Tsc1 promotes the differentiation of memory CD8+T cells via orchestrating the transcriptional and metabolic programs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 41, 2014, Pages 14858-14863

  Shrestha, Sharad ^a,b   Yang, Kai ^a   Wei, Jun ^a   Karmaus, Peer W F ^a   Neale, Geoffrey ^a   Chi, Hongbo ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Glycolysis; Immune response; Oxidative phosphorylation; T cell memory

Indexed keywords

ANTIGEN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE; TUBEROUS SCLEROSIS COMPLEX 1 PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL; C57BL MOUSE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CYTOLOGY; DEFICIENCY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM;

ANIMALS; ANTIGENS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; IMMUNOLOGIC MEMORY; MICE, INBRED C57BL; MULTIPROTEIN COMPLEXES; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 84907886513     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1404264111     Document Type: Article

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