-
2
-
-
13444305469
-
Idiosyncratic liver injury: Challenges and approaches
-
Watkins PB. Idiosyncratic liver injury: challenges and approaches. Toxicol Pathol 2005;33:1-5.
-
(2005)
Toxicol Pathol
, vol.33
, pp. 1-5
-
-
Watkins, P.B.1
-
3
-
-
19544369808
-
Drug-induced liver injury network (DILIN)
-
Hoofnagle JH, Drug-induced liver injury network (DILIN). HEPATOLOGY 2004;40:773.
-
(2004)
Hepatology
, vol.40
, pp. 773
-
-
Hoofnagle, J.H.1
-
4
-
-
0027362542
-
Causality assessment of adverse reactions to drugs-I. A novel method based on the conclusions of international consensus meetings: Application to drug-induced liver injuries
-
Danan G, Benichou C. Causality assessment of adverse reactions to drugs-I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries. J Clin Epidemiol 1993;46:1323-1330.
-
(1993)
J Clin Epidemiol
, vol.46
, pp. 1323-1330
-
-
Danan, G.1
Benichou, C.2
-
5
-
-
18744395784
-
Incidence of drug-induced liver injury in medical inpatients
-
Meier Y, et al. Incidence of drug-induced liver injury in medical inpatients. Eur J Clin Pharmacol 2005;61:135-143.
-
(2005)
Eur J Clin Pharmacol
, vol.61
, pp. 135-143
-
-
Meier, Y.1
-
6
-
-
0036844835
-
Prospective surveillance of acute serious liver disease unrelated to infectious, obstructive, or metabolic diseases: Epidemiological and clinical features, and exposure to drugs
-
Ibanez L, Perez E, Vidal X, Laporte JR, Group d'Estudi Multicenteric d'Hepatotoxicitat Aguda de Barcelona (GEMHAB). Prospective surveillance of acute serious liver disease unrelated to infectious, obstructive, or metabolic diseases: epidemiological and clinical features, and exposure to drugs. J Hepatol 2002;37:592-600.
-
(2002)
J Hepatol
, vol.37
, pp. 592-600
-
-
Ibanez, L.1
Perez, E.2
Vidal, X.3
Laporte, J.R.4
-
7
-
-
33645242067
-
Suspected drug-induced liver fatalities reported to the WHO database
-
Bjornsson E, Olsson R. Suspected drug-induced liver fatalities reported to the WHO database. Dig Liver Dis 2005;38:33-38.
-
(2005)
Dig Liver Dis
, vol.38
, pp. 33-38
-
-
Bjornsson, E.1
Olsson, R.2
-
8
-
-
18744376412
-
Drug-induced liver injury: An analysis of 461 incidences submitted to the Spanish registry over a 10-year period
-
Andrade RJ, Lucerna MI, Fernandez MC, Pelaez G, Pachkoria K, Garcia-Ruiz E, et al. Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period. Gastroenterology 2005;129:512-521.
-
(2005)
Gastroenterology
, vol.129
, pp. 512-521
-
-
Andrade, R.J.1
Lucerna, M.I.2
Fernandez, M.C.3
Pelaez, G.4
Pachkoria, K.5
Garcia-Ruiz, E.6
-
9
-
-
23044473682
-
Outcome and prognostic markers in severe drug-induced liver disease
-
Bjornsson E, Olsson R. Outcome and prognostic markers in severe drug-induced liver disease. HEPATOLOGY 2005;42:481-489.
-
(2005)
Hepatology
, vol.42
, pp. 481-489
-
-
Bjornsson, E.1
Olsson, R.2
-
10
-
-
33645219214
-
Liver disease due to drugs
-
Feldman M, Friedman LS, Sleisenger MH, eds. Philadelphia: Saunders
-
Teoh N, Farrell GC. Liver disease due to drugs. In: Feldman M, Friedman LS, Sleisenger MH, eds. Gastrointestinal and Liver Disease. 8th edition. Philadelphia: Saunders. 2003:730-737.
-
(2003)
Gastrointestinal and Liver Disease. 8th Edition
, pp. 730-737
-
-
Teoh, N.1
Farrell, G.C.2
-
11
-
-
0009082453
-
Drug induced liver disease
-
Schiff ER, Maddrey WC, eds. New York: Lippincott, Williams & Wilkins
-
Chitturi SF, Drug induced liver disease. In Schiff ER, Maddrey WC, eds. Diseases of the Liver. New York: Lippincott, Williams & Wilkins, 2006:1059-1127.
-
(2006)
Diseases of the Liver
, pp. 1059-1127
-
-
Chitturi, S.F.1
-
14
-
-
0037126649
-
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States
-
Ostapowicz G, Fontana RJ, Schiodt FV, Larson A, Davern TJ, Han SH, et al. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 2002;137:947-954.
-
(2002)
Ann Intern Med
, vol.137
, pp. 947-954
-
-
Ostapowicz, G.1
Fontana, R.J.2
Schiodt, F.V.3
Larson, A.4
Davern, T.J.5
Han, S.H.6
-
15
-
-
0041342015
-
Drug-induced hepatotoxicity
-
Lee WM. Drug-induced hepatotoxicity. N Engl J Med 2003;349:474-485.
-
(2003)
N Engl J Med
, vol.349
, pp. 474-485
-
-
Lee, W.M.1
-
16
-
-
3042738919
-
Acetaminophen and the U.S. Acute Liver Failure Study Group: Lowering the risks of hepatic failure
-
Lee WM. Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure. HEPATOLOGY 2004;40:6-9.
-
(2004)
Hepatology
, vol.40
, pp. 6-9
-
-
Lee, W.M.1
-
17
-
-
32644474169
-
Acetaminophen-induced acute liver failure: Results of a United States multi-center, prospective study
-
Larson AM, Polson J, Fontana RJ, Davern TJ, Lalani E, Hynana LS, et al. Acetaminophen-induced acute liver failure: Results of a United States multi-center, prospective study. HEPATOLOGY 2005;42:1364-72.
