Involvement of miRNAs in the early phase of halothane-induced liver injury

Toxicology

Volumn 319, Issue 1, 2014, Pages 75-84

  Endo, Shinya ^a   Yano, Azusa ^a   Fukami, Tatsuki ^a   Nakajima, Miki ^a   Yokoi, Tsuyoshi ^a,b  

^a KANAZAWA UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Drug induced liver injury; Halothane; MiR 106b; MiRNA; STAT3

Indexed keywords

HALOTHANE; ISOFLURANE; MICRORNA; MICRORNA 101A; MICRORNA 106B; MICRORNA 125B 5P; MICRORNA 126 3P; MICRORNA 126 5P; MICRORNA 145; MICRORNA 148A; MICRORNA 148B; MICRORNA 152; MICRORNA 15A; MICRORNA 17; MICRORNA 200A; MICRORNA 200C; MICRORNA 20B; MICRORNA 21; MICRORNA 24; MICRORNA 27A; MICRORNA 27B; MICRORNA 295; MICRORNA 29B; MICRORNA 30A; MICRORNA 30D; MICRORNA 31; MICRORNA 497; MICRORNA 93; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; FEMALE; GENE TARGETING; IMMUNE SYSTEM; INFLAMMATION; LIVER INJURY; LIVER TOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOXIC HEPATITIS; UPREGULATION;

DRUG-INDUCED LIVER INJURY; HALOTHANE; MIR-106B; MIRNA; STAT3;

ALANINE TRANSAMINASE; ANIMALS; CYTOKINES; DRUG-INDUCED LIVER INJURY; FEMALE; HALOTHANE; LIVER; MICE; MICE, INBRED BALB C; MICRORNAS; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR;

EID: 84897835125     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.02.011     Document Type: Article

References (46)

