A gene expression signature for oxidant stress/reactive metabolites in rat liver

Biochemical Pharmacology

Volumn 68, Issue 11, 2004, Pages 2249-2261

  McMillian, Michael ^a   Nie, Alex Y ^a   Parker, J Brandon ^a   Leone, Angelique ^a   Bryant, Stewart ^a   Kemmerer, Michael ^a   Herlich, Judy ^a   Liu, Yanhong ^a   Yieh, Lynn ^a   Bittner, Anton ^a   Liu, Xuejun ^a   Wan, Jackson ^a   Johnson, Mark D ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Free radicals; Microarray; Nrf 2; Oxidative stress; Reactive metabolites

Indexed keywords

16ALPHA CYANOPREGNENOLONE; 4 METHYLTHIAZOLE; ANETHOLE; ANILINE; BROMOBENZENE; BUTYLCRESOL; CONCANAVALIN A; DIELDRIN; DISULFIRAM; ERYTHROMYCIN ESTOLATE; ETHINYLESTRADIOL; FLUFENAMIC ACID; FLUOXETINE; FLUTAMIDE; GADOLINIUM CHLORIDE; LINDANE; METOPROLOL; N (2 FLUORENYL)ACETAMIDE; NIMESULIDE; PHENACETIN; PIPERONYL BUTOXIDE; PIRINIXIC ACID; PRECOCENE I; PULEGONE; SULINDAC; TANNIN; THIAZOLE DERIVATIVE; TROGLITAZONE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DATA BASE; DNA MICROARRAY; DRUG ACTIVITY; DRUG MECHANISM; DRUG MEGADOSE; GENE EXPRESSION; LIVER; LIVER TOXICITY; MACROPHAGE ACTIVATION; MALE; METABOLITE; MULTIVARIATE ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PREDICTION; PRIORITY JOURNAL; RAT;

ANIMALS; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; LIVER; MACROPHAGE-ACTIVATING FACTORS; NF-E2-RELATED FACTOR 2; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PEROXISOME PROLIFERATORS; RATS; RATS, SPRAGUE-DAWLEY; TRANS-ACTIVATORS;

EID: 7444231518     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.08.003     Document Type: Article

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