메뉴 건너뛰기




Volumn 82, Issue 7, 2014, Pages 3045-3057

Role of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection

Author keywords

[No Author keywords available]

Indexed keywords

EOMESODERMIN; PROTEIN; TUBEROUS SCLEROSIS 1 PROTEIN; UNCLASSIFIED DRUG;

EID: 84903136755     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01816-14     Document Type: Article
Times cited : (19)

References (61)
  • 1
    • 34247849183 scopus 로고    scopus 로고
    • Effector and memory CTL differentiation
    • Williams MA, Bevan MJ. 2007. Effector and memory CTL differentiation. Annu. Rev. Immunol. 25:171-192. http://dx.doi.org/10.1146/annurev.immunol.25.022106.141548.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 171-192
    • Williams, M.A.1    Bevan, M.J.2
  • 2
    • 80051873375 scopus 로고    scopus 로고
    • + T cells: foot soldiers of the immune system
    • + T cells: foot soldiers of the immune system. Immunity 35:161-168. http://dx.doi.org/10.1016/j.immuni.2011.07.010.
    • (2011) Immunity , vol.35 , pp. 161-168
    • Zhang, N.1    Bevan, M.J.2
  • 4
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, Ahmed R. 2003. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 4:1191-1198. http://dx.doi.org/10.1038/ni1009.
    • (2003) Nat. Immunol. , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 6
    • 33644763937 scopus 로고    scopus 로고
    • +-T-cell contraction is influenced by the peak of Listeria monocytogenes infection and antigen display
    • +-T-cell contraction is influenced by the peak of Listeria monocytogenes infection and antigen display. Infect. Immun. 74:1528-1536. http://dx.doi.org/10.1128/IAI.74.3.1528-1536.2006.
    • (2006) Infect. Immun. , vol.74 , pp. 1528-1536
    • Porter, B.B.1    Harty, J.T.2
  • 7
    • 84870696545 scopus 로고    scopus 로고
    • Anti-viral CD8 T cells and the cytokines that they love
    • Cox MA, Kahan SM, Zajac AJ. 2013. Anti-viral CD8 T cells and the cytokines that they love. Virology 435:157-169. http://dx.doi.org/10.1016/j.virol.2012.09.012.
    • (2013) Virology , vol.435 , pp. 157-169
    • Cox, M.A.1    Kahan, S.M.2    Zajac, A.J.3
  • 8
    • 4444253689 scopus 로고    scopus 로고
    • + T cell contraction is controlled by early inflammation
    • + T cell contraction is controlled by early inflammation. Nat. Immunol. 5:809-817. http://dx.doi.org/10.1038/ni1098.
    • (2004) Nat. Immunol. , vol.5 , pp. 809-817
    • Badovinac, V.P.1    Porter, B.B.2    Harty, J.T.3
  • 10
    • 84874915030 scopus 로고    scopus 로고
    • The requirement of linker for activation of T cells in the primary and memory responses of CD8 T cells
    • Ou-Yang CW, Zhu M, Sullivan SA, Fuller DM, Zhang W. 2013. The requirement of linker for activation of T cells in the primary and memory responses of CD8 T cells. J. Immunol. 190:2938-2947. http://dx.doi.org/10.4049/jimmunol.1203163.
    • (2013) J. Immunol. , vol.190 , pp. 2938-2947
    • Ou-Yang, C.W.1    Zhu, M.2    Sullivan, S.A.3    Fuller, D.M.4    Zhang, W.5
  • 11
    • 33746010366 scopus 로고    scopus 로고
    • Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation
    • Thompson LJ, Kolumam GA, Thomas S, Murali-Krishna K. 2006. Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation. J. Immunol. 177:1746-1754. http://dx.doi.org/10.4049/jimmunol.177.3.1746.
