-
1
-
-
84875849476
-
Detection of nanolevel drug metabolites in an organotypic culture ofprimary human hepatocytes and porcine hepatocytes with special reference to a two-compartment model
-
Acikgoz A, Giri S, Bader A. Detection of nanolevel drug metabolites in an organotypic culture ofprimary human hepatocytes and porcine hepatocytes with special reference to a two-compartment model. Int J Nanomed 2012; 7:5859–5872.
-
(2012)
Int J Nanomed
, vol.7
, pp. 5859-5872
-
-
Acikgoz, A1
Giri, S2
Bader, A.3
-
2
-
-
84894371076
-
The frequency of drug-induced liver injury (DILI) among patients receiving potentially hepatotoxic drugs: a population based study
-
Bjornsson E, Bergmann O, Bjornsson HK, Olafsson S. The frequency of drug-induced liver injury (DILI) among patients receiving potentially hepatotoxic drugs: a population based study. Hepatology 2012;56:594a– 595a. doi: 10.1002/hep.25702.
-
(2012)
Hepatology
, vol.56
, pp. 594a-595a
-
-
Bjornsson, E1
Bergmann, O2
Bjornsson, HK3
Olafsson, S.4
-
3
-
-
77953741231
-
The Characteristics and Clinical Outcome of Drug-induced Liver Injury A Singlecenter Experience
-
Idilman R, Bektas M, Cinar K, Toruner M, Cerit ET, Doganay B, et al. The Characteristics and Clinical Outcome of Drug-induced Liver Injury A Singlecenter Experience. J Clin Gastroenterol 2010;44:E128–E132. doi: 10.1097/MCG.0b013e3181c5e9cc.
-
(2010)
J Clin Gastroenterol
, vol.44
, pp. E128-E132
-
-
Idilman, R1
Bektas, M2
Cinar, K3
Toruner, M4
Cerit, ET5
Doganay, B6
-
5
-
-
79956321804
-
Drug safety sciences and the bottleneck in drug development
-
Watkins PB. Drug safety sciences and the bottleneck in drug development. Clin Pharmacol Ther 2011;89:788–790. doi: 10.1038/clpt.2011.63.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 788-790
-
-
Watkins, PB.1
-
6
-
-
80051665573
-
FDA-approved drug labeling for the study of drug-induced liver injury
-
Chen MJ, Vijay V, Shi Q, Liu ZC, Fang H, Tong WD. FDA-approved drug labeling for the study of drug-induced liver injury. Drug Discov Today 2011; 16:697–703. doi: 10.1016/j.drudis.2011.05.007.
-
(2011)
Drug Discov Today
, vol.16
, pp. 697-703
-
-
Chen, MJ1
Vijay, V2
Shi, Q3
Liu, ZC4
Fang, H5
Tong, WD.6
-
7
-
-
78649625452
-
Drug-Induced Acute Liver Failure: Results of a U.S. Multicenter, Prospective Study
-
Reuben A, Koch DG, Lee WM, Grp ALFS. Drug-Induced Acute Liver Failure: Results of a U.S. Multicenter, Prospective Study. Hepatology 2010;52: 2065–2076. doi: 10.1002/hep.23937.
-
(2010)
Hepatology
, vol.52
, pp. 2065-2076
-
-
Reuben, A1
Koch, DG2
Lee, WM3
Grp, ALFS.4
-
9
-
-
57249086242
-
Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-induced Liver Injury in the United States
-
Chalasani N, Fontana RJ, Bonkovsky HL, Watkins PB, Davern T, Serrano J, et al. Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-induced Liver Injury in the United States. Gastroenterology 2008; 135:1924–1934. doi: 10.1053/j.gastro.2008.09.011.
-
(2008)
Gastroenterology
, vol.135
, pp. 1924-1934
-
-
Chalasani, N1
Fontana, RJ2
Bonkovsky, HL3
Watkins, PB4
Davern, T5
Serrano, J6
-
10
-
-
84859913270
-
Drug-induced liver injury
-
Grant LM, Rockey DC. Drug-induced liver injury. Curr Opin Gastroenterol 2012;28:198–202. doi: 10.1097/MOG.0b013e3283528b5d.
-
(2012)
Curr Opin Gastroenterol
, vol.28
, pp. 198-202
-
-
Grant, LM1
Rockey, DC.2
-
11
-
-
84879903935
-
Epidemiology of drug-induced liver injury in China: a systematic analysis of the Chinese literature including 21,789 patients
-
Zhou Y, Yang L, Liao Z, He X, Zhou Y, Guo H. Epidemiology of drug-induced liver injury in China: a systematic analysis of the Chinese literature including 21,789 patients. Eur J Gastroenterol Hepatol 2013;25:825–829. doi: 10.1097/MEG.0b013e32835f6889.
-
(2013)
Eur J Gastroenterol Hepatol
, vol.25
, pp. 825-829
-
-
Zhou, Y1
Yang, L2
Liao, Z3
He, X4
Zhou, Y5
Guo, H.6
-
12
-
-
84861607709
-
SLCO1B1*15 haplotype is associated with rifampin-induced liver injury
-
Li LM, Chen L, Deng GH, Tan WT, Dan YJ, Wang RQ, et al. SLCO1B1*15 haplotype is associated with rifampin-induced liver injury. Mol Med Rep 2012;6:75–82. doi: 10.3892/mmr.2012.900.
-
(2012)
Mol Med Rep
, vol.6
, pp. 75-82
-
-
Li, LM1
Chen, L2
Deng, GH3
Tan, WT4
Dan, YJ5
Wang, RQ6
-
13
-
-
79957523368
-
Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles
-
Lucena MI, Molokhia M, Shen YF, Urban TJ, Aithal GP, Andrade RJ, et al. Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles. Gastroenterology 2011;141:338– 347. doi: 10.1053/j.gastro.2011.04.001.