-
(2005)
Hepatology
, vol.42
, pp. 1364-1372
-
-
Larson, A.M.1
Polson, J.2
Fontana, R.J.3
Davern, T.J.4
Lalani, E.5
Hynana, L.S.6
-
18
-
-
33644868070
-
Measurement of serum acetaminophen-protein adducts in patients with acute liver failure
-
In press
-
Davern TJ, James LP, Hinson JA, Polson J, Larson AM, Fontana RJ, et al. Measurement of serum acetaminophen-protein adducts in patients with acute liver failure. Gastroenterology 2006. In press.
-
(2006)
Gastroenterology
-
-
Davern, T.J.1
James, L.P.2
Hinson, J.A.3
Polson, J.4
Larson, A.M.5
Fontana, R.J.6
-
19
-
-
0036900361
-
Surveillance for fatal suspected adverse drug reactions in the UK
-
Clarkson A, Choonara I. Surveillance for fatal suspected adverse drug reactions in the UK. Arch Dis Child 2002;87:462-466.
-
(2002)
Arch Dis Child
, vol.87
, pp. 462-466
-
-
Clarkson, A.1
Choonara, I.2
-
20
-
-
0023881601
-
Adverse drug reactions in children leading to hospital admission
-
Mitchell AA, Lacouture PG, Sheehan JE, Kauffman RE, Shapiro S. Adverse drug reactions in children leading to hospital admission. Pediatrics 1988;82:24-29.
-
(1988)
Pediatrics
, vol.82
, pp. 24-29
-
-
Mitchell, A.A.1
Lacouture, P.G.2
Sheehan, J.E.3
Kauffman, R.E.4
Shapiro, S.5
-
21
-
-
3242706911
-
Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants
-
Ginsberg G, Hattis D, Sonawane B. Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants. Toxicol Appl Pharmacol 2004;198:164-183.
-
(2004)
Toxicol Appl Pharmacol
, vol.198
, pp. 164-183
-
-
Ginsberg, G.1
Hattis, D.2
Sonawane, B.3
-
22
-
-
0024584277
-
Diagnosis of sulfonamide hypersensitivity reactions by in-vitro "rechallenge" with hydroxylamine metabolites
-
Rieder MJ, Uetrecht J, Shear NH, Cannon M, Miller M, Spielberg SP. Diagnosis of sulfonamide hypersensitivity reactions by in-vitro "rechallenge" with hydroxylamine metabolites. Ann Intern Med 1989;110:286-289.
-
(1989)
Ann Intern Med
, vol.110
, pp. 286-289
-
-
Rieder, M.J.1
Uetrecht, J.2
Shear, N.H.3
Cannon, M.4
Miller, M.5
Spielberg, S.P.6
-
23
-
-
0033390357
-
Anticonvulsant hypersensitivity syndrome: Incidence, prevention and management
-
Knowles SR, Shapiro LE, Shear NH. Anticonvulsant hypersensitivity syndrome: incidence, prevention and management. Drug Saf 1999;21:489-4501.
-
(1999)
Drug Saf
, vol.21
, pp. 489-4501
-
-
Knowles, S.R.1
Shapiro, L.E.2
Shear, N.H.3
-
24
-
-
0030857188
-
Valproate-induced liver failure in one of two siblings with Alpers disease
-
Schwabe MJ, Dobyns WB, Burke B, Armstrong L. Valproate-induced liver failure in one of two siblings with Alpers disease. Pediatr Neurol 1997;16:337-343.
-
(1997)
Pediatr Neurol
, vol.16
, pp. 337-343
-
-
Schwabe, M.J.1
Dobyns, W.B.2
Burke, B.3
Armstrong, L.4
-
25
-
-
0034047901
-
Unintentional acetaminophen ingestion in children and the potential for hepatotoxicity
-
Caravati EM. Unintentional acetaminophen ingestion in children and the potential for hepatotoxicity. J Toxicol Clin Toxicol 2000;38:291-296.
-
(2000)
J Toxicol Clin Toxicol
, vol.38
, pp. 291-296
-
-
Caravati, E.M.1
-
26
-
-
0004039221
-
-
Philadelphia: Lippincott, Williams & Williams
-
Zimmerman H. Hepatotoxicity. Philadelphia: Lippincott, Williams & Williams, 1999.
-
(1999)
Hepatotoxicity
-
-
Zimmerman, H.1
-
27
-
-
0037380862
-
Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis
-
Huang YS, Chem HD, Su WJ, Wu JC, Chang SC, Chiang CH, et al. Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis. HEPATOLOGY 2003;37:924-930.
-
(2003)
Hepatology
, vol.37
, pp. 924-930
-
-
Huang, Y.S.1
Chem, H.D.2
Su, W.J.3
Wu, J.C.4
Chang, S.C.5
Chiang, C.H.6
-
28
-
-
78651188093
-
The carcinogenic activities of certain halogen derivatives of 4-dimethylaminoazobenzene in the rat
-
Miller JA, Sapp RW, Miller EC. The carcinogenic activities of certain halogen derivatives of 4-dimethylaminoazobenzene in the rat. Cancer Res 1949;9:652-660.
-
(1949)
Cancer Res
, vol.9
, pp. 652-660
-
-
Miller, J.A.1
Sapp, R.W.2
Miller, E.C.3
-
29
-
-
0015754446
-
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo
-
Jollow DJ, Mitchell JR, Potter WZ, Davis DL, Gillette JR, Brodie BB. Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. J Pharmacol Exp Ther 1973;187:195-202.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 195-202
-
-
Jollow, D.J.1
Mitchell, J.R.2
Potter, W.Z.3
Davis, D.L.4
Gillette, J.R.5
Brodie, B.B.6
-
30
-
-
13844314221
-
The role of metabolic activation in drug-induced hepatotoxicity
-
Park, BK, Kitteringham NR, Maggs JL, Pirmohamed M, Williams RP. The role of metabolic activation in drug-induced hepatotoxicity. Annu Rev Pharmacol Toxicol 2005;45:177-202.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 177-202
-
-
Park, B.K.1
Kitteringham, N.R.2
Maggs, J.L.3
Pirmohamed, M.4
Williams, R.P.5
-
31
-
-
18844373318
-
Role of metabolism in drug-induced idiosyncratic hepatotoxicity
-
Walgren JL, Mitchell MD, Thompson DC. Role of metabolism in drug-induced idiosyncratic hepatotoxicity. Crit Rev Toxicol 2005;35:325-361.
