SLCO1B1*15 haplotype is associated with rifampin-induced liver injury

Molecular Medicine Reports

Volumn 6, Issue 1, 2012, Pages 75-82

  Li, Ling Min ^a   Chen, Lei ^a   Deng, Guo Hong ^a   Tan, Wen Ting ^a   Dan, Yun Jie ^a   Wang, Rong Quan ^a   Chen, Wen Sheng ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Haplotype; Organic anion transporting polypeptide 1B1; Pharmacogenetics; Polymorphism; Rifampin induced liver injury

Indexed keywords

BILE ACID; ORGANIC ANION TRANSPORTER 2; RIFAMPICIN; ORGANIC ANION TRANSPORTER; SLCO1B1 PROTEIN, HUMAN; TUBERCULOSTATIC AGENT;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CHINESE; CHOLESTASIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA POLYMORPHISM; DRUG INDUCED DISEASE; FEMALE; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HUMAN; LIVER INJURY; LIVER TOXICITY; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; POPULATION GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE; CASE CONTROL STUDY; CELL STRAIN HEK293; GENE EXPRESSION; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; METABOLISM; MIDDLE AGED; TOXIC HEPATITIS;

ADULT; ANTIBIOTICS, ANTITUBERCULAR; CASE-CONTROL STUDIES; DRUG-INDUCED LIVER INJURY; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HEK293 CELLS; HUMANS; MALE; MIDDLE AGED; ORGANIC ANION TRANSPORTERS; POLYMORPHISM, SINGLE NUCLEOTIDE; RIFAMPIN; YOUNG ADULT;

EID: 84861607709     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.900     Document Type: Article

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