-
(2011)
Gastroenterology
, vol.141
, pp. 338-347
-
-
Lucena, MI1
Molokhia, M2
Shen, YF3
Urban, TJ4
Aithal, GP5
Andrade, RJ6
-
14
-
-
33645220583
-
Drug-induced liver injury: Summary of a single topic Clinical research conference
-
Watkins PB, Seeff LB. Drug-induced liver injury: Summary of a single topic Clinical research conference. Hepatology 2006;43:618–631. doi: 10.1002/hep.21095.
-
(2006)
Hepatology
, vol.43
, pp. 618-631
-
-
Watkins, PB1
Seeff, LB.2
-
15
-
-
53249086098
-
Women encounter ADRs more often than do men
-
Zopf Y, Rabe C, Neubert A, Gassmann KG, Rascher W, Hahn EG, et al. Women encounter ADRs more often than do men. Eur J Clin Pharmacol 2008;64:999–1004. doi: 10.1007/s00228-008-0494-6.
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 999-1004
-
-
Zopf, Y1
Rabe, C2
Neubert, A3
Gassmann, KG4
Rascher, W5
Hahn, EG6
-
16
-
-
13444305469
-
Idiosyncratic liver injury: Challenges and approaches
-
Watkins PB. Idiosyncratic liver injury: Challenges and approaches. Toxicol Pathol 2005;33:1–5. doi: 10.1080/01926230590888306.
-
(2005)
Toxicol Pathol
, vol.33
, pp. 1-5
-
-
Watkins, PB.1
-
17
-
-
34548732476
-
Isoforms of alanine aminotransferases in human tissues and serum Differential tissue expression using novel antibodies
-
Lindblom P, Rafter I, Copley C, Andersson U, Hedberg JJ, Berg AL, et al. Isoforms of alanine aminotransferases in human tissues and serum Differential tissue expression using novel antibodies. Arch Biochem Biophys 2007;466:66–77. doi: 10.1016/j.abb.2007.07.023.
-
(2007)
Arch Biochem Biophys
, vol.466
, pp. 66-77
-
-
Lindblom, P1
Rafter, I2
Copley, C3
Andersson, U4
Hedberg, JJ5
Berg, AL6
-
18
-
-
70349406480
-
Current Concepts of Mechanisms in Drug-Induced Hepatotoxicity
-
Russmann S, Kullak-Ublick GA, Grattagliano I. Current Concepts of Mechanisms in Drug-Induced Hepatotoxicity. Curr Med Chem 2009;16: 3041–3053. doi: 10.2174/092986709788803097.
-
(2009)
Curr Med Chem
, vol.16
, pp. 3041-3053
-
-
Russmann, S1
Kullak-Ublick, GA2
Grattagliano, I.3
-
19
-
-
77953775529
-
Clinical and Toxicodynamic Evidence that HighDose Pyrazinamide Is Not More Hepatotoxic than the Low Doses Currently Used
-
Pasipanodya JG, Gumbo T. Clinical and Toxicodynamic Evidence that HighDose Pyrazinamide Is Not More Hepatotoxic than the Low Doses Currently Used. Antimicrob Agents Chemother 2010;54:2847–2854. doi: 10.1128/AAC.01567-09.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2847-2854
-
-
Pasipanodya, JG1
Gumbo, T.2
-
20
-
-
70349406480
-
Current concepts of mechanisms in drug-induced hepatotoxicity
-
Russmann S, Kullak-Ublick GA, Grattagliano I. Current concepts of mechanisms in drug-induced hepatotoxicity. Curr Med Chem 2009;16: 3041–3053. doi: 10.2174/092986709788803097.
-
(2009)
Curr Med Chem
, vol.16
, pp. 3041-3053
-
-
Russmann, S1
Kullak-Ublick, GA2
Grattagliano, I.3
-
21
-
-
67651244726
-
Drug-induced liver injury: Is it somehow foreseeable?
-
Tarantino G, Di Minno MND, Capone D. Drug-induced liver injury: Is it somehow foreseeable? World J Gastroenterol 2009;15:2817–2833. doi: 10.3748/wjg.15.2817.
-
(2009)
World J Gastroenterol
, vol.15
, pp. 2817-2833
-
-
Tarantino, G1
Di Minno, MND2
Capone, D.3
-
22
-
-
34548133006
-
Acetaminophen hepatotoxicity
-
vi
-
Larson AM. Acetaminophen hepatotoxicity. Clin Liver Dis 2007;11:525– 548, vi. doi: 10.1016/j.cld.2007.06.006.
-
(2007)
Clin Liver Dis
, vol.11
, pp. 525-548
-
-
Larson, AM.1
-
23
-
-
84869113062
-
Identification of Novel Translational Urinary Biomarkers for Acetaminophen-Induced Acute Liver Injury Using Proteomic Profiling in Mice
-
van Swelm RPL, Laarakkers CMM, van der Kuur EC, Morava-Kozicz E, Wevers RA, Augustijn KD, et al. Identification of Novel Translational Urinary Biomarkers for Acetaminophen-Induced Acute Liver Injury Using Proteomic Profiling in Mice. Plos One 2012;7:e49524. doi: 10.1371/journal. pone.0049524
-
(2012)
Plos One
, vol.7
, pp. e49524
-
-
van Swelm, RPL1
Laarakkers, CMM2
van der Kuur, EC3
Morava-Kozicz, E4
Wevers, RA5
Augustijn, KD6
-
24
-
-
84855833450
-
Endogenous Interleukin-4 Regulates Glutathione Synthesis Following Acetaminophen-Induced Liver Injury in Mice
-
Ryan PM, Bourdi M, Korrapati MC, Proctor WR, Vasquez RA, Yee SB, et al. Endogenous Interleukin-4 Regulates Glutathione Synthesis Following Acetaminophen-Induced Liver Injury in Mice. Chem Res Toxicol 2012;25: 83–93. doi: 10.1021/tx2003992.
