Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner

Cell Reports

Volumn 14, Issue 5, 2016, Pages 1206-1217

  Zhang, Lianjun ^a   Tschumi, Benjamin O ^a   Lopez Mejia, Isabel C ^a   Oberle, Susanne G ^b   Meyer, Marten ^c   Samson, Guerric ^a   Rüegg, Markus A ^d   Hall, Michael N ^d   Fajas, Lluis ^a   Zehn, Dietmar ^b   Mach, Jean Pierre ^a   Donda, Alena ^a   Romero, Pedro ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b Swiss Vaccine Research Institute   (Switzerland)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY OF BASEL   (Switzerland)

Author keywords

CD8 T cell; Foxo1; Infection; MTORC2; Rictor

Indexed keywords

INTERLEUKIN 2; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR T BET; CARRIER PROTEIN; EOMES PROTEIN, MOUSE; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; RICTOR PROTEIN, MOUSE; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

ANIMAL CELL; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME REPRESSION; FATTY ACID OXIDATION; IMMUNOTHERAPY; LYMPHOCYTE DIFFERENTIATION; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; UPREGULATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL DIFFERENTIATION; CELL NUCLEUS; CYTOLOGY; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM;

ANIMALS; CARRIER PROTEINS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL NUCLEUS; FORKHEAD BOX PROTEIN O1; FORKHEAD TRANSCRIPTION FACTORS; IMMUNOLOGIC MEMORY; INTERLEUKIN-2; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; T-BOX DOMAIN PROTEINS; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC;

EID: 84957963858     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.12.095     Document Type: Article

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