    • (2006) J. Immunol. , vol.177 , pp. 1746-1754
    • Thompson, L.J.1    Kolumam, G.A.2    Thomas, S.3    Murali-Krishna, K.4
  • 12
    • 84864020108 scopus 로고    scopus 로고
    • Signal 3 cytokines as modulators of primary immune responses during infections: the interplay of type I IFN and IL-12 in CD8 T cell responses
    • e40865
    • Keppler SJ, Rosenits K, Koegl T, Vucikuja S, Aichele P. 2012. Signal 3 cytokines as modulators of primary immune responses during infections: the interplay of type I IFN and IL-12 in CD8 T cell responses. PLoS One 7:e40865. http://dx.doi.org/10.1371/journal.pone.0040865.
    • (2012) PLoS One , vol.7
    • Keppler, S.J.1    Rosenits, K.2    Koegl, T.3    Vucikuja, S.4    Aichele, P.5
  • 13
    • 78650510609 scopus 로고    scopus 로고
    • mTOR: from growth signal integration to cancer, diabetes and ageing
    • Zoncu R, Efeyan A, Sabatini DM. 2011. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol. 12:21-35. http://dx.doi.org/10.1038/nrm3025.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 14
    • 78649348967 scopus 로고    scopus 로고
    • Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
    • Sengupta S, Peterson TR, Sabatini DM. 2010. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol. Cell 40:310-322. http://dx.doi.org/10.1016/j.molcel.2010.09.026.
    • (2010) Mol. Cell , vol.40 , pp. 310-322
    • Sengupta, S.1    Peterson, T.R.2    Sabatini, D.M.3
  • 15
    • 34347220473 scopus 로고    scopus 로고
    • Defining the role of mTOR in cancer
    • Guertin DA, Sabatini DM. 2007. Defining the role of mTOR in cancer. Cancer Cell 12:9-22. http://dx.doi.org/10.1016/j.ccr.2007.05.008.
    • (2007) Cancer Cell , vol.12 , pp. 9-22
    • Guertin, D.A.1    Sabatini, D.M.2
  • 18
    • 74649085700 scopus 로고    scopus 로고
    • + T cell fate by regulating the expres-sion of transcription factors T-bet and eomesodermin
    • + T cell fate by regulating the expres-sion of transcription factors T-bet and eomesodermin. Immunity 32:67-78. http://dx.doi.org/10.1016/j.immuni.2009.10.010.
    • (2010) Immunity , vol.32 , pp. 67-78
    • Rao, R.R.1    Li, Q.2    Odunsi, K.3    Shrikant, P.A.4
  • 19
  • 20
    • 84863654925 scopus 로고    scopus 로고
    • The role and regulation of mTOR in T-lymphocyte function
    • O'Brien TF, Zhong XP. 2012. The role and regulation of mTOR in T-lymphocyte function. Arch. Immunol. Ther. Exp. 60:173-181. http://dx.doi.org/10.1007/s00005-012-0171-4.
    • (2012) Arch. Immunol. Ther. Exp. , vol.60 , pp. 173-181
    • O'Brien, T.F.1    Zhong, X.P.2
  • 21
    • 77953897189 scopus 로고    scopus 로고
    • Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways
    • Lee K, Gudapati P, Dragovic S, Spencer C, Joyce S, Killeen N, Magnuson MA, Boothby M. 2010. Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. Immunity 32:743-753. http://dx.doi.org/10.1016/j.immuni.2010.06.002.
    • (2010) Immunity , vol.32 , pp. 743-753
    • Lee, K.1    Gudapati, P.2    Dragovic, S.3    Spencer, C.4    Joyce, S.5    Killeen, N.6    Magnuson, M.A.7    Boothby, M.8
  • 23
    • 84896869317 scopus 로고    scopus 로고
    • Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function
    • Shin J, Wang S, Deng W, Wu J, Gao J, Zhong XP. 2014. Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function. Proc. Natl. Acad. Sci. U. S. A. 111: E776-E783. http://dx.doi.org/10.1073/pnas.1315435111.
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111
    • Shin, J.1    Wang, S.2    Deng, W.3    Wu, J.4    Gao, J.5    Zhong, X.P.6
  • 24
    • 84881192927 scopus 로고    scopus 로고
    • mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function
    • Zeng H, Yang K, Cloer C, Neale G, Vogel P, Chi H. 2013. mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function. Nature 499:485-490. http://dx.doi.org/10.1038/nature12297.
