Dll1- and Dll4-mediated notch signaling are required for homeostasis of intestinal stem cells

Gastroenterology

Volumn 140, Issue 4, 2011, Pages 1230-1240.e7

  Pellegrinet, Luca ^a   Rodilla, Veronica ^b   Liu, Zhenyi ^c   Chen, Shuang ^c   Koch, Ute ^a   Espinosa, Lluis ^b   Kaestner, Klaus H ^d   Kopan, Raphael ^c   Lewis, Julian ^e   Radtke, Freddy ^a  

^a EPFL   (Switzerland)

^b INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Gene Regulation; GI Development; Intestinal Stem Cells; Knockout Mice

Indexed keywords

JAGGED1; KRUPPEL LIKE FACTOR 4; LIGAND; NOTCH RECEPTOR; NOTCH1 RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DLL1; TRANSCRIPTION FACTOR DLL4; UNCLASSIFIED DRUG;

ARTICLE; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; DUODENUM; GOBLET CELL; HOMEOSTASIS; ILEUM; IN VIVO STUDY; INTESTINAL STEM CELL; INTESTINE CELL; INTESTINE EPITHELIUM; JEJUNUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMALL INTESTINE; STEM CELL; TRANSGENIC MOUSE; WILD TYPE;

EID: 79953204955     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.01.005     Document Type: Article

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