A strategy for modulation of enzymes in the ubiquitin system

Science

Volumn 339, Issue 6119, 2013, Pages 590-595

  Ernst, Andreas ^a   Avvakumov, George ^b   Tong, Jiefei ^c   Fan, Yihui ^d   Zhao, Yanling ^d   Alberts, Philipp ^c   Persaud, Avinash ^c,e   Walker, John R ^b   Neculai, Ana Mirela ^a   Neculai, Dante ^a   Vorobyov, Andrew ^a   Garg, Pankaj ^a   Beatty, Linda ^a   Chan, Pak Kei ^f   Juang, Yu Chi ^g   Landry, Marie Claude ^g   Yeh, Christina ^a,g   Zeqiraj, Elton ^g   Karamboulas, Konstantina ^a   Allali Hassani, Abdellah ^b   Vedadi, Masoud ^b   Tyers, Mike ^f,g   Moffat, Jason ^a,e,h   Sicheri, Frank ^a,g   Pelletier, Laurence ^a,g   Durocher, Daniel ^a,g   Raught, Brian ^h   Rotin, Daniela ^c,e   Yang, Jianhua ^d   Moran, Michael F ^a,c,e   Dhe Paganon, Sirano ^a,b   Sidhu, Sachdev S ^a,e,h   more..

^a UNIVERSITY OF TORONTO   (Canada)

^b Structural Genomics Consortium   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^g MOUNT SINAI HOSPITAL   (Canada)

^h PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE;

BIOCHEMISTRY; CHEMICAL BINDING; ENZYME ACTIVITY; INHIBITOR; PROTEIN;

ARTICLE; COMBINATORIAL LIBRARY; COMPLEX FORMATION; CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYME ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; UBIQUITINATION;

EID: 84873085753     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1230161     Document Type: Article

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