-
(2005)
Crit Rev Toxicol
, vol.35
, pp. 325-361
-
-
Walgren, J.L.1
Mitchell, M.D.2
Thompson, D.C.3
-
32
-
-
1642281756
-
Drug-protein adducts: An industry perspective on minimizing the potential for drug bioactivation in drug discovery and development
-
Evans DC, Watt AP, Nicoll-Grifith DA, Baillie TA. Drug-protein adducts: an industry perspective on minimizing the potential for drug bioactivation in drug discovery and development. Chem Res Toxicol 2004;17:3-16.
-
(2004)
Chem Res Toxicol
, vol.17
, pp. 3-16
-
-
Evans, D.C.1
Watt, A.P.2
Nicoll-Grifith, D.A.3
Baillie, T.A.4
-
33
-
-
18944401259
-
Elucidating mechanisms of drug-induced toxicity
-
Liebler DC, Guengerich FP. Elucidating mechanisms of drug-induced toxicity. Nat Rev Drug Discov 2005;4:410-420.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 410-420
-
-
Liebler, D.C.1
Guengerich, F.P.2
-
34
-
-
85056690721
-
Mechanisms of acetaminophen-induced liver disease
-
Kaplowitz N, DeLeve LD, eds. New York: Marcel Dekker Inc.
-
Nelson SD. Mechanisms of acetaminophen-induced liver disease. In:. Kaplowitz N, DeLeve LD, eds. Drug-induced Liver Disease. New York: Marcel Dekker Inc., 2003:287-325.
-
(2003)
Drug-induced Liver Disease
, pp. 287-325
-
-
Nelson, S.D.1
-
35
-
-
0035197725
-
Interindividual variability in acetaminophen glucuronidation by human liver microsomes: Identification of relevant acetaminophen UDP- glucuronosyltransferase isoforms
-
Court MH, Duan SX, von Moltke LL, Greenblatt DJ, Patten CJ, Miners JO. Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms. J Pharmacol Exp Ther 2001;299:998-1006.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 998-1006
-
-
Court, M.H.1
Duan, S.X.2
Von Moltke, L.L.3
Greenblatt, D.J.4
Patten, C.J.5
Miners, J.O.6
-
36
-
-
0020310135
-
Platelet phenol sulfotransferase activity: Correlation with sulfate conjugation of acetaminophen
-
Reiter C, Weinshilboum R. Platelet phenol sulfotransferase activity: correlation with sulfate conjugation of acetaminophen. Clin Pharmacol Ther 1982;32:612-621.
-
(1982)
Clin Pharmacol Ther
, vol.32
, pp. 612-621
-
-
Reiter, C.1
Weinshilboum, R.2
-
37
-
-
7544222964
-
Coordinate regulation of drug metabolism by xenobiotic nuclear receptors: UGTs acting together with CYPs and glucuronide transporters
-
Bock KW, Kohle C. Coordinate regulation of drug metabolism by xenobiotic nuclear receptors: UGTs acting together with CYPs and glucuronide transporters. Drug Metab Rev 2004;36:595-615.
-
(2004)
Drug Metab Rev
, vol.36
, pp. 595-615
-
-
Bock, K.W.1
Kohle, C.2
-
38
-
-
0035836698
-
An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen
-
Chan K, Han XD, Kan YW. An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen. Proc Natl Acad Sci U S A 2001;98:4611-4616.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 4611-4616
-
-
Chan, K.1
Han, X.D.2
Kan, Y.W.3
-
39
-
-
0035153227
-
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
-
Enomoto A, Itoh K, Nagayoshi E, Haruta J, Kimura T, O'Connor T, et al. High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol Sci 2001;59:169-177.
-
(2001)
Toxicol Sci
, vol.59
, pp. 169-177
-
-
Enomoto, A.1
Itoh, K.2
Nagayoshi, E.3
Haruta, J.4
Kimura, T.5
O'Connor, T.6
-
40
-
-
0026545451
-
Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome
-
de Morais SM, Uetrecht JP, Wells PG. Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome. Gastroenterology 1992;102:577-586.
-
(1992)
Gastroenterology
, vol.102
, pp. 577-586
-
-
Morais, S.M.1
Uetrecht, J.P.2
Wells, P.G.3
-
41
-
-
0141563559
-
Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats
-
Luyendyk JP, Maddox JF, Cosma GN, Ganey PE, Cockerell GL, Roth RA. Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats. J Pharmacol Exp Ther 2003;307:9-16.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 9-16
-
-
Luyendyk, J.P.1
Maddox, J.F.2
Cosma, G.N.3
Ganey, P.E.4
Cockerell, G.L.5
Roth, R.A.6
-
42
-
-
7444233368
-
Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharideranitidine coexposure in rats
-
Luyendyk JP, Maddox JF, Green CD, Ganey PE, Roth RA. Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharideranitidine coexposure in rats. HEPATOLOGY 2004;40:1342-1351.
-
(2004)
Hepatology
, vol.40
, pp. 1342-1351
-
-
Luyendyk, J.P.1
Maddox, J.F.2
Green, C.D.3
Ganey, P.E.4
Roth, R.A.5
-
43
-
-
23944501121
-
Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharide and ranitidine
-
Luyendyk, JP, Shaw PJ, Green CD, Maddox JF, Ganey PE, Roth RA. Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharide and ranitidine. J Pharmacol Exp Ther 2005;314:1023-1031.
-
(2005)
J Pharmacol Exp Ther
, vol.314
, pp. 1023-1031
-
-
Luyendyk, J.P.1
Shaw, P.J.2
Green, C.D.3
Maddox, J.F.4
Ganey, P.E.5
Roth, R.A.6
-
44
-
-
3242777001
-
Gene expression analysis points to hemostasis in livers of rats cotreated with lipopolysaccharide and ranitidine
-
Luyendyk, JP, Mattes WB, Burgoon LD, Zacharewski TR, Maddox JF, Cosma GN, et al. Gene expression analysis points to hemostasis in livers of rats cotreated with lipopolysaccharide and ranitidine. Toxicol Sci 2004;80:203-213.
