-
1
-
-
21344449292
-
Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study
-
Bedogni G, Miglioli L, Masutti F, Tiribelli C, Marchesini G and Bellentani S, Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study. Hepatology 42:44-52 (2005).
-
(2005)
Hepatology
, vol.42
, pp. 44-52
-
-
Bedogni, G.1
Miglioli, L.2
Masutti, F.3
Tiribelli, C.4
Marchesini, G.5
Bellentani, S.6
-
2
-
-
33644547706
-
Nonalcoholic fatty liver disease: From steatosis to cirrhosis
-
Farrell GC and Larter CZ, Nonalcoholic fatty liver disease: From steatosis to cirrhosis. Hepatology 43:S99-S112 (2006).
-
(2006)
Hepatology
, vol.43
-
-
Farrell, G.C.1
Larter, C.Z.2
-
3
-
-
77951456114
-
Nonalcoholic fatty liver disease and hepatocellular carcinoma a weighty connection
-
Starley BQ, Calcagno CJ and Harrison SA, Nonalcoholic fatty liver disease and hepatocellular carcinoma a weighty connection. Hepatology 51:1820-1832 (2010).
-
(2010)
Hepatology
, vol.51
, pp. 1820-1832
-
-
Starley, B.Q.1
Calcagno, C.J.2
Harrison, S.A.3
-
5
-
-
77951874018
-
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis
-
Sanyal AJ, Chalasani N, Kowdley KV, McCullough A, Diehl AM, Bass NM, et al., Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med 362:1675-1685 (2010).
-
(2010)
N Engl J Med
, vol.362
, pp. 1675-1685
-
-
Sanyal, A.J.1
Chalasani, N.2
Kowdley, K.V.3
McCullough, A.4
Diehl, A.M.5
Bass, N.M.6
-
6
-
-
0012785395
-
Metformin reverses fatty liver disease in obese, leptin-deficient mice
-
Lin HZ, Yang SQ, Chuckaree C, Kuhajda F, Ronnet G and Diehl AM, Metformin reverses fatty liver disease in obese, leptin-deficient mice. Nat Med 6:998-1003 (2000).
-
(2000)
Nat Med
, vol.6
, pp. 998-1003
-
-
Lin, H.Z.1
Yang, S.Q.2
Chuckaree, C.3
Kuhajda, F.4
Ronnet, G.5
Diehl, A.M.6
-
7
-
-
0035029874
-
Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats
-
Bergeron R, Previs SF, Cline GW, Perret P, Russell 3rd RR, Young LH, et al., Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes 50:1076-1082 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 1076-1082
-
-
Bergeron, R.1
Previs, S.F.2
Cline, G.W.3
Perret, P.4
Russell, III.R.R.5
Young, L.H.6
-
8
-
-
75349099919
-
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
-
Fogarty S and Hardie DG, Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer. Biochim Biophys Acta 1804:581-591 (2010).
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 581-591
-
-
Fogarty, S.1
Hardie, D.G.2
-
9
-
-
0033559856
-
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target
-
Muoio DM, Seefeld K, Witters LA and Coleman RA, AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. Biochem J 338:783-791 (1999).
-
(1999)
Biochem J
, vol.338
, pp. 783-791
-
-
Muoio, D.M.1
Seefeld, K.2
Witters, L.A.3
Coleman, R.A.4
-
10
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD and Parks EJ, Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115:1343-1351 (2005).
-
(2005)
J Clin Invest
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
11
-
-
18844458833
-
Dietary fat content modifies liver fat in overweight nondiabetic subjects
-
Westerbacka J, Lammi K, Hakkinen AM, Rissanen A, Salminen I, Aro A, et al., Dietary fat content modifies liver fat in overweight nondiabetic subjects. J Clin Endocrinol Metab 90:2804-2809 (2005).
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 2804-2809
-
-
Westerbacka, J.1
Lammi, K.2
Hakkinen, A.M.3
Rissanen, A.4
Salminen, I.5
Aro, A.6
-
12
-
-
2942706241
-
Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease
-
Aray J, Rodrigo R, Videla LA, Thielemann L, Orellana M, Pettinelli P, et al., Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease. Clin Sci (Lond) 106:635-643 (2004).
