-
2
-
-
79957773993
-
The inflammasomes in kidney disease
-
Anders HJ, Muruve DA. The inflammasomes in kidney disease. J Am Soc Nephrol 2011; 22: 1007-1018.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1007-1018
-
-
Anders, H.J.1
Muruve, D.A.2
-
3
-
-
84911992879
-
Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens
-
Knodler LA, Crowley SM, Sham HP, Yang H, Wrande M, Ma C, et al. Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens. Cell Host Microbe 2014; 16: 249-256.
-
(2014)
Cell Host Microbe
, vol.16
, pp. 249-256
-
-
Knodler, L.A.1
Crowley, S.M.2
Sham, H.P.3
Yang, H.4
Wrande, M.5
Ma, C.6
-
4
-
-
84882280029
-
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
-
Sagulenko V, Thygesen SJ, Sester DP, Idris A, Cridland JA, Vajjhala PR, et al. AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC. Cell Death Differ 2013; 20: 1149-1160.
-
(2013)
Cell Death Differ
, vol.20
, pp. 1149-1160
-
-
Sagulenko, V.1
Thygesen, S.J.2
Sester, D.P.3
Idris, A.4
Cridland, J.A.5
Vajjhala, P.R.6
-
5
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, et al. Non-canonical inflammasome activation targets caspase-11. Nature 2011; 479: 117-121.
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
-
6
-
-
79952708318
-
Caspase-8 and bid: Caught in the act between death receptors and mitochondria
-
Kantari C, Walczak H. Caspase-8 and bid: caught in the act between death receptors and mitochondria. Biochim Biophys Acta 2011; 1813: 558-563.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 558-563
-
-
Kantari, C.1
Walczak, H.2
-
7
-
-
69249208481
-
XIAP discriminates between type i and type II FAS-induced apoptosis
-
Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, et al. XIAP discriminates between type I and type II FAS-induced apoptosis. Nature 2009; 460: 1035-1039.
-
(2009)
Nature
, vol.460
, pp. 1035-1039
-
-
Jost, P.J.1
Grabow, S.2
Gray, D.3
McKenzie, M.D.4
Nachbur, U.5
Huang, D.C.6
-
8
-
-
0033529534
-
Differential modulation of apoptosis sensitivity in CD95 type i and type II cells
-
Scaffidi C, Schmitz I, Zha J, Korsmeyer SJ, Krammer PH, Peter ME. Differential modulation of apoptosis sensitivity in CD95 type I and type II cells. J Biol Chem 1999; 274: 22532-22538.
-
(1999)
J Biol Chem
, vol.274
, pp. 22532-22538
-
-
Scaffidi, C.1
Schmitz, I.2
Zha, J.3
Korsmeyer, S.J.4
Krammer, P.H.5
Peter, M.E.6
-
9
-
-
58149201240
-
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
-
Gonzalvez F, Schug ZT, Houtkooper RH, MacKenzie ED, Brooks DG, Wanders RJ, et al. Cardiolipin provides an essential activating platform for caspase-8 on mitochondria. J Cell Biol 2008; 183: 681-696.
-
(2008)
J Cell Biol
, vol.183
, pp. 681-696
-
-
Gonzalvez, F.1
Schug, Z.T.2
Houtkooper, R.H.3
MacKenzie, E.D.4
Brooks, D.G.5
Wanders, R.J.6
-
10
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998; 94: 491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
11
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000; 102: 33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
12
-
-
84866087868
-
AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages
-
Pierini R, Juruj C, Perret M, Jones CL, Mangeot P, Weiss DS, et al. AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages. Cell Death Differ 2012; 19: 1709-1721.
-
(2012)
Cell Death Differ
, vol.19
, pp. 1709-1721
-
-
Pierini, R.1
Juruj, C.2
Perret, M.3
Jones, C.L.4
Mangeot, P.5
Weiss, D.S.6
-
13
-
-
84901008921
-
Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex
-
Man SM, Hopkins LJ, Nugent E, Cox S, Gluck IM, Tourlomousis P, et al. Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex. Proc Natl Acad Sci USA 2014; 111: 7403-7408.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 7403-7408
-
-
Man, S.M.1
Hopkins, L.J.2
Nugent, E.3
Cox, S.4
Gluck, I.M.5
Tourlomousis, P.6
-
14
-
-
84887439544
-
Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1beta production
-
Man SM, Tourlomousis P, Hopkins L, Monie TP, Fitzgerald KA, Bryant CE. Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1beta production. J Immunol 2013; 191: 5239-5246.