-
(2012)
Chem Res Toxicol
, vol.25
, pp. 83-93
-
-
Ryan, PM1
Bourdi, M2
Korrapati, MC3
Proctor, WR4
Vasquez, RA5
Yee, SB6
-
25
-
-
75349095405
-
The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice
-
Martin-Murphy BV, Holt MP, Ju C. The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice. Toxicol Lett 2010;192:387–394. doi: 10.1016/j.toxlet.2009.11.016.
-
(2010)
Toxicol Lett
, vol.192
, pp. 387-394
-
-
Martin-Murphy, BV1
Holt, MP2
Ju, C.3
-
26
-
-
77950620215
-
Lactoferrin Protects Against Acetaminophen-induced Liver Injury in Mice
-
Yin H, Cheng LL, Holt M, Hail N, MacLaren R, Ju C. Lactoferrin Protects Against Acetaminophen-induced Liver Injury in Mice. Hepatology 2010;51: 1007–1016. doi: 10.1002/hep.23476.
-
(2010)
Hepatology
, vol.51
, pp. 1007-1016
-
-
Yin, H1
Cheng, LL2
Holt, M3
Hail, N4
MacLaren, R5
Ju, C.6
-
27
-
-
7444268462
-
Adverse hepatic drug reactions: inflammatory episodes as consequence and contributor
-
Ganey PE, Luyendyk JP, Maddox JF, Roth RA. Adverse hepatic drug reactions: inflammatory episodes as consequence and contributor. Chem Biol Interact 2004;150:35–51. doi: 10.1016/j.cbi.2004.09.002.
-
(2004)
Chem Biol Interact
, vol.150
, pp. 35-51
-
-
Ganey, PE1
Luyendyk, JP2
Maddox, JF3
Roth, RA.4
-
28
-
-
20844444779
-
Idiosyncratic drug hepatotoxicity
-
Kaplowitz N. Idiosyncratic drug hepatotoxicity. Nat Rev Drug Discov 2005; 4:489–499. doi: 10.1038/nrd1750.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 489-499
-
-
Kaplowitz, N.1
-
29
-
-
33847081148
-
Idiosyncratic drug reactions: Current understanding
-
Uetrecht J. Idiosyncratic drug reactions: Current understanding. Annu Rev Pharmacol 2007;47:513–539. doi: 10.1146/annurev.pharmtox.47. 120505.105150.
-
(2007)
Annu Rev Pharmacol
, vol.47
, pp. 513-539
-
-
Uetrecht, J.1
-
30
-
-
67349272258
-
Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity
-
Cosgrove BD, King BM, Hasan MA, Alexopoulos LG, Farazi PA, Hendriks BS, et al. Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity. Toxicol Appl Pharmacol 2009;237:317–330. doi: 10.1016/j.taap.2009.04.002.
-
(2009)
Toxicol Appl Pharmacol
, vol.237
, pp. 317-330
-
-
Cosgrove, BD1
King, BM2
Hasan, MA3
Alexopoulos, LG4
Farazi, PA5
Hendriks, BS6
-
31
-
-
13444302921
-
Do preclinical testing strategies help predict human hepatotoxic potentials
-
Peters TS. Do preclinical testing strategies help predict human hepatotoxic potentials. Toxicol Pathol 2005;33:146–154. doi: 10.1080/019262305905 22121.
-
(2005)
Toxicol Pathol
, vol.33
, pp. 146-154
-
-
Peters, TS.1
-
32
-
-
0042831348
-
Screening for the potential of a drug candidate to cause idiosyncratic drug reactions
-
Uetrecht J. Screening for the potential of a drug candidate to cause idiosyncratic drug reactions. Drug Discov Today 2003;8:832–837. doi: 10.1016/S1359-6446(03)02816-2.
-
(2003)
Drug Discov Today
, vol.8
, pp. 832-837
-
-
Uetrecht, J.1
-
33
-
-
49649102889
-
Glutathione S-transferase M1 and T1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury
-
Lucena MI, Andrade RJ, Martinez C, Ulzurrun E, Garcia-Martin E, Borraz Y, et al. Glutathione S-transferase M1 and T1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury. Hepatology 2008; 48:588–596. doi: 10.1002/hep.22370.
-
(2008)
Hepatology
, vol.48
, pp. 588-596
-
-
Lucena, MI1
Andrade, RJ2
Martinez, C3
Ulzurrun, E4
Garcia-Martin, E5
Borraz, Y6
-
34
-
-
33845666885
-
Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry
-
Andrade RJ, Lucena MI, Kaplowitz N, Garcia-Munoz B, Borraz Y, Pachkoria K, et al. Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry. Hepatology 2006;44:1581–1588. doi: 10.1002/hep.21424.
-
(2006)
Hepatology
, vol.44
, pp. 1581-1588
-
-
Andrade, RJ1
Lucena, MI2
Kaplowitz, N3
Garcia-Munoz, B4
Borraz, Y5
Pachkoria, K6
-
35
-
-
70449117614
-
Immunoallergic Drug-Induced Liver Injury in Humans
-
Uetrecht J. Immunoallergic Drug-Induced Liver Injury in Humans. Semin Liver Dis 2009;29:383–392. doi: 10.1055/s-0029-1240007.
-
(2009)
Semin Liver Dis
, vol.29
, pp. 383-392
-
-
Uetrecht, J.1
-
36
-
-
75449112589
-
Oral Medications with Significant Hepatic Metabolism at Higher Risk for Hepatic Adverse Events
-
Lammert C, Bjornsson E, Niklasson A, Chalasani N. Oral Medications with Significant Hepatic Metabolism at Higher Risk for Hepatic Adverse Events. Hepatology 2010;51:615–620. doi: 10.1002/hep.23317.
-
(2010)
Hepatology
, vol.51
, pp. 615-620
-
-
Lammert, C1
Bjornsson, E2
Niklasson, A3
Chalasani, N.4
-
37
-
-
77951553451
-
Drug-induced liver injury: past, present and future
-
Daly AK. Drug-induced liver injury: past, present and future. Pharmacogenomics 2010;11:607–611. doi: 10.2217/pgs.10.24.