-
(2004)
Clin Sci (Lond)
, vol.106
, Issue.635-643
-
-
Aray, J.1
Rodrigo, R.2
Videla, L.A.3
Thielemann, L.4
Orellana, M.5
Pettinelli, P.6
-
13
-
-
79957561550
-
Lipotoxicity in HepG2 cells triggered by free fatty acids
-
Yao HR, Liu J, Plumeri D, Cao YB, He T, Lin L, et al., Lipotoxicity in HepG2 cells triggered by free fatty acids. Am J Transl Res 3:284-291 (2011).
-
(2011)
Am J Transl Res
, vol.3
, pp. 284-291
-
-
Yao, H.R.1
Liu, J.2
Plumeri, D.3
Cao, Y.B.4
He, T.5
Lin, L.6
-
14
-
-
33748794808
-
A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury
-
Svegliati-Baroni G, Candelaresi C, Saccomanno S, Ferretti G, Bachetti T, Marzioni M, et al., A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury. Am J Pathol 169:846-860 (2006).
-
(2006)
Am J Pathol
, vol.169
, pp. 846-860
-
-
Svegliati-Baroni, G.1
Candelaresi, C.2
Saccomanno, S.3
Ferretti, G.4
Bachetti, T.5
Marzioni, M.6
-
15
-
-
0034666132
-
Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting
-
Hashimoto T, Cook WS, Qi C, Yeldandi AV, Reddy JK and Rao MS, Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting. J Biol Chem 275:28918-28928 (2000).
-
(2000)
J Biol Chem
, vol.275
, pp. 28918-28928
-
-
Hashimoto, T.1
Cook, W.S.2
Qi, C.3
Yeldandi, A.V.4
Reddy, J.K.5
Rao, M.S.6
-
16
-
-
0029888128
-
Structure-antioxidant activity relationships of flavonoids and phenolic acids
-
Rice-Evans CA, Miller NJ and Paganga G, Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med 20:933-956 (1996).
-
(1996)
Free Radic Biol Med
, vol.20
, pp. 933-956
-
-
Rice-Evans, C.A.1
Miller, N.J.2
Paganga, G.3
-
17
-
-
11844260060
-
Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza
-
Jiang RW, Lau KM, Hon PM, Mak TC, Woo KS and Fung KP, Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza. Curr Med Chem 12:237-246 (2005).
-
(2005)
Curr Med Chem
, vol.12
, pp. 237-246
-
-
Jiang, R.W.1
Lau, K.M.2
Hon, P.M.3
Mak, T.C.4
Woo, K.S.5
Fung, K.P.6
-
18
-
-
33746869949
-
Impact of alkyl esters of caffeic and ferulic acids on tumor cell proliferation, cyclooxygenase enzyme, and lipid peroxidation
-
Jayaprakasam B, Vanisree M, Zhang Y, Dewitt DL and Nair MG, Impact of alkyl esters of caffeic and ferulic acids on tumor cell proliferation, cyclooxygenase enzyme, and lipid peroxidation. J Agric Food Chem 54:5375-5381 (2006).
-
(2006)
J Agric Food Chem
, vol.54
, pp. 5375-5381
-
-
Jayaprakasam, B.1
Vanisree, M.2
Zhang, Y.3
Dewitt, D.L.4
Nair, M.G.5
-
20
-
-
0346336175
-
Inhibitory effect of caffeic acid phenethyl ester on angiogenesis, tumor invasion, and metastasis
-
Liao HF, Chen YY, Liu JJ, Hsu ML, Shieh HJ, Liao HJ, et al., Inhibitory effect of caffeic acid phenethyl ester on angiogenesis, tumor invasion, and metastasis. J Agric Food Chem 51:7907-7912 (2003).
-
(2003)
J Agric Food Chem
, vol.51
, pp. 7907-7912
-
-
Liao, H.F.1
Chen, Y.Y.2
Liu, J.J.3
Hsu, M.L.4
Shieh, H.J.5
Liao, H.J.6
-
21
-
-
33745948316
-
Antihyperglycemic and antioxidant properties of caffeic acid in db/db mice
-
Jung UJ, Lee MK, Park YB, Jeon SM and Choi MS, Antihyperglycemic and antioxidant properties of caffeic acid in db/db mice. J Pharmacol Exp Ther 318:476-483 (2006).
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 476-483
-
-
Jung, U.J.1
Lee, M.K.2
Park, Y.B.3
Jeon, S.M.4
Choi, M.S.5
-
22
-
-
52449095532
-
Caffeic acid alleviates the increased lipid levels of serum and tissues in alcohol-induced [hepatotoxicity in] rats
-
Karthikesan K and Pari L, Caffeic acid alleviates the increased lipid levels of serum and tissues in alcohol-induced [hepatotoxicity in] rats. Fundam Clin Pharmacol 22:523-527 (2008).
