System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes

Molecular Cell

Volumn 62, Issue 1, 2016, Pages 121-136

  Zhang, Wei ^a   Wu, Kuen Phon ^b   Sartori, Maria A ^a   Kamadurai, Hari B ^b,j   Ordureau, Alban ^c   Jiang, Chong ^d   Mercredi, Peter Y ^b   Murchie, Ryan ^d   Hu, Jicheng ^e   Persaud, Avinash ^d   Mukherjee, Manjeet ^b,k   Li, Nan ^f   Doye, Anne ^g   Walker, John R ^e   Sheng, Yi ^h   Hao, Zhenyue ⁱ   Li, Yanjun ^e   Brown, Kevin R ^a   Lemichez, Emmanuel ^g   Chen, Junjie ^f   Tong, Yufeng ^e   Harper, J Wade ^c   Moffat, Jason ^a   Rotin, Daniela ^d   Schulman, Brenda A ^b   Sidhu, Sachdev S ^a   more..

^a UNIVERSITY OF TORONTO   (Canada)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^g CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^h YORK UNIVERSITY   (Canada)

ⁱ UNIVERSITY HEALTH NETWORK   (Canada)

^j BIOGEN   (United States)

^k UNIVERSITY OF LEICESTER   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; HOMOLOGOUS TO E6AP C TERMINUS E3 LIGASE; LENTIVIRUS VECTOR; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E2; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE HACE1; UBIQUITIN PROTEIN LIGASE HUWE1; UBIQUITIN PROTEIN LIGASE ITCH; UBIQUITIN PROTEIN LIGASE NEDD4; UBIQUITIN PROTEIN LIGASE NEDD4L; UBIQUITIN PROTEIN LIGASE RSP5; UBIQUITIN PROTEIN LIGASE WWP1; UBIQUITIN PROTEIN LIGASE WWP2; UNCLASSIFIED DRUG; PEPTIDE LIBRARY;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL MIGRATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENETIC SCREENING; HCT116 CELL LINE; HUMAN; HUMAN CELL; INTESTINE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UBIQUITINATION; ANIMAL; CELL LINE; CELL MOTION; CHEMISTRY; CYTOLOGY; CYTOPLASM; DOG; ENZYME ACTIVE SITE; GENETICS; HCT 116 CELL LINE; MDCK CELL LINE; METABOLISM; MOLECULAR MODEL; PEPTIDE LIBRARY;

ANIMALS; CATALYTIC DOMAIN; CELL LINE; CELL MOVEMENT; DOGS; HCT116 CELLS; HUMANS; MADIN DARBY CANINE KIDNEY CELLS; MODELS, MOLECULAR; ORGANOIDS; PEPTIDE LIBRARY; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84959285658     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.02.005     Document Type: Article

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