-
(2010)
Pharmacogenomics
, vol.11
, pp. 607-611
-
-
Daly, AK.1
-
38
-
-
67649859295
-
HLAB(star)5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
-
Daly AK, Donaldson PT, Bhatnagar P, Shen YF, Pe’er I, Floratos A, et al. HLAB(star)5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat Genet 2009;41:816–819. doi: 10.1038/ng.379.
-
(2009)
Nat Genet
, vol.41
, pp. 816-819
-
-
Daly, AK1
Donaldson, PT2
Bhatnagar, P3
Shen, YF4
Pe’er, I5
Floratos, A6
-
39
-
-
77955082302
-
A genome-wide study identifies HLA alleles associated with lumiracoxibrelated liver injury
-
Singer JB, Lewitzky S, Leroy E, Yang F, Zhao XJ, Klickstein L, et al. A genome-wide study identifies HLA alleles associated with lumiracoxibrelated liver injury. Nat Genet 2010;42:711–714. doi: 10.1038/ng.632.
-
(2010)
Nat Genet
, vol.42
, pp. 711-714
-
-
Singer, JB1
Lewitzky, S2
Leroy, E3
Yang, F4
Zhao, XJ5
Klickstein, L6
-
40
-
-
33947327550
-
Genetic polymorphisms of CYP2C9 and CYP2C19 are not related to druginduced idiosyncratic liver injury (DILI)
-
Pachkoria K, Lucena MI, Ruiz-Cabello F, Crespo E, Cabello MR, Andrade RJ. Genetic polymorphisms of CYP2C9 and CYP2C19 are not related to druginduced idiosyncratic liver injury (DILI). Brit J Pharmacol 2007;150:808– 815. doi: 10.1038/sj.bjp.0707122.
-
(2007)
Brit J Pharmacol
, vol.150
, pp. 808-815
-
-
Pachkoria, K1
Lucena, MI2
Ruiz-Cabello, F3
Crespo, E4
Cabello, MR5
Andrade, RJ.6
-
41
-
-
71049174955
-
Evaluation of the Potential for Drug-Induced Liver Injury Based on in Vitro Covalent Binding to Human Liver Proteins
-
Usui T, Mise M, Hashizume T, Yabuki M, Komuro S. Evaluation of the Potential for Drug-Induced Liver Injury Based on in Vitro Covalent Binding to Human Liver Proteins. Drug Metab Dispos 2009;37:2383–2392. doi: 10.1124/dmd.109.028860.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 2383-2392
-
-
Usui, T1
Mise, M2
Hashizume, T3
Yabuki, M4
Komuro, S.5
-
42
-
-
47749150312
-
Human N-acetyltransferases and drug-induced hepatotoxicity
-
Makarova SI. Human N-acetyltransferases and drug-induced hepatotoxicity. Curr Drug Metab 2008;9:545. doi: 10.2174/138920008784892047.
-
(2008)
Curr Drug Metab
, vol.9
, pp. 545
-
-
Makarova, SI.1
-
43
-
-
34548124521
-
Causality assessment of drug-induced hepatotoxicity: promises and pitfalls
-
Shapiro MA, Lewis JH. Causality assessment of drug-induced hepatotoxicity: promises and pitfalls. ClinLiver Dis 2007;11:477–505, v. doi: 10.1016/j.cld.2007.06.003.
-
(2007)
ClinLiver Dis
, vol.11
, pp. 477-505
-
-
Shapiro, MA1
Lewis, JH.2
-
44
-
-
77952718055
-
Risk factors for idiosyncratic drug-induced liver injury
-
Chalasani N, Bjornsson E. Risk factors for idiosyncratic drug-induced liver injury. Gastroenterology 2010;138:2246–59. doi: 10.1053/j.gastro.2010.04.001.
-
(2010)
Gastroenterology
, vol.138
, pp. 2246-2259
-
-
Chalasani, N1
Bjornsson, E.2
-
45
-
-
64049090993
-
Practical guidelines for diagnosis and early management of drug-induced liver injury
-
Tajiri K, Shimizu Y. Practical guidelines for diagnosis and early management of drug-induced liver injury. World J Gastroenterol 2008;14:6774–6785. doi: 10.3748/wjg.14.6774.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 6774-6785
-
-
Tajiri, K1
Shimizu, Y.2
-
46
-
-
84866611283
-
A Paper-Based Multiplexed Transaminase Test for Low-Cost, Point-of-Care Liver Function Testing
-
Pollock NR, Rolland JP, Kumar S, Beattie PD, Jain S, Noubary F, et al. A Paper-Based Multiplexed Transaminase Test for Low-Cost, Point-of-Care Liver Function Testing. Sci Transl Med 2012;4:152ra129. doi: 10.1126/scitranslmed.3003981.
-
(2012)
Sci Transl Med
, vol.4
, pp. 152ra129
-
-
Pollock, NR1
Rolland, JP2
Kumar, S3
Beattie, PD4
Jain, S5
Noubary, F6
-
47
-
-
16644401688
-
Aminotransferase changes and acute hepatitis in patients with dengue fever: analysis of 1,585 cases
-
Souza LJ, Alves JG, Nogueira RM, Gicovate Neto C, Bastos DA, Siqueira EW, et al. Aminotransferase changes and acute hepatitis in patients with dengue fever: analysis of 1,585 cases. Braz J Infect Dis 2004;8:156–163. doi: 10.1590/S1413-86702004000200006.
-
(2004)
Braz J Infect Dis
, vol.8
, pp. 156-163
-
-
Souza, LJ1
Alves, JG2
Nogueira, RM3
Gicovate Neto, C4
Bastos, DA5
Siqueira, EW6
-
48
-
-
0026794552
-
Liver biochemical tests and dengue fever
-
Kuo CH, Tai DI, Chang-Chien CS, Lan CK, Chiou SS, Liaw YF. Liver biochemical tests and dengue fever. Am JTrop Med Hyg 1992;47:265–270.
