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Volumn 7, Issue 2, 2013, Pages 307-315

Hopes and challenges in using miRNAs as translational biomarkers for drug-induced liver injury

Author keywords

acetaminophen; biomarker; DILI; drug induced liver injury; hepatotoxicity; miRNA

Indexed keywords

ALCOHOL; BIOLOGICAL MARKER; CARBON TETRACHLORIDE; DOXORUBICIN; METHAPYRILENE; MICRORNA; MICRORNA 122; MICRORNA 22; PARACETAMOL; PARAQUAT; PENICILLIN DERIVATIVE; PHENOBARBITAL;

EID: 84875826688     PISSN: 17520363     EISSN: 17520371     Source Type: Journal    
DOI: 10.2217/bmm.13.9     Document Type: Review
Times cited : (22)

References (47)
  • 1
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta- analysis of prospective studies
    • DOI 10.1001/jama.279.15.1200
    • Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279(15), 1200-1205 (1998). (Pubitemid 28193431)
    • (1998) Journal of the American Medical Association , vol.279 , Issue.15 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 2
    • 0033661511 scopus 로고    scopus 로고
    • Clinical diagnostic scale: A useful tool in the evaluation of suspected hepatotoxic adverse drug reactions
    • Aithal GP, Rawlins MD, Day CP. Clinical diagnostic scale: a useful tool in the evaluation of suspected hepatotoxic adverse drug reactions. J. Hepatol. 33(6), 949-952 (2000).
    • (2000) J. Hepatol. , vol.33 , Issue.6 , pp. 949-952
    • Aithal, G.P.1    Rawlins, M.D.2    Day, C.P.3
  • 4
    • 34250344637 scopus 로고    scopus 로고
    • A prospective study of acute drug-induced liver injury in patients suffering from non-alcoholic fatty liver disease
    • DOI 10.1111/j.1872-034X.2007.00072.x
    • Tarantino G, Conca P, Basile V et al. A prospective study of acute drug-induced liver injury in patients suffering from non-alcoholic fatty liver disease. Hepatol. Res. 37(6), 410-415 (2007). (Pubitemid 46915785)
    • (2007) Hepatology Research , vol.37 , Issue.6 , pp. 410-415
    • Tarantino, G.1    Conca, P.2    Basile, V.3    Gentile, A.4    Capone, D.5    Polichetti, G.6    Leo, E.7
  • 8
    • 84872142803 scopus 로고    scopus 로고
    • Exploring microRNA biomarkers for disease monitoring and response to therapy
    • Tung J. Exploring microRNA biomarkers for disease monitoring and response to therapy. Bioanalysis 4(18), 2204 (2012).
    • (2012) Bioanalysis , vol.4 , Issue.18 , pp. 2204
    • Tung, J.1
  • 10
    • 63149121152 scopus 로고    scopus 로고
    • Circulating microRNAs, potential biomarkers for drug-induced liver injury
    • Wang K, Zhang S, Marzolf B et al. Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc. Natl Acad. Sci. USA 106(11), 4402-4407 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.11 , pp. 4402-4407
    • Wang, K.1    Zhang, S.2    Marzolf, B.3
  • 11
    • 84865404634 scopus 로고    scopus 로고
    • Serum microRNA biomarkers for drug-induced liver injury
    • Starkey Lewis PJ, Merz M, Couttet P et al. Serum microRNA biomarkers for drug-induced liver injury. Clin. Pharmacol. Ther. 92(3), 291-293 (2012).
    • (2012) Clin. Pharmacol. Ther. , vol.92 , Issue.3 , pp. 291-293
    • Starkey Lewis, P.J.1    Merz, M.2    Couttet, P.3
  • 12
    • 80055038826 scopus 로고    scopus 로고
    • Circulating microRNAs as potential markers of human drug-induced liver injury
    • Starkey Lewis PJ, Dear J, Platt V et al. Circulating microRNAs as potential markers of human drug-induced liver injury. Hepatology 54(5), 1767-1776 (2011).
