Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine egfr/stat3/sox-2 signaling pathway

Stem Cells

Volumn 31, Issue 2, 2013, Pages 248-258

  Yang, Jian ^a   Liao, Debbie ^b   Chen, Cong ^c   Liu, Yan ^d   Chuang, Tsung Hsien ^d   Xiang, Rong ^a   Markowitz, Dorothy ^b   Reisfeld, Ralph A ^b   Luo, Yunping ^b,c  

^a NANKAI UNIVERSITY   (China)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c Beijing Union Medical School   (China)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Breast cancer; Cancer stem cells; Side population cells; STAT; Stem cell microenvironment interactions; Transcription factors

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; BETA CATENIN; BREAST CANCER RESISTANCE PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; NERVE CELL ADHESION MOLECULE; OCTAMER TRANSCRIPTION FACTOR 4; STAT3 PROTEIN; STEM CELL ANTIGEN 1; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER GROWTH; CANCER RESISTANCE; CANCER STEM CELL; CELL CONTACT; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE ACTIVATION; MOUSE; NONHUMAN; PARACRINE SIGNALING; PHENOTYPE; PROTEIN EXPRESSION; TUMOR ASSOCIATED LEUKOCYTE; UPREGULATION;

ANIMALS; ANTIGENS, LY; APOPTOSIS; ATP-BINDING CASSETTE TRANSPORTERS; CELL COMMUNICATION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; IMIDAZOLES; MACROPHAGES; MAMMARY NEOPLASMS, ANIMAL; MEMBRANE PROTEINS; MICE; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; OLEANOLIC ACID; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; STAT3 TRANSCRIPTION FACTOR; TYRPHOSTINS;

EID: 84874291853     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1281     Document Type: Article

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