-
(2004)
Toxicol Sci
, vol.80
, pp. 203-213
-
-
Luyendyk, J.P.1
Mattes, W.B.2
Burgoon, L.D.3
Zacharewski, T.R.4
Maddox, J.F.5
Cosma, G.N.6
-
45
-
-
7444268462
-
Adverse hepatic drug reactions: Inflammatory episodes as consequence and contributor
-
Ganey, PE, Luyendyk JP, Maddox JF, Roth RA. Adverse hepatic drug reactions: inflammatory episodes as consequence and contributor. Chem Biol Interact 2004;150:35-51.
-
(2004)
Chem Biol Interact
, vol.150
, pp. 35-51
-
-
Ganey, P.E.1
Luyendyk, J.P.2
Maddox, J.F.3
Roth, R.A.4
-
46
-
-
20844444779
-
Idiosyncratic drug hepatotoxicity
-
Kaplowitz N. Idiosyncratic drug hepatotoxicity. Nat Rev Drug Discov 2005;4:489-499.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 489-499
-
-
Kaplowitz, N.1
-
47
-
-
9644289366
-
Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity
-
Liu ZX, Govindarajan S, Kaplowitz N. Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity. Gastroenterology 2004;127:1760-1774.
-
(2004)
Gastroenterology
, vol.127
, pp. 1760-1774
-
-
Liu, Z.X.1
Govindarajan, S.2
Kaplowitz, N.3
-
48
-
-
0036325858
-
A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury
-
Ishida, Y, Kondo T, Ohshima T, Fujiwara H, Iwakura Y, Mukaida N. A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury. FASEB J 2002;16:1227-1236.
-
(2002)
FASEB J
, vol.16
, pp. 1227-1236
-
-
Ishida, Y.1
Kondo, T.2
Ohshima, T.3
Fujiwara, H.4
Iwakura, Y.5
Mukaida, N.6
-
49
-
-
0033891369
-
Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis
-
Zhang, H, Cook J, Nickel J, Yu R, Stecker K, Myers K, et al. Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis. Nat Biotechnol 2000;18:862-867.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 862-867
-
-
Zhang, H.1
Cook, J.2
Nickel, J.3
Yu, R.4
Stecker, K.5
Myers, K.6
-
50
-
-
0036154452
-
Protection against acetaminophen-induced liver injury and lethality by interleukin 10: Role of inducible nitric oxide synthase
-
Bourdi, M, Masubuchi Y, Reilly TP, Amouzadeh HR, Martin JL, George JW, et al. Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase. HEPATOLOGY 2002;35:289-298.
-
(2002)
Hepatology
, vol.35
, pp. 289-298
-
-
Bourdi, M.1
Masubuchi, Y.2
Reilly, T.P.3
Amouzadeh, H.R.4
Martin, J.L.5
George, J.W.6
-
51
-
-
0345146918
-
Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease
-
Masubuchi, Y, Bourdi M, Reilly TP, Graf ML, George JW, Pohl LR. Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease. Biochem Biophys Res Commun 2003;304:207-212.
-
(2003)
Biochem Biophys Res Commun
, vol.304
, pp. 207-212
-
-
Masubuchi, Y.1
Bourdi, M.2
Reilly, T.P.3
Graf, M.L.4
George, J.W.5
Pohl, L.R.6
-
52
-
-
4243354763
-
The immunological mediation of drug reactions affecting the liver
-
Farrell GC, ed. Edinburgh, Scotland: Churchill Livingstone
-
Mackey I. The immunological mediation of drug reactions affecting the liver. In: Farrell GC, ed. Drug-induced Liver Disease. Edinburgh, Scotland: Churchill Livingstone, 1994:413-430.
-
(1994)
Drug-induced Liver Disease
, pp. 413-430
-
-
Mackey, I.1
-
53
-
-
16244420838
-
Autoimmune hepatitis induced by statins
-
Siddiqui J, Abraham J, Alla V, Chalasani NP, Wu Hy, Bonkovsky HL. Autoimmune hepatitis induced by statins. Gastroenterology 2005;(4 Suppl 2):A171.
-
(2005)
Gastroenterology
, Issue.4 SUPPL. 2
-
-
Siddiqui, J.1
Abraham, J.2
Alla, V.3
Chalasani, N.P.4
Wu, H.Y.5
Bonkovsky, H.L.6
-
54
-
-
0038240975
-
Drug-induced lupus-like syndrome associated with severe autoimmune hepatitis
-
Graziadei IW, Obermoser GE, Sepp NT, Erhart KH, Vogel W. Drug-induced lupus-like syndrome associated with severe autoimmune hepatitis. Lupus 2003;12:409-412.
-
(2003)
Lupus
, vol.12
, pp. 409-412
-
-
Graziadei, I.W.1
Obermoser, G.E.2
Sepp, N.T.3
Erhart, K.H.4
Vogel, W.5
-
55
-
-
0042315312
-
Autoimmune hepatitis revealed by atorvastatin
-
Pelli N, Setti M, Ceppa P, Toncini C, Indiveri F. Autoimmune hepatitis revealed by atorvastatin. Eur J Gastroenterol Hepatol 2003;15:921-924.
-
(2003)
Eur J Gastroenterol Hepatol
, vol.15
, pp. 921-924
-
-
Pelli, N.1
Setti, M.2
Ceppa, P.3
Toncini, C.4
Indiveri, F.5
-
56
-
-
17844410403
-
Rosuvastatin-associated hepatitis with autoimmune features
-
Wolters LM, Van Buuren HR. Rosuvastatin-associated hepatitis with autoimmune features. Eur J Gastroenterol Hepatol 2005;17:589-590.
-
(2005)
Eur J Gastroenterol Hepatol
, vol.17
, pp. 589-590
-
-
Wolters, L.M.1
Van Buuren, H.R.2
-
57
-
-
2542603322
-
Autoimmune hepatitis
-
Schiff ER, Maddrey WC, eds. Philadelphia, PA: Lippincott Williams & Wilkins
-
Kravitt EL, Autoimmune hepatitis. In: Schiff ER, Maddrey WC, eds. Schiffs Diseases of the Liver. Philadelphia, PA: Lippincott Williams & Wilkins, 2003:1001-1018.
