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Volumn 34, Issue 27, 2015, Pages 3493-3503

Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 6; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; STAT3 PROTEIN; STAT3 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR ALPHA;

EID: 85028276122     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/ONC.2014.286     Document Type: Article
Times cited : (475)

References (46)
  • 2
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759–767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 3
    • 0035080617 scopus 로고    scopus 로고
    • The risk of colorectal cancer in ulcerative colitis: A meta-analysis
    • Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 2001; 48: 526–535.
    • (2001) Gut , vol.48 , pp. 526-535
    • Eaden, J.A.1    Abrams, K.R.2    Mayberry, J.F.3
  • 4
    • 58649108302 scopus 로고    scopus 로고
    • IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
    • Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 2009; 15: 103–113.
    • (2009) Cancer Cell , vol.15 , pp. 103-113
    • Grivennikov, S.1    Karin, E.2    Terzic, J.3    Mucida, D.4    Yu, G.Y.5    Vallabhapurapu, S.6
  • 5
    • 84868615556 scopus 로고    scopus 로고
    • IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
    • Huber S, Gagliani N, Zenewicz LA, Huber FJ, Bosurgi L, Hu B et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 2012; 491: 259–263.
    • (2012) Nature , vol.491 , pp. 259-263
    • Huber, S.1    Gagliani, N.2    Zenewicz, L.A.3    Huber, F.J.4    Bosurgi, L.5    Hu, B.6
  • 7
    • 80655125038 scopus 로고    scopus 로고
    • Interleukin 21 controls tumour growth and tumour immunosurveillance in colitis-associated tumorigenesis in mice
    • Jauch D, Martin M, Schiechl G, Kesselring R, Schlitt HJ, Geissler EK et al. Interleukin 21 controls tumour growth and tumour immunosurveillance in colitis-associated tumorigenesis in mice. Gut 2011; 60: 1678–1686.
    • (2011) Gut , vol.60 , pp. 1678-1686
    • Jauch, D.1    Martin, M.2    Schiechl, G.3    Kesselring, R.4    Schlitt, H.J.5    Geissler, E.K.6
  • 8
    • 84879571464 scopus 로고    scopus 로고
    • Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
    • Kirchberger S, Royston DJ, Boulard O, Thornton E, Franchini F, Szabady RL et al. Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model. J Exp Med 2013; 210: 917–931.
    • (2013) J Exp Med , vol.210 , pp. 917-931
    • Kirchberger, S.1    Royston, D.J.2    Boulard, O.3    Thornton, E.4    Franchini, F.5    Szabady, R.L.6
  • 9
    • 38849171267 scopus 로고    scopus 로고
    • Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis
    • Popivanova BK, Kitamura K, Wu Y, Kondo T, Kagaya T, Kaneko S et al. Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis. J Clin Invest 2008; 118: 560–570.
    • (2008) J Clin Invest , vol.118 , pp. 560-570
    • Popivanova, B.K.1    Kitamura, K.2    Wu, Y.3    Kondo, T.4    Kagaya, T.5    Kaneko, S.6
  • 10
    • 80055105733 scopus 로고    scopus 로고
    • Involvement of interleukin-21 in the regulation of colitis-associated colon cancer
    • Stolfi C, Rizzo A, Franze E, Rotondi A, Fantini MC, Sarra M et al. Involvement of interleukin-21 in the regulation of colitis-associated colon cancer. J Exp Med 2011; 208: 2279–2290.
    • (2011) J Exp Med , vol.208 , pp. 2279-2290
    • Stolfi, C.1    Rizzo, A.2    Franze, E.3    Rotondi, A.4    Fantini, M.C.5    Sarra, M.6
  • 11
    • 84879076366 scopus 로고    scopus 로고
    • The split nature of tumor-infiltrating leukocytes Implications for cancer surveillance and immunotherapy
    • Lanca T, Silva-Santos B. The split nature of tumor-infiltrating leukocytes Implications for cancer surveillance and immunotherapy. Oncoimmunology 2012; 1: 717–725.
