-
1
-
-
79959213923
-
Drug-induced liver injury: a summary of recent advances
-
Stine JG, Lewis JH, (2011) Drug-induced liver injury: a summary of recent advances. ExpertOpinDrug Metab Toxicol 7: 875-890.
-
(2011)
ExpertOpinDrug Metab Toxicol
, vol.7
, pp. 875-890
-
-
Stine, J.G.1
Lewis, J.H.2
-
2
-
-
39649094514
-
The current state of serum biomakers of hepatotoxicity
-
Ozer J, Ratner M, Shaw M, Bailey W, Schomaker S, (2008) The current state of serum biomakers of hepatotoxicity. Toxicology 245: 194-205.
-
(2008)
Toxicology
, vol.245
, pp. 194-205
-
-
Ozer, J.1
Ratner, M.2
Shaw, M.3
Bailey, W.4
Schomaker, S.5
-
3
-
-
56149105113
-
Using controlled clinical trials to learn more about acute drug-induced liver injury
-
Watkins PB, Seligman PJ, Pears JS, Avigan MI, Senior JR, (2008) Using controlled clinical trials to learn more about acute drug-induced liver injury. Hepatology 48: 1680-1689.
-
(2008)
Hepatology
, vol.48
, pp. 1680-1689
-
-
Watkins, P.B.1
Seligman, P.J.2
Pears, J.S.3
Avigan, M.I.4
Senior, J.R.5
-
4
-
-
0029090947
-
Diclofenac-associated hepatotoxicity: analysis of 180 cases reported to the Food and Drug Administration as adverse reactions
-
Banks AT, Zimmerman HJ, Ishak KG, Harter JG, (1995) Diclofenac-associated hepatotoxicity: analysis of 180 cases reported to the Food and Drug Administration as adverse reactions. Hepatology 22: 820-827.
-
(1995)
Hepatology
, vol.22
, pp. 820-827
-
-
Banks, A.T.1
Zimmerman, H.J.2
Ishak, K.G.3
Harter, J.G.4
-
5
-
-
76649094231
-
Risk and management of liver toxicity during methotrexate treatment in rheumatoid and psoriatic arthritis: a systematic review of the literature
-
Visser K, van der Heijde DM, (2009) Risk and management of liver toxicity during methotrexate treatment in rheumatoid and psoriatic arthritis: a systematic review of the literature. Clin Exp Rheumatol 27: 1017-1025.
-
(2009)
Clin Exp Rheumatol
, vol.27
, pp. 1017-1025
-
-
Visser, K.1
van der Heijde, D.M.2
-
6
-
-
58849132807
-
The future of drug safety testing: expanding the view and narrowing the focus
-
Stevens JL, Baker TK, (2009) The future of drug safety testing: expanding the view and narrowing the focus. Drug DiscovToday 14: 162-167.
-
(2009)
Drug DiscovToday
, vol.14
, pp. 162-167
-
-
Stevens, J.L.1
Baker, T.K.2
-
7
-
-
79951999068
-
Challenges and opportunities for discovery of disease biomarkers using urine proteomics
-
Kentsis A, (2011) Challenges and opportunities for discovery of disease biomarkers using urine proteomics. PediatrInt 53: 1-6.
-
(2011)
PediatrInt
, vol.53
, pp. 1-6
-
-
Kentsis, A.1
-
8
-
-
79958236852
-
A Comprehensive Map of the Human Urinary Proteome
-
Marimuthu A, OMeally RN, Chaerkady R, Subbannayya Y, Nanjappa V, et al. (2011) A Comprehensive Map of the Human Urinary Proteome. JProteomeRes 10: 2734-2743.
-
(2011)
JProteomeRes
, vol.10
, pp. 2734-2743
-
-
Marimuthu, A.1
OMeally, R.N.2
Chaerkady, R.3
Subbannayya, Y.4
Nanjappa, V.5
-
9
-
-
34548185943
-
Urine profiling by SELDI-TOF/MS: monitoring of the critical steps in sample collection, handling and analysis
-
Papale M, Pedicillo MC, Thatcher BJ, Di PS, Lo ML, et al. (2007) Urine profiling by SELDI-TOF/MS: monitoring of the critical steps in sample collection, handling and analysis. J ChromatogrB AnalytTechnolBiomedLife Sci 856: 205-213.
-
(2007)
J ChromatogrB AnalytTechnolBiomedLife Sci
, vol.856
, pp. 205-213
-
-
Papale, M.1
Pedicillo, M.C.2
Thatcher, B.J.3
Di, P.S.4
Lo, M.L.5
-
10
-
-
79953692673
-
Mechanisms of drug-induced liver injury: from bedside to bench
-
Tujios S, Fontana RJ, (2011) Mechanisms of drug-induced liver injury: from bedside to bench. NatRevGastroenterolHepatol 8: 202-211.