    • (2011) Hepatology , vol.54 , Issue.5 , pp. 1767-1776
    • Starkey Lewis, P.J.1    Dear, J.2    Platt, V.3
  • 13
    • 84868211262 scopus 로고    scopus 로고
    • Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases
    • Bala S, Petrasek J, Mundkur S et al. Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. Hepatology 56(5), 1946-1957 (2012).
    • (2012) Hepatology , vol.56 , Issue.5 , pp. 1946-1957
    • Bala, S.1    Petrasek, J.2    Mundkur, S.3
  • 14
    • 84862070687 scopus 로고    scopus 로고
    • A panel of serum microRNAs as specific biomarkers for diagnosis of compound-and herb-induced liver injury in rats
    • Su YW, Chen X, Jiang ZZ et al. A panel of serum microRNAs as specific biomarkers for diagnosis of compound-and herb-induced liver injury in rats. PLoS ONE 7(5), e37395 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.5
    • Su, Y.W.1    Chen, X.2    Jiang, Z.Z.3
  • 15
    • 84855892790 scopus 로고    scopus 로고
    • Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity
    • Jaeschke H, Mcgill MR, Ramachandran A. Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity. Drug Metab. Rev. 44(1), 88-106 (2012).
    • (2012) Drug Metab. Rev. , vol.44 , Issue.1 , pp. 88-106
    • Jaeschke, H.1    McGill, M.R.2    Ramachandran, A.3
  • 17
    • 84863087125 scopus 로고    scopus 로고
    • Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: A research study
    • Ward J, Bala S, Petrasek J, Szabo G. Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: a research study. World J. Gastroenterol. 18(22), 2798-2804 (2012).
    • (2012) VWorld J. Gastroenterol. , vol.18 , Issue.22 , pp. 2798-2804
    • Ward, J.1    Bala, S.2    Petrasek, J.3    Szabo, G.4
  • 18
    • 84875846434 scopus 로고    scopus 로고
    • Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats
    • doi:10.1177/0192623312464436 Epub ahead of print
    • Starckx S, Batheja A, Verheyen GR et al. Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats. Toxicol. Pathol. doi:10.1177/0192623312464436 (2012) (Epub ahead of print).
    • (2012) Toxicol. Pathol.
    • Starckx, S.1    Batheja, A.2    Verheyen, G.R.3
  • 19
    • 84857166172 scopus 로고    scopus 로고
    • Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis
    • Yamaura Y, Nakajima M, Takagi S, Fukami T, Tsuneyama K, Yokoi T. Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis. PLoS ONE 7(2), e30250 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.2
    • Yamaura, Y.1    Nakajima, M.2    Takagi, S.3    Fukami, T.4    Tsuneyama, K.5    Yokoi, T.6
  • 21
    • 78649837734 scopus 로고    scopus 로고
    • Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases
    • Zhang Y, Jia Y, Zheng R et al. Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases. Clin. Chem. 56(12), 1830-1838 (2010).
    • (2010) Clin. Chem. , vol.56 , Issue.12 , pp. 1830-1838
    • Zhang, Y.1    Jia, Y.2    Zheng, R.3
  • 22
    • 84870576402 scopus 로고    scopus 로고
    • Review article: Herbal and dietary supplement hepatotoxicity
    • Bunchorntavakul C, Reddy KR. Review article: herbal and dietary supplement hepatotoxicity. Aliment. Pharmacol. Ther. 37(1), 3-17 (2013).
    • (2013) Aliment. Pharmacol. Ther. , vol.37 , Issue.1 , pp. 3-17
    • Bunchorntavakul, C.1    Reddy, K.R.2
  • 23
    • 67651250138 scopus 로고    scopus 로고
    • Drug-induced liver injury due to "natural products" used for weight loss: A case report
    • Tarantino G, Pezzullo MG, Di Minno MN et al. Drug-induced liver injury due to "natural products" used for weight loss: a case report. World J. Gastroenterol. 15(19), 2414-2417 (2009).
