Inflammation increases NOTCH1 activity via MMP9 and is counteracted by Eicosapentaenoic Acid-free fatty acid in colon cancer cells

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Fazio, Chiara ^a,b   Piazzi, Giulia ^a,b   Vitaglione, Paola ^c   Fogliano, Vincenzo ^d   Munarini, Alessandra ^a,b   Prossomariti, Anna ^a,b   Milazzo, Maddalena ^b   D'Angelo, Leonarda ^a,b   Napolitano, Manuela ^a,b   Chieco, Pasquale ^b   Belluzzi, Andrea ^b   Bazzoli, Franco ^a   Ricciardiello, Luigi ^a,b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CONDITIONED MEDIUM; CYTOKINE; GELATINASE B; ICOSAPENTAENOIC ACID; LIPOPOLYSACCHARIDE; MMP9 PROTEIN, HUMAN; NOTCH1 PROTEIN, HUMAN; NOTCH1 RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE;

AGONISTS; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL LINE; CELL MOTION; CONDITIONED MEDIUM; CYTOLOGY; DRUG EFFECTS; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; GENETICS; HCT 116 CELL LINE; HT-29 CELL LINE; HUMAN; INFLAMMATION; METABOLISM; MONOCYTE; PHARMACOLOGY; SECRETION (PROCESS); SIGNAL TRANSDUCTION;

CELL DIFFERENTIATION; CELL LINE; CELL MOVEMENT; CULTURE MEDIA, CONDITIONED; CYTOKINES; EICOSAPENTAENOIC ACID; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; HCT116 CELLS; HT29 CELLS; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASE 9; MONOCYTES; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE;

EID: 84958581411     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20670     Document Type: Article

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