메뉴 건너뛰기




Volumn 8, Issue 2, 2013, Pages 585-590

LaminaGastrodin ameliorates Parkinson's disease by downregulating connexin 43

Author keywords

Connexin 43; Gap junctional intercellular communication; Gastrodin; Parkinson's disease model; Rotenone

Indexed keywords

CONNEXIN 43; GASTRODIN; ROTENONE; BENZYL ALCOHOL DERIVATIVE; GLUCOSIDE;

EID: 84879934374     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1535     Document Type: Article
Times cited : (47)

References (36)
  • 1
    • 8844266996 scopus 로고    scopus 로고
    • Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
    • Paisán-Ruíz C, Jain S, Evans EW, et al: Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 44: 595-600, 2004.
    • (2004) Neuron , vol.44 , pp. 595-600
    • Paisán-Ruíz, C.1    Jain, S.2    Evans, E.W.3
  • 2
    • 84872287422 scopus 로고    scopus 로고
    • Acetylcholinesterase deficiency decreases apoptosis in dopaminergic neurons in the neurotoxin model of Parkinson's disease
    • Zhang X, Lu L, Liu S, Ye W, Wu J and Zhang X: Acetylcholinesterase deficiency decreases apoptosis in dopaminergic neurons in the neurotoxin model of Parkinson's disease. Int J Biochem Cell Biol 45: 265-272, 2013.
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 265-272
    • Zhang, X.1    Lu, L.2    Liu, S.3    Ye, W.4    Wu, J.5    Zhang, X.6
  • 3
    • 84873034742 scopus 로고    scopus 로고
    • Colchicine protects dopaminergic neurons in a rat model of Parkinson's disease
    • Salama M, Ellaithy A, Helmy B, et al: Colchicine protects dopaminergic neurons in a rat model of Parkinson's disease. CNS Neurol Disord Drug Targets 11: 836-843, 2012.
    • (2012) CNS Neurol Disord Drug Targets , vol.11 , pp. 836-843
    • Salama, M.1    Ellaithy, A.2    Helmy, B.3
  • 4
    • 84873307411 scopus 로고    scopus 로고
    • PEP-1-ribosomal protein S3 protects dopaminergic neurons in an MPTP-induced Parkinson's disease mouse model
    • Ahn EH, Kim DW, Shin MJ, et al: PEP-1-ribosomal protein S3 protects dopaminergic neurons in an MPTP-induced Parkinson's disease mouse model. Free Radic Biol Med 55: 36-45, 2013.
    • (2013) Free Radic Biol Med , vol.55 , pp. 36-45
    • Ahn, E.H.1    Kim, D.W.2    Shin, M.J.3
  • 5
    • 84870198515 scopus 로고    scopus 로고
    • Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease
    • Tönges L, Frank T, Tatenhorst L, et al: Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease. Brain 135: 3355-3370, 2012.
    • (2012) Brain , vol.135 , pp. 3355-3370
    • Tönges, L.1    Frank, T.2    Tatenhorst, L.3
  • 6
    • 84926255701 scopus 로고    scopus 로고
    • Stem cells and the treatment of Parkinson's disease
    • Jan 6, (Epub ahead of print)
    • Ali F, Stott SR and Barker RA: Stem cells and the treatment of Parkinson's disease. Exp Neurol: Jan 6, 2013 (Epub ahead of print).
    • (2013) Exp Neurol
    • Ali, F.1    Stott, S.R.2    Barker, R.A.3
  • 7
    • 84874046508 scopus 로고    scopus 로고
    • Therapeutic application of stem cell technology toward the treatment of Parkinson's disease
    • Nishimura K and Takahashi J: Therapeutic application of stem cell technology toward the treatment of Parkinson's disease. Biol Pharm Bull 36: 171-175, 2013.
    • (2013) Biol Pharm Bull , vol.36 , pp. 171-175
    • Nishimura, K.1    Takahashi, J.2
  • 8
    • 17144372588 scopus 로고    scopus 로고
    • Neuroprotective herbs for stroke therapy in traditional eastern medicine
    • Kim H: Neuroprotective herbs for stroke therapy in traditional eastern medicine. Neurol Res 27: 287-301, 2005.
    • (2005) Neurol Res , vol.27 , pp. 287-301
    • Kim, H.1
  • 9
    • 80655144956 scopus 로고    scopus 로고
    • Herbs in epilepsy: Evidence for efficacy, toxicity, and interactions
    • Pearl PL, Drillings IM and Conry JA: Herbs in epilepsy: evidence for efficacy, toxicity, and interactions. Semin Pediatr Neurol 18: 203-208, 2011.
