Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

EMBO Reports

Volumn 12, Issue 4, 2011, Pages 342-349

  Maspero, Elena ^a   Mari, Sara ^a   Valentini, Eleonora ^a   Musacchio, Andrea ^b   Fish, Alexander ^c   Pasqualato, Sebastiano ^b,d   Polo, Simona ^a,e  

^a IFOM   (Italy)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d IFOM IEO Campus   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

catalysis; E3 ligase; polyubiquitination; structure; ubiquitin

Indexed keywords

CYSTEINE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE HECT; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; MUTATIONAL ANALYSIS; POLYUBIQUITINATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SELF UBIQUITINATION; UBIQUITINATION;

AMINO ACID SEQUENCE; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; X-RAY DIFFRACTION;

EID: 79953325889     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2011.21     Document Type: Article

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