-
(2013)
J Immunol
, vol.191
, pp. 5239-5246
-
-
Man, S.M.1
Tourlomousis, P.2
Hopkins, L.3
Monie, T.P.4
Fitzgerald, K.A.5
Bryant, C.E.6
-
15
-
-
84926164932
-
Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against aspergillus infection
-
Karki R, Man SM, Malireddi RK, Gurung P, Vogel P, Lamkanfi M, et al. Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against aspergillus infection. Cell Host Microbe 2015; 17: 357-368.
-
(2015)
Cell Host Microbe
, vol.17
, pp. 357-368
-
-
Karki, R.1
Man, S.M.2
Malireddi, R.K.3
Gurung, P.4
Vogel, P.5
Lamkanfi, M.6
-
16
-
-
84907033643
-
Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1beta production in response to beta-glucans and the fungal pathogen, Candida albicans
-
Ganesan S, Rathinam VA, Bossaller L, Army K, Kaiser WJ, Mocarski ES, et al. Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1beta production in response to beta-glucans and the fungal pathogen, Candida albicans. J Immunol 2014; 193: 2519-2530.
-
(2014)
J Immunol
, vol.193
, pp. 2519-2530
-
-
Ganesan, S.1
Rathinam, V.A.2
Bossaller, L.3
Army, K.4
Kaiser, W.J.5
Mocarski, E.S.6
-
17
-
-
84857175933
-
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1beta via a noncanonical caspase-8 inflammasome
-
Gringhuis SI, Kaptein TM, Wevers BA, Theelen B, van der Vlist M, Boekhout T, et al. Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1beta via a noncanonical caspase-8 inflammasome. Nat Immunol 2012; 13: 246-254.
-
(2012)
Nat Immunol
, vol.13
, pp. 246-254
-
-
Gringhuis, S.I.1
Kaptein, T.M.2
Wevers, B.A.3
Theelen, B.4
Van Der Vlist, M.5
Boekhout, T.6
-
18
-
-
84863306899
-
Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis
-
Grgic I, Campanholle G, Bijol V, Wang C, Sabbisetti VS, Ichimura T, et al. Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis. Kidney Int 2012; 82: 172-183.
-
(2012)
Kidney Int
, vol.82
, pp. 172-183
-
-
Grgic, I.1
Campanholle, G.2
Bijol, V.3
Wang, C.4
Sabbisetti, V.S.5
Ichimura, T.6
-
19
-
-
79955846705
-
NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
-
Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, et al. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm Bowel Dis 2011; 17: 1359-1372.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1359-1372
-
-
Hirota, S.A.1
Ng, J.2
Lueng, A.3
Khajah, M.4
Parhar, K.5
Li, Y.6
-
20
-
-
77957887259
-
The NLRP3 inflammasome promotes renal inflammation and contributes to CKD
-
Vilaysane A, Chun J, Seamone ME, Wang W, Chin R, Hirota S, et al. The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J Am Soc Nephrol 2010; 21: 1732-1744.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1732-1744
-
-
Vilaysane, A.1
Chun, J.2
Seamone, M.E.3
Wang, W.4
Chin, R.5
Hirota, S.6
-
21
-
-
84872737232
-
Inflammasome-independent NLRP3 augments TGF-beta signaling in kidney epithelium
-
Wang W, Wang X, Chun J, Vilaysane A, Clark S, French G, et al. Inflammasome-independent NLRP3 augments TGF-beta signaling in kidney epithelium. J Immunol 2013; 190: 1239-1249.
-
(2013)
J Immunol
, vol.190
, pp. 1239-1249
-
-
Wang, W.1
Wang, X.2
Chun, J.3
Vilaysane, A.4
Clark, S.5
French, G.6
-
22
-
-
84903127232
-
A tissuespecific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion
-
Bakker PJ, Butter LM, Claessen N, Teske GJ, Sutterwala FS, Florquin S, et al. A tissuespecific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion. Am J Pathol 2014; 184: 2013-2022.