-
(2003)
Schiffs Diseases of the Liver
, pp. 1001-1018
-
-
Kravitt, E.L.1
-
58
-
-
0032432444
-
Drug-induced immunotoxicity
-
Dansette PM, Bonierbale E, Minoletti C, Beaune PH, Pessayre D, Mansuy D. Drug-induced immunotoxicity. Eur J Drug Metab Pharmacokinet 1998;23:443-451.
-
(1998)
Eur J Drug Metab Pharmacokinet
, vol.23
, pp. 443-451
-
-
Dansette, P.M.1
Bonierbale, E.2
Minoletti, C.3
Beaune, P.H.4
Pessayre, D.5
Mansuy, D.6
-
60
-
-
0033171569
-
Drug- and chemical-induced cholestasis
-
Lewis JH, Zimmerman HJ. Drug- and chemical-induced cholestasis. Clin Liver Dis 1999;3:433-464, vii.
-
(1999)
Clin Liver Dis
, vol.3
, pp. 433-464
-
-
Lewis, J.H.1
Zimmerman, H.J.2
-
61
-
-
0030626785
-
Vanishing bile duct syndrome in drug-induced liver disease
-
Desmet VJ. Vanishing bile duct syndrome in drug-induced liver disease. J Hepatol 1997;26(Suppl 1):31-35.
-
(1997)
J Hepatol
, vol.26
, Issue.SUPPL. 1
, pp. 31-35
-
-
Desmet, V.J.1
-
62
-
-
0026585530
-
Drug-induced prolonged cholestasis in adults: A histological semiquantitative study demonstrating progressive ductopenia
-
Degott C, Feldmann G, Larrey D, Durand-Schneider AM, Grange D, Macheyokhi JT, et al. Drug-induced prolonged cholestasis in adults: a histological semiquantitative study demonstrating progressive ductopenia. HEPATOLOGY 1992;15:244-251.
-
(1992)
Hepatology
, vol.15
, pp. 244-251
-
-
Degott, C.1
Feldmann, G.2
Larrey, D.3
Durand-Schneider, A.M.4
Grange, D.5
Macheyokhi, J.T.6
-
64
-
-
0034382936
-
Molecular Mechanisms in Bile Formation
-
Meier PJ, Stieger B. Molecular Mechanisms in Bile Formation. News Physiol Sci 2000;15:89-93.
-
(2000)
News Physiol Sci
, vol.15
, pp. 89-93
-
-
Meier, P.J.1
Stieger, B.2
-
65
-
-
0036256463
-
Mechanisms of hepatic transport of drugs: Implications for cholestatic drug reactions
-
Bohan A, Boyer JL. Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions. Semin Liver Dis 2002;22:123-136.
-
(2002)
Semin Liver Dis
, vol.22
, pp. 123-136
-
-
Bohan, A.1
Boyer, J.L.2
-
66
-
-
0027320960
-
Inhibition by cyclosporin A of adenosine triphosphate-dependent transport from the hepatocyte into bile
-
Kadmon M, Klunemann, Bohme C, Ishikawa M, Gorgas T, Otto K, et al. Inhibition by cyclosporin A of adenosine triphosphate-dependent transport from the hepatocyte into bile. Gastroenterology 1993;104:1507-1514.
-
(1993)
Gastroenterology
, vol.104
, pp. 1507-1514
-
-
Kadmon, M.1
Klunemann2
Bohme, C.3
Ishikawa, M.4
Gorgas, T.5
Otto, K.6
-
67
-
-
0031746239
-
Selective protein adduct formation of diclofenac glucuronide is critically dependent on the rat canalicular conjugate export pump (Mrp2)
-
Seitz S, Kretz-Rommel A, Oude Elferink RP, Boelsterli UA. Selective protein adduct formation of diclofenac glucuronide is critically dependent on the rat canalicular conjugate export pump (Mrp2). Chem Res Toxicol 1998;11:513-519.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 513-519
-
-
Seitz, S.1
Kretz-Rommel, A.2
Oude Elferink, R.P.3
Boelsterli, U.A.4
-
68
-
-
0034234705
-
Mrp2 is essential for estradiol-17beta(beta-D-glucuronide)-induced cholestasis in rats
-
Huang L, Smit JW, Meijer DK, Vore M. Mrp2 is essential for estradiol-17beta(beta-D-glucuronide)-induced cholestasis in rats. HEPATOLOGY 2000;32:66-72.
-
(2000)
Hepatology
, vol.32
, pp. 66-72
-
-
Huang, L.1
Smit, J.W.2
Meijer, D.K.3
Vore, M.4
-
69
-
-
23044510006
-
Hepatic MRI for fat quantitation: Its relationship to fat morphology, diagnosis, and ultrasound
-
Fishbein M, Castro F, Cheruku S, Jain S, Webb B, Gleason T, et al. Hepatic MRI for fat quantitation: its relationship to fat morphology, diagnosis, and ultrasound. J Clin Gastroenterol 2005;39:619-625.
-
(2005)
J Clin Gastroenterol
, vol.39
, pp. 619-625
-
-
Fishbein, M.1
Castro, F.2
Cheruku, S.3
Jain, S.4
Webb, B.5
Gleason, T.6
-
70
-
-
0029127584
-
Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity
-
Fromenty B, Pessayre D. Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity. Pharmacol Ther 1995;67:101-154.
-
(1995)
Pharmacol Ther
, vol.67
, pp. 101-154
-
-
Fromenty, B.1
Pessayre, D.2
-
71
-
-
0038643426
-
Inhibition of microsomal triglyceride transfer protein: Another mechanism for drug-induced steatosis in mice
-
Letteron P, Sutton A, Mansouri A, Fromenty B, Pessayre D. Inhibition of microsomal triglyceride transfer protein: another mechanism for drug-induced steatosis in mice. HEPATOLOGY 2003;38:133-140.