-
(2011)
NatRevGastroenterolHepatol
, vol.8
, pp. 202-211
-
-
Tujios, S.1
Fontana, R.J.2
-
12
-
-
79954615800
-
Current issues with acetaminophen hepatotoxicity-A clinically relevant model to test the efficacy of natural products
-
Jaeschke H, McGill MR, Williams CD, Ramachandran A, (2011) Current issues with acetaminophen hepatotoxicity-A clinically relevant model to test the efficacy of natural products. Life Sci 88: 737-745.
-
(2011)
Life Sci
, vol.88
, pp. 737-745
-
-
Jaeschke, H.1
McGill, M.R.2
Williams, C.D.3
Ramachandran, A.4
-
13
-
-
33745945069
-
Alterations in the rat serum proteome during liver injury from acetaminophen exposure
-
Merrick BA, Bruno ME, Madenspacher JH, Wetmore BA, Foley J, et al. (2006) Alterations in the rat serum proteome during liver injury from acetaminophen exposure. JPharmacolExpTher 318: 792-802.
-
(2006)
JPharmacolExpTher
, vol.318
, pp. 792-802
-
-
Merrick, B.A.1
Bruno, M.E.2
Madenspacher, J.H.3
Wetmore, B.A.4
Foley, J.5
-
14
-
-
34548626321
-
Evaluation of human hepatocyte chimeric mice as a model for toxicological investigation using panomic approaches-effect of acetaminophen on the expression profiles of proteins and endogenous metabolites in liver, plasma and urine
-
Yamamoto T, Tomizawa K, Fujikawa M, Sato Y, Yamada H, et al. (2007) Evaluation of human hepatocyte chimeric mice as a model for toxicological investigation using panomic approaches-effect of acetaminophen on the expression profiles of proteins and endogenous metabolites in liver, plasma and urine. JToxicolSci 32: 205-215.
-
(2007)
JToxicolSci
, vol.32
, pp. 205-215
-
-
Yamamoto, T.1
Tomizawa, K.2
Fujikawa, M.3
Sato, Y.4
Yamada, H.5
-
15
-
-
0033920278
-
Two-dimensional database of mouse liver proteins: changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol
-
Fountoulakis M, Berndt P, Boelsterli UA, Crameri F, Winter M, et al. (2000) Two-dimensional database of mouse liver proteins: changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol. Electrophoresis 21: 2148-2161.
-
(2000)
Electrophoresis
, vol.21
, pp. 2148-2161
-
-
Fountoulakis, M.1
Berndt, P.2
Boelsterli, U.A.3
Crameri, F.4
Winter, M.5
-
16
-
-
36048980620
-
Biomarker discovery with SELDI-TOF MS in human urine associated with early renal injury: evaluation with computational analytical tools
-
Vanhoutte KJ, Laarakkers C, Marchiori E, Pickkers P, Wetzels JF, et al. (2007) Biomarker discovery with SELDI-TOF MS in human urine associated with early renal injury: evaluation with computational analytical tools. NephrolDialTransplant 22: 2932-2943.
-
(2007)
NephrolDialTransplant
, vol.22
, pp. 2932-2943
-
-
Vanhoutte, K.J.1
Laarakkers, C.2
Marchiori, E.3
Pickkers, P.4
Wetzels, J.F.5
-
17
-
-
33947396353
-
Standardized peptidome profiling of human urine by magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
-
Fiedler GM, Baumann S, Leichtle A, Oltmann A, Kase J, et al. (2007) Standardized peptidome profiling of human urine by magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Clin Chem 53: 421-428.
-
(2007)
Clin Chem
, vol.53
, pp. 421-428
-
-
Fiedler, G.M.1
Baumann, S.2
Leichtle, A.3
Oltmann, A.4
Kase, J.5
-
18
-
-
84855719955
-
Surface-affinity Profiling to Identify Host-Pathogen Interactions
-
Boleij A, Laarakkers CM, Gloerich J, Swinkels DW, Tjalsma H, (2011) Surface-affinity Profiling to Identify Host-Pathogen Interactions. InfectImmun 79: 4777-4783.
-
(2011)
InfectImmun
, vol.79
, pp. 4777-4783
-
-
Boleij, A.1
Laarakkers, C.M.2
Gloerich, J.3
Swinkels, D.W.4
Tjalsma, H.5
-
19
-
-
78650930806
-
Liquid chromatography-mass spectrometry-based proteomics of Nitrosomonas
-
Wessels HJ, Gloerich J, van der Biezen E, Jetten MS, Kartal B, (2011) Liquid chromatography-mass spectrometry-based proteomics of Nitrosomonas. Methods Enzymol 486: 465-482.