-
(2014)
Am J Pathol
, vol.184
, pp. 2013-2022
-
-
Bakker, P.J.1
Butter, L.M.2
Claessen, N.3
Teske, G.J.4
Sutterwala, F.S.5
Florquin, S.6
-
23
-
-
78650659200
-
An inflammasomeindependent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury
-
Shigeoka AA, Mueller JL, Kambo A, Mathison JC, King AJ, Hall WF, et al. An inflammasomeindependent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury. J Immunol 2010; 185: 6277-6285.
-
(2010)
J Immunol
, vol.185
, pp. 6277-6285
-
-
Shigeoka, A.A.1
Mueller, J.L.2
Kambo, A.3
Mathison, J.C.4
King, A.J.5
Hall, W.F.6
-
24
-
-
43049152912
-
TNF-Alpha induces two distinct caspase-8 activation pathways
-
Wang L, Du F, Wang X. TNF-Alpha induces two distinct caspase-8 activation pathways. Cell 2008; 133: 693-703.
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
25
-
-
84900333477
-
Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-Associated cIAPs, abrogates TNF-induced NF-kappaB activation, and is active in patient-derived xenograft models
-
Benetatos CA, Mitsuuchi Y, Burns JM, Neiman EM, Condon SM, Yu G, et al. Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-Associated cIAPs, abrogates TNF-induced NF-kappaB activation, and is active in patient-derived xenograft models. Mol Cancer Ther 2014; 13: 867-879.
-
(2014)
Mol Cancer Ther
, vol.13
, pp. 867-879
-
-
Benetatos, C.A.1
Mitsuuchi, Y.2
Burns, J.M.3
Neiman, E.M.4
Condon, S.M.5
Yu, G.6
-
26
-
-
84871125002
-
Cutting edge: FAS (CD95) mediates noncanonical IL-1beta and IL-18 maturation via caspase-8 in an RIP3-independent manner
-
Bossaller L, Chiang PI, Schmidt-Lauber C, Ganesan S, Kaiser WJ, Rathinam VA, et al. Cutting edge: FAS (CD95) mediates noncanonical IL-1beta and IL-18 maturation via caspase-8 in an RIP3-independent manner. J Immunol 2012; 189: 5508-5512.
-
(2012)
J Immunol
, vol.189
, pp. 5508-5512
-
-
Bossaller, L.1
Chiang, P.I.2
Schmidt-Lauber, C.3
Ganesan, S.4
Kaiser, W.J.5
Rathinam, V.A.6
-
27
-
-
84904214756
-
Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome
-
Bracey NA, Gershkovich B, Chun J, Vilaysane A, Meijndert HC, Wright JR Jr., et al. Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome. J Biol Chem 2014; 289: 19571-19584.
-
(2014)
J Biol Chem
, vol.289
, pp. 19571-19584
-
-
Bracey, N.A.1
Gershkovich, B.2
Chun, J.3
Vilaysane, A.4
Meijndert, H.C.5
Wright, J.R.6
-
28
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011; 469: 221-225.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
29
-
-
84882614243
-
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation
-
Iyer SS, He Q, Janczy JR, Elliott EI, Zhong Z, Olivier AK, et al. Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation. Immunity 2013; 39: 311-323.
-
(2013)
Immunity
, vol.39
, pp. 311-323
-
-
Iyer, S.S.1
He, Q.2
Janczy, J.R.3
Elliott, E.I.4
Zhong, Z.5
Olivier, A.K.6
-
30
-
-
0025185463
-
Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis
-
Martin SJ, Lennon SV, Bonham AM, Cotter TG. Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis. J Immunol 1990; 145: 1859-1867.
-
(1990)
J Immunol
, vol.145
, pp. 1859-1867
-
-
Martin, S.J.1
Lennon, S.V.2
Bonham, A.M.3
Cotter, T.G.4
-
31
-
-
0033548603
-
Cycloheximide-induced T-cell death is mediated by a Fas-Associated death domain-dependent mechanism
-
Tang D, Lahti JM, Grenet J, Kidd VJ. Cycloheximide-induced T-cell death is mediated by a Fas-Associated death domain-dependent mechanism. J Biol Chem 1999; 274: 7245-7252.
