-
1
-
-
33749522212
-
FLASH is required for histone transcription and S-phase progression
-
Barcaroli D, Bongiorno-Borbone L, Terrinoni A, Hofmann TG, Rossi M, Knight RA, Matera AG, Melino G, De Laurenzi V (2006a) FLASH is required for histone transcription and S-phase progression. Proc Natl Acad Sci USA 103: 14808-14812
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14808-14812
-
-
Barcaroli, D.1
Bongiorno-Borbone, L.2
Terrinoni, A.3
Hofmann, T.G.4
Rossi, M.5
Knight, R.A.6
Matera, A.G.7
Melino, G.8
De Laurenzi, V.9
-
2
-
-
33749520807
-
FLASH is an essential component of Cajal bodies
-
Barcaroli D, Dinsdale D, Neale MH, Bongiorno-Borbone L, Ranalli M, Munarriz E, Sayan AE, McWilliam JM, Smith TM, Fava E, Knight RA, Melino G, De Laurenzi V (2006b) FLASH is an essential component of Cajal bodies. Proc Natl Acad Sci USA 103: 14802-14807
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14802-14807
-
-
Barcaroli, D.1
Dinsdale, D.2
Neale, M.H.3
Bongiorno-Borbone, L.4
Ranalli, M.5
Munarriz, E.6
Sayan, A.E.7
McWilliam, J.M.8
Smith, T.M.9
Fava, E.10
Knight, R.A.11
Melino, G.12
De Laurenzi, V.13
-
3
-
-
1642512435
-
Role of PML and the PML-nuclear body in the control of programmed cell death
-
Bernardi R, Pandolfi PP (2003) Role of PML and the PML-nuclear body in the control of programmed cell death. Oncogene 22: 9048-9057
-
(2003)
Oncogene
, vol.22
, pp. 9048-9057
-
-
Bernardi, R.1
Pandolfi, P.P.2
-
4
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
-
Boldin MP, Goncharov TM, Goltsev YV, Wallach D (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85: 803-815
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
5
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science 296: 550-553
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
6
-
-
3242675057
-
Association of active Caspase 8 with the mitochondrial membrane during apoptosis: Potential roles in cleaving BAP31 and Caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death
-
Chandra D, Choy G, Deng X, Bhatia B, Daniel P, Tang DG (2004) Association of active Caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and Caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death. Mol Cell Biol 24: 6592-6607
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6592-6607
-
-
Chandra, D.1
Choy, G.2
Deng, X.3
Bhatia, B.4
Daniel, P.5
Tang, D.G.6
-
7
-
-
0029965280
-
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis
-
Chinnaiyan AM, Tepper CG, Seldin MF, O'Rourke K, Kischkel FC, Hellbardt S, Krammer PH, Peter ME, Dixit VM (1996) FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis. J Biol Chem 271: 4961-4965
-
(1996)
J Biol Chem
, vol.271
, pp. 4961-4965
-
-
Chinnaiyan, A.M.1
Tepper, C.G.2
Seldin, M.F.3
O'Rourke, K.4
Kischkel, F.C.5
Hellbardt, S.6
Krammer, P.H.7
Peter, M.E.8
Dixit, V.M.9
-
8
-
-
0036791781
-
Viral homologs of BCL-2: Role of apoptosis in the regulation of virus infection
-
Cuconati A, White E (2002) Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection. Genes Dev 16: 2465-2478
-
(2002)
Genes Dev
, vol.16
, pp. 2465-2478
-
-
Cuconati, A.1
White, E.2
-
9
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 494-498
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
10
-
-
33644821166
-
Interactions between DNA viruses, ND10 and the DNA damage response
-
Everett RD (2006) Interactions between DNA viruses, ND10 and the DNA damage response. Cell Microbiol 8: 365-374
-