    • (2009) World J. Gastroenterol. , vol.15 , Issue.19 , pp. 2414-2417
    • Tarantino, G.1    Pezzullo, M.G.2    Di Minno, M.N.3
  • 24
    • 84860744644 scopus 로고    scopus 로고
    • Circulating microRNA-122 as a potential biomarker for liver injury
    • Ding X, Ding J, Ning J et al. Circulating microRNA-122 as a potential biomarker for liver injury. Mol. Med. Report 5(6), 1428-1432 (2012).
    • (2012) Mol. Med. Report , vol.5 , Issue.6 , pp. 1428-1432
    • Ding, X.1    Ding, J.2    Ning, J.3
  • 25
    • 84867811724 scopus 로고    scopus 로고
    • Cell-free microRNAs in urine as diagnostic and prognostic biomarkers of bladder cancer
    • Yun SJ, Jeong P, Kim WT et al. Cell-free microRNAs in urine as diagnostic and prognostic biomarkers of bladder cancer. Int. J. Oncol. 41(5), 1871-1878 (2012).
    • (2012) Int. J. Oncol. , vol.41 , Issue.5 , pp. 1871-1878
    • Yun, S.J.1    Jeong, P.2    Kim, W.T.3
  • 26
    • 84862019046 scopus 로고    scopus 로고
    • Circulating and urinary microRNAs in kidney disease
    • Lorenzen JM, Thum T. Circulating and urinary microRNAs in kidney disease. Clin. J. Am. Soc. Nephrol. 7(9), 1528-1533 (2012).
    • (2012) Clin. J. Am. Soc. Nephrol. , vol.7 , Issue.9 , pp. 1528-1533
    • Lorenzen, J.M.1    Thum, T.2
  • 27
    • 84862954550 scopus 로고    scopus 로고
    • Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity
    • Yang X, Greenhaw J, Shi Q et al. Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity. Toxicol. Sci. 125(2), 335-344 (2012).
    • (2012) Toxicol. Sci. , vol.125 , Issue.2 , pp. 335-344
    • Yang, X.1    Greenhaw, J.2    Shi, Q.3
  • 28
    • 78649752499 scopus 로고    scopus 로고
    • Regulation and biological function of the liver-specific miR-122
    • Lewis AP, Jopling CL. Regulation and biological function of the liver-specific miR-122. Biochem. Soc. Trans. 38(6), 1553-1557 (2010).
    • (2010) Biochem. Soc. Trans. , vol.38 , Issue.6 , pp. 1553-1557
    • Lewis, A.P.1    Jopling, C.L.2
  • 29
    • 84869120708 scopus 로고    scopus 로고
    • Discovering the first microRNA-targeted drug
    • Lindow M, Kauppinen S. Discovering the first microRNA-targeted drug. J. Cell. Biol. 199(3), 407-412 (2012).
    • (2012) J. Cell. Biol. , vol.199 , Issue.3 , pp. 407-412
    • Lindow, M.1    Kauppinen, S.2
  • 30
    • 70449709341 scopus 로고    scopus 로고
    • Plasma microRNAs as sensitive and specific biomarkers of tissue injury
    • Laterza OF, Lim L, Garrett-Engele PW et al. Plasma microRNAs as sensitive and specific biomarkers of tissue injury. Clin. Chem. 55(11), 1977-1983 (2009).
    • (2009) Clin. Chem. , vol.55 , Issue.11 , pp. 1977-1983
    • Laterza, O.F.1    Lim, L.2    Garrett-Engele, P.W.3
  • 32
    • 75949123612 scopus 로고    scopus 로고
    • Blood gene expression markers to detect and distinguish target organ toxicity
    • Umbright C, Sellamuthu R, Li S, Kashon M, Luster M, Joseph P. Blood gene expression markers to detect and distinguish target organ toxicity. Mol. Cell. Biochem. 335(1-2), 223-234 (2010).