1. Bourdi M., Amouzadeh H.R., Rushmore T.H., Martin J.L., Pohl L.R. Halothane-induced liver injury in outbred guinea pigs: role of trifluoracetylated protein adducts in animal susceptibility. Chem. Res. Toxicol. 2001, 14:362-370.
2. Bi Y., Liu G., Yang R. MicroRNAs: novel regulators during the immune response. J. Cell Physiol. 2009, 218:467-472.
3. Carraro G., El-Hashash A., Guidolin D., Tiozzo C., Turcatel G., Young B.M., De_Langhe S.P., Bellusci S., Shi W., Parnigotto P.P., Warburton D. miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev. Biol. 2009, 333:238-250.
4. Chenand S., Xuan J., Guo L. microRNAs in drug-induced liver toxicity. microRNAs in Toxicology and Medicine 2013, 33-47.
5. Cheng L., You Q., Yin H., Holt M.P., Ju C. Involvement of natural killer T cells in halothane-induced liver injury in mice. Biochem. Phamacol. 2010, 80:255-261.
6. Friedman R.C., Farh K.K., Burge C.B., Bartel D.P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009, 19:92-105.
7. Fukushima T., Hamada Y., Yamada H., Horii I. Changes of micro-RNA expression in rat liver treated by acetaminophen or carbon tetrachloride, regulation role of micro-RNA for RNA expression. J. Toxicol. Sci. 2007, 32:401-409.
8. Gut J., Christen U., Huwyler J. Mechanisms of halothane toxicity: novel insights. Pharmacol. Ther. 1993, 58:133-155.
9. Higuchi S., Kobayashi M., Yano A., Tsuneyama K., Fukami T., Nakajima M., Yokoi T. Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury. J. Appl. Toxicol. 2012, 32:815-822.
10. Higuchi S., Kobayashi M., Yoshikawa Y., Tsuneyama K., Fukami T., Nakajima M., Yokoi T. IL-4 mediates dicloxacillin-induced liver injury in mice. Toxicol. Lett. 2011, 200:139-145.
11. Higuchi S., Yano A., Takai S., Tsuneyama K., Fukami T., Nakajima M., Yokoi T. Metabolic activation and inflammation reactions involved in carbamazepine-induced liver injury. Toxicol. Sci 2012, 130:4-16.
12. Hou L., Wang D., Baccarelli A. Environmental chemicals and microRNAs. Mutat. Res. 2011, 714:105-112.
13. Hsu S.D., Lin F.M., Wu W.Y., Liang C., Huang W.C., Chan W.L., Tsai W.T., Chen G.Z., Lee C.J., Chiu C.M., Chien C.H., Wu M.C., Huang C.Y., Tsou A.P., Huang H.D. miRTarBase: a database curates experimentally validated microRNA-target interactions. Nucleic Acids Res. 2011, 39:D163-D169.
14. Ivanov I.I., Zhou L., Littman D.R. Transcriptional regulation of Th17 cell differentiation. Semin. Immunol. 2007, 19:409-417.
15. Kanehisa M. The KEGG database. Novartis Found Symp. 2002, 247:91-101.
16. Kanehisa M., Goto S., Hattori M., Aoki-Kinoshita K.F., Itoh M., Kawashima S., Katayama T., Araki M., Hirakawa M. From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res. 2006, 34:D354-D357.
17. Kobayashi E., Kobayashi M., Tsuneyama K., Fukami T., Nakajima M., Yokoi T. Halothane-induced liver injury is mediated by interleukin-17 in mice. Toxicol. Sci. 2009, 111:302-310.
18. Komagata S., Nakajima M., Takagi S., Mohri T., Taniya T., Yokoi T. Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b. Mol. Pharmacol. 2009, 76:702-709.
19. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
20. Latronico M.V., Catalucci D., Condorelli G. MicroRNA and cardiac pathologies. Physiol. Genom. 2008, 34:239-242.
21. Lee Y.S., Dutta A. MicroRNAs in Cancer. Annu. Rev. Pathol. Mech. Dis. 2009, 4:199-227.
22. Lema C., Cunningham M.J. MicroRNAs and their implications in toxicological research. Toxicol. Lett. 2010, 198:100-105.
23. Mohri T., Nakajima M., Fukami T., Takamiya M., Aoki Y., Yokoi T. Human CYP2E1 is regulated by miR-378. Biochem. Pharmacol. 2010, 79:1045-1052.
24. Nelson K.M., Weiss G.J. MicroRNAs and cancer: past, present, and potential future. Mol. Cancer. Ther. 2008, 7:3655-3660.
25. Njoku D., Laster M.J., Gong D.H., Eger E.I., Reed G.F., Martin J.L. Biotransformation of halothane, enflurane, isoflurane, and desflurane to trifluoroacetylated liver proteins: association between protein acylation and hepatic injury. Anesth. Analg. 1997, 84:173-178.
26. O'Connell R.M., Rao D.S., Chaudhuri A.A., Baltimore D. Physiological and pathological roles for microRNAs in the immune system. Nat. Rev. Immunol. 2010, 10:111-122.
27. Pillai R.S. MicroRNA function: multiple mechanisms for a tiny RNA?. RNA 2005, 11:1753-1761.
28. Pogribny I.P., Tryndyak V.P., Boyko A., Rodriguez-Juarez R., Beland F.A., Kovalchuk O. Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure. Mutat. Res. 2007, 619:30-37.
29. Ray D.C., Drummond G.B. Halothane hepatitis. Br. J. Anaesth. 1991, 67:84-99.
30. Roderburg C., Urban G.W., Bettermann K., Vucur M., Zimmermann H., Schmidt S., Janssen J., Koppe C., Knolle P., Castoldi M., Tacke F., Trautwein C., Luedde T. Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis. Hepatology 2011, 53:209-218.
31. Sasaki E., Matsuo K., Iida A., Tsuneyama K., Fukami T., Nakajima M., Yokoi T. A novel mouse model for phenytoin-induced liver injury: involvement of immune-related factors and P450-mediated metabolism. Toxicol. Sci. 2013, 136:250-263.
32. Surdziel E., Cabanski M., Dallmann I., Lyszkiewicz M., Krueger A., Ganser A., Scherr M., Eder M. Enforced expression of miR-125b affects myelopoiesis by targeting multiple signaling pathways. Blood 2011, 117:4338-4348.
33. Takamizawa J., Konishi H., Yanagisawa K., Tomida S., Osada H., Endoh H., Harano T., Yatabe Y., Nagino M., Nimura Y., Mitsudomi T., Takahashi T. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 2004, 64:3753-3756.
34. Tan G., Niu J., Shi Y., Ouyang H., Wu Z.H. NF-κB-dependent microRNA-125b up-regulation promotes cell survival by targeting p38α upon ultraviolet radiation. J. Biol. Chem. 2012, 287:33036-33047.
35. Toyoda Y., Endo S., Tsuneyama K., Miyashita T., Yano A., Fukami T., Nakajima M., Yokoi T. Mechanism of exacerbative effect of progesterone on drug-induced liver injury. Toxicol. Sci. 2011, 126:16-27.
36. Tsuchiya Y., Nakajima M., Takagi S., Taniya T., Yokoi T. MicroRNA regulates the expression of human cytochrome P450 1B1. Cancer Res. 2006, 66:9090-9098.
37. Vlachos I.S., Kostoulas N., Vergoulis T., Georgakilas G., Reczko M., Maragkakis M., Paraskevopoulou M.D., Prionidis K., Dalamagas T., Hatzigeorgiou A.G. DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic Acids Res. 2012, 40:W498-W504.
38. Wang K., Zhang S., Marzolf B., Troisch P., Brightman A., Hu Z., Hood L.E., Galas D.J. Circulating miRNAs, potential biomarkers for drug-induced liver injury. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:4402-4407.
39. Wei L., Laurence A., Elias K.M., O'Shea J.J. IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J. Biol. Chem. 2007, 282:34605-34610.
40. Wu F., Zikusoka M., Trindade A., Dassopoulos T., Harris M.L., Bayless T.M., Brant S.R., Chakravarti S., Kwon J.H. MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha. Gastroenterology 2008, 135:1624-1635.
41. Yang X.O., Panopoulos A.D., Nurieva R., Chang S.H., Wang D., Watowich S.S., Dong C. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J. Biol. Chem. 2007, 282:9358-9363.
42. Yano A., Higuchi S., Tsuneyama K., Fukami T., Nakajima M., Yokoi T. Involvement of immune-related factors in diclofenac-induced acute liver injury in mice. Toxicology 2012, 293:107-114.
43. Yokoi T., Nakajima M. microRNAs as mediators of drug toxicity. Ann. Rev. Pharmacol. Toxicol. 2013, 53:377-400.
44. You Q., Cheng L., Reilly T.P., Wegmann D., Ju C. Role of neutrophils in a mouse model of halothane-induced liver injury. Hepatology 2006, 44:1421-1431.
45. Zamore P.D., Haley B. Ribo-gnome: the big world of small RNAs. Science 2005, 309:1519-1524.
46. Zhu J., Paul W.E. CD4T cells: fates, functions, and faults. Blood 2008, 112:1557-1569.