(2006)
Cell Microbiol
, vol.8
, pp. 365-374
-
-
Everett, R.D.1
-
12
-
-
0030831534
-
CRM1 is responsible for intracellular transport mediated by the nuclear export signal
-
Fukuda M, Asano S, Nakamura T, Adachi M, Yoshida M, Yanagida M, Nishida E (1997) CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature 390: 308-311
-
(1997)
Nature
, vol.390
, pp. 308-311
-
-
Fukuda, M.1
Asano, S.2
Nakamura, T.3
Adachi, M.4
Yoshida, M.5
Yanagida, M.6
Nishida, E.7
-
13
-
-
0034708085
-
Caspase-dependent cleavage and inactivation of the Vav1 proto-oncogene product during apoptosis prevents IL-2 transcription
-
Hofmann TG, Hehner SP, Droge W, Schmitz ML (2000) Caspase-dependent cleavage and inactivation of the Vav1 proto-oncogene product during apoptosis prevents IL-2 transcription. Oncogene 19: 1153-1163
-
(2000)
Oncogene
, vol.19
, pp. 1153-1163
-
-
Hofmann, T.G.1
Hehner, S.P.2
Droge, W.3
Schmitz, M.L.4
-
14
-
-
0036141392
-
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
-
Hofmann TG, Moller A, Sirma H, Zentgraf H, Taya Y, Droge W, Will H, Schmitz ML (2002) Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat Cell Biol 4: 1-10
-
(2002)
Nat Cell Biol
, vol.4
, pp. 1-10
-
-
Hofmann, T.G.1
Moller, A.2
Sirma, H.3
Zentgraf, H.4
Taya, Y.5
Droge, W.6
Will, H.7
Schmitz, M.L.8
-
15
-
-
0346147033
-
Body language: The function of PML nuclear bodies in apoptosis regulation
-
Hofmann TG, Will H (2003) Body language: the function of PML nuclear bodies in apoptosis regulation. Cell Death Differ 10: 1290-1299
-
(2003)
Cell Death Differ
, vol.10
, pp. 1290-1299
-
-
Hofmann, T.G.1
Will, H.2
-
16
-
-
0033614347
-
The CED-4-homologous protein FLASH is involved in Fasmediated activation of caspase-8 during apoptosis
-
Imai Y, Kimura T, Murakami A, Yajima N, Sakamaki K, Yonehara S (1999) The CED-4-homologous protein FLASH is involved in Fasmediated activation of caspase-8 during apoptosis. Nature 398: 777-785
-
(1999)
Nature
, vol.398
, pp. 777-785
-
-
Imai, Y.1
Kimura, T.2
Murakami, A.3
Yajima, N.4
Sakamaki, K.5
Yonehara, S.6
-
17
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schroter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J (1997) Inhibition of death receptor signals by cellular FLIP. Nature 388: 190-195
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
Bodmer, J.L.7
Schroter, M.8
Burns, K.9
Mattmann, C.10
Rimoldi, D.11
French, L.E.12
Tschopp, J.13
-
18
-
-
0032721540
-
PML is critical for ND10 formation and recruits the PML-interacting protein Daxx to this nuclear structure when modified by SUMO-1
-
Ishov AM, Sotnikov AG, Negorev D, Vladimirova OV, Neff N, Kamitani T, Yeh ET, Strauss III JF, Maul GG (1999) PML is critical for ND10 formation and recruits the PML-interacting protein Daxx to this nuclear structure when modified by SUMO-1. J Cell Biol 147: 221-234
-
(1999)
J Cell Biol
, vol.147
, pp. 221-234
-
-
Ishov, A.M.1
Sotnikov, A.G.2
Negorev, D.3
Vladimirova, O.V.4
Neff, N.5
Kamitani, T.6
Yeh, E.T.7
Strauss III, J.F.8
Maul, G.G.9
-
19
-
-
0037474334
-
Tumor necrosis factor alpha receptorand Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators
-
Kino T, Chrousos GP (2003) Tumor necrosis factor alpha receptorand Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators. J Biol Chem 278: 3023-3029
-
(2003)
J Biol Chem
, vol.278
, pp. 3023-3029
-
-
Kino, T.1
Chrousos, G.P.2
-
20
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer PH, Peter ME (1995) Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J 14: 5579-5588