-
(1992)
Am JTrop Med Hyg
, vol.47
, pp. 265-270
-
-
Kuo, CH1
Tai, DI2
Chang-Chien, CS3
Lan, CK4
Chiou, SS5
Liaw, YF.6
-
49
-
-
84873937303
-
Drug-induced liver injury in hospitalized patients with notably elevated alanine aminotransferase
-
Xu HM, Chen Y, Xu J, Zhou Q. Drug-induced liver injury in hospitalized patients with notably elevated alanine aminotransferase. World J Gastroenterol 2012; 18:5972–2978. doi: 10.3748/wjg.v18.i41.5972.
-
(2012)
World J Gastroenterol
, vol.18
, pp. 5972-2978
-
-
Xu, HM1
Chen, Y2
Xu, J3
Zhou, Q.4
-
51
-
-
84877585028
-
DILI: New Insights into Diagnosis and Management
-
Tran T, Lee WM. DILI: New Insights into Diagnosis and Management. Curr Hepat Rep 2013;12:53–58. doi: 10.1007/s11901-012-0159-x.
-
(2013)
Curr Hepat Rep
, vol.12
, pp. 53-58
-
-
Tran, T1
Lee, WM.2
-
53
-
-
12844268517
-
Serum alanine aminotransferase in skeletal muscle diseases
-
Nathwani RA, Pais S, Reynolds TB, Kaplowitz N. Serum alanine aminotransferase in skeletal muscle diseases. Hepatology 2005;41:380–382. doi: 10.1002/hep.20548.
-
(2005)
Hepatology
, vol.41
, pp. 380-382
-
-
Nathwani, RA1
Pais, S2
Reynolds, TB3
Kaplowitz, N.4
-
54
-
-
64149089648
-
Elevated alanine aminotransferase levels associated with polymyositis: can this be due to muscle injury?
-
Shabaneh Al-Tamimi HA, McDonald R. Elevated alanine aminotransferase levels associated with polymyositis: can this be due to muscle injury? J Clin Rheumatol 2008;14:363–364. doi: 10.1097/RHU.0b013e318190b4a6.
-
(2008)
J Clin Rheumatol
, vol.14
, pp. 363-364
-
-
Shabaneh Al-Tamimi, HA1
McDonald, R.2
-
55
-
-
0033153457
-
Treatment of acetaminophen overdose
-
quiz 1091-1093
-
Zed PJ, Krenzelok EP. Treatment of acetaminophen overdose. Am J Health Syst Pharm 1999;56:1081–1091; quiz 1091-1093.
-
(1999)
Am J Health Syst Pharm
, vol.56
, pp. 1081-1091
-
-
Zed, PJ1
Krenzelok, EP.2
-
56
-
-
7444231518
-
A gene expression signature for oxidant stress/reactive metabolites in rat liver
-
McMillian M, Nie AY, Parker JB, Leone A, Bryant S, Kemmerer M, et al. A gene expression signature for oxidant stress/reactive metabolites in rat liver. Biochem Pharmacol 2004;68:2249–2261. doi: 10.1016/j.bcp.2004.08.003.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 2249-2261
-
-
McMillian, M1
Nie, AY2
Parker, JB3
Leone, A4
Bryant, S5
Kemmerer, M6
-
57
-
-
67649211924
-
Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy
-
Hirode M, Omura K, Kiyosawa N, Uehara T, Shimuzu T, Ono A, et al. Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy. J Toxicol Sci 2009;34:281–293. doi: 10.2131/jts.34.281.
-
(2009)
J Toxicol Sci
, vol.34
, pp. 281-293
-
-
Hirode, M1
Omura, K2
Kiyosawa, N3
Uehara, T4
Shimuzu, T5
Ono, A6
-
58
-
-
39649094514
-
The current state of serum biomarkers of hepatotoxicity
-
Ozer J, Ratner M, Shaw M, Bailey W, Schomaker S. The current state of serum biomarkers of hepatotoxicity. Toxicology 2008;245:194–205. doi: 10.1016/j.tox.2007.11.021.
-
(2008)
Toxicology
, vol.245
, pp. 194-205
-
-
Ozer, J1
Ratner, M2
Shaw, M3
Bailey, W4
Schomaker, S.5
-
59
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281–297. doi: 10.1016/S0092-8674(04)00045-5.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, DP.1
-
60
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75:843–854. doi: 10.1016/0092-8674(93)90529-Y.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, RC1
Feinbaum, RL2
Ambros, V.3
-
61
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009;136:215–233. doi: 10.1016/j.cell.2009.01.002.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, DP.1
-
62
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V. The functions of animal microRNAs. Nature 2004;431:350–355. doi: 10.1038/nature02871.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
63
-
-
0038343499
-
MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing
-
Ambros V. MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 2003;113:673–676. doi: 10.1016/S00928674(03)00428-8.
-
(2003)
Cell
, vol.113
, pp. 673-676
-
-
Ambros, V.1
-
64
-
-
43449102192
-
Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
-
Lawrie CH, Gal S, Dunlop HM, Pushkaran B, Liggins AP, Pulford K, et al. Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Brit J Haematol 2008;141: 672–675. doi: 10.1111/j.1365-2141.2008.07077.x.
-
(2008)
Brit J Haematol
, vol.141
, pp. 672-675
-
-
Lawrie, CH1
Gal, S2
Dunlop, HM3
Pushkaran, B4
Liggins, AP5
Pulford, K6
-
65
-
-
48749122914
-
Circulating microRNAs as stable blood-based markers for cancer detection
-
Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, PogosovaAgadjanyan EL, et al. Circulating microRNAs as stable blood-based markers for cancer detection. P Natl Acad Sci U S A 2008;105:10513–10518. doi: 10.1073/pnas.0804549105.
-
(2008)
P Natl Acad Sci U S A
, vol.105
, pp. 10513-10518
-
-
Mitchell, PS1
Parkin, RK2
Kroh, EM3
Fritz, BR4
Wyman, SK5
PogosovaAgadjanyan, EL6
-
66
-
-
53349177819
-
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
-
Chen X, Ba Y, Ma LJ, Cai X, Yin Y, Wang KH, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 2008;18:997–1006. doi: 10.1038/cr.2008.282.