    • (2010) Mol. Cell. Biochem. , vol.335 , Issue.1-2 , pp. 223-234
    • Umbright, C.1    Sellamuthu, R.2    Li, S.3    Kashon, M.4    Luster, M.5    Joseph, P.6
  • 33
    • 84858081410 scopus 로고    scopus 로고
    • Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans
    • Jetten MJ, Gaj S, Ruiz-Aracama A et al. 'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans. Toxicol. Appl. Pharmacol. 259(3), 320-328 (2012).
    • (2012) Toxicol. Appl. Pharmacol. , vol.259 , Issue.3 , pp. 320-328
    • Jetten, M.J.1    Gaj, S.2    Ruiz-Aracama, A.3
  • 34
    • 84865063456 scopus 로고    scopus 로고
    • Classification of the four main types of lung cancer using a microRNA-based diagnostic assay
    • Gilad S, Lithwick-Yanai G, Barshack I et al. Classification of the four main types of lung cancer using a microRNA-based diagnostic assay. J. Mol. Diagn. 14(5), 510-517 (2012).
    • (2012) J. Mol. Diagn. , vol.14 , Issue.5 , pp. 510-517
    • Gilad, S.1    Lithwick-Yanai, G.2    Barshack, I.3
  • 35
    • 84860858416 scopus 로고    scopus 로고
    • Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials
    • Vlassov AV, Magdaleno S, Setterquist R, Conrad R. Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials. Biochim. Biophys. Acta 1820(7), 940-948 (2012).
    • (2012) Biochim. Biophys. Acta , vol.7 , pp. 940-948
    • Vlassov, A.V.1    Magdaleno, S.2    Setterquist, R.3    Conrad, R.4
  • 36
    • 84858195484 scopus 로고    scopus 로고
    • Liver-specific microRNA-122: Biogenesis and function
    • Jopling C. Liver-specific microRNA-122: biogenesis and function. RNA Biol. 9(2), 137-142 (2012).
    • (2012) RNA Biol. , vol.9 , Issue.2 , pp. 137-142
    • Jopling, C.1
  • 37
    • 84868618214 scopus 로고    scopus 로고
    • Current challenges and controversies in drug-induced liver injury
    • Corsini A, Ganey P, Ju C et al. Current challenges and controversies in drug-induced liver injury. Drug Saf. 35(12), 1099-1117 (2012).
    • (2012) Drug Saf. , vol.35 , Issue.12 , pp. 1099-1117
    • Corsini, A.1    Ganey, P.2    Ju, C.3
  • 38
    • 13444273562 scopus 로고    scopus 로고
    • Recognizing drug-induced liver injury: Current problems, possible solutions
    • DOI 10.1080/01926230590522356
    • Lee WM, Senior Jr. Recognizing drug-induced liver injury: current problems, possible solutions. Toxicol. Pathol. 33(1), 155-164 (2005). (Pubitemid 40216814)
    • (2005) Toxicologic Pathology , vol.33 , Issue.1 , pp. 155-164
    • Lee, W.M.1    Senior, J.R.2
  • 39
    • 67651244726 scopus 로고    scopus 로고
    • Drug-induced liver injury: Is it somehow foreseeable?
    • Tarantino G, Di Minno MN, Capone D. Drug-induced liver injury: is it somehow foreseeable? World J. Gastroenterol. 15(23), 2817-2833 (2009).
    • (2009) World J. Gastroenterol. , vol.15 , Issue.23 , pp. 2817-2833
    • Tarantino, G.1    Di Minno, M.N.2    Capone, D.3
  • 40
    • 84859464569 scopus 로고    scopus 로고
    • Blood cell origin of circulating microRNAs: A cautionary note for cancer biomarker studies
    • Pritchard CC, Kroh E, Wood B et al. Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies. Cancer Prev. Res. (Phila.) 5(3), 492-497 (2012).
