Gastrodin attenuation of the inflammatory response in H9c2 cardiomyocytes involves inhibition of NF-κB and MAPKs activation via the phosphatidylinositol 3-kinase signaling

Biochemical Pharmacology

Volumn 85, Issue 8, 2013, Pages 1124-1133

  Yang, Ping ^a   Han, Yi ^a   Gui, Li ^b   Sun, Jun ^a   Chen, Yuan Li ^a   Song, Rui ^a   Guo, Jia Zhi ^a   Xie, Ya Nan ^a   Lu, Di ^a   Sun, Lin ^a  

^a KUNMING MEDICAL UNIVERSITY   (China)

^b The Third People's Hospital of Yunnan Province   (China)

Author keywords

Gastrodin; H9c2 cardiomyocytes; Inflammatory response; NF B; PI3 K Akt

Indexed keywords

CYCLOOXYGENASE 2; GASTRODIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; JANUS KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL VIABILITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART MUSCLE CELL; IMMUNE RESPONSE; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; UPREGULATION;

ANDROSTADIENES; ANIMALS; ANTI-INFLAMMATORY AGENTS; BENZYL ALCOHOLS; CELL SURVIVAL; CELLS, CULTURED; ENZYME ACTIVATION; GLUCOSIDES; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, CARDIAC; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RATS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84875229989     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.01.020     Document Type: Article

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