-
(2008)
Fundam Clin Pharmacol
, vol.22
, pp. 523-527
-
-
Karthikesan, K.1
Pari, L.2
-
23
-
-
77950809499
-
Protective effects of caffeic acid phenethyl ester on iron-induced liver damage in rats
-
Oktar S, Yonden Z, Aydin M, Ilhan S, Alcin E and Ozturk OH, Protective effects of caffeic acid phenethyl ester on iron-induced liver damage in rats. J Physiol Biochem 65:339-344 (2009).
-
(2009)
J Physiol Biochem
, vol.65
, pp. 339-344
-
-
Oktar, S.1
Yonden, Z.2
Aydin, M.3
Ilhan, S.4
Alcin, E.5
Ozturk, O.H.6
-
24
-
-
77949487413
-
The effect of caffeic acid phenethyl ester (CAPE) against cholestatic liver injury in rats
-
Coban S, Yildiz F, Terzi A, Al B, Ozgor D, Ara C, et al., The effect of caffeic acid phenethyl ester (CAPE) against cholestatic liver injury in rats. J Surg Res 159:674-679 (2010).
-
(2010)
J Surg Res
, vol.159
, pp. 674-679
-
-
Coban, S.1
Yildiz, F.2
Terzi, A.3
Al, B.4
Ozgor, D.5
Ara, C.6
-
25
-
-
3242748962
-
Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents
-
Janbaz KH, Saeed SA and Gilani AH, Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents. Phytomedicine 11:424-430 (2004).
-
(2004)
Phytomedicine
, vol.11
, pp. 424-430
-
-
Janbaz, K.H.1
Saeed, S.A.2
Gilani, A.H.3
-
26
-
-
0035111325
-
Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1
-
Cousin SP, Hugl SR, Wrede CE, Kajio H, Myers Jr MG and Rhodes CJ, Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1. Endocrinology 142:229-240 (2001).
-
(2001)
Endocrinology
, vol.142
, pp. 229-240
-
-
Cousin, S.P.1
Hugl, S.R.2
Wrede, C.E.3
Kajio, H.4
Myers Jr, M.G.5
Rhodes, C.J.6
-
27
-
-
0021923858
-
Nile red: A selective fluorescent stain for intracellular lipid droplets
-
Greenspan P, Mayer EP and Fowler SD, Nile red: A selective fluorescent stain for intracellular lipid droplets. J Cell Biol 100:965-973 (1985).
-
(1985)
J Cell Biol
, vol.100
, pp. 965-973
-
-
Greenspan, P.1
Mayer, E.P.2
Fowler, S.D.3
-
28
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
Bligh EG and Dyer WJ, A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911-917 (1959).
-
(1959)
Can J Biochem Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
30
-
-
77950323927
-
Pathogenesis of non-alcoholic fatty liver disease
-
Dowman JK, Tomlinson JW and Newsome PN, Pathogenesis of non-alcoholic fatty liver disease. Q J Med 103:71-83 (2010).
-
(2010)
Q J Med
, vol.103
, pp. 71-83
-
-
Dowman, J.K.1
Tomlinson, J.W.2
Newsome, P.N.3
-
31
-
-
0036251153
-
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton JD, Goldstein JL and Brown MS, SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109:1125-1131 (2002).
-
(2002)
J Clin Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
32
-
-
79955399980
-
A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells
-
Lian Z, Li Y, Gao J, Qu K, Li J, Hao L, et al., A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells. Lipids Health Dis 10:67 (2011).
-
(2011)
Lipids Health Dis
, vol.10
, pp. 67
-
-
Lian, Z.1
Li, Y.2
Gao, J.3
Qu, K.4
Li, J.5
Hao, L.6
-
33
-
-
27144483324
-
AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats
-
Assifi MM, Suchankova G, Constant S, Prentki M, Saha AK and Ruderman NB, AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats. Am J Physiol Endocrinol Metab 289:E794-E800 (2005).
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
-
-
Assifi, M.M.1
Suchankova, G.2
Constant, S.3
Prentki, M.4
Saha, A.K.5
Ruderman, N.B.6
-
34
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, et al., Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108:1167-1174 (2001).