-
(2008)
Cell Res
, vol.18
, pp. 997-1006
-
-
Chen, X1
Ba, Y2
Ma, LJ3
Cai, X4
Yin, Y5
Wang, KH6
-
67
-
-
52349083651
-
Serum microRNAs are promising novel biomarkers
-
Gilad S, Meiri E, Yogev Y, Benjamin S, Lebanony D, Yerushalmi N, et al. Serum microRNAs are promising novel biomarkers. Plos One 2008;3: e3148. doi: 10.1371/journal.pone.0003148.
-
(2008)
Plos One
, vol.3
, pp. e3148
-
-
Gilad, S1
Meiri, E2
Yogev, Y3
Benjamin, S4
Lebanony, D5
Yerushalmi, N6
-
68
-
-
67650711156
-
MicroRNAs in Cancer
-
Garzon R, Calin GA, Croce CM. MicroRNAs in Cancer. Annu Rev Med 2009; 60:167–179. doi: 10.1146/annurev.med.59.053006.104707.
-
(2009)
Annu Rev Med
, vol.60
, pp. 167-179
-
-
Garzon, R1
Calin, GA2
Croce, CM.3
-
69
-
-
66049112674
-
Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening
-
Ng E, Chong W, Jin H, Lam E, Shin V, Yu J, et al. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 2009;58:1375–1381. doi: 10.1136/gut.2008.167817.
-
(2009)
Gut
, vol.58
, pp. 1375-1381
-
-
Ng, E1
Chong, W2
Jin, H3
Lam, E4
Shin, V5
Yu, J6
-
70
-
-
84863259319
-
Circulating microRNAs: a novel class of biomarkers to diagnose and monitor human cancers
-
Zen K, Zhang C. Circulating microRNAs: a novel class of biomarkers to diagnose and monitor human cancers. Med Res Rev 2012;32:326–348. doi: 10.1002/med.20215.
-
(2012)
Med Res Rev
, vol.32
, pp. 326-348
-
-
Zen, K1
Zhang, C.2
-
71
-
-
84872142803
-
Exploring microRNA biomarkers for disease monitoring and response to therapy
-
Tung J. Exploring microRNA biomarkers for disease monitoring and response to therapy. Bioanalysis 2012;4:2204.
-
(2012)
Bioanalysis
, vol.4
, pp. 2204
-
-
Tung, J.1
-
72
-
-
35648945351
-
Changes of microRNA expression in rat liver treated by acetaminophen or carbon tetrachloride– regulating role of micro-RNA for RNA expression
-
Fukushima T, Hamada Y, Yamada H, Horii I. Changes of microRNA expression in rat liver treated by acetaminophen or carbon tetrachloride– regulating role of micro-RNA for RNA expression. J Toxicol Sci 2007;32: 401–409. doi: 10.2131/jts.32.401.
-
(2007)
J Toxicol Sci
, vol.32
, pp. 401-409
-
-
Fukushima, T1
Hamada, Y2
Yamada, H3
Horii, I.4
-
73
-
-
34247164636
-
Induction of microRNAome deregulation in rat liver by longterm tamoxifen exposure
-
Pogribny IP, Tryndyak VP, Boyko A, Rodriguez-Juarez R, Beland FA, Kovalchuk O. Induction of microRNAome deregulation in rat liver by longterm tamoxifen exposure. Mutat Res 2007;619:30–37. doi: 10.1016/j.mrfmmm.2006.12.006.
-
(2007)
Mutat Res
, vol.619
, pp. 30-37
-
-
Pogribny, IP1
Tryndyak, VP2
Boyko, A3
Rodriguez-Juarez, R4
Beland, FA5
Kovalchuk, O.6
-
74
-
-
80051699704
-
Involvement of microRNAs in dioxin-induced liver damage in the mouse
-
Yoshioka W, Higashiyama W, Tohyama C. Involvement of microRNAs in dioxin-induced liver damage in the mouse. Toxicol Sci 2011;122:457–465. doi: 10.1093/toxsci/kfr130.
-
(2011)
Toxicol Sci
, vol.122
, pp. 457-465
-
-
Yoshioka, W1
Higashiyama, W2
Tohyama, C.3
-
75
-
-
84897835125
-
Involvement of miRNAs in the early phase of halothane-induced liver injury
-
Endo S, Yano A, Fukami T, Nakajima M, Yokoi T. Involvement of miRNAs in the early phase of halothane-induced liver injury. Toxicology 2014;319:75– 84. doi: 10.1016/j.tox.2014.02.011.
-
(2014)
Toxicology
, vol.319
, pp. 75-84
-
-
Endo, S1
Yano, A2
Fukami, T3
Nakajima, M4
Yokoi, T.5
-
76
-
-
33749487425
-
MicroRNA regulates the expression of human cytochrome P450 1B1
-
Tsuchiya Y, Nakajima M, Takagi S, Taniya T, Yokoi T. MicroRNA regulates the expression of human cytochrome P450 1B1. Cancer Res 2006;66:9090– 9098. doi: 10.1158/0008-5472.CAN-06-1403.
-
(2006)
Cancer Res
, vol.66
, pp. 9090-9098
-
-
Tsuchiya, Y1
Nakajima, M2
Takagi, S3
Taniya, T4
Yokoi, T.5
-
77
-
-
70349333224
-
Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b
-
Komagata S, Nakajima M, Takagi S, Mohri T, Taniya T, Yokoi T. Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b. Mol Pharmacol 2009;76:702–709. doi: 10.1124/mol.109.056986.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 702-709
-
-
Komagata, S1
Nakajima, M2
Takagi, S3
Mohri, T4
Taniya, T5
Yokoi, T.6
-
78
-
-
80052469129
-
Toxicological implications of modulation of gene expression by microRNAs
-
Yokoi T, Nakajima M. Toxicological implications of modulation of gene expression by microRNAs. Toxicol Sci 2011;123:1–14. doi: 10.1093/toxsci/kfr168.
