Gastrodin Ameliorates Oxidative Stress and Proinflammatory Response in Nonalcoholic Fatty Liver Disease through the AMPK/Nrf2 Pathway

Phytotherapy Research

Volumn 30, Issue 3, 2016, Pages 402-411

  Qu, Li Li ^a   Yu, Bin ^b   Li, Zheng ^b   Jiang, Wen Xiao ^c   Jiang, Jian Dong ^a   Kong, Wei Jia ^b  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^c EMORY UNIVERSITY   (United States)

Author keywords

AMP activated protein kinase; gastrodin; hepatic steatosis; Nrf2; proinflammatory cytokines

Indexed keywords

CYCLOOXYGENASE 2; FATTY ACID SYNTHASE; GASTRODIN; GLUCOSE; HEME OXYGENASE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; INTERLEUKIN 6; MALONALDEHYDE; MESSENGER RNA; OLEIC ACID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; BENZYL ALCOHOL DERIVATIVE; GLUCOSIDE; PLANT EXTRACT;

ACC1 GENE; ACOX1 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; FAS GENE; GENE; GENE EXPRESSION REGULATION; GLUCOSE HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; LIPID DIET; LIPID HOMEOSTASIS; LIPID METABOLISM; LIPID PEROXIDATION; LIPID STORAGE; LIVER WEIGHT; MALE; METABOLIC REGULATION; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OUTCOME ASSESSMENT; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SREBP1C GENE; UPREGULATION; WEIGHT CHANGE; ANIMAL; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; GASTRODIA; HEP-G2 CELL LINE; HUMAN; INFLAMMATION; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; PATHOLOGY; PHYTOTHERAPY; SPRAGUE DAWLEY RAT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BENZYL ALCOHOLS; GASTRODIA; GLUCOSIDES; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; INFLAMMATION; MALE; MALONDIALDEHYDE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; NON-ALCOHOLIC FATTY LIVER DISEASE; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TRIGLYCERIDES;

EID: 84959432568     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5541     Document Type: Article

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