    • (2011) Semin Pediatr Neurol , vol.18 , pp. 203-208
    • Pearl, P.L.1    Drillings, I.M.2    Conry, J.A.3
  • 10
    • 62949145550 scopus 로고    scopus 로고
    • Botanicals and herbs: A traditional approach to treating epilepsy
    • Schachter SC: Botanicals and herbs: a traditional approach to treating epilepsy. Neurotherapeutics 6: 415-420, 2009.
    • (2009) Neurotherapeutics , vol.6 , pp. 415-420
    • Schachter, S.C.1
  • 11
    • 84862489795 scopus 로고    scopus 로고
    • Gastrodia elata Blume (tianma) mobilizes neuro-protective capacities
    • Manavalan A, Ramachandran U, Sundaramurthi H, et al: Gastrodia elata Blume (tianma) mobilizes neuro-protective capacities. Int J Biochem Mol Biol 3: 219-241, 2012.
    • (2012) Int J Biochem Mol Biol , vol.3 , pp. 219-241
    • Manavalan, A.1    Ramachandran, U.2    Sundaramurthi, H.3
  • 12
    • 84863260868 scopus 로고    scopus 로고
    • Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model rats
    • Li C, Chen X, Zhang N, Song Y and Mu Y: Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model rats. Neural Regen Res 7: 325-331, 2012 (In Chinese).
    • (2012) Neural Regen Res , vol.7 , pp. 325-331
    • Li, C.1    Chen, X.2    Zhang, N.3    Song, Y.4    Mu, Y.5
  • 13
    • 84874547093 scopus 로고    scopus 로고
    • Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats
    • Karuppagounder SS, Madathil KS, Pandey M, Haobam R, Rajamma U and Mohanakumar KP: Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats. Neuroscience 236: 136-148, 2013.
    • (2013) Neuroscience , vol.236 , pp. 136-148
    • Karuppagounder, S.S.1    Madathil, K.S.2    Pandey, M.3    Haobam, R.4    Rajamma, U.5    Mohanakumar, K.P.6
  • 14
    • 84863666597 scopus 로고    scopus 로고
    • Mitochondrial complex i inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson's disease models
    • Xiong N, Long X, Xiong J, et al: Mitochondrial complex I inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson's disease models. Crit Rev Toxicol 42: 613-632, 2012.
    • (2012) Crit Rev Toxicol , vol.42 , pp. 613-632
    • Xiong, N.1    Long, X.2    Xiong, J.3
  • 15
    • 84857782774 scopus 로고    scopus 로고
    • Efficient gene therapy for Parkinson's disease using astrocytes as hosts for localized neurotrophic factor delivery
    • Drinkut A, Tereshchenko Y, Schulz JB, Bähr M and Kügler S: Efficient gene therapy for Parkinson's disease using astrocytes as hosts for localized neurotrophic factor delivery. Mol Ther 20: 534-543, 2012.
    • (2012) Mol Ther , vol.20 , pp. 534-543
    • Drinkut, A.1    Tereshchenko, Y.2    Schulz, J.B.3    Bähr, M.4    Kügler, S.5
  • 16
    • 79953856393 scopus 로고    scopus 로고
    • Astrocytes in Parkinson's disease and DJ-1
    • Hauser DN and Cookson MR: Astrocytes in Parkinson's disease and DJ-1. J Neurochem 117: 357-358, 2011.
    • (2011) J Neurochem , vol.117 , pp. 357-358
    • Hauser, D.N.1    Cookson, M.R.2
  • 17
    • 77957048035 scopus 로고    scopus 로고
    • Astrocytes and therapeutics for Parkinson's disease
    • Rappold PM and Tieu K: Astrocytes and therapeutics for Parkinson's disease. Neurotherapeutics 7: 413-423, 2010.
    • (2010) Neurotherapeutics , vol.7 , pp. 413-423
    • Rappold, P.M.1    Tieu, K.2
  • 18
    • 0035783485 scopus 로고    scopus 로고
    • Connexins and gap junctional communication in astrocytes are targets for neuroglial interaction
    • Rouach N and Giaume C: Connexins and gap junctional communication in astrocytes are targets for neuroglial interaction. Prog Brain Res 132: 203-214, 2001.
    • (2001) Prog Brain Res , vol.132 , pp. 203-214
    • Rouach, N.1    Giaume, C.2
  • 19
    • 0034103898 scopus 로고    scopus 로고
    • Connexin43 null mice reveal that astrocytes express multiple connexins