-
(2011)
Toxicol Sci
, vol.123
, pp. 1-14
-
-
Yokoi, T1
Nakajima, M.2
-
79
-
-
84872259086
-
microRNAs as mediators of drug toxicity
-
Yokoi T, Nakajima M. microRNAs as mediators of drug toxicity. Annu Rev Pharmacol Toxicol 2013;53:377–400. doi: 10.1146/annurev-pharmtox011112-140250.
-
(2013)
Annu Rev Pharmacol Toxicol
, vol.53
, pp. 377-400
-
-
Yokoi, T1
Nakajima, M.2
-
80
-
-
63149121152
-
Circulating microRNAs, potential biomarkers for drug-induced liver injury
-
Wang K, Zhang S, Marzolf B, Troisch P, Brightman A, Hu Z, et al. Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc Natl Acad Sci U S A 2009;106:4402–4407. doi: 10.1073/pnas.0813371106.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4402-4407
-
-
Wang, K1
Zhang, S2
Marzolf, B3
Troisch, P4
Brightman, A5
Hu, Z6
-
81
-
-
78649837734
-
Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases
-
Zhang Y, Jia Y, Zheng R, Guo Y, Wang Y, Guo H, et al. Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases. Clin Chem 2010;56:1830–1838. doi: 10.1373/clinchem.2010.147850.
-
(2010)
Clin Chem
, vol.56
, pp. 1830-1838
-
-
Zhang, Y1
Jia, Y2
Zheng, R3
Guo, Y4
Wang, Y5
Guo, H6
-
82
-
-
84868211262
-
Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases
-
Bala S, Petrasek J, Mundkur S, Catalano D, Levin I, Ward J, et al. Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. Hepatology 2012;56:1946–1957. doi: 10.1002/hep.25873.
-
(2012)
Hepatology
, vol.56
, pp. 1946-1957
-
-
Bala, S1
Petrasek, J2
Mundkur, S3
Catalano, D4
Levin, I5
Ward, J6
-
83
-
-
84863087125
-
Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: a research study
-
Ward J, Bala S, Petrasek J, Szabo G. Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: a research study. World J Gastroenterol 2012;18:2798–2804. doi: 10.3748/wjg.v18.i22.2798.
-
(2012)
World J Gastroenterol
, vol.18
, pp. 2798-2804
-
-
Ward, J1
Bala, S2
Petrasek, J3
Szabo, G.4
-
84
-
-
84875826688
-
Hopes and challenges in using miRNAs as translational biomarkers for drug-induced liver injury
-
Shi Q, Yang X, Mendrick DL. Hopes and challenges in using miRNAs as translational biomarkers for drug-induced liver injury. Biomark Med 2013; 7:307–315. doi: 10.2217/bmm.13.9.
-
(2013)
Biomark Med
, vol.7
, pp. 307-315
-
-
Shi, Q1
Yang, X2
Mendrick, DL.3
-
85
-
-
84857166172
-
Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis
-
Yamaura Y, Nakajima M, Takagi S, Fukami T, Tsuneyama K, Yokoi T. Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis. Plos One 2012;7:e30250. doi: 10.1371/journal.pone.0030250.
-
(2012)
Plos One
, vol.7
, pp. e30250
-
-
Yamaura, Y1
Nakajima, M2
Takagi, S3
Fukami, T4
Tsuneyama, K5
Yokoi, T.6
-
86
-
-
84862070687
-
A panel of serum microRNAs as specific biomarkers for diagnosis of compound-and herbinduced liver injury in rats
-
Su YW, Chen X, Jiang ZZ, Wang T, Wang C, Zhang Y, et al. A panel of serum microRNAs as specific biomarkers for diagnosis of compound-and herbinduced liver injury in rats. Plos One 2012;7:e37395. doi: 10.1371/journal.pone.0037395.
-
(2012)
Plos One
, vol.7
, pp. e37395
-
-
Su, YW1
Chen, X2
Jiang, ZZ3
Wang, T4
Wang, C5
Zhang, Y6
-
87
-
-
84875846434
-
Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats
-
Starckx S, Batheja A, Verheyen GR, Jonghe SD, Steemans K, Dijck BV, et al. Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats. Toxicol Pathol 2013;41:795–804. doi: 10.1177/0192623312464436.
-
(2013)
Toxicol Pathol
, vol.41
, pp. 795-804
-
-
Starckx, S1
Batheja, A2
Verheyen, GR3
Jonghe, SD4
Steemans, K5
Dijck, BV6
-
88
-
-
78149484489
-
The microRNA spectrum in 12 body fluids
-
Weber JA, Baxter DH, Zhang S, Huang DY, Huang KH, Lee MJ, et al. The microRNA spectrum in 12 body fluids. Clin Chem 2010;56:1733–1741. doi: 10.1373/clinchem.2010.147405.
-
(2010)
Clin Chem
, vol.56
, pp. 1733-1741
-
-
Weber, JA1
Baxter, DH2
Zhang, S3
Huang, DY4
Huang, KH5
Lee, MJ6
-
89
-
-
84862019046
-
Circulating and urinary microRNAs in kidney disease
-
Lorenzen JM, Thum T. Circulating and urinary microRNAs in kidney disease. Clin J Am Soc Nephrol 2012;7:1528–1533. doi: 10.2215/CJN.01170212.
-
(2012)
Clin J Am Soc Nephrol
, vol.7
, pp. 1528-1533
-
-
Lorenzen, JM1
Thum, T.2
-
90
-
-
84867811724
-
Cell-free microRNAs in urine as diagnostic and prognostic biomarkers of bladder cancer
-
Yun SJ, Jeong P, Kim WT, Kim TH, Lee YS, Song PH, et al. Cell-free microRNAs in urine as diagnostic and prognostic biomarkers of bladder cancer. Int J Oncol 2012;41:1871–1878. doi: 10.3892/ijo.2012.1622.