-
(2003)
Hepatology
, vol.38
, pp. 133-140
-
-
Letteron, P.1
Sutton, A.2
Mansouri, A.3
Fromenty, B.4
Pessayre, D.5
-
72
-
-
0028990381
-
Mitochondrial toxicity of antiviral drugs
-
Lewis W, Dalakas MC. Mitochondrial toxicity of antiviral drugs. Nat Med 1995;1:417422.
-
(1995)
Nat Med
, vol.1
, pp. 417422
-
-
Lewis, W.1
Dalakas, M.C.2
-
73
-
-
0034913895
-
Acute ethanol administration oxidatively damages and depletes mitochondrial dna in mouse liver, brain, heart, and skeletal muscles: Protective effects of antioxidants
-
Mansouri A, Demeilliers C, Amsellem S, Pessayre D, Fromenty B. Acute ethanol administration oxidatively damages and depletes mitochondrial dna in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants. J Pharmacol Exp Ther 2001;298:737-743.
-
(2001)
J Pharmacol Exp Ther
, vol.298
, pp. 737-743
-
-
Mansouri, A.1
Demeilliers, C.2
Amsellem, S.3
Pessayre, D.4
Fromenty, B.5
-
74
-
-
0031921972
-
Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes
-
Berson A, De Beco V, Letteron P, Robin A, Moreau C, El Kahwaji J, et al. Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes. Gastroenterology 1998;114:764-774.
-
(1998)
Gastroenterology
, vol.114
, pp. 764-774
-
-
Berson, A.1
De Beco, V.2
Letteron, P.3
Robin, A.4
Moreau, C.5
El Kahwaji, J.6
-
75
-
-
0036125693
-
Toxic injury to hepatic sinusoids: Sinusoidal obstruction syndrome (veno-occlusive disease)
-
DeLeve LD, Shulman HM, McDonald GB. Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease). Semin Liver Dis 2002;22:27-42.
-
(2002)
Semin Liver Dis
, vol.22
, pp. 27-42
-
-
DeLeve, L.D.1
Shulman, H.M.2
McDonald, G.B.3
-
76
-
-
0034666010
-
Protein targets of monocrotaline pyrrole in pulmonary artery endothelial cells
-
Lamé MW, Jones AD, Wilson DW, Dunston SK, Segall HJ. Protein targets of monocrotaline pyrrole in pulmonary artery endothelial cells. J Biol Chem 2000;275:29091-29099.
-
(2000)
J Biol Chem
, vol.275
, pp. 29091-29099
-
-
Lamé, M.W.1
Jones, A.D.2
Wilson, D.W.3
Dunston, S.K.4
Segall, H.J.5
-
77
-
-
0042825692
-
Prevention of sinusoidal obstruction syndrome (hepatic venoocclusive disease) in the rat by matrix metalloproteinase inhibitors
-
DeLeve LD, Wang X, Tsai J, Kanel GC, Strasberg SM, Tokes ZA. Prevention of sinusoidal obstruction syndrome (hepatic venoocclusive disease) in the rat by matrix metalloproteinase inhibitors. Gastroenterology 2003;125:882-890.
-
(2003)
Gastroenterology
, vol.125
, pp. 882-890
-
-
DeLeve, L.D.1
Wang, X.2
Tsai, J.3
Kanel, G.C.4
Strasberg, S.M.5
Tokes, Z.A.6
-
78
-
-
0037908971
-
Embolization by sinusoidal lining cell obstructs the microcirculation in rat sinusoidal obstruction syndrome
-
DeLeve LD, Ito I, Bethea NW, McCuskey MK, Wang X, McCuskey RS. Embolization by sinusoidal lining cell obstructs the microcirculation in rat sinusoidal obstruction syndrome. Am J Physiol Gastro Liver Physiol 2003;284:G1045-G1052.
-
(2003)
Am J Physiol Gastro Liver Physiol
, vol.284
-
-
DeLeve, L.D.1
Ito, I.2
Bethea, N.W.3
McCuskey, M.K.4
Wang, X.5
McCuskey, R.S.6
-
79
-
-
0033995653
-
Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells
-
Eberhardt W, Beeg T, Beck KF, Walpen S, Gauer S, Bohles H, et al. Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells. Kidney Int 2000;57:59-69.
-
(2000)
Kidney Int
, vol.57
, pp. 59-69
-
-
Eberhardt, W.1
Beeg, T.2
Beck, K.F.3
Walpen, S.4
Gauer, S.5
Bohles, H.6
-
80
-
-
0035406154
-
Nitric oxide inhibition increases matrix metalloproteinase-9 expression by rat aortic smooth muscle cells in vitro
-
Upchurch GR Jr, Ford JW, Weiss SJ, Knipp BS, Peterson DA, Thompson RW, et al. Nitric oxide inhibition increases matrix metalloproteinase-9 expression by rat aortic smooth muscle cells in vitro. J Vasc Surg 2001;34:76-83.
-
(2001)
J Vasc Surg
, vol.34
, pp. 76-83
-
-
Upchurch Jr., G.R.1
Ford, J.W.2
Weiss, S.J.3
Knipp, B.S.4
Peterson, D.A.5
Thompson, R.W.6
-
81
-
-
0141532294
-
Decreased hepatic nitric oxide production contributes to the development of rat sinusoidal obstruction syndrome
-
DeLeve LD, Wang X, Kanel GC, Ito Y, Bethea NW, McCuskey MK, et al. Decreased hepatic nitric oxide production contributes to the development of rat sinusoidal obstruction syndrome. HEPATOLOGY 2003;38:900-908.
-
(2003)
Hepatology
, vol.38
, pp. 900-908
-
-
DeLeve, L.D.1
Wang, X.2
Kanel, G.C.3
Ito, Y.4
Bethea, N.W.5
McCuskey, M.K.6
-
82
-
-
0028316959
-
Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease
-
Watkins PB, Zimmerman HJ, Knapp MJ, Gracon SI, Lewis KW. Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease. JAMA 1994;271:992-998.