    • (2012) Oncoimmunology , vol.1 , pp. 717-725
    • Lanca, T.1    Silva-Santos, B.2
  • 12
    • 84866936329 scopus 로고    scopus 로고
    • The dual role of inflammation in colon carcinogenesis
    • Monteleone G, Pallone F, Stolfi C. The dual role of inflammation in colon carcinogenesis. Int J Mol Sci 2012; 13: 11071–11084.
    • (2012) Int J Mol Sci , vol.13 , pp. 11071-11084
    • Monteleone, G.1    Pallone, F.2    Stolfi, C.3
  • 13
    • 0032125574 scopus 로고    scopus 로고
    • IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: Requirement of STAT1 protein for up-regulation of Fas and FasL expression
    • Xu X, Fu XY, Plate J, Chong AS. IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression. Cancer Res 1998; 58: 2832–2837.
    • (1998) Cancer Res , vol.58 , pp. 2832-2837
    • Xu, X.1    Fu, X.Y.2    Plate, J.3    Chong, A.S.4
  • 14
    • 0018869252 scopus 로고
    • Enhancement of mouse natural killer cell activity by type II interferon
    • Senik A, Stefanos S, Kolb JP, Lucero M, Falcoff E. Enhancement of mouse natural killer cell activity by type II interferon. Ann Immunol (Paris) 1980; 131C: 349–361.
    • (1980) Ann Immunol (Paris) , vol.131C , pp. 349-361
    • Senik, A.1    Stefanos, S.2    Kolb, J.P.3    Lucero, M.4    Falcoff, E.5
  • 15
    • 0033909434 scopus 로고    scopus 로고
    • Immune-inflammatory mechanisms in IFNgammamediated anti-tumor activity
    • Tannenbaum CS, Hamilton TA. Immune-inflammatory mechanisms in IFNgammamediated anti-tumor activity. Semin Cancer Biol 2000; 10: 113–123.
    • (2000) Semin Cancer Biol , vol.10 , pp. 113-123
    • Tannenbaum, C.S.1    Hamilton, T.A.2
  • 16
    • 0036645530 scopus 로고    scopus 로고
    • Suppression of lymphoma and epithelial malignancies effected by interferon gamma
    • Street SE, Trapani JA, MacGregor D, Smyth MJ. Suppression of lymphoma and epithelial malignancies effected by interferon gamma. J Exp Med 2002; 196: 129–134.
    • (2002) J Exp Med , vol.196 , pp. 129-134
    • Street, S.E.1    Trapani, J.A.2    Macgregor, D.3    Smyth, M.J.4
  • 17
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pages C et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006; 313: 1960–1964.
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5    Lagorce-Pages, C.6
  • 18
    • 84892476369 scopus 로고    scopus 로고
    • Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis
    • Song X, Gao H, Lin Y, Yao Y, Zhu S, Wang J et al. Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis. Immunity 2014; 40: 140–152.
    • (2014) Immunity , vol.40 , pp. 140-152
    • Song, X.1    Gao, H.2    Lin, Y.3    Yao, Y.4    Zhu, S.5    Wang, J.6
  • 19
    • 84900482064 scopus 로고    scopus 로고
    • GammadeltaT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer
    • Wu P, Wu D, Ni C, Ye J, Chen W, Hu G et al. GammadeltaT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer. Immunity 2014; 40: 785–800.
    • (2014) Immunity , vol.40 , pp. 785-800
    • Wu, P.1    Wu, D.2    Ni, C.3    Ye, J.4    Chen, W.5    Hu, G.6
  • 20
    • 84900459331 scopus 로고    scopus 로고
    • IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L
    • Kryczek I, Lin Y, Nagarsheth N, Peng D, Zhao L, Zhao E et al. IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L. Immunity 2014; 40: 772–784.
