.2    Völkel, D.3
  • 161
    • 84901277245 scopus 로고    scopus 로고
    • Cancer stemlike cells derived from chemoresistant tumors have a unique capacity to prime tumorigenic myeloid cells
    • T. Yamashina, M. Baghdadi, A. Yoneda et al., "Cancer stemlike cells derived from chemoresistant tumors have a unique capacity to prime tumorigenic myeloid cells," Cancer Research, vol. 74, no. 10, pp. 2698-2709, 2014.
    • (2014) Cancer Research , vol.74 , Issue.10 , pp. 2698-2709
    • Yamashina, T.1    Baghdadi, M.2    Yoneda, A.3
  • 162
    • 84941955997 scopus 로고    scopus 로고
    • Inhibition of CD47 effectively targets pancreatic cancer stem cells via dual mechanisms
    • M. Cioffi, S. Trabulo, M. Hidalgo et al., "Inhibition of CD47 effectively targets pancreatic cancer stem cells via dual mechanisms," Clinical Cancer Research, vol. 21, no. 10, pp. 2325-2337, 2015.
    • (2015) Clinical Cancer Research , vol.21 , Issue.10 , pp. 2325-2337
    • Cioffi, M.1    Trabulo, S.2    Hidalgo, M.3
  • 163
    • 84903318466 scopus 로고    scopus 로고
    • Blockade of CD47- mediated cathepsin S/protease-activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma
    • T. K.-W. Lee, V. C.-H. Cheung, P. Lu et al., "Blockade of CD47- mediated cathepsin S/protease-activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma," Hepatology, vol. 60, no. 1, pp. 179-191, 2014.
    • (2014) Hepatology , vol.60 , Issue.1 , pp. 179-191
    • Lee, T.K.-W.1    Cheung, V.C.-H.2    Lu, P.3
  • 164
    • 59249086198 scopus 로고    scopus 로고
    • Functions and molecularmechanisms of the CD47-SIRPα signalling pathway
    • T. Matozaki, Y. Murata, H. Okazawa, and H. Ohnishi, "Functions and molecularmechanisms of the CD47-SIRPα signalling pathway," Trends in Cell Biology, vol. 19, no. 2, pp. 72-80, 2009.
    • (2009) Trends in Cell Biology , vol.19 , Issue.2 , pp. 72-80
    • Matozaki, T.1    Murata, Y.2    Okazawa, H.3    Ohnishi, H.4
  • 165
    • 69549114870 scopus 로고    scopus 로고
    • Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
    • K. S. Chan, I. Espinosa, M. Chao et al., "Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells," Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 33, pp. 14016-14021, 2009.
    • (2009) Proceedings of the National Academy of Sciences of the United States of America , vol.106 , Issue.33 , pp. 14016-14021
    • Chan, K.S.1    Espinosa, I.2    Chao, M.3
  • 166
    • 67650632683 scopus 로고    scopus 로고
    • CD47 is an adverse prognostic factor and therapeutic antibody target on human acutemyeloid leukemia stem cells
    • R. Majeti, M. P. Chao, A. A. Alizadeh et al., "CD47 is an adverse prognostic factor and therapeutic antibody target on human acutemyeloid leukemia stem cells," Cell, vol. 138, no. 2, pp. 286-299, 2009.
    • (2009) Cell , vol.138 , Issue.2 , pp. 286-299
    • Majeti, R.1    Chao, M.P.2    Alizadeh, A.A.3


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