-
(2011)
Methods Enzymol
, vol.486
, pp. 465-482
-
-
Wessels, H.J.1
Gloerich, J.2
van der Biezen, E.3
Jetten, M.S.4
Kartal, B.5
-
20
-
-
79960358181
-
The molecular mechanisms of calmodulin action on TRPV5 and the modulation by parathyroid hormone
-
de Groot T, Kovalevskaya NV, Verkaart S, Schilderink N, Felici M, et al. (2011) The molecular mechanisms of calmodulin action on TRPV5 and the modulation by parathyroid hormone. MolCell Biol 31: 2845-2853.
-
(2011)
MolCell Biol
, vol.31
, pp. 2845-2853
-
-
de Groot, T.1
Kovalevskaya, N.V.2
Verkaart, S.3
Schilderink, N.4
Felici, M.5
-
21
-
-
0032489044
-
Paracetamol hepatotoxicity in metallothionein-null mice
-
Rofe AM, Barry EF, Shelton TL, Philcox JC, Coyle P, (1998) Paracetamol hepatotoxicity in metallothionein-null mice. Toxicology 125: 131-140.
-
(1998)
Toxicology
, vol.125
, pp. 131-140
-
-
Rofe, A.M.1
Barry, E.F.2
Shelton, T.L.3
Philcox, J.C.4
Coyle, P.5
-
22
-
-
70349317188
-
Dose response and time course studies on superoxide dismutase as a urinary biomarker of carbon tetrachloride-induced hepatic injury in the Hanover Wistar rat
-
Smyth R, Munday MR, York MJ, Clarke CJ, Dare T, et al. (2009) Dose response and time course studies on superoxide dismutase as a urinary biomarker of carbon tetrachloride-induced hepatic injury in the Hanover Wistar rat. IntJExpPathol 90: 500-511.
-
(2009)
IntJExpPathol
, vol.90
, pp. 500-511
-
-
Smyth, R.1
Munday, M.R.2
York, M.J.3
Clarke, C.J.4
Dare, T.5
-
23
-
-
47549119495
-
Urinary proteomics: towards biomarker discovery, diagnostics and prognostics
-
Thongboonkerd V, (2008) Urinary proteomics: towards biomarker discovery, diagnostics and prognostics. MolBiosyst 4: 810-815.
-
(2008)
MolBiosyst
, vol.4
, pp. 810-815
-
-
Thongboonkerd, V.1
-
24
-
-
0016514757
-
Acetaminophen poisoning and toxicity
-
Rumack BH, Matthew H, (1975) Acetaminophen poisoning and toxicity. Pediatrics 55: 871-876.
-
(1975)
Pediatrics
, vol.55
, pp. 871-876
-
-
Rumack, B.H.1
Matthew, H.2
-
25
-
-
52749093875
-
The interplay between nitric oxide and peroxiredoxins
-
Abbas K, Breton J, Drapier JC, (2008) The interplay between nitric oxide and peroxiredoxins. Immunobiology 213: 815-822.
-
(2008)
Immunobiology
, vol.213
, pp. 815-822
-
-
Abbas, K.1
Breton, J.2
Drapier, J.C.3
-
26
-
-
70349952323
-
Over-expression of Senescence Marker Protein-30 decreases reactive oxygen species in human hepatic carcinoma Hep G2 cells
-
Handa S, Maruyama N, Ishigami A, (2009) Over-expression of Senescence Marker Protein-30 decreases reactive oxygen species in human hepatic carcinoma Hep G2 cells. BiolPharmBull 32: 1645-1648.
-
(2009)
BiolPharmBull
, vol.32
, pp. 1645-1648
-
-
Handa, S.1
Maruyama, N.2
Ishigami, A.3
-
27
-
-
57349104966
-
D-Dopachrome tautomerase is a candidate for key proteins to protect the rat liver damaged by carbon tetrachloride
-
Hiyoshi M, Konishi H, Uemura H, Matsuzaki H, Tsukamoto H, et al. (2009) D-Dopachrome tautomerase is a candidate for key proteins to protect the rat liver damaged by carbon tetrachloride. Toxicology 255: 6-14.
-
(2009)
Toxicology
, vol.255
, pp. 6-14
-
-
Hiyoshi, M.1
Konishi, H.2
Uemura, H.3
Matsuzaki, H.4
Tsukamoto, H.5
-
28
-
-
0345003848
-
Carbonic anhydrase III protects cells from hydrogen peroxide-induced apoptosis
-
Raisanen SR, Lehenkari P, Tasanen M, Rahkila P, Harkonen PL, et al. (1999) Carbonic anhydrase III protects cells from hydrogen peroxide-induced apoptosis. FASEB J 13: 513-522.