    • (2012) Cancer Prev. Res. (Phila.) , vol.5 , Issue.3 , pp. 492-497
    • Pritchard, C.C.1    Kroh, E.2    Wood, B.3
  • 41
    • 84859931528 scopus 로고    scopus 로고
    • Identification of endogenous normalizers for serum microRNAs by microarray profiling: U6 small nuclear RNA is not a reliable normalizer
    • author reply 1642-1643
    • Qi R, Weiland M, Gao XH, Zhou L, Mi QS. Identification of endogenous normalizers for serum microRNAs by microarray profiling: U6 small nuclear RNA is not a reliable normalizer. Hepatology 55(5), 1640-1642; author reply 1642-1643 (2012).
    • (2012) Hepatology , vol.55 , Issue.5 , pp. 1640-1642
    • Qi, R.1    Weiland, M.2    Gao, X.H.3    Zhou, L.4    Mi, Q.S.5
  • 42
    • 84871205828 scopus 로고    scopus 로고
    • Reference genes for real-time PCR quantification of microRNAs and messenger RNAs in rat models of hepatotoxicity
    • Lardizabal MN, Nocito AL, Daniele SM, Ornella LA, Palatnik JF, Veggi LM. Reference genes for real-time PCR quantification of microRNAs and messenger RNAs in rat models of hepatotoxicity. PLoS ONE 7(5), e36323 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.5
    • Lardizabal, M.N.1    Nocito, A.L.2    Daniele, S.M.3    Ornella, L.A.4    Palatnik, J.F.5    Veggi, L.M.6
  • 43
    • 48649088515 scopus 로고    scopus 로고
    • PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes
    • Thulin P, Rafter I, Stockling K et al. PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes. Toxicol. Appl. Pharmacol. 231(1), 1-9 (2008).
    • (2008) Toxicol. Appl. Pharmacol. , vol.231 , Issue.1 , pp. 1-9
    • Thulin, P.1    Rafter, I.2    Stockling, K.3
  • 44
    • 77956470019 scopus 로고    scopus 로고
    • Translational medicine and the value of biomarker qualification
    • Goodsaid FM, Mendrick DL. Translational medicine and the value of biomarker qualification. Sci. Transl Med. 2(47), 47ps44 (2010).
    • (2010) Sci. Transl Med. , vol.2 , Issue.47
    • Goodsaid, F.M.1    Mendrick, D.L.2
  • 45
    • 79959236929 scopus 로고    scopus 로고
    • Impact of cellular miRNAs on circulating miRNA biomarker signatures
    • Duttagupta R, Jiang R, Gollub J, Getts RC, Jones KW. Impact of cellular miRNAs on circulating miRNA biomarker signatures. PLoS One 6(6), e20769 (2011).
    • (2011) PLoS One , vol.6 , Issue.6
    • Duttagupta, R.1    Jiang, R.2    Gollub, J.3    Getts, R.C.4    Jones, K.W.5
  • 46
    • 77952702755 scopus 로고    scopus 로고
    • Causality assessment in drug-induced liver injury using a structured expert opinion process: Comparison to the Roussel-Uclaf causality assessment method
    • Rockey DC, Seeff LB, Rochon J et al. Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method. Hepatology 51(6), 2117-2126 (2010).
    • (2010) Hepatology , vol.51 , Issue.6 , pp. 2117-2126
    • Rockey, D.C.1    Seeff, L.B.2    Rochon, J.3
  • 47
    • 84860389774 scopus 로고    scopus 로고
    • Causality assessment methods in drug induced liver injury: Strengths and weaknesses
    • Garcia-Cortes M, Stephens C, Lucena Mi, Fernandez-Castaner A, Andrade RJ. Causality assessment methods in drug induced liver injury: strengths and weaknesses. J. Hepatol. 55(3), 683-691 (2011).
    • (2011) J. Hepatol. , vol.55 , Issue.3 , pp. 683-691
    • Garcia-Cortes, M.1    Stephens, C.2    Mi, L.3    Fernandez-Castaner, A.4    Andrade, R.J.5


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