    • (2014) Immunity , vol.40 , pp. 772-784
    • Kryczek, I.1    Lin, Y.2    Nagarsheth, N.3    Peng, D.4    Zhao, L.5    Zhao, E.6
  • 21
    • 84868613705 scopus 로고    scopus 로고
    • Adenomalinked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
    • Grivennikov SI, Wang K, Mucida D, Stewart CA, Schnabl B, Jauch D et al. Adenomalinked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 2012; 491: 254–258.
    • (2012) Nature , vol.491 , pp. 254-258
    • Grivennikov, S.I.1    Wang, K.2    Mucida, D.3    Stewart, C.A.4    Schnabl, B.5    Jauch, D.6
  • 24
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: Impact on clinical outcome
    • Fridman WH, Pages F, Sautes-Fridman C, Galon J. The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 2012; 12: 298–306.
    • (2012) Nat Rev Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Sautes-Fridman, C.3    Galon, J.4
  • 25
    • 79951815749 scopus 로고    scopus 로고
    • Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer
    • Tosolini M, Kirilovsky A, Mlecnik B, Fredriksen T, Mauger S, Bindea G et al. Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. Cancer Res 2011; 71: 1263–1271.
    • (2011) Cancer Res , vol.71 , pp. 1263-1271
    • Tosolini, M.1    Kirilovsky, A.2    Mlecnik, B.3    Fredriksen, T.4    Mauger, S.5    Bindea, G.6
  • 26
    • 77549083560 scopus 로고    scopus 로고
    • Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer
    • Grivennikov SI, Karin M. Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer. Cytokine Growth Factor Rev 2010; 21: 11–19.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 11-19
    • Grivennikov, S.I.1    Karin, M.2
  • 27
    • 84862193781 scopus 로고    scopus 로고
    • Orally bioavailable smallmolecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
    • Zhang X, Yue P, Page BD, Li T, Zhao W, Namanja AT et al. Orally bioavailable smallmolecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proc Natl Acad Sci USA 2012; 109: 9623–9628.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 9623-9628
    • Zhang, X.1    Yue, P.2    Page, B.D.3    Li, T.4    Zhao, W.5    Namanja, A.T.6
  • 28
    • 34848902667 scopus 로고    scopus 로고
    • Green tea selectively targets initial stages of intestinal carcinogenesis in the AOM-ApcMin mouse model
    • Issa AY, Volate SR, Muga SJ, Nitcheva D, Smith T, Wargovich MJ. Green tea selectively targets initial stages of intestinal carcinogenesis in the AOM-ApcMin mouse model. Carcinogenesis 2007; 28: 1978–1984.
    • (2007) Carcinogenesis , vol.28 , pp. 1978-1984
    • Issa, A.Y.1    Volate, S.R.2    Muga, S.J.3    Nitcheva, D.4    Smith, T.5    Wargovich, M.J.6
  • 29
    • 84881534116 scopus 로고    scopus 로고
    • Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically
    • Putoczki TL, Thiem S, Loving A, Busuttil RA, Wilson NJ, Ziegler PK et al. Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically. Cancer Cell 2013; 24: 257–271.
    • (2013) Cancer Cell , vol.24 , pp. 257-271
    • Putoczki, T.L.1    Thiem, S.2    Loving, A.3    Busuttil, R.A.4    Wilson, N.J.5    Ziegler, P.K.6
  • 30
    • 84873696767 scopus 로고    scopus 로고
    • Early signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsets
    • Yamane H, Paul WE. Early signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsets. Immunol Rev 2013; 252: 12–23.
    • (2013) Immunol Rev , vol.252 , pp. 12-23
    • Yamane, H.1    Paul, W.E.2
  • 32
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
    • Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006; 126: 1121–1133.
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6
  • 35
    • 63249092765 scopus 로고    scopus 로고
    • Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors
    • Lee H, Herrmann A, Deng JH, Kujawski M, Niu G, Li Z et al. Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. Cancer Cell 2009; 15: 283–293.
    • (2009) Cancer Cell , vol.15 , pp. 283-293
    • Lee, H.1    Herrmann, A.2    Deng, J.H.3    Kujawski, M.4    Niu, G.5    Li, Z.6
  • 36
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004; 118: 285–296.