    • Dermietzel R, Gao Y, Scemes E, et al: Connexin43 null mice reveal that astrocytes express multiple connexins. Brain Res Brain Res Rev 32: 45-56, 2000.
    • (2000) Brain Res Brain Res Rev , vol.32 , pp. 45-56
    • Dermietzel, R.1    Gao, Y.2    Scemes, E.3
  • 20
    • 0034067910 scopus 로고    scopus 로고
    • Connexins and gap junctions of astrocytes and oligodendrocytes in the CNS
    • Nagy JI and Rash JE: Connexins and gap junctions of astrocytes and oligodendrocytes in the CNS. Brain Res Brain Res Rev 32: 29-44, 2000.
    • (2000) Brain Res Brain Res Rev , vol.32 , pp. 29-44
    • Nagy, J.I.1    Rash, J.E.2
  • 21
    • 60849101949 scopus 로고    scopus 로고
    • Connexin and pannexin hemichannels of neurons and astrocytes
    • Thompson RJ and Macvicar BA: Connexin and pannexin hemichannels of neurons and astrocytes. Channels (Austin) 2: 81-86, 2008.
    • (2008) Channels (Austin) , vol.2 , pp. 81-86
    • Thompson, R.J.1    Macvicar, B.A.2
  • 22
    • 0033546257 scopus 로고    scopus 로고
    • Multiple connexins form gap junction channels in rat basilar artery smooth muscle cells
    • Li X and Simard JM: Multiple connexins form gap junction channels in rat basilar artery smooth muscle cells. Circ Res 84: 1277-1284, 1999.
    • (1999) Circ Res , vol.84 , pp. 1277-1284
    • Li, X.1    Simard, J.M.2
  • 23
    • 63649110319 scopus 로고    scopus 로고
    • Modulation of connexin 43 in rotenone-induced model of Parkinson's disease
    • Kawasaki A, Hayashi T, Nakachi K, et al: Modulation of connexin 43 in rotenone-induced model of Parkinson's disease. Neuroscience 160: 61-68, 2009.
    • (2009) Neuroscience , vol.160 , pp. 61-68
    • Kawasaki, A.1    Hayashi, T.2    Nakachi, K.3
  • 24
    • 84894895615 scopus 로고    scopus 로고
    • Effects of gastrodin on Cx43 expression in temporal lobe cortex and hippocampus of pentylenetetrazole-induced epileptic immature rats
    • Ya-qin C, Yi-fan S, Hong C, Jian-ping W and Jiao D: Effects of gastrodin on Cx43 expression in temporal lobe cortex and hippocampus of pentylenetetrazole-induced epileptic immature rats. Journal of Lanzhou University (Medical Sciences) 34: 9, 2008.
    • (2008) Journal of Lanzhou University (Medical Sciences) , vol.34 , pp. 9
    • Ya-Qin, C.1    Yi-Fan, S.2    Hong, C.3    Jian-Ping, W.4    Jiao, D.5
  • 25
    • 84872532026 scopus 로고    scopus 로고
    • The behavioural and neuropathological impact of intranigral AAV-α-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats
    • Mulcahy P, O'Doherty A, Paucard A, O'Brien T, Kirik D and Dowd E: The behavioural and neuropathological impact of intranigral AAV-α-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats. Behav Brain Res 243: 6-15, 2013.
    • (2013) Behav Brain Res , vol.243 , pp. 6-15
    • Mulcahy, P.1    O'Doherty, A.2    Paucard, A.3    O'Brien, T.4    Kirik, D.5    Dowd, E.6
  • 26
    • 84872854169 scopus 로고    scopus 로고
    • Anti-inflammatory properties rather than anti-oxidant capability is the major mechanism of neuroprotection by sodium salicylate in a chronic rotenone model of Parkinson's disease
    • Thakur P and Nehru B: Anti-inflammatory properties rather than anti-oxidant capability is the major mechanism of neuroprotection by sodium salicylate in a chronic rotenone model of Parkinson's disease. Neuroscience 231: 420-431, 2013.
    • (2013) Neuroscience , vol.231 , pp. 420-431
    • Thakur, P.1    Nehru, B.2
  • 27
    • 0003633755 scopus 로고
    • Care IoLARCo, Animals UoL and Resources NIoHDoR, US Department of Health and Human Services, Public Health Service, National Insititutes of Health
    • Care IoLARCo, Animals UoL and Resources NIoHDoR: Guide for the care and use of laboratory animals. US Department of Health and Human Services, Public Health Service, National Insititutes of Health, 1985.
