Biochemical characterization of two functional human liver acyl-CoA oxidase isoforms 1a and 1b encoded by a single gene

Biochemical and Biophysical Research Communications

Volumn 360, Issue 2, 2007, Pages 314-319

  Oaxaca Castillo, David ^a,b,c   Andreoletti, Pierre ^a,b,c   Vluggens, Aurore ^a,b,c   Yu, Sangtao ^d   van Veldhoven, Paul P ^e   Reddy, Janardan K ^d   Cherkaoui Malki, Mustapha ^a,b,c  

^a Chu   (France)

^b UNIVERSITÉ DE BOURGOGNE   (France)

^c GDR CNRS 2583   (France)

^d NORTHWESTERN UNIVERSITY   (United States)

^e Faculteit Geneeskunde   (Belgium)

Author keywords

Oxidation; Acyl CoA oxidase; Fatty acids; Isoform; Peroxisomes

Indexed keywords

ACYL COENZYME A OXIDASE; RNA;

ANIMAL CELL; ARTICLE; CATALYSIS; CHEMICAL ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA SPLICING; TISSUE DIFFERENTIATION;

ACYL-COA OXIDASE; ENZYME ACTIVATION; ENZYME STABILITY; HUMANS; ISOENZYMES; LIVER; MOLECULAR WEIGHT;

ESCHERICHIA COLI;

EID: 34447108840     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.06.059     Document Type: Article

References (20)

1. Wanders R.J. Peroxisomes, lipid metabolism, and peroxisomal disorders. Mol. Genet. Metab. 83 (2004) 16-27
2. Funato M., Shimozawa N., Nagase T., Takemoto Y., Suzuki Y., Imamura Y., Matsumoto T., Tsukamoto T., Kojidani T., Osumi T., Fukao T., and Kondo N. Aberrant peroxisome morphology in peroxisomal β-oxidation enzyme deficiencies. Brain Dev. 28 (2006) 287-292
3. Rosewich H., Waterham H.R., Wanders R.J., Ferdinandusse S., Henneke M., Hunneman D., and Gartner J. Pitfall in metabolic screening in a patient with fatal peroxisomal β-oxidation defect. Neuropediatrics 37 (2006) 95-98
4. Fan C.Y., Pan J., Chu R., Lee D., Kluckman K.D., Usuda N., Singh I., Yeldandi A.V., Rao M.S., Maeda N., and Reddy J.K. Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene. J. Biol. Chem. 271 (1996) 24698-24710
5. Varanasi U., Chu R., Chu S., Espinosa R., LeBeau M.M., and Reddy J.K. Isolation of the human peroxisomal acyl-CoA oxidase gene: organization, promoter analysis, and chromosomal localization. Proc. Natl. Acad. Sci. USA 91 (1994) 3107-3111
6. Chu R., Varanasi U., Chu S., Lin Y., Usuda N., Rao M.S., and Reddy J.K. Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells. J. Biol. Chem. 270 (1995) 4908-4915
7. Subramani S., Koller A., and Snyder W.B. Import of peroxisomal matrix and membrane proteins. Annu. Rev. Biochem. 69 (2000) 399-418
8. Morais S., Knoll-Gellida A., Andre M., Barthe C., and Babin P.J. Conserved expression of alternative splicing variants of peroxisomal acyl-CoA oxidase 1 in vertebrates and developmental and nutritional regulation in fish. Physiol. Genomics 28 (2007) 239-252
9. Osumi T., Ishii N., Miyazawa S., and Hashimoto T. Isolation and structural characterization of the rat acyl-CoA oxidase gene. J. Biol. Chem. 262 (1987) 8138-8143
10. Van Veldhoven P.P., Vanhove G., Assselberghs S., Eyssen H.J., and Mannaerts G.P. Substrate specificities of rat liver peroxisomal acyl-CoA oxidases: palmitoyl-CoA oxidase (inducible acyl-CoA oxidase), pristanoyl-CoA oxidase (non-inducible acyl-CoA oxidase), and trihydroxycoprostanoyl-CoA oxidase. J. Biol. Chem. 267 (1992) 20065-20074
11. Brown L.A., and Baker A. Peroxisome biogenesis and the role of protein import. J. Cell Mol. Med. 7 (2003) 388-400
12. Osumi T., Hashimoto T., and Ui N. Purification and properties of acyl-CoA oxidase from rat liver. J. Biochem. (Tokyo) 87 (1980) 1735-1746
13. Vamecq J. Fluorometric assay of peroxisomal oxidases. Anal. Biochem. 186 (1990) 340-349
14. Brocard C., Es-Souni M., Ramirez L.C., Latruffe N., and Bournot P. Stimulation of peroxisomal palmitoyl-CoA oxidase activity by ciprofibrate in hepatic cell lines: comparative studies in Fao, MH1C1 and HepG2 cells. Biol. Cell 77 (1993) 37-41
15. Inestrosa N.C., Bronfman M., and Leighton F. Purification of the peroxisomal fatty acyl-CoA oxidase from rat liver. Biochem. Biophys. Res. Commun. 95 (1980) 7-12
16. Casteels M., Schepers L., Van Veldhoven P.P., Eyssen H.J., and Mannaerts G.P. Separate peroxisomal oxidases for fatty acyl-CoAs and trihydroxycoprostanoyl-CoA in human liver. J. Lipid Res. 31 (1990) 1865-1872
17. Chu R., Usuda N., Reddy M.K., Liu C., Hashimoto T., Alvares K., Rao M.S., and Reddy J.K. Functional expression of rat peroxisomal acyl-CoA oxidase in Spodoptera frugiperda cells. Biochem. Biophys. Res. Commun. 200 (1994) 178-186
18. Setoyama C., Tamaoki H., Nishina Y., Shiga K., and Miura R. Functional expression of two forms of rat acyl-CoA oxidase and their substrate specificities. Biochem. Biophys. Res. Commun. 217 (1995) 482-487
19. Wanders R.J., and Waterham H.R. Biochemistry of mammalian peroxisomes revisited. Annu. Rev. Biochem. 75 (2006) 295-332
20. Ferdinandusse S., Denis S., Mooijer P.A., Zhang Z., Reddy J.K., Spector A.A., and Wanders R.J. Identification of the peroxisomal β-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid. J. Lipid Res. 42 (2001) 1987-1995