-
(1999)
FASEB J
, vol.13
, pp. 513-522
-
-
Raisanen, S.R.1
Lehenkari, P.2
Tasanen, M.3
Rahkila, P.4
Harkonen, P.L.5
-
29
-
-
84055219018
-
Acetaminophen-induced hepatotoxicity and protein nitration in neuronal nitric-oxide synthase knockout mice
-
Agarwal R, Hennings L, Rafferty TM, Letzig LG, McCullough S, et al. (2012) Acetaminophen-induced hepatotoxicity and protein nitration in neuronal nitric-oxide synthase knockout mice. J Pharmacol Exp Ther 340: 134-142.
-
(2012)
J Pharmacol Exp Ther
, vol.340
, pp. 134-142
-
-
Agarwal, R.1
Hennings, L.2
Rafferty, T.M.3
Letzig, L.G.4
McCullough, S.5
-
30
-
-
79952007967
-
The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity
-
Ramachandran A, Lebofsky M, Weinman SA, Jaeschke H, (2011) The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity. Toxicol Appl Pharmacol 251: 226-233.
-
(2011)
Toxicol Appl Pharmacol
, vol.251
, pp. 226-233
-
-
Ramachandran, A.1
Lebofsky, M.2
Weinman, S.A.3
Jaeschke, H.4
-
31
-
-
70350202531
-
Role of cytochrome P450 2E1 in protein nitration and ubiquitin-mediated degradation during acetaminophen toxicity
-
Abdelmegeed MA, Moon KH, Chen C, Gonzalez FJ, Song BJ, (2010) Role of cytochrome P450 2E1 in protein nitration and ubiquitin-mediated degradation during acetaminophen toxicity. Biochem Pharmacol 79: 57-66.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 57-66
-
-
Abdelmegeed, M.A.1
Moon, K.H.2
Chen, C.3
Gonzalez, F.J.4
Song, B.J.5
-
32
-
-
0025605747
-
Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen-induced liver injury
-
Ray SD, Sorge CL, Raucy JL, Corcoran GB, (1990) Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen-induced liver injury. ToxicolApplPharmacol 106: 346-351.
-
(1990)
ToxicolApplPharmacol
, vol.106
, pp. 346-351
-
-
Ray, S.D.1
Sorge, C.L.2
Raucy, J.L.3
Corcoran, G.B.4
-
33
-
-
33646176751
-
Is there a specific role for the plasma membrane Ca2+ -ATPase in the hepatocyte?
-
Delgado-Coello B, Trejo R, Mas-Oliva J, (2006) Is there a specific role for the plasma membrane Ca2+-ATPase in the hepatocyte? MolCell Biochem 285: 1-15.
-
(2006)
MolCell Biochem
, vol.285
, pp. 1-15
-
-
Delgado-Coello, B.1
Trejo, R.2
Mas-Oliva, J.3
-
34
-
-
12844257477
-
Redox modulation of cellular signaling and metabolism through reversible oxidation of methionine sensors in calcium regulatory proteins
-
Bigelow DJ, Squier TC, (2005) Redox modulation of cellular signaling and metabolism through reversible oxidation of methionine sensors in calcium regulatory proteins. BiochimBiophysActa 1703: 121-134.
-
(2005)
BiochimBiophysActa
, vol.1703
, pp. 121-134
-
-
Bigelow, D.J.1
Squier, T.C.2
-
35
-
-
0024345539
-
Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3′-hydroxyacetanilide, in mouse liver
-
Tirmenstein MA, Nelson SD, (1989) Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3′-hydroxyacetanilide, in mouse liver. JBiolChem 264: 9814-9819.
-
(1989)
JBiolChem
, vol.264
, pp. 9814-9819
-
-
Tirmenstein, M.A.1
Nelson, S.D.2
-
36
-
-
0024487619
-
ATP stimulates Ca2+ uptake and increases the free Ca2+ concentration in isolated rat liver nuclei
-
Nicotera P, McConkey DJ, Jones DP, Orrenius S, (1989) ATP stimulates Ca2+ uptake and increases the free Ca2+ concentration in isolated rat liver nuclei. ProcNatlAcadSciUSA 86: 453-457.
-
(1989)
ProcNatlAcadSciUSA
, vol.86
, pp. 453-457
-
-
Nicotera, P.1
McConkey, D.J.2
Jones, D.P.3
Orrenius, S.4
|