    • (2013) Nature , vol.499 , pp. 485-490
    • Zeng, H.1    Yang, K.2    Cloer, C.3    Neale, G.4    Vogel, P.5    Chi, H.6
  • 27
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • Inoki K, Li Y, Zhu T, Wu J, Guan KL. 2002. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 4:648-657. http://dx.doi.org/10.1038/ncb839.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 28
    • 17844369428 scopus 로고    scopus 로고
    • The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination
    • Benvenuto G, Li S, Brown SJ, Braverman R, Vass WC, Cheadle JP, Halley DJ, Sampson JR, Wienecke R, DeClue JE. 2000. The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination. Oncogene 19:6306-6316. http://dx.doi.org/10.1038/sj.onc.1204009.
    • (2000) Oncogene , vol.19 , pp. 6306-6316
    • Benvenuto, G.1    Li, S.2    Brown, S.J.3    Braverman, R.4    Vass, W.C.5    Cheadle, J.P.6    Halley, D.J.7    Sampson, J.R.8    Wienecke, R.9    DeClue, J.E.10
  • 29
    • 33646854721 scopus 로고    scopus 로고
    • TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase
    • Chong-Kopera H, Inoki K, Li Y, Zhu T, Garcia-Gonzalo FR, Rosa JL, Guan KL. 2006. TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase. J. Biol. Chem. 281:8313-8316. http://dx.doi.org/10.1074/jbc.C500451200.
    • (2006) J. Biol. Chem. , vol.281 , pp. 8313-8316
    • Chong-Kopera, H.1    Inoki, K.2    Li, Y.3    Zhu, T.4    Garcia-Gonzalo, F.R.5    Rosa, J.L.6    Guan, K.L.7
  • 30
    • 0043127125 scopus 로고    scopus 로고
    • Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
    • Inoki K, Li Y, Xu T, Guan KL. 2003. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev. 17:1829-1834. http://dx.doi.org/10.1101/gad.1110003.
    • (2003) Genes Dev. , vol.17 , pp. 1829-1834
    • Inoki, K.1    Li, Y.2    Xu, T.3    Guan, K.L.4
  • 31
    • 44449161481 scopus 로고    scopus 로고
    • The TSC1-TSC2 complex: a molecular switchboard controlling cell growth
    • Huang J, Manning BD. 2008. The TSC1-TSC2 complex: a molecular switchboard controlling cell growth. Biochem. J. 412:179-190. http://dx.doi.org/10.1042/BJ20080281.
    • (2008) Biochem. J. , vol.412 , pp. 179-190
    • Huang, J.1    Manning, B.D.2
  • 33
    • 80051997049 scopus 로고    scopus 로고
    • The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function
    • Yang K, Neale G, Green DR, He W, Chi H. 2011. The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function. Nat. Immunol. 12:888-897. http://dx.doi.org/10.1038/ni.2068.
    • (2011) Nat. Immunol. , vol.12 , pp. 888-897
    • Yang, K.1    Neale, G.2    Green, D.R.3    He, W.4    Chi, H.5
  • 34
    • 80051617288 scopus 로고    scopus 로고
    • The tuberous sclerosis complex-mammalian target of rapamycin pathway maintains the quiescence and survival of naive T cells
    • Wu Q, Liu Y, Chen C, Ikenoue T, Qiao Y, Li CS, Li W, Guan KL, Zheng P. 2011. The tuberous sclerosis complex-mammalian target of rapamycin pathway maintains the quiescence and survival of naive T cells. J. Immunol. 187:1106-1112. http://dx.doi.org/10.4049/jimmunol.1003968.
    • (2011) J. Immunol. , vol.187 , pp. 1106-1112
    • Wu, Q.1    Liu, Y.2    Chen, C.3    Ikenoue, T.4    Qiao, Y.5    Li, C.S.6    Li, W.7    Guan, K.L.8    Zheng, P.9
  • 37
    • 84897518164 scopus 로고    scopus 로고
    • Tuberous sclerosis 1 promotes invariant NKT cell anergy and inhibits invariant NKT cellmediated antitumor immunity
    • Wu J, Shin J, Xie D, Wang H, Gao J, Zhong XP. 2014. Tuberous sclerosis 1 promotes invariant NKT cell anergy and inhibits invariant NKT cellmediated antitumor immunity. J. Immunol. 192:2643-2650. http://dx.doi.org/10.4049/jimmunol.1302076.