-
(1999)
J Biol Chem
, vol.274
, pp. 7245-7252
-
-
Tang, D.1
Lahti, J.M.2
Grenet, J.3
Kidd, V.J.4
-
32
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 2007; 14: 1583-1589.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
33
-
-
67349123408
-
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
-
Sato T, Vries RG, Snippert HJ, van de Wetering M, Barker N, Stange DE, et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 2009; 459: 262-265.
-
(2009)
Nature
, vol.459
, pp. 262-265
-
-
Sato, T.1
Vries, R.G.2
Snippert, H.J.3
Van De Wetering, M.4
Barker, N.5
Stange, D.E.6
-
34
-
-
33846532487
-
FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies
-
Milovic-Holm K, Krieghoff E, Jensen K, Will H, Hofmann TG. FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies. EMBO J. 2007; 26: 391-401.
-
(2007)
EMBO J.
, vol.26
, pp. 391-401
-
-
Milovic-Holm, K.1
Krieghoff, E.2
Jensen, K.3
Will, H.4
Hofmann, T.G.5
-
35
-
-
0037040176
-
Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: Role for the bifunctional apoptosis regulator protein
-
Stegh AH, Barnhart BC, Volkland J, Algeciras-Schimnich A, Ke N, Reed JC, et al. Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein. J Biol Chem 2002; 277: 4351-4360.
-
(2002)
J Biol Chem
, vol.277
, pp. 4351-4360
-
-
Stegh, A.H.1
Barnhart, B.C.2
Volkland, J.3
Algeciras-Schimnich, A.4
Ke, N.5
Reed, J.C.6
-
36
-
-
84893354769
-
A novel mitochondrial MAVS/Caspase-8 platform links RNA virus-induced innate antiviral signaling to Bax/Bakindependent apoptosis
-
El Maadidi S, Faletti L, Berg B, Wenzl C, Wieland K, Chen ZJ, et al. A novel mitochondrial MAVS/Caspase-8 platform links RNA virus-induced innate antiviral signaling to Bax/Bakindependent apoptosis. J Immunol 2014; 192: 1171-1183.
-
(2014)
J Immunol
, vol.192
, pp. 1171-1183
-
-
El Maadidi, S.1
Faletti, L.2
Berg, B.3
Wenzl, C.4
Wieland, K.5
Chen, Z.J.6
-
37
-
-
84885437002
-
The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity
-
Park S, Juliana C, Hong S, Datta P, Hwang I, Fernandes-Alnemri T, et al. The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity. J Immunol 2013; 191: 4358-4366.
-
(2013)
J Immunol
, vol.191
, pp. 4358-4366
-
-
Park, S.1
Juliana, C.2
Hong, S.3
Datta, P.4
Hwang, I.5
Fernandes-Alnemri, T.6
-
38
-
-
84876237736
-
The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation
-
Subramanian N, Natarajan K, Clatworthy MR, Wang Z, Germain RN. The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation. Cell 2013; 153: 348-361.
-
(2013)
Cell
, vol.153
, pp. 348-361
-
-
Subramanian, N.1
Natarajan, K.2
Clatworthy, M.R.3
Wang, Z.4
Germain, R.N.5
-
39
-
-
32944468985
-
Gout-Associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-Associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440: 237-241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
40
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 2004; 430: 213-218.
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
-
41
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
-
Kuida K, Lippke JA, Ku G, Harding MW, Livingston DJ, Su MS, et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 1995; 267: 2000-2003.
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
Lippke, J.A.2
Ku, G.3
Harding, M.W.4
Livingston, D.J.5
Su, M.S.6
-
42
-
-
80054857419
-
Long-Term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium
-
Sato T, Stange DE, Ferrante M, Vries RG, Van Es JH, Van den Brink S, et al. Long-Term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. Gastroenterology 2011; 141: 1762-1772.
-
(2011)
Gastroenterology
, vol.141
, pp. 1762-1772
-
-
Sato, T.1
Stange, D.E.2
Ferrante, M.3
Vries, R.G.4
Van Es, J.H.5
Van Den Brink, S.6
|