Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

Nature Cell Biology

Volumn 17, Issue 6, 2015, Pages 816-826

  Costa Silva, Bruno ^a   Aiello, Nicole M ^b   Ocean, Allyson J ^c   Singh, Swarnima ^a   Zhang, Haiying ^a   Thakur, Basant Kumar ^a,d   Becker, Annette ^a   Hoshino, Ayuko ^a   Mark, Milica Tešić ^e   Molina, Henrik ^e   Xiang, Jenny ^a   Zhang, Tuo ^a   Theilen, Till Martin ^a   García Santos, Guillermo ^a   Williams, Caitlin ^a   Ararso, Yonathan ^a   Huang, Yujie ^a   Rodrigues, Gonçalo ^a,f   Shen, Tang Long ^g   Labori, Knut Jørgen ^h   Lothe, Inger Marie Bowitz ^h   Kure, Elin H ^h   Hernandez, Jonathan ⁱ   Doussot, Alexandre ⁱ   Ebbesen, Saya H ^a   Grandgenett, Paul M ^j   Hollingsworth, Michael A ^j   Jain, Maneesh ^k   Mallya, Kavita ^k   Batra, Surinder K ^k   Jarnagin, William R ⁱ   Schwartz, Robert E ^a   Matei, Irina ^a   Peinado, Héctor ^a,l   Stanger, Ben Z ^b   Bromberg, Jacqueline ⁱ   Lyden, David ^a,i   more..

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^d HANNOVER MEDICAL SCHOOL   (Germany)

^e ROCKEFELLER UNIVERSITY   (United States)

^f UNIVERSITY OF PORTO   (Portugal)

^g NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^h OSLO UNIVERSITY HOSPITAL   (Norway)

ⁱ MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^j UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^k UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^l Centro Nacional de Investigaciones Oncológicas   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; MACROPHAGE MIGRATION INHIBITION FACTOR; PLATELET DERIVED GROWTH FACTOR; TENASCIN; TRANSFORMING GROWTH FACTOR BETA; VITRONECTIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CANCER PROGNOSIS; CANCER STAGING; CELL ACTIVATION; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL INFILTRATION; CELL MIGRATION; CELL POPULATION; CELL TRANSPORT; CONTROLLED STUDY; CTGF GENE; DOWN REGULATION; EDN GENE; EXOSOME; FIBROGENESIS; GENE; GENE EXPRESSION REGULATION; HUMAN; IGF GENE; KUPFFER CELL; LIVER METASTASIS; MOUSE; MYOFIBROBLAST; NONHUMAN; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PDGF GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; TGF BETA GENE; TUMOR VOLUME; UPREGULATION; ANIMAL; BIOSYNTHESIS; BONE MARROW CELL; C57BL MOUSE; CELL MOTION; CYTOLOGY; FEMALE; GENETICS; HEPATIC STELLATE CELL; IMMUNOLOGY; KNOCKOUT MOUSE; LIVER; LIVER TUMOR; MACROPHAGE; METABOLISM; NUCLEOTIDE SEQUENCE; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; PRECANCER; RNA INTERFERENCE; SECONDARY; SECRETION (PROCESS); SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

MUS;

ANIMALS; BASE SEQUENCE; BONE MARROW CELLS; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; CELL MOVEMENT; EXOSOMES; FEMALE; FIBRONECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATIC STELLATE CELLS; HUMANS; LIVER; LIVER NEOPLASMS; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PANCREATIC NEOPLASMS; PRECANCEROUS CONDITIONS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84930170395     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3169     Document Type: Article

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