-
(1994)
JAMA
, vol.271
, pp. 992-998
-
-
Watkins, P.B.1
Zimmerman, H.J.2
Knapp, M.J.3
Gracon, S.I.4
Lewis, K.W.5
-
83
-
-
0035199230
-
Nephrotoxicity and hepatotoxicity induced by inhaled bromodichloromethane in wild-type and p53-heterozygous mice
-
Torti VR, CobbA J, Everitt JI, Marshall MW, Boorman GA, Butterworth BE. Nephrotoxicity and hepatotoxicity induced by inhaled bromodichloromethane in wild-type and p53-heterozygous mice. Toxicol Sci 2001;64:269-280.
-
(2001)
Toxicol Sci
, vol.64
, pp. 269-280
-
-
Torti, V.R.1
Cobba, J.2
Everitt, J.I.3
Marshall, M.W.4
Boorman, G.A.5
Butterworth, B.E.6
-
84
-
-
0033058105
-
Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: An explanation for high acetaminophen dosage in humans without hepatic injury
-
Shayiq RM, Roberts DW, Rothstein K, Snawder JE, Benson W, Ma X, et al. Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: an explanation for high acetaminophen dosage in humans without hepatic injury. HEPATOLOGY 1999;29:451-463.
-
(1999)
Hepatology
, vol.29
, pp. 451-463
-
-
Shayiq, R.M.1
Roberts, D.W.2
Rothstein, K.3
Snawder, J.E.4
Benson, W.5
Ma, X.6
-
85
-
-
12344322514
-
Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride
-
Aleksunes LM, Slitt AM, Cherrington NJ, Thibodeau MS, Klaassen CD, Manautou JE. Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride. Toxicol Sci 2005;83:44-52.
-
(2005)
Toxicol Sci
, vol.83
, pp. 44-52
-
-
Aleksunes, L.M.1
Slitt, A.M.2
Cherrington, N.J.3
Thibodeau, M.S.4
Klaassen, C.D.5
Manautou, J.E.6
-
86
-
-
4143070233
-
Interleukin-6 regulates hepatic transporters during acute-phase response
-
Siewert E, Dietrich CG, Lammert F, Heinrich PC, Matern S, Gartung C, et al. Interleukin-6 regulates hepatic transporters during acute-phase response. Biochem Biophys Res Commun 2004;322:232-238.
-
(2004)
Biochem Biophys Res Commun
, vol.322
, pp. 232-238
-
-
Siewert, E.1
Dietrich, C.G.2
Lammert, F.3
Heinrich, P.C.4
Matern, S.5
Gartung, C.6
-
87
-
-
0020694356
-
Resistance to hepatotoxins acquired by hepatocytes during liver regeneration
-
Roberts E, Ahluwalia MB, Lee G, Chan C, Sarma DS, Farber E, et al. Resistance to hepatotoxins acquired by hepatocytes during liver regeneration. Cancer Res 1983;43:28-34.
-
(1983)
Cancer Res
, vol.43
, pp. 28-34
-
-
Roberts, E.1
Ahluwalia, M.B.2
Lee, G.3
Chan, C.4
Sarma, D.S.5
Farber, E.6
-
88
-
-
12544259261
-
Hepatotoxicity of antiretrovirals: Incidence, mechanisms and management
-
Nunez M, Soriano V. Hepatotoxicity of antiretrovirals: incidence, mechanisms and management. Drug Saf 2005;28:53-66.
-
(2005)
Drug Saf
, vol.28
, pp. 53-66
-
-
Nunez, M.1
Soriano, V.2
-
90
-
-
0037342098
-
Severe hepatotoxicity during combination antiretroviral treatment: Incidence, liver histology, and outcome
-
Puoti M, Torti C, Ripamonti D, Castelli F, Zaltron S, Zanini B, et al. Severe hepatotoxicity during combination antiretroviral treatment: incidence, liver histology, and outcome. J Acquir Immune Defic Syndr 2003;32:259-267.
-
(2003)
J Acquir Immune Defic Syndr
, vol.32
, pp. 259-267
-
-
Puoti, M.1
Torti, C.2
Ripamonti, D.3
Castelli, F.4
Zaltron, S.5
Zanini, B.6
-
91
-
-
0242363266
-
Mitochondrial toxicity of NRTI antiviral drugs: An integrated cellular perspective
-
Lewis W, Day BJ, Copeland WC. Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective. Nat Rev Drug Discov 2003;2:812-822.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 812-822
-
-
Lewis, W.1
Day, B.J.2
Copeland, W.C.3
-
92
-
-
3242879742
-
Metabonomics: Systems biology in pharmaceutical research and development
-
Lindon JC, Holmes E, Nicholson JK. Metabonomics: systems biology in pharmaceutical research and development. Curr Opin Mol Ther 2004;6:265-272.
-
(2004)
Curr Opin Mol Ther
, vol.6
, pp. 265-272
-
-
Lindon, J.C.1
Holmes, E.2
Nicholson, J.K.3
-
93
-
-
1542268299
-
Metabonomics and its role in drug development and disease diagnosis
-
Lindon JC, Holmes E, Nicholson JK. Metabonomics and its role in drug development and disease diagnosis. Expert Rev Mol Diagn 2004;4:189-199.
-
(2004)
Expert Rev Mol Diagn
, vol.4
, pp. 189-199
-
-
Lindon, J.C.1
Holmes, E.2
Nicholson, J.K.3
-
94
-
-
0036463681
-
Metabonomics: A platform for studying drug toxicity and gene function
-
Nicholson JK, Nicholson JK, Connelly J, Lindon JC, Holmes E. Metabonomics: a platform for studying drug toxicity and gene function. Nat Rev Drug Discov 2002;1:153-1561.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 153-1561
-
-
Nicholson, J.K.1
Nicholson, J.K.2
Connelly, J.3
Lindon, J.C.4
Holmes, E.5
-
95
-
-
26944489574
-
The Consortium for Metabonomic Toxicology (COMET): Aims, activities and achievements
-
Lindon JC, Keun HC, Ebbels TM, Pearce JM, Holmes E, Nicholson JK. The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements. Pharmacogenomics 2005;6:691-699.