    • (2014) J. Immunol. , vol.192 , pp. 2643-2650
    • Wu, J.1    Shin, J.2    Xie, D.3    Wang, H.4    Gao, J.5    Zhong, X.P.6
  • 39
    • 79960724234 scopus 로고    scopus 로고
    • Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation and loss of marginal zone B cells
    • Benhamron S, Tirosh B. 2011. Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation and loss of marginal zone B cells. Eur. J. Immunol. 41:2390-2396. http://dx.doi.org/10.1002/eji.201041336.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 2390-2396
    • Benhamron, S.1    Tirosh, B.2
  • 40
    • 84880103374 scopus 로고    scopus 로고
    • Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promotingMHCclass II expression via IRF4 and CIITA
    • Pan H, O'Brien TF, Wright G, Yang J, Shin J, Wright KL, Zhong XP. 2013. Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promotingMHCclass II expression via IRF4 and CIITA. J. Immunol. 191:699-707. http://dx.doi.org/10.4049/jimmunol.1201443.
    • (2013) J. Immunol. , vol.191 , pp. 699-707
    • Pan, H.1    O'Brien, T.F.2    Wright, G.3    Yang, J.4    Shin, J.5    Wright, K.L.6    Zhong, X.P.7
  • 41
    • 84860333507 scopus 로고    scopus 로고
    • The role of tuberous sclerosis complex 1 in regulating innate immunity
    • Pan H, O'Brien TF, Zhang P, Zhong XP. 2012. The role of tuberous sclerosis complex 1 in regulating innate immunity. J. Immunol. 188: 3658-3666. http://dx.doi.org/10.4049/jimmunol.1102187.
    • (2012) J. Immunol. , vol.188 , pp. 3658-3666
    • Pan, H.1    O'Brien, T.F.2    Zhang, P.3    Zhong, X.P.4
  • 42
    • 84859592965 scopus 로고    scopus 로고
    • Regulation of mast cell survival and function by tuberous sclerosis complex 1
    • Shin J, Pan H, Zhong XP. 2012. Regulation of mast cell survival and function by tuberous sclerosis complex 1. Blood 119:3306-3314. http://dx.doi.org/10.1182/blood-2011-05-353342.
    • (2012) Blood , vol.119 , pp. 3306-3314
    • Shin, J.1    Pan, H.2    Zhong, X.P.3
  • 43
    • 84855869698 scopus 로고    scopus 로고
    • Probing CD8 T cell responses with Listeria monocytogenes infection
    • Condotta SA, Richer MJ, Badovinac VP, Harty JT. 2012. Probing CD8 T cell responses with Listeria monocytogenes infection. Adv. Immunol. 113:51-80. http://dx.doi.org/10.1016/B978-0-12-394590-7.00005-1.
    • (2012) Adv. Immunol. , vol.113 , pp. 51-80
    • Condotta, S.A.1    Richer, M.J.2    Badovinac, V.P.3    Harty, J.T.4
  • 44
    • 0029003462 scopus 로고
    • Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity
    • Shen H, Slifka MK, Matloubian M, Jensen ER, Ahmed R, Miller JF. 1995. Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity. Proc. Natl. Acad. Sci. U. S. A. 92:3987-3991. http://dx.doi.org/10.1073/pnas.92.9.3987.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 3987-3991
    • Shen, H.1    Slifka, M.K.2    Matloubian, M.3    Jensen, E.R.4    Ahmed, R.5    Miller, J.F.6
  • 45
    • 0035284749 scopus 로고    scopus 로고
    • Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection
    • Pope C, Kim SK, Marzo A, Masopust D, Williams K, Jiang J, Shen H, Lefrancois L. 2001. Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection. J. Immunol. 166:3402-3409. http://dx.doi.org/10.4049/jimmunol.166.5.3402.