-
(1995)
EMBO J
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
Krammer, P.H.6
Peter, M.E.7
-
21
-
-
0033554702
-
Apoptosis. Searching for FLASH domains
-
discussion 662-663
-
Koonin EV, Aravind L, Hofmann K, Tschopp J, Dixit VM (1999) Apoptosis. Searching for FLASH domains. Nature 401: 662; discussion 662-663
-
(1999)
Nature
, vol.401
, pp. 662
-
-
Koonin, E.V.1
Aravind, L.2
Hofmann, K.3
Tschopp, J.4
Dixit, V.M.5
-
22
-
-
0034641898
-
CD95's deadly mission in the immune system
-
Krammer PH (2000) CD95's deadly mission in the immune system. Nature 407: 789-795
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
24
-
-
27144523216
-
Mitochondrial localization of p53 during adenovirus infection and regulation of its activity by E1B-19K
-
Lomonosova E, Subramanian T, Chinnadurai G (2005) Mitochondrial localization of p53 during adenovirus infection and regulation of its activity by E1B-19K. Oncogene 24: 6796-6808
-
(2005)
Oncogene
, vol.24
, pp. 6796-6808
-
-
Lomonosova, E.1
Subramanian, T.2
Chinnadurai, G.3
-
25
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME, Dixit VM (1996) FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85: 817-827
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
Mann, M.11
Krammer, P.H.12
Peter, M.E.13
Dixit, V.M.14
-
26
-
-
0033396491
-
Fas ligand-induced apoptosis
-
Nagata S (1999) Fas ligand-induced apoptosis. Annu Rev Genet 33: 29-55
-
(1999)
Annu Rev Genet
, vol.33
, pp. 29-55
-
-
Nagata, S.1
-
27
-
-
0035969107
-
Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depot
-
Negorev D, Maul GG (2001) Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depot. Oncogene 20: 7234-7242
-
(2001)
Oncogene
, vol.20
, pp. 7234-7242
-
-
Negorev, D.1
Maul, G.G.2
-
28
-
-
1342265730
-
DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor-mediated transcription in hippocampal cells - toward a basis for the opposite actions elicited by two nuclear receptors?
-
Obradovic D, Tirard M, Nemethy Z, Hirsch O, Gronemeyer H, Almeida OF (2004) DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor-mediated transcription in hippocampal cells - toward a basis for the opposite actions elicited by two nuclear receptors? Mol Pharmacol 65: 761-769
-
(2004)
Mol Pharmacol
, vol.65
, pp. 761-769
-
-
Obradovic, D.1
Tirard, M.2
Nemethy, Z.3
Hirsch, O.4
Gronemeyer, H.5
Almeida, O.F.6
-
29
-
-
0032100771
-
E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE
-
Perez D, White E (1998) E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE. J Cell Biol 141: 1255-1266
-
(1998)
J Cell Biol
, vol.141
, pp. 1255-1266
-
-
Perez, D.1
White, E.2
-
31
-
-
0035896592
-
Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation
-
Qin ZH, Wang Y, Kikly KK, Sapp E, Kegel KB, Aronin N, DiFiglia M (2001) Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation. J Biol Chem 276: 8079-8086
-
(2001)
J Biol Chem
, vol.276
, pp. 8079-8086
-
-
Qin, Z.H.1
Wang, Y.2
Kikly, K.K.3
Sapp, E.4
Kegel, K.B.5
Aronin, N.6
DiFiglia, M.7
-
32
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C, Fulda S, Srinivasan A, Friesen C, Li F, Tomaselli KJ, Debatin KM, Krammer PH, Peter ME (1998) Two CD95 (APO-1/Fas) signaling pathways. EMBO J 17: 1675-1687
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
-
33
-
-
0030826338
-
FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b
-