-
(2005)
Pharmacogenomics
, vol.6
, pp. 691-699
-
-
Lindon, J.C.1
Keun, H.C.2
Ebbels, T.M.3
Pearce, J.M.4
Holmes, E.5
Nicholson, J.K.6
-
96
-
-
0345714918
-
NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats
-
Nicholls AW, Mortishire-Smith RJ, Nicholson JK. NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats. Chem Res Toxicol 2003;16:1395-1404.
-
(2003)
Chem Res Toxicol
, vol.16
, pp. 1395-1404
-
-
Nicholls, A.W.1
Mortishire-Smith, R.J.2
Nicholson, J.K.3
-
97
-
-
17844404232
-
Gut microorganisms, mammalian metabolism and personalized health care
-
Nicholson JK, Holmes E, Wilson ID. Gut microorganisms, mammalian metabolism and personalized health care. Nat Rev Microbiol 2005;3:431-438.
-
(2005)
Nat Rev Microbiol
, vol.3
, pp. 431-438
-
-
Nicholson, J.K.1
Holmes, E.2
Wilson, I.D.3
-
98
-
-
17844370543
-
Advances in knowledge management for pharmaceutical research and development
-
Torr-Brown S. Advances in knowledge management for pharmaceutical research and development. Curr Opin Drug Discov Devel 2005;8:316-322.
-
(2005)
Curr Opin Drug Discov Devel
, vol.8
, pp. 316-322
-
-
Torr-Brown, S.1
-
100
-
-
0030865914
-
Development and validation of a clinical scale for the diagnosis of drug-induced hepatitis
-
Maria VA, Victorino RM. Development and validation of a clinical scale for the diagnosis of drug-induced hepatitis. HEPATOLOGY 1997;26:664-669.
-
(1997)
Hepatology
, vol.26
, pp. 664-669
-
-
Maria, V.A.1
Victorino, R.M.2
-
101
-
-
0035200244
-
Comparison of two clinical scales for causality assessment in hepatotoxicity
-
Lucena MI, Camargo R, Andrade RJ, Perez-Sanchez CJ, Sanchez De La Cuesta F. Comparison of two clinical scales for causality assessment in hepatotoxicity. HEPATOLOGY 2001;33:123-130.
-
(2001)
Hepatology
, vol.33
, pp. 123-130
-
-
Lucena, M.I.1
Camargo, R.2
Andrade, R.J.3
Perez-Sanchez, C.J.4
Sanchez De La Cuesta, F.5
-
102
-
-
0033661511
-
Clinical diagnostic scale: A useful tool in the evaluation of suspected hepatotoxic adverse drug reactions
-
Aithal GP, Rawlins MD, Day CP. Clinical diagnostic scale: a useful tool in the evaluation of suspected hepatotoxic adverse drug reactions. J Hepatol 2000;33:949-952.
-
(2000)
J Hepatol
, vol.33
, pp. 949-952
-
-
Aithal, G.P.1
Rawlins, M.D.2
Day, C.P.3
-
103
-
-
0038669335
-
Causality assessment of adverse drug reactions: Comparison of the results obtained from published decisional algorithms and from the evaluations of an expert panel, according to different levels of imputability
-
Macedo AF, Marques FB, Ribeiro CF, Teixeira F. Causality assessment of adverse drug reactions: comparison of the results obtained from published decisional algorithms and from the evaluations of an expert panel, according to different levels of imputability. J Clin Pharm Ther 2003;28:137-143.
-
(2003)
J Clin Pharm Ther
, vol.28
, pp. 137-143
-
-
Macedo, A.F.1
Marques, F.B.2
Ribeiro, C.F.3
Teixeira, F.4
-
104
-
-
0035986526
-
Drug hepatotoxicity
-
Goodman ZD. Drug hepatotoxicity. Clin Liver Dis 2002;6:381-397.
-
(2002)
Clin Liver Dis
, vol.6
, pp. 381-397
-
-
Goodman, Z.D.1
-
106
-
-
0030997076
-
Histopathologic changes associated with fialuridine hepatotoxicity
-
Kleiner DE, Gaffey MJ, Sallie R, Tsokos M, Nichols L, McKenzie R, et al. Histopathologic changes associated with fialuridine hepatotoxicity. Mod Pathol 1997;10:192-199.
-
(1997)
Mod Pathol
, vol.10
, pp. 192-199
-
-
Kleiner, D.E.1
Gaffey, M.J.2
Sallie, R.3
Tsokos, M.4
Nichols, L.5
McKenzie, R.6
-
107
-
-
3242742968
-
Gene expression profiling of rat livers reveals indicators of potential adverse effects
-
Heinloth AN, Irwin RD, Boorman GA, Nettesheim P, Fannin RD, Sieber S, et al. Gene expression profiling of rat livers reveals indicators of potential adverse effects. Toxicol Sci 2004;80:193-202.
-
(2004)
Toxicol Sci
, vol.80
, pp. 193-202
-
-
Heinloth, A.N.1
Irwin, R.D.2
Boorman, G.A.3
Nettesheim, P.4
Fannin, R.D.5
Sieber, S.6
-
108
-
-
19644386887
-
Assessment of hepatotoxic liabilities by transcript profiling
-
Ruepp S, Boess F, Suter L, de Vera MC, Steiner G, Steele T, et al. Albertini, S. Assessment of hepatotoxic liabilities by transcript profiling. Toxicol Appl Pharmacol 2005;207(2 Suppl):161-170.
-
(2005)
Toxicol Appl Pharmacol
, vol.207
, Issue.2 SUPPL.
, pp. 161-170
-
-
Ruepp, S.1
Boess, F.2
Suter, L.3
De Vera, M.C.4
Steiner, G.5
Steele, T.6
Albertini, S.7
-
109
-
-
0032618539
-
Drug metabolizing enzymes in lymphocytes
-
Raucy JL, Ingelman-Sundberg M, Carpenter S, Rannug A, Rane A, Franklin M, et al. Drug metabolizing enzymes in lymphocytes. J Biochem Mol Toxicol 1999;13:223-226.
-
(1999)
J Biochem Mol Toxicol
, vol.13
, pp. 223-226
-
-
Raucy, J.L.1
Ingelman-Sundberg, M.2
Carpenter, S.3
Rannug, A.4
Rane, A.5
Franklin, M.6
|