    • (1985) Guide for the Care and Use of Laboratory Animals
  • 28
    • 84857798063 scopus 로고    scopus 로고
    • A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes
    • Wisniewska-Kruk J, Hoeben KA, Vogels IM, et al: A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes. Exp Eye Res 96: 181-190, 2012.
    • (2012) Exp Eye Res , vol.96 , pp. 181-190
    • Wisniewska-Kruk, J.1    Hoeben, K.A.2    Vogels, I.M.3
  • 29
    • 39449123232 scopus 로고    scopus 로고
    • Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP
    • Takizawa T, Gudla PR, Guo L, Lockett S and Misteli T: Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP. Genes Dev 22: 489-498, 2008.
    • (2008) Genes Dev , vol.22 , pp. 489-498
    • Takizawa, T.1    Gudla, P.R.2    Guo, L.3    Lockett, S.4    Misteli, T.5
  • 30
    • 0028248190 scopus 로고
    • The Bradford method for protein quantitation
    • Kruger NJ: The Bradford method for protein quantitation. Methods Mol Biol 32: 9-15, 1994.
    • (1994) Methods Mol Biol , vol.32 , pp. 9-15
    • Kruger, N.J.1
  • 31
    • 84870061246 scopus 로고    scopus 로고
    • Connexin multi-site phosphorylation: Mass spectrometry-based proteomics fills the gap
    • Chen VC, Gouw JW, Naus CC and Foster LJ: Connexin multi-site phosphorylation: mass spectrometry-based proteomics fills the gap. Biochim Biophys Acta 1828: 23-34, 2013.
    • (2013) Biochim Biophys Acta , vol.1828 , pp. 23-34
    • Chen, V.C.1    Gouw, J.W.2    Naus, C.C.3    Foster, L.J.4
  • 32
    • 0025771569 scopus 로고
    • Regulation of connexin 43-mediated gap junctional intercellular communication by Ca2+ in mouse epidermal cells is controlled by E-cadherin
    • Jongen WM, Fitzgerald DJ, Asamoto M, et al: Regulation of connexin 43-mediated gap junctional intercellular communication by Ca2+ in mouse epidermal cells is controlled by E-cadherin. J Cell Biol 114: 545-555, 1991.
    • (1991) J Cell Biol , vol.114 , pp. 545-555
    • Jongen, W.M.1    Fitzgerald, D.J.2    Asamoto, M.3
  • 33
    • 84873315417 scopus 로고    scopus 로고
    • Differential association of postsynaptic signaling protein complexes in striatum and hippocampus
    • Baucum AJ II, Brown AM and Colbran RJ: Differential association of postsynaptic signaling protein complexes in striatum and hippocampus. J Neurochem 124: 490-501, 2013.
    • (2013) J Neurochem , vol.124 , pp. 490-501
    • Baucum, A.J.I.I.1    Brown, A.M.2    Colbran, R.J.3
  • 34
    • 84855880846 scopus 로고    scopus 로고
    • Functional interaction between the dorsal hippocampus and the striatum in visual discrimination learning
    • Fidalgo C, Conejo NM, González-Pardo H and Arias JL: Functional interaction between the dorsal hippocampus and the striatum in visual discrimination learning. J Neurosci Res 90: 715-720, 2012.
    • (2012) J Neurosci Res , vol.90 , pp. 715-720
    • Fidalgo, C.1    Conejo, N.M.2    González-Pardo, H.3    Arias, J.L.4
  • 35
    • 34447531020 scopus 로고    scopus 로고
    • Protective effects of gastrodin on hypoxia-induced toxicity in primary cultures of rat cortical neurons
    • Xu X, Lu Y and Bie X: Protective effects of gastrodin on hypoxia-induced toxicity in primary cultures of rat cortical neurons. Planta Med 73: 650-654, 2007.
    • (2007) Planta Med , vol.73 , pp. 650-654
    • Xu, X.1    Lu, Y.2    Bie, X.3
  • 36
    • 84872787640 scopus 로고    scopus 로고
    • The interfaces between signal transduction pathways: IGF-1/mTor, p53 and the Parkinson Disease pathway
    • Levine AJ, Harris CR and Puzio-Kuter AM: The interfaces between signal transduction pathways: IGF-1/mTor, p53 and the Parkinson Disease pathway. Oncotarget 3: 1301-1307, 2012.
    • (2012) Oncotarget , vol.3 , pp. 1301-1307
    • Levine, A.J.1    Harris, C.R.2    Puzio-Kuter, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.