Scaffidi C, Medema JP, Krammer PH, Peter ME (1997) FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b. J Biol Chem 272: 26953-26958
-
(1997)
J Biol Chem
, vol.272
, pp. 26953-26958
-
-
Scaffidi, C.1
Medema, J.P.2
Krammer, P.H.3
Peter, M.E.4
-
34
-
-
0037040176
-
Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: Role for the bifunctional apoptosis regulator protein
-
Stegh AH, Barnhart BC, Volkland J, Algeciras-Schimnich A, Ke N, Reed JC, Peter ME (2002) Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein. J Biol Chem 277: 4351-4360
-
(2002)
J Biol Chem
, vol.277
, pp. 4351-4360
-
-
Stegh, A.H.1
Barnhart, B.C.2
Volkland, J.3
Algeciras-Schimnich, A.4
Ke, N.5
Reed, J.C.6
Peter, M.E.7
-
35
-
-
0033927556
-
Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis
-
Stegh AH, Herrmann H, Lampel S, Weisenberger D, Andra K, Seper M, Wiche G, Krammer PH, Peter ME (2000) Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis. Mol Cell Biol 20: 5665-5679
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5665-5679
-
-
Stegh, A.H.1
Herrmann, H.2
Lampel, S.3
Weisenberger, D.4
Andra, K.5
Seper, M.6
Wiche, G.7
Krammer, P.H.8
Peter, M.E.9
-
36
-
-
0033617169
-
The nuclear dot protein Sp100: Characterization of domains necessary for dimerization, subcellular localization and modification by small ubiquitin-like modifiers
-
Sternsdorf T, Jensen K, Reich B, Will H (1999) The nuclear dot protein Sp100: characterization of domains necessary for dimerization, subcellular localization and modification by small ubiquitin-like modifiers. J Biol Chem 274: 12555-12566
-
(1999)
J Biol Chem
, vol.274
, pp. 12555-12566
-
-
Sternsdorf, T.1
Jensen, K.2
Reich, B.3
Will, H.4
-
37
-
-
0031426631
-
Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1
-
Sternsdorf T, Jensen K, Will H (1997) Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1. J Cell Biol 139: 1621-1634
-
(1997)
J Cell Biol
, vol.139
, pp. 1621-1634
-
-
Sternsdorf, T.1
Jensen, K.2
Will, H.3
-
39
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB (1997) Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 91: 627-637
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
Schumacker, P.T.4
Thompson, C.B.5
-
40
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev EE, Schuchmann M, Luria V, Chiannilkulchai N, Beckmann JS, Mett IL, Rebrikov D, Brodianski VM, Kemper OC, Kollet O, Lapidot T, Soffer D, Sobe T, Avraham KB, Goncharov T, Holtmann H, Lonai P,Wallach D (1998) Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 9: 267-276
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
Lapidot, T.11
Soffer, D.12
Sobe, T.13
Avraham, K.B.14
Goncharov, T.15
Holtmann, H.16
Lonai, P.17
Wallach, D.18
-
41
-
-
0035890085
-
The expanding role of mitochondria in apoptosis
-
Wang X (2001) The expanding role of mitochondria in apoptosis. Genes Dev 15: 2922-2933
-
(2001)
Genes Dev
, vol.15
, pp. 2922-2933
-
-
Wang, X.1
-
42
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ (2001) Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292: 727-730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
43
-
-
0343776952
-
Role of SUMO-1-modified PML in nuclear body formation
-
Zhong S, Müller S, Ronchetti S, Freemont PS, Dejean A, Pandolfi PP (2000) Role of SUMO-1-modified PML in nuclear body formation. Blood 95: 2748-2752
-
(2000)
Blood
, vol.95
, pp. 2748-2752
-
-
Zhong, S.1
Müller, S.2
Ronchetti, S.3
Freemont, P.S.4
Dejean, A.5
Pandolfi, P.P.6
|