-
(2012)
Int J Oncol
, vol.41
, pp. 1871-1878
-
-
Yun, SJ1
Jeong, P2
Kim, WT3
Kim, TH4
Lee, YS5
Song, PH6
-
91
-
-
84862954550
-
Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity
-
Yang X, Greenhaw J, Shi Q, Su Z, Qian F, Davis K, et al. Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity. Toxicol Sci 2012;125:335–344. doi: 10.1093/toxsci/kfr321.
-
(2012)
Toxicol Sci
, vol.125
, pp. 335-344
-
-
Yang, X1
Greenhaw, J2
Shi, Q3
Su, Z4
Qian, F5
Davis, K6
-
92
-
-
80055038826
-
Circulating microRNAs as potential markers of human drug-induced liver injury
-
Starkey Lewis PJ, Dear J, Platt V, Simpson KJ, Craig DG, Antoine DJ, et al. Circulating microRNAs as potential markers of human drug-induced liver injury. Hepatology 2011;54:1767–1776. doi: 10.1002/hep.24538.
-
(2011)
Hepatology
, vol.54
, pp. 1767-1776
-
-
Starkey Lewis, PJ1
Dear, J2
Platt, V3
Simpson, KJ4
Craig, DG5
Antoine, DJ6
-
93
-
-
84858081410
-
Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans
-
Jetten MJ, Gaj S, Ruiz-Aracama A, de Kok TM, van Delft JH, Lommen A, et al. ’Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans. Toxicol Appl Pharmacol 2012;259:320– 328. doi: 10.1016/j.taap.2012.01.009.
-
(2012)
Toxicol Appl Pharmacol
, vol.259
, pp. 320-328
-
-
Jetten, MJ1
Gaj, S2
Ruiz-Aracama, A3
de Kok, TM4
van Delft, JH5
Lommen, A6
-
94
-
-
84881027019
-
Mechanistic biomarkers provide early and sensitive detection of acetaminopheninduced acute liver injury at first presentation to hospital
-
Antoine DJ, Dear JW, Lewis PS, Platt V, Coyle J, Masson M, et al. Mechanistic biomarkers provide early and sensitive detection of acetaminopheninduced acute liver injury at first presentation to hospital. Hepatology 2013;58:777–787. doi: 10.1002/hep.26294.
-
(2013)
Hepatology
, vol.58
, pp. 777-787
-
-
Antoine, DJ1
Dear, JW2
Lewis, PS3
Platt, V4
Coyle, J5
Masson, M6
-
95
-
-
84893665111
-
Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts
-
Thulin P, Nordahl G, Gry M, Yimer G, Aklillu E, Makonnen E, et al. Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts. Liver Int 2014;34:367–378. doi: 10.1111/liv.12322
-
(2014)
Liver Int
, vol.34
, pp. 367-378
-
-
Thulin, P1
Nordahl, G2
Gry, M3
Yimer, G4
Aklillu, E5
Makonnen, E6
-
96
-
-
84860744644
-
Circulating microRNA122 as a potential biomarker for liver injury
-
Ding XF, Ding JV, Ning J, Yi F, Chen JK, Zhao DY, et al. Circulating microRNA122 as a potential biomarker for liver injury. Mol Med Rep 2012;5:1428– 1432. doi: 10.3892/mmr.2012.838.
-
(2012)
Mol Med Rep
, vol.5
, pp. 1428-1432
-
-
Ding, XF1
Ding, JV2
Ning, J3
Yi, F4
Chen, JK5
Zhao, DY6
-
97
-
-
33645075443
-
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
-
Esau C, Davis S, Murray SF, Yu XX, Pandey SK, Pear M, et al. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab 2006;3:87–98. doi: 10.1016/j.cmet.2006.01.005.
-
(2006)
Cell Metab
, vol.3
, pp. 87-98
-
-
Esau, C1
Davis, S2
Murray, SF3
Yu, XX4
Pandey, SK5
Pear, M6
-
98
-
-
28444469246
-
Silencing of microRNAs in vivo with ‘antagomirs’
-
Krutzfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, et al. Silencing of microRNAs in vivo with ‘antagomirs’. Nature 2005;438:685– 689. doi: 10.1038/nature04303.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J1
Rajewsky, N2
Braich, R3
Rajeev, KG4
Tuschl, T5
Manoharan, M6
-
99
-
-
24644483623
-
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
-
Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P. Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 2005;309:1577–1581. doi: 10.1126/science.1113329.
-
(2005)
Science
, vol.309
, pp. 1577-1581
-
-
Jopling, CL1
Yi, M2
Lancaster, AM3
Lemon, SM4
Sarnow, P.5
-
100
-
-
84871205828
-
Reference genes for real-time PCR quantification of microRNAs and messenger RNAs in rat models of hepatotoxicity
-
Lardizabal MN, Nocito AL, Daniele SM, Ornella LA, Palatnik JF, Veggi LM. Reference genes for real-time PCR quantification of microRNAs and messenger RNAs in rat models of hepatotoxicity. Plos One 2012;7: e36323. doi: 10.1371/journal.pone.0036323.
-
(2012)
Plos One
, vol.7
, pp. e36323
-
-
Lardizabal, MN1
Nocito, AL2
Daniele, SM3
Ornella, LA4
Palatnik, JF5
Veggi, LM.6
-
101
-
-
84884700735
-
Identification of endogenous reference genes for RT-qPCR analysis of plasma microRNAs levels in rats with acetaminophen-induced hepatotoxicity
-
Wang Y, Tang N, Hui T, Wang S, Zeng X, Li H, et al. Identification of endogenous reference genes for RT-qPCR analysis of plasma microRNAs levels in rats with acetaminophen-induced hepatotoxicity. J Appl Toxicol 2013;33:1330–1336. doi: 10.1002/jat.2864.
-
(2013)
J Appl Toxicol
, vol.33
, pp. 1330-1336
-
-
Wang, Y1
Tang, N2
Hui, T3
Wang, S4
Zeng, X5
Li, H6
|