    • (2001) J. Immunol. , vol.166 , pp. 3402-3409
    • Pope, C.1    Kim, S.K.2    Marzo, A.3    Masopust, D.4    Williams, K.5    Jiang, J.6    Shen, H.7    Lefrancois, L.8
  • 46
    • 43449134355 scopus 로고    scopus 로고
    • Distinct regulation of effector and memory T-cell differentiation
    • Kallies A. 2008. Distinct regulation of effector and memory T-cell differentiation. Immunol. Cell Biol. 86:325-332. http://dx.doi.org/10.1038/icb.2008.16.
    • (2008) Immunol. Cell Biol. , vol.86 , pp. 325-332
    • Kallies, A.1
  • 49
    • 16844382244 scopus 로고    scopus 로고
    • Chemokine-mediated control of T cell traffic in lymphoid and peripheral tissues
    • Ebert LM, Schaerli P, Moser B. 2005. Chemokine-mediated control of T cell traffic in lymphoid and peripheral tissues. Mol. Immunol. 42:799-809. http://dx.doi.org/10.1016/j.molimm.2004.06.040.
    • (2005) Mol. Immunol. , vol.42 , pp. 799-809
    • Ebert, L.M.1    Schaerli, P.2    Moser, B.3
  • 50
    • 80054110065 scopus 로고    scopus 로고
    • Naive, effector and memory CD8 T-cell trafficking: parallels and distinctions
    • Nolz JC, Starbeck-Miller GR, Harty JT. 2011. Naive, effector and memory CD8 T-cell trafficking: parallels and distinctions. Immunotherapy 3:1223-1233. http://dx.doi.org/10.2217/imt.11.100.
    • (2011) Immunotherapy , vol.3 , pp. 1223-1233
    • Nolz, J.C.1    Starbeck-Miller, G.R.2    Harty, J.T.3
  • 52
    • 0037059462 scopus 로고    scopus 로고
    • Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells
    • Szabo SJ, Sullivan BM, Stemmann C, Satoskar AR, Sleckman BP, Glimcher LH. 2002. Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science 295:338-342. http://dx.doi.org/10.1126/science.1065543.
    • (2002) Science , vol.295 , pp. 338-342
    • Szabo, S.J.1    Sullivan, B.M.2    Stemmann, C.3    Satoskar, A.R.4    Sleckman, B.P.5    Glimcher, L.H.6
  • 57
    • 78649853665 scopus 로고    scopus 로고
    • T-bet and eomesodermin are required for T cell-mediated antitumor immune responses
    • Zhu Y, Ju S, Chen E, Dai S, Li C, Morel P, Liu L, Zhang X, Lu B. 2010. T-bet and eomesodermin are required for T cell-mediated antitumor immune responses. J. Immunol. 185:3174-3183. http://dx.doi.org/10.4049/jimmunol.1000749.
    • (2010) J. Immunol. , vol.185 , pp. 3174-3183
    • Zhu, Y.1    Ju, S.2    Chen, E.3    Dai, S.4    Li, C.5    Morel, P.6    Liu, L.7    Zhang, X.8    Lu, B.9
  • 58
    • 0037124341 scopus 로고    scopus 로고
    • Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells
    • Becker TC, Wherry EJ, Boone D, Murali-Krishna K, Antia R, Ma A, Ahmed R. 2002. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J. Exp. Med. 195:1541-1548. http://dx.doi.org/10.1084/jem.20020369.
    • (2002) J. Exp. Med. , vol.195 , pp. 1541-1548
    • Becker, T.C.1    Wherry, E.J.2    Boone, D.3    Murali-Krishna, K.4    Antia, R.5    Ma, A.6    Ahmed, R.7
  • 59
    • 0037093844 scopus 로고    scopus 로고
    • Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells
    • Schluns KS, Williams K, Ma A, Zheng XX, Lefrancois L. 2002. Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J. Immunol. 168:4827-4831. http://dx.doi.org/10.4049/jimmunol.168.10.4827.
    • (2002) J. Immunol. , vol.168 , pp. 4827-4831
    • Schluns, K.S.1    Williams, K.2    Ma, A.3    Zheng, X.X.4    Lefrancois, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.