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3    Park, J.M.4    Li, Z.W.5    Egan, L.J.6
  • 37
    • 58649101347 scopus 로고    scopus 로고
    • Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cellcycle progression during colitis-associated tumorigenesis
    • Bollrath J, Phesse TJ, von Burstin VA, Putoczki T, Bennecke M, Bateman T et al. Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cellcycle progression during colitis-associated tumorigenesis. Cancer Cell 2009; 15: 91–102.
    • (2009) Cancer Cell , vol.15 , pp. 91-102
    • Bollrath, J.1    Phesse, T.J.2    von Burstin, V.A.3    Putoczki, T.4    Bennecke, M.5    Bateman, T.6
  • 38
    • 33750435582 scopus 로고    scopus 로고
    • NF-kappaB and the immune response
    • Hayden MS, West AP, Ghosh S. NF-kappaB and the immune response. Oncogene 2006; 25: 6758–6780.
    • (2006) Oncogene , vol.25 , pp. 6758-6780
    • Hayden, M.S.1    West, A.P.2    Ghosh, S.3
  • 39
    • 84898921083 scopus 로고    scopus 로고
    • STAT3 target genes relevant to human cancers
    • Carpenter RL, Lo HW. STAT3 target genes relevant to human cancers. Cancers (Basel) 2014; 6: 897–925.
    • (2014) Cancers (Basel) , vol.6 , pp. 897-925
    • Carpenter, R.L.1    Lo, H.W.2
  • 40
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
    • Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 2007; 7: 41–51.
    • (2007) Nat Rev Immunol , vol.7 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 41
    • 40749123066 scopus 로고    scopus 로고
    • Autocrine regulation of IL-21 production in human T lymphocytes
    • Caprioli F, Sarra M, Caruso R, Stolfi C, Fina D, Sica G et al. Autocrine regulation of IL-21 production in human T lymphocytes. J Immunol 2008; 180: 1800–1807.
    • (2008) J Immunol , vol.180 , pp. 1800-1807
    • Caprioli, F.1    Sarra, M.2    Caruso, R.3    Stolfi, C.4    Fina, D.5    Sica, G.6
  • 43
    • 84876297224 scopus 로고    scopus 로고
    • Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases
    • Wang K, Grivennikov SI, Karin M. Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases. Ann Rheum Dis2013; 72(Suppl 2): ii100–ii103.
    • (2013) Ann Rheum Dis , vol.72 , pp. ii100-ii103
    • Wang, K.1    Grivennikov, S.I.2    Karin, M.3
  • 44
    • 0030995575 scopus 로고    scopus 로고
    • Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
    • Monteleone G, Biancone L, Marasco R, Morrone G, Marasco O, Luzza F et al. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 1997; 112: 1169–1178.
    • (1997) Gastroenterology , vol.112 , pp. 1169-1178
    • Monteleone, G.1    Biancone, L.2    Marasco, R.3    Morrone, G.4    Marasco, O.5    Luzza, F.6
  • 45
    • 37849007849 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent and-independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid
    • Stolfi C, Fina D, Caruso R, Caprioli F, Sarra M, Fantini MC et al. Cyclooxygenase-2-dependent and-independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid. Biochem Pharmacol 2008; 75: 668–676.
    • (2008) Biochem Pharmacol , vol.75 , pp. 668-676
    • Stolfi, C.1    Fina, D.2    Caruso, R.3    Caprioli, F.4    Sarra, M.5    Fantini, M.C.6
  • 46
    • 21044456328 scopus 로고    scopus 로고
    • In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy
    • Becker C, Fantini MC, Wirtz S, Nikolaev A, Kiesslich R, Lehr HA et al. In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy. Gut 2005; 54: 950–954.
    • (2005) Gut , vol.54 , pp. 950-954
    • Becker, C.1    Fantini, M.C.2    Wirtz, S.3    Nikolaev, A.4    Kiesslich, R.5    Lehr, H.A.6


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