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
-
35
-
-
78349283454
-
Peroxisome proliferator- activated receptor alpha target genes
-
Rakhshandehroo M, Knoch B, Muller M and Kersten S, Peroxisome proliferator- activated receptor alpha target genes. PPAR Res 2010:612089 (2010).
-
(2010)
PPAR Res
, vol.2010
, pp. 612089
-
-
Rakhshandehroo, M.1
Knoch, B.2
Muller, M.3
Kersten, S.4
-
36
-
-
77957654223
-
Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice
-
Lee MS, Kim D, Jo K and Hwang JK, Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice. Biochem Biophys Res Commun 401:92-97 (2010).
-
(2010)
Biochem Biophys Res Commun
, vol.401
, pp. 92-97
-
-
Lee, M.S.1
Kim, D.2
Jo, K.3
Hwang, J.K.4
-
37
-
-
84877890083
-
Amelioration by chicory seed extract of diabetes- and oleic acid-induced non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) via modulation of PPARalpha and SREBP-1
-
Ziamajidi N, Khaghani S, Hassanzadeh G, Vardasbi S, Ahmadian S, Nowrouzi A, et al., Amelioration by chicory seed extract of diabetes- and oleic acid-induced non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) via modulation of PPARalpha and SREBP-1. Food Chem Toxicol 58:198-209 (2013).
-
(2013)
Food Chem Toxicol
, vol.58
, pp. 198-209
-
-
Ziamajidi, N.1
Khaghani, S.2
Hassanzadeh, G.3
Vardasbi, S.4
Ahmadian, S.5
Nowrouzi, A.6
-
38
-
-
79952703368
-
PPAR/RXR regulation of fatty acid metabolism and fatty acid omega-hydroxylase (CYP4) isozymes: Implications for prevention of lipotoxicity in fatty liver disease
-
Hardwick JP, Osei-Hyiaman D, Wiland H, Abdelmegeed MA and Song BJ, PPAR/RXR regulation of fatty acid metabolism and fatty acid omega-hydroxylase (CYP4) isozymes: Implications for prevention of lipotoxicity in fatty liver disease. PPAR Res 2009:952734 (2009).
-
(2009)
PPAR Res
, vol.2009
, pp. 952734
-
-
Hardwick, J.P.1
Osei-Hyiaman, D.2
Wiland, H.3
Abdelmegeed, M.A.4
Song, B.J.5
-
39
-
-
0037115762
-
Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport
-
Field FJ, Born E, Murthy S and Mathur SN, Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport. Biochem J 368:855-864 (2002).
-
(2002)
Biochem J
, vol.368
, pp. 855-864
-
-
Field, F.J.1
Born, E.2
Murthy, S.3
Mathur, S.N.4
-
41
-
-
77954385136
-
Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements
-
Song S, Attia RR, Connaughton S, Niesen MI, Ness GC, Elam MB, et al., Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements. Mol Cell Endocrinol 325:54-63 (2010).
-
(2010)
Mol Cell Endocrinol
, vol.325
, pp. 54-63
-
-
Song, S.1
Attia, R.R.2
Connaughton, S.3
Niesen, M.I.4
Ness, G.C.5
Elam, M.B.6
-
42
-
-
67349154078
-
Liver type fatty acid binding protein (L-FABP) gene ablation reduces nuclear ligand distribution and peroxisome proliferator-activated receptor-alpha activity in cultured primary hepatocytes
-
McIntosh AL, Atshaves BP, Hostetler HA, Huang H, Davi J, Lyuksyutova OI, et al., Liver type fatty acid binding protein (L-FABP) gene ablation reduces nuclear ligand distribution and peroxisome proliferator-activated receptor-alpha activity in cultured primary hepatocytes. Arch Biochem Biophys 485:160-173 (2009).
-
(2009)
Arch Biochem Biophys
, vol.485
, pp. 160-173
-
-
McIntosh, A.L.1
Atshaves, B.P.2
Hostetler, H.A.3
Huang, H.4
Davi, J.5
Lyuksyutova, O.I.6
-
43
-
-
1942442399
-
Liver fatty acid binding protein expression enhances branched-chain fatty acid metabolism
-
Atshaves BP, Storey SM, Huang H and Schroeder F, Liver fatty acid binding protein expression enhances branched-chain fatty acid metabolism. Mol Cell Biochem 259:115-129 (2004).
-
(2004)
Mol Cell Biochem
, vol.259
, pp. 115-129
-
-
Atshaves, B.P.1
Storey, S.M.2
Huang, H.3
Schroeder, F.4
|