A purified Feverfew extract protects from oxidative damage by inducing DNA repair in skin cells via a PI3-kinase-dependent Nrf2/ARE pathway

Journal of Dermatological Science

Volumn 72, Issue 3, 2013, Pages 304-310

  Rodriguez, Karien J ^a   Wong, Heng Kuan ^b   Oddos, Thierry ^b   Southall, Michael ^a   Frei, Balz ^c   Kaur, Simarna ^a  

^a JOHNSON AND JOHNSON   (United States)

^b Pharmacology Department   (France)

^c OREGON STATE UNIVERSITY   (United States)

Author keywords

Antioxidants; ARE; DNA repair; Feverfew; Nrf2

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; DNA; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; TANACETUM PARTHENIUM EXTRACT; TRANSCRIPTION FACTOR NRF2;

ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA REPAIR; DRUG SCREENING; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTRACELLULAR SIGNALING; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SKIN CELL; SKIN PROTECTION; ULTRAVIOLET RADIATION; WESTERN BLOTTING;

ANTIOXIDANTS; ARE; DNA REPAIR; FEVERFEW; NRF2;

ANTIOXIDANT RESPONSE ELEMENTS; DNA REPAIR; DRUG EVALUATION, PRECLINICAL; HUMANS; KB CELLS; KERATINOCYTES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; TANACETUM PARTHENIUM;

EID: 84887